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5IPQ
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BU of 5ipq by Molmil
Cryo-EM structure of GluN1/GluN2B NMDA receptor in the DCKA/D-APV-bound conformation, state 2
分子名称: Ionotropic glutamate receptor subunit NR2B, N-methyl-D-aspartate receptor subunit NR1-8a
著者Zhu, S, Stein, A.R, Yoshioka, C, Lee, C.H, Goehring, A, Mchaourab, S.H, Gouaux, E.
登録日2016-03-09
公開日2016-04-20
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (13.5 Å)
主引用文献Mechanism of NMDA Receptor Inhibition and Activation.
Cell, 165, 2016
5IOU
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BU of 5iou by Molmil
Cryo-EM structure of GluN1/GluN2B NMDA receptor in the glutamate/glycine-bound conformation
分子名称: GLUTAMIC ACID, GLYCINE, Ionotropic glutamate receptor subunit NR2B, ...
著者Zhu, S, Stein, A.R, Yoshioka, C, Lee, C.H, Goehring, A, Mchaourab, S.H, Gouaux, E.
登録日2016-03-09
公開日2016-04-20
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (7 Å)
主引用文献Mechanism of NMDA Receptor Inhibition and Activation.
Cell, 165, 2016
5IPU
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BU of 5ipu by Molmil
Cryo-EM structure of GluN1/GluN2B NMDA receptor in the DCKA/D-APV-bound conformation, state 6
分子名称: Ionotropic glutamate receptor subunit NR2B, N-methyl-D-aspartate receptor subunit NR1-8a
著者Zhu, S, Stein, A.R, Yoshioka, C, Lee, C.H, Goehring, A, Mchaourab, S.H, Gouaux, E.
登録日2016-03-09
公開日2016-04-20
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (15.4 Å)
主引用文献Mechanism of NMDA Receptor Inhibition and Activation.
Cell, 165, 2016
5I6X
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BU of 5i6x by Molmil
X-ray structure of the ts3 human serotonin transporter complexed with paroxetine at the central site
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 8B6 antibody, heavy chain, ...
著者Coleman, J.A, Green, E.M, Gouaux, E.
登録日2016-02-16
公開日2016-04-13
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.14 Å)
主引用文献X-ray structures and mechanism of the human serotonin transporter.
Nature, 532, 2016
3IJ4
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BU of 3ij4 by Molmil
Cesium sites in the crystal structure of a functional acid sensing ion channel in the desensitized state
分子名称: Amiloride-sensitive cation channel 2, neuronal, CESIUM ION, ...
著者Gonzales, E.B, Gouaux, E.
登録日2009-08-03
公開日2009-11-10
最終更新日2024-11-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Pore architecture and ion sites in acid-sensing ion channels and P2X receptors.
Nature, 460, 2009
5I66
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BU of 5i66 by Molmil
X-ray structure of the Fab fragment of 8B6, a murine monoclonal antibody specific for the human serotonin transporter
分子名称: 8B6 antibody, heavy chain, light chain
著者Coleman, J.A, Green, E.M, Gouaux, E.
登録日2016-02-16
公開日2016-04-13
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.624 Å)
主引用文献X-ray structures and mechanism of the human serotonin transporter.
Nature, 532, 2016
5I75
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BU of 5i75 by Molmil
X-ray structure of the ts3 human serotonin transporter complexed with s-citalopram at the central site and Br-citalopram at the allosteric site
分子名称: (1S)-1-(4-bromophenyl)-1-[3-(dimethylamino)propyl]-1,3-dihydro-2-benzofuran-5-carbonitrile, (1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Coleman, J.A, Green, E.M, Gouaux, E.
登録日2016-02-16
公開日2016-04-13
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.49 Å)
主引用文献X-ray structures and mechanism of the human serotonin transporter.
Nature, 532, 2016
5IPS
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BU of 5ips by Molmil
Cryo-EM structure of GluN1/GluN2B NMDA receptor in the DCKA/D-APV-bound conformation, state 4
分子名称: Ionotropic glutamate receptor subunit NR2B, N-methyl-D-aspartate receptor subunit NR1-8a
著者Zhu, S, Stein, A.R, Yoshioka, C, Lee, C.H, Goehring, A, Mchaourab, S.H, Gouaux, E.
登録日2016-03-09
公開日2016-04-20
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (13.5 Å)
主引用文献Mechanism of NMDA Receptor Inhibition and Activation.
Cell, 165, 2016
3H5W
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BU of 3h5w by Molmil
Crystal structure of the GluR2-ATD in space group P212121 without solvent
分子名称: Glutamate receptor 2
著者Jin, R, Singh, S.K, Gu, S, Furukawa, H, Sobolevsky, A, Zhou, J, Jin, Y, Gouaux, E.
登録日2009-04-22
公開日2009-06-09
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.686 Å)
主引用文献Crystal structure and association behaviour of the GluR2 amino-terminal domain.
Embo J., 28, 2009
3H5V
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BU of 3h5v by Molmil
Crystal structure of the GluR2-ATD
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2
著者Jin, R, Singh, S.K, Gu, S, Furukawa, H, Sobolevsky, A, Zhou, J, Jin, Y, Gouaux, E.
登録日2009-04-22
公開日2009-06-09
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Crystal structure and association behaviour of the GluR2 amino-terminal domain.
Embo J., 28, 2009
1MY1
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BU of 1my1 by Molmil
crystal titration experiments (AMPA co-crystals soaked in 10 nM BrW)
分子名称: GLUTAMATE RECEPTOR 2, ZINC ION
著者Jin, R, Gouaux, E.
登録日2002-10-03
公開日2003-06-10
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal
Biochemistry, 42, 2003
1MQG
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BU of 1mqg by Molmil
Crystal Structure of the GluR2 Ligand Binding Core (S1S2J) in Complex with Iodo-Willardiine at 2.15 Angstroms Resolution
分子名称: 2-AMINO-3-(5-IODO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, GLYCEROL, SULFATE ION, ...
著者Jin, R, Banke, T.G, Mayer, M.L, Traynelis, S.F, Gouaux, E.
登録日2002-09-16
公開日2003-08-05
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural basis for partial agonist action at ionotropic glutamate receptors
Nat.Neurosci., 6, 2003
1MXX
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BU of 1mxx by Molmil
crystal titration experiments (AMPA co-crystals soaked in 100 uM BrW)
分子名称: GLUTAMATE RECEPTOR 2, ZINC ION
著者Jin, R, Gouaux, E.
登録日2002-10-03
公開日2003-06-10
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal
Biochemistry, 42, 2003
1MY3
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BU of 1my3 by Molmil
crystal structure of glutamate receptor ligand-binding core in complex with bromo-willardiine in the Zn crystal form
分子名称: 2-AMINO-3-(5-BROMO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, GLUTAMATE RECEPTOR 2, ZINC ION
著者Jin, R, Gouaux, E.
登録日2002-10-03
公開日2003-06-10
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal
Biochemistry, 42, 2003
1MQJ
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BU of 1mqj by Molmil
Crystal structure of the GluR2 ligand binding core (S1S2J) in complex with willardiine at 1.65 angstroms resolution
分子名称: 2-AMINO-3-(2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, ZINC ION, glutamate receptor 2
著者Jin, R, Banke, T.G, Mayer, M.L, Traynelis, S.F, Gouaux, E.
登録日2002-09-16
公開日2003-08-05
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural basis for partial agonist action at ionotropic glutamate receptors
Nat.Neurosci., 6, 2003
3JAF
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BU of 3jaf by Molmil
Structure of alpha-1 glycine receptor by single particle electron cryo-microscopy, glycine/ivermectin-bound state
分子名称: (2aE,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17 -oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacy clooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycine receptor subunit alphaZ1
著者Du, J, Lu, W, Wu, S.P, Cheng, Y.F, Gouaux, E.
登録日2015-06-08
公開日2015-09-09
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Glycine receptor mechanism elucidated by electron cryo-microscopy.
Nature, 526, 2015
3TT3
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BU of 3tt3 by Molmil
Crystal Structure of LeuT in the inward-open conformation in complex with Fab
分子名称: Leucine transporter LeuT, mouse monoclonal 1gG1 Fab fragment, heavy chain, ...
著者Krishnamurthy, H, Gouaux, E.
登録日2011-09-13
公開日2012-01-04
最終更新日2024-11-27
実験手法X-RAY DIFFRACTION (3.22 Å)
主引用文献X-ray structures of LeuT in substrate-free outward-open and apo inward-open states.
Nature, 481, 2012
3TU0
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BU of 3tu0 by Molmil
Crystal structure of T355V, S354A, K288A LeuT mutant in complex with alanine and sodium
分子名称: ALANINE, Leucine transporter LeuT, SODIUM ION
著者Krishnamurthy, H, Gouaux, E.
登録日2011-09-15
公開日2012-01-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.994 Å)
主引用文献X-ray structures of LeuT in substrate-free outward-open and apo inward-open states.
Nature, 481, 2012
3TT1
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BU of 3tt1 by Molmil
Crystal Structure of LeuT in the outward-open conformation in complex with Fab
分子名称: Leucine transporter LeuT, SODIUM ION, mouse monoclonal 1gG2a Fab fragment, ...
著者Krishnamurthy, H, Gouaux, E.
登録日2011-09-13
公開日2012-01-04
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.099 Å)
主引用文献X-ray structures of LeuT in substrate-free outward-open and apo inward-open states.
Nature, 481, 2012
3USI
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BU of 3usi by Molmil
Crystal structure of LeuT bound to L-leucine in space group P2 from lipid bicelles
分子名称: LEUCINE, SODIUM ION, Transporter
著者Wang, H, Elferich, J, Gouaux, E.
登録日2011-11-23
公開日2012-01-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.106 Å)
主引用文献Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context.
Nat.Struct.Mol.Biol., 19, 2012
3USK
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BU of 3usk by Molmil
Crystal structure of LeuT bound to L-leucine in space group P21 from lipid bicelles
分子名称: LEUCINE, SODIUM ION, Transporter
著者Wang, H, Elferich, J, Gouaux, E.
登録日2011-11-23
公開日2012-01-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (4.5 Å)
主引用文献Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context.
Nat.Struct.Mol.Biol., 19, 2012
3USL
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BU of 3usl by Molmil
Crystal Structure of LeuT bound to L-selenomethionine in space group C2 from lipid bicelles
分子名称: ACETATE ION, IODIDE ION, PHOSPHOCHOLINE, ...
著者Wang, H, Elferich, J, Gouaux, E.
登録日2011-11-23
公開日2012-01-11
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context.
Nat.Struct.Mol.Biol., 19, 2012
3USO
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BU of 3uso by Molmil
Crystal structure of LeuT bound to L-selenomethionine in space group P21212 from lipid bicelles
分子名称: SELENOMETHIONINE, SODIUM ION, Transporter
著者Wang, H, Elferich, J, Gouaux, E.
登録日2011-11-23
公開日2012-01-11
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (4.5 Å)
主引用文献Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context.
Nat.Struct.Mol.Biol., 19, 2012
3USJ
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BU of 3usj by Molmil
Crystal structure of LeuT bound to L-leucine in space group P21 from lipid bicelles
分子名称: LEUCINE, SODIUM ION, Transporter
著者Wang, H, Elferich, J, Gouaux, E.
登録日2011-11-23
公開日2012-01-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context.
Nat.Struct.Mol.Biol., 19, 2012
3USM
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BU of 3usm by Molmil
Crystal Structure of LeuT bound to L-selenomethionine in space group C2 from lipid bicelles (collected at 1.2 A)
分子名称: IODIDE ION, PHOSPHOCHOLINE, SELENOMETHIONINE, ...
著者Wang, H, Elferich, J, Gouaux, E.
登録日2011-11-23
公開日2012-01-11
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (3.008 Å)
主引用文献Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context.
Nat.Struct.Mol.Biol., 19, 2012

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