6SOO
 
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2ZIV
 | | Crystal structure of the Mus81-Eme1 complex | | 分子名称: | Crossover junction endonuclease EME1, Mus81 protein | | 著者 | Chang, J.H, Kim, J.J, Choi, J.M, Lee, J.H, Cho, Y. | | 登録日 | 2008-02-25 | | 公開日 | 2008-04-29 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of the Mus81-Eme1 complex
Genes Dev., 22, 2008
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6SP1
 | | KEAP1 IN COMPLEX WITH COMPOUND 6 | | 分子名称: | (1~{S},2~{R})-2-[[(1~{S})-1-[[1,3-bis(oxidanylidene)isoindol-2-yl]methyl]-5-(2-hydroxyethyloxy)-3,4-dihydro-1~{H}-isoquinolin-2-yl]carbonyl]cyclohexane-1-carboxylic acid, ACETATE ION, Kelch-like ECH-associated protein 1 | | 著者 | Ontoria, J.M, Biancofiore, I, Fezzardi, P, Torrente de Haro, E, Colarusso, S, Bianchi, E, Andreini, M, Patsilinakos, A, Summa, V, Pacifici, R, Munoz-Sanjuan, I, Park, L, Bresciani, A, Dominguez, C, Toledo-Sherman, L, Harper, S. | | 登録日 | 2019-08-30 | | 公開日 | 2020-06-03 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | Combined Peptide and Small-Molecule Approach toward Nonacidic THIQ Inhibitors of the KEAP1/NRF2 Interaction.
Acs Med.Chem.Lett., 11, 2020
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2ZJQ
 | | Interaction of L7 with L11 induced by Microccocin binding to the Deinococcus radiodurans 50S subunit | | 分子名称: | 50S ribosomal protein L11, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | | 著者 | Harms, J.M, Wilson, D.N, Schluenzen, F, Connell, S.R, Stachelhaus, T, Zaborowska, Z, Spahn, C.M.T, Fucini, P. | | 登録日 | 2008-03-08 | | 公開日 | 2008-06-17 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Translational regulation via L11: molecular switches on the ribosome turned on and off by thiostrepton and micrococcin.
Mol.Cell, 30, 2008
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6T0S
 | | Bat Influenza A polymerase stuttering complex using 44-mer vRNA template with intact oligo(U) sequence | | 分子名称: | MAGNESIUM ION, Polymerase acidic protein, Polymerase basic protein 2, ... | | 著者 | Wandzik, J.M, Kouba, T, Cusack, S. | | 登録日 | 2019-10-03 | | 公開日 | 2020-04-15 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | | 主引用文献 | A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase.
Cell, 181, 2020
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6T0N
 | | Bat Influenza A polymerase pre-initiation complex | | 分子名称: | 3' vRNA, 5' vRNA, MAGNESIUM ION, ... | | 著者 | Wandzik, J.M, Kouba, T, Cusack, S. | | 登録日 | 2019-10-03 | | 公開日 | 2020-04-15 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (2.54 Å) | | 主引用文献 | A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase.
Cell, 181, 2020
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2Z26
 | | Thr110Ala dihydroorotase from E. coli | | 分子名称: | (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, Dihydroorotase, MALONATE ION, ... | | 著者 | Lee, M, Maher, M.J, Guss, J.M. | | 登録日 | 2007-05-17 | | 公開日 | 2007-10-09 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.29 Å) | | 主引用文献 | Kinetic and Structural Analysis of Mutant Escherichia coli Dihydroorotases: A Flexible Loop Stabilizes the Transition State
Biochemistry, 46, 2007
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2Z28
 | | Thr109Val dihydroorotase from E. coli | | 分子名称: | (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, Dihydroorotase, N-CARBAMOYL-L-ASPARTATE, ... | | 著者 | Lee, M, Maher, M.J, Guss, J.M. | | 登録日 | 2007-05-17 | | 公開日 | 2007-10-09 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Kinetic and Structural Analysis of Mutant Escherichia coli Dihydroorotases: A Flexible Loop Stabilizes the Transition State
Biochemistry, 46, 2007
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2Z24
 | | Thr110Ser dihydroorotase from E. coli | | 分子名称: | (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, Dihydroorotase, N-CARBAMOYL-L-ASPARTATE, ... | | 著者 | Lee, M, Maher, M.J, Guss, J.M. | | 登録日 | 2007-05-17 | | 公開日 | 2007-10-09 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Kinetic and Structural Analysis of Mutant Escherichia coli Dihydroorotases: A Flexible Loop Stabilizes the Transition State
Biochemistry, 46, 2007
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2ZXX
 | | Crystal structure of Cdt1/geminin complex | | 分子名称: | DNA replication factor Cdt1, Geminin | | 著者 | Cho, Y, Lee, C, Hong, B.S, Choi, J.M. | | 登録日 | 2009-01-08 | | 公開日 | 2009-02-17 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural basis for inhibition of the replication licensing factor Cdt1 by geminin
Nature, 430, 2004
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2YJ8
 | | CATHEPSIN L WITH A NITRILE INHIBITOR | | 分子名称: | (2S,4R)-4-(2-chlorophenyl)sulfonyl-N-[1-(iminomethyl)cyclopropyl]-1-[1-(4-iodophenyl)cyclopropyl]carbonyl-pyrrolidine-2-carboxamide, CATHEPSIN L1, GLYCEROL | | 著者 | Banner, D.W, Benz, J.M, Haap, W. | | 登録日 | 2011-05-19 | | 公開日 | 2011-11-23 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Halogen Bonding at the Active Sites of Human Cathepsin L and Mek1 Kinase: Efficient Interactions in Different Environments.
Chemmedchem, 6, 2011
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2Y7C
 | | Atomic model of the Ocr-bound methylase complex from the Type I restriction-modification enzyme EcoKI (M2S1). Based on fitting into EM map 1534. | | 分子名称: | GENE 0.3 PROTEIN, TYPE I RESTRICTION ENZYME ECOKI M PROTEIN, TYPE-1 RESTRICTION ENZYME ECOKI SPECIFICITY PROTEIN | | 著者 | Kennaway, C.K, Obarska-Kosinska, A, White, J.H, Tuszynska, I, Cooper, L.P, Bujnicki, J.M, Trinick, J, Dryden, D.T.F. | | 登録日 | 2011-01-31 | | 公開日 | 2011-02-09 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (18 Å) | | 主引用文献 | The Structure of M.Ecoki Type I DNA Methyltransferase with a DNA Mimic Antirestriction Protein.
Nucleic Acids Res., 37, 2009
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2YBD
 | | Crystal structure of probable had family hydrolase from pseudomonas fluorescens pf-5 with bound phosphate | | 分子名称: | HYDROLASE, HALOACID DEHALOGENASE-LIKE FAMILY, MAGNESIUM ION, ... | | 著者 | Vetting, M.W, Patskovsky, Y, Toro, R, Freeman, J, Miller, S, Sauder, J.M, Burley, S.K, Dunaway-Mariano, D, Allen, K.N, Gerlt, J.A, Almo, S.C. | | 登録日 | 2011-03-03 | | 公開日 | 2011-03-16 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | | 主引用文献 | Crystal Structure of Probable Had Family Hydrolase from Pseudomonas Fluorescens Pf-5 with Bound Phosphate
To be Published
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2YIH
 | | Structure of a Paenibacillus polymyxa Xyloglucanase from GH family 44 with Xyloglucan | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, CEL44C, ... | | 著者 | Ariza, A, Eklof, J.M, Spadiut, O, Offen, W.A, Roberts, S.M, Besenmatter, W, Friis, E.P, Skjot, M, Wilson, K.S, Brumer, H, Davies, G. | | 登録日 | 2011-05-13 | | 公開日 | 2011-06-08 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure and Activity of Paenibacillus Polymyxa Xyloglucanase from Glycoside Hydrolase Family 44.
J.Biol.Chem., 286, 2011
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2YJB
 | | CATHEPSIN L WITH A NITRILE INHIBITOR | | 分子名称: | (2S,4R)-4-(2-chlorophenyl)sulfonyl-N-[1-(iminomethyl)cyclopropyl]-1-[1-[4-(trifluoromethyl)phenyl]cyclopropyl]carbonyl-pyrrolidine-2-carboxamide, CATHEPSIN L1, GLYCEROL | | 著者 | Banner, D.W, Benz, J.M, Haap, W. | | 登録日 | 2011-05-19 | | 公開日 | 2011-11-23 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Halogen Bonding at the Active Sites of Human Cathepsin L and Mek1 Kinase: Efficient Interactions in Different Environments.
Chemmedchem, 6, 2011
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2YMD
 | | Crystal structure of a mutant binding protein (5HTBP-AChBP) in complex with serotonin (5-hydroxytryptamine) | | 分子名称: | GLYCEROL, PHOSPHATE ION, SEROTONIN, ... | | 著者 | Kesters, D, Thompson, A.J, Brams, M, Elk, R.v, Spurny, R, Geitmann, M, Villalgordo, J.M, Guskov, A, Danielson, U.H, Lummis, S.C.R, Smit, A.B, Ulens, C. | | 登録日 | 2012-10-09 | | 公開日 | 2012-12-12 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Structural Basis of Ligand Recognition in 5-Ht(3) Receptors.
Embo Rep., 14, 2013
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2Y9F
 | | High-resolution Structural Insights on the Sugar-recognition and Fusion Tag Properties of a Versatile b-Trefoil Lectin Domain | | 分子名称: | HEMOLYTIC LECTIN LSLA | | 著者 | Angulo, I, Acebron, I, de las Rivas, B, Munoz, R, Rodriguez, J.I, Menendez, M, Garcia, P, Tateno, H, Goldstein, I.J, Perez-Agote, B, Mancheno, J.M. | | 登録日 | 2011-02-14 | | 公開日 | 2011-10-12 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | | 主引用文献 | High-Resolution Structural Insights on the Sugar-Recognition and Fusion Tag Properties of a Versatile Beta-Trefoil Lectin Domain from the Mushroom Laetiporus Sulphureus.
Glycobiology, 21, 2011
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2Y5S
 | | Crystal structure of Burkholderia cenocepacia dihydropteroate synthase complexed with 7,8-dihydropteroate. | | 分子名称: | 1,2-ETHANEDIOL, 7,8-DIHYDROPTEROATE, CHLORIDE ION, ... | | 著者 | Morgan, R.E, Batot, G.O, Dement, J.M, Rao, V.A, Eadsforth, T.C, Hunter, W.N. | | 登録日 | 2011-01-17 | | 公開日 | 2011-01-26 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal Structures of Burkholderia Cenocepacia Dihydropteroate Synthase in the Apo-Form and Complexed with the Product 7,8-Dihydropteroate.
Bmc Struct.Biol., 11, 2011
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2Z2A
 | | Thr109Gly dihydroorotase from E. coli | | 分子名称: | (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, Dihydroorotase, N-CARBAMOYL-L-ASPARTATE, ... | | 著者 | Lee, M, Maher, M.J, Guss, J.M. | | 登録日 | 2007-05-17 | | 公開日 | 2007-10-09 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Kinetic and Structural Analysis of Mutant Escherichia coli Dihydroorotases: A Flexible Loop Stabilizes the Transition State
Biochemistry, 46, 2007
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2Z8N
 | | Structural basis for the catalytic mechanism of phosphothreonine lyase | | 分子名称: | 27.5 kDa virulence protein, SULFATE ION | | 著者 | Chen, L, Wang, H, Gu, L, Huang, N, Zhou, J.M, Chai, J. | | 登録日 | 2007-09-07 | | 公開日 | 2007-12-18 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural basis for the catalytic mechanism of phosphothreonine lyase.
Nat.Struct.Mol.Biol., 15, 2008
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2Z29
 | | Thr109Ala dihydroorotase from E. coli | | 分子名称: | (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, Dihydroorotase, N-CARBAMOYL-L-ASPARTATE, ... | | 著者 | Lee, M, Maher, M.J, Guss, J.M. | | 登録日 | 2007-05-17 | | 公開日 | 2007-10-09 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Kinetic and Structural Analysis of Mutant Escherichia coli Dihydroorotases: A Flexible Loop Stabilizes the Transition State
Biochemistry, 46, 2007
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3A60
 | | Crystal structure of unphosphorylated p70S6K1 (Form I) | | 分子名称: | Ribosomal protein S6 kinase beta-1, STAUROSPORINE | | 著者 | Sunami, T, Byrne, N, Diehl, R.E, Funabashi, K, Hall, D.L, Ikuta, M, Patel, S.B, Shipman, J.M, Smith, R.F, Takahashi, I, Zugay-Murphy, J, Iwasawa, Y, Lumb, K.J, Munshi, S.K, Sharma, S. | | 登録日 | 2009-08-17 | | 公開日 | 2009-10-27 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural basis of human p70 ribosomal S6 kinase-1 regulation by activation loop phosphorylation.
J.Biol.Chem., 285, 2010
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5JNF
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5J6Z
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6TH6
 | | Cryo-EM Structure of T. kodakarensis 70S ribosome | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Matzov, D, Sas-Chen, A, Thomas, J.M, Santangelo, T, Meier, J.L, Schwartz, S, Shalev-Benami, M. | | 登録日 | 2019-11-18 | | 公開日 | 2020-07-29 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (2.55 Å) | | 主引用文献 | Dynamic RNA acetylation revealed by quantitative cross-evolutionary mapping.
Nature, 583, 2020
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