3FZH
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![BU of 3fzh by Molmil](/molmil-images/mine/3fzh) | Crystal Structures of Hsc70/Bag1 in Complex with Small Molecule Inhibitors | 分子名称: | (2R,3R,4S,5R)-2-(6,8-diaminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol, BAG family molecular chaperone regulator 1, Heat shock cognate 71 kDa protein | 著者 | Dokurno, P, Williamson, D.S, Murray, J.B, Surgenor, A.E. | 登録日 | 2009-01-26 | 公開日 | 2009-03-17 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Novel adenosine-derived inhibitors of 70 kDa heat shock protein, discovered through structure-based design J.Med.Chem., 52, 2009
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9BDX
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![BU of 9bdx by Molmil](/molmil-images/mine/9bdx) | NF-kappaB RelA homo-dimer bound to CG-centric kappaB DNA | 分子名称: | DNA (5'-D(*AP*TP*CP*AP*CP*TP*GP*GP*AP*AP*GP*TP*TP*CP*CP*CP*AP*GP*T)-3'), DNA (5'-D(P*AP*CP*TP*GP*GP*GP*AP*AP*CP*TP*TP*CP*CP*AP*GP*TP*GP*AP*T)-3'), Transcription factor p65 | 著者 | Biswas, T, Shahabi, S, Tsodikov, O.V, Ghosh, G. | 登録日 | 2024-04-12 | 公開日 | 2024-04-24 | 最終更新日 | 2024-06-12 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Transient interactions modulate the affinity of NF-kappa B transcription factors for DNA. Proc.Natl.Acad.Sci.USA, 121, 2024
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3CN6
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![BU of 3cn6 by Molmil](/molmil-images/mine/3cn6) | Crystal structure of the Spinach Aquaporin SoPIP2;1 S274E mutant | 分子名称: | Aquaporin, CADMIUM ION | 著者 | Nyblom, M, Alfredsson, A, Hallgren, K, Hedfalk, K, Neutze, R, Tornroth-Horsefield, S. | 登録日 | 2008-03-25 | 公開日 | 2009-02-24 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Structural and functional analysis of SoPIP2;1 mutants adds insight into plant aquaporin gating. J.Mol.Biol., 387, 2009
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9BDW
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![BU of 9bdw by Molmil](/molmil-images/mine/9bdw) | NF-kappaB RelA homo-dimer bound to GC-centric kappaB DNA | 分子名称: | DNA (5'-D(P*AP*CP*TP*GP*GP*GP*AP*AP*GP*TP*TP*CP*CP*AP*GP*TP*GP*AP*T)-3'), DNA (5'-D(P*AP*TP*CP*AP*CP*TP*GP*GP*AP*AP*CP*TP*TP*CP*CP*CP*AP*GP*T)-3'), SULFATE ION, ... | 著者 | Biswas, T, Shahabi, S, Tsodikov, O.V, Huang, D, Ghosh, G. | 登録日 | 2024-04-12 | 公開日 | 2024-04-24 | 最終更新日 | 2024-06-12 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Transient interactions modulate the affinity of NF-kappa B transcription factors for DNA. Proc.Natl.Acad.Sci.USA, 121, 2024
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9BDV
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![BU of 9bdv by Molmil](/molmil-images/mine/9bdv) | NF-kappaB RelA homo-dimer bound to TA-centric kappaB DNA | 分子名称: | DNA (5'-D(*AP*TP*CP*AP*CP*TP*GP*GP*AP*AP*AP*TP*TP*CP*CP*CP*AP*GP*T)-3'), DNA (5'-D(P*AP*CP*TP*GP*GP*GP*AP*AP*TP*TP*TP*CP*CP*AP*GP*TP*GP*AP*T)-3'), SULFATE ION, ... | 著者 | Biswas, T, Shahabi, S, Tsodikov, O.V. | 登録日 | 2024-04-12 | 公開日 | 2024-04-24 | 最終更新日 | 2024-06-12 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Transient interactions modulate the affinity of NF-kappa B transcription factors for DNA. Proc.Natl.Acad.Sci.USA, 121, 2024
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9BDU
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![BU of 9bdu by Molmil](/molmil-images/mine/9bdu) | NF-kappaB RelA homo-dimer bound to AT-centric kappaB DNA | 分子名称: | DNA (5'-D(P*AP*CP*TP*GP*GP*GP*AP*AP*AP*TP*TP*CP*CP*AP*GP*TP*GP*AP*T)-3'), DNA (5'-D(P*AP*TP*CP*AP*CP*TP*GP*GP*AP*AP*TP*TP*TP*CP*CP*CP*AP*GP*T)-3'), SULFATE ION, ... | 著者 | Biswas, T, Huang, D, Ghosh, G. | 登録日 | 2024-04-12 | 公開日 | 2024-04-24 | 最終更新日 | 2024-06-12 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Transient interactions modulate the affinity of NF-kappa B transcription factors for DNA. Proc.Natl.Acad.Sci.USA, 121, 2024
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3FZF
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![BU of 3fzf by Molmil](/molmil-images/mine/3fzf) | Crystal Structure of Hsc70/Bag1 in complex with ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, BAG family molecular chaperone regulator 1, Heat shock cognate 71 kDa protein | 著者 | Dokurno, P, Williamson, D.S, Murray, J.B, Surgenor, A.E. | 登録日 | 2009-01-26 | 公開日 | 2009-03-17 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Novel adenosine-derived inhibitors of 70 kDa heat shock protein, discovered through structure-based design J.Med.Chem., 52, 2009
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2I6K
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![BU of 2i6k by Molmil](/molmil-images/mine/2i6k) | Crystal structure of human type I IPP isomerase complexed with a substrate analog | 分子名称: | ACETIC ACID, AMINOETHANOLPYROPHOSPHATE, Isopentenyl-diphosphate delta-isomerase 1, ... | 著者 | Zhang, C, Wei, Z, Gong, W. | 登録日 | 2006-08-29 | 公開日 | 2007-06-05 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structures of human IPP isomerase: new insights into the catalytic mechanism J.Mol.Biol., 366, 2007
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7WSB
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![BU of 7wsb by Molmil](/molmil-images/mine/7wsb) | The ternary complex structure of FtmOx1 with a-ketoglutarate and 13-oxo-fumitremorgin B | 分子名称: | 13-Oxofumitremorgin B, 2-OXOGLUTARIC ACID, COBALT (II) ION, ... | 著者 | Wang, J, Wang, X.Y, Wang, Y.Y, Yan, W.P. | 登録日 | 2022-01-28 | 公開日 | 2022-07-06 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.87 Å) | 主引用文献 | Dissecting the Mechanism of the Nonheme Iron Endoperoxidase FtmOx1 Using Substrate Analogues. Jacs Au, 2, 2022
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6CKH
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![BU of 6ckh by Molmil](/molmil-images/mine/6ckh) | Manduca sexta Peptidoglycan Recognition Protein-1 | 分子名称: | Peptidoglycan-recognition protein | 著者 | Hu, Y. | 登録日 | 2018-02-28 | 公開日 | 2019-06-05 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The three-dimensional structure and recognition mechanism of Manduca sexta peptidoglycan recognition protein-1. Insect Biochem.Mol.Biol., 108, 2019
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6KG9
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![BU of 6kg9 by Molmil](/molmil-images/mine/6kg9) | |
6KGF
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![BU of 6kgf by Molmil](/molmil-images/mine/6kgf) | Crystal structure of CaDoc0917(R16D)-CaCohA2 complex at pH 8.2 | 分子名称: | And cellulose-binding endoglucanase family 9 CelL ortholog dockerin domain, CALCIUM ION, Probably cellulosomal scaffolding protein, ... | 著者 | Feng, Y, Yao, X. | 登録日 | 2019-07-11 | 公開日 | 2020-07-08 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Discovery and mechanism of a pH-dependent dual-binding-site switch in the interaction of a pair of protein modules. Sci Adv, 6, 2020
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3G49
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![BU of 3g49 by Molmil](/molmil-images/mine/3g49) | |
2HNK
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![BU of 2hnk by Molmil](/molmil-images/mine/2hnk) | Crystal structure of SAM-dependent O-methyltransferase from pathogenic bacterium Leptospira interrogans | 分子名称: | DI(HYDROXYETHYL)ETHER, S-ADENOSYL-L-HOMOCYSTEINE, SAM-dependent O-methyltransferase, ... | 著者 | Hou, X, Wei, Z, Gong, W. | 登録日 | 2006-07-13 | 公開日 | 2007-09-04 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of SAM-dependent O-methyltransferase from pathogenic bacterium Leptospira interrogans. J.Struct.Biol., 159, 2007
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3EAE
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![BU of 3eae by Molmil](/molmil-images/mine/3eae) | PWWP domain of human hepatoma-derived growth factor 2 (HDGF2) | 分子名称: | Hepatoma-derived growth factor-related protein 2 | 著者 | Amaya, M.F, Zeng, H, Mackenzie, F, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Wu, H, Structural Genomics Consortium (SGC) | 登録日 | 2008-08-25 | 公開日 | 2008-09-16 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Structural and Histone Binding Ability Characterizations of Human PWWP Domains. Plos One, 6, 2011
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4ZRD
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![BU of 4zrd by Molmil](/molmil-images/mine/4zrd) | Crystal structure of SMG1 F278N mutant | 分子名称: | GLYCEROL, LIP1, secretory lipase (Family 3), ... | 著者 | Xu, J, Xu, H, Hou, S, Liu, J. | 登録日 | 2015-05-12 | 公開日 | 2015-09-23 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of product-bound SMG1 lipase: active site gating implications. Febs J., 282, 2015
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4Z0X
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6LBC
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![BU of 6lbc by Molmil](/molmil-images/mine/6lbc) | shrimp ferritin-T158R | 分子名称: | FE (III) ION, Ferritin | 著者 | Zhao, G, Chen, H, Zhang, T. | 登録日 | 2019-11-14 | 公開日 | 2020-11-25 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.801 Å) | 主引用文献 | Construction of thermally robust and porous shrimp ferritin crystalline for molecular encapsulation through intermolecular arginine-arginine attractions. Food Chem, 349, 2021
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4ZRE
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![BU of 4zre by Molmil](/molmil-images/mine/4zre) | Crystal structure of SMG1 F278D mutant | 分子名称: | CHLORIDE ION, LIP1, secretory lipase (Family 3), ... | 著者 | Xu, J, Xu, H, Hou, S, Liu, J. | 登録日 | 2015-05-12 | 公開日 | 2015-09-23 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of product-bound SMG1 lipase: active site gating implications. Febs J., 282, 2015
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6L5L
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![BU of 6l5l by Molmil](/molmil-images/mine/6l5l) | Crystal structure of human DEAD-box RNA helicase DDX21 at apo state | 分子名称: | MAGNESIUM ION, Nucleolar RNA helicase 2 | 著者 | Chen, Z.J, Hu, X.J, Zhou, Z, Li, J.X. | 登録日 | 2019-10-24 | 公開日 | 2020-06-17 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation. Adv Sci, 7, 2020
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6L5D
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6L5N
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![BU of 6l5n by Molmil](/molmil-images/mine/6l5n) | Crystal structure of human DEAD-box RNA helicase DDX21 at post-unwound state | 分子名称: | MAGNESIUM ION, Nucleolar RNA helicase 2, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Chen, Z.J, Hu, X.J, Zhou, Z, Li, J.X. | 登録日 | 2019-10-24 | 公開日 | 2020-06-17 | 最終更新日 | 2020-08-12 | 実験手法 | X-RAY DIFFRACTION (2.242 Å) | 主引用文献 | Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation. Adv Sci, 7, 2020
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6L5O
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![BU of 6l5o by Molmil](/molmil-images/mine/6l5o) | Crystal structure of human DEAD-box RNA helicase DDX21 at post-hydrolysis state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | 著者 | Chen, Z.J, Hu, X.J, Zhou, Z, Li, J.X. | 登録日 | 2019-10-24 | 公開日 | 2020-06-17 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation. Adv Sci, 7, 2020
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6LBD
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![BU of 6lbd by Molmil](/molmil-images/mine/6lbd) | shrimp ferritin T158R G159R | 分子名称: | CHLORIDE ION, FE (III) ION, Ferritin | 著者 | Zhao, G, Chen, H. | 登録日 | 2019-11-14 | 公開日 | 2020-11-25 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.386 Å) | 主引用文献 | Construction of thermally robust and porous shrimp ferritin crystalline for molecular encapsulation through intermolecular arginine-arginine attractions. Food Chem, 349, 2021
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6M11
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![BU of 6m11 by Molmil](/molmil-images/mine/6m11) | Crystal structure of Rnase L in complex with Sunitinib | 分子名称: | 5'-O-MONOPHOSPHORYLADENYLYL(2'->5')ADENYLYL(2'->5')ADENOSINE, N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carbo xamide, PHOSPHATE ION, ... | 著者 | Tang, J, Huang, H. | 登録日 | 2020-02-24 | 公開日 | 2020-09-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | 主引用文献 | Sunitinib inhibits RNase L by destabilizing its active dimer conformation. Biochem.J., 477, 2020
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