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5CQY
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E. coli MazF mutant E24A in complex with MazE residues 68-82 form II
分子名称: Antitoxin MazE, Endoribonuclease MazF
著者Zorzini, V, Loris, R.
登録日2015-07-22
公開日2016-04-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.481 Å)
主引用文献Substrate Recognition and Activity Regulation of the Escherichia coli mRNA Endonuclease MazF.
J.Biol.Chem., 291, 2016
5CW7
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Crystal structure of the PaaA2-ParE2 antitoxin-toxin complex
分子名称: GLYCEROL, PAAA2, Plasmid stabilization protein ParE
著者Sterckx, Y.G.-J, Loris, R.
登録日2015-07-27
公開日2016-06-01
実験手法X-RAY DIFFRACTION (2.827 Å)
主引用文献A unique hetero-hexadecameric architecture displayed by the Escherichia coli O157 PaaA2-ParE2 antitoxin-toxin complex.
J.Mol.Biol., 428, 2016
1ZV5
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Crystal structure of the variable domain of the camelid heavy-chain antibody D2-L29 in complex with hen egg white lysozyme
分子名称: Lysozyme C, PHOSPHATE ION, immunoglobulin heavy chain antibody variable domain
著者De Genst, E, Silence, K, Decanniere, K, Conrath, K, Loris, R, Kinne, J, Muyldermans, S, Wyns, L.
登録日2005-06-01
公開日2006-04-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies.
Proc.Natl.Acad.Sci.Usa, 103, 2006
1XFP
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Crystal structure of the CDR2 germline reversion mutant of cAb-Lys3 in complex with hen egg white lysozyme
分子名称: FORMIC ACID, Lysozyme C, heavy chain antibody
著者De Genst, E, Handelberg, F, Van Meirhaeghe, A, Vynck, S, Loris, R, Wyns, L, Muyldermans, S.
登録日2004-09-15
公開日2004-09-28
最終更新日2013-02-06
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Chemical Basis for the Affinity Maturation of a Camel Single Domain Antibody
J.Biol.Chem., 279, 2004
1BVI
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RIBONUCLEASE T1 (WILDTYPE) COMPLEXED WITH 2'GMP
分子名称: CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, PROTEIN (RIBONUCLEASE T1)
著者Langhorst, U, Loris, R, Denisov, V.P, Doumen, J, Roose, P, Maes, D, Halle, B, Steyaert, J.
登録日1998-09-15
公開日1998-09-23
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Dissection of the structural and functional role of a conserved hydration site in RNase T1.
Protein Sci., 8, 1999
1YC8
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cAbAn33- Y37V/E44G/R45L triple mutant
分子名称: anti-VSG immunoglobulin heavy chain variable domain cAbAn33
著者Conrath, K, Vincke, C, Stijlemans, B, Schymkowitz, J, Wyns, L, Muyldermans, S, Loris, R.
登録日2004-12-22
公開日2005-06-14
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Antigen Binding and Solubility Effects upon the Veneering of a Camel VHH in Framework-2 to Mimic a VH.
J.Mol.Biol., 350, 2005
1YC7
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cAbAn33 VHH fragment against VSG
分子名称: SULFATE ION, anti-VSG immunoglobulin heavy chain variable domain cAbAn33
著者Conrath, K, Vincke, C, Stijlemans, B, Schymkowitz, J, Wyns, L, Muyldermans, S, Loris, R.
登録日2004-12-22
公開日2005-06-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Antigen Binding and Solubility Effects upon the Veneering of a Camel VHH in Framework-2 to Mimic a VH.
J.Mol.Biol., 350, 2005
1ZPL
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E. coli F17a-G lectin domain complex with GlcNAc(beta1-O)Me
分子名称: F17a-G, methyl 2-acetamido-2-deoxy-beta-D-glucopyranoside
著者Buts, L, Wellens, A, Van Molle, I, Wyns, L, Loris, R, Lahmann, M, Oscarson, S, De Greve, H, Bouckaert, J.
登録日2005-05-17
公開日2006-05-23
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Impact of natural variation in bacterial F17G adhesins on crystallization behaviour.
Acta Crystallogr.,Sect.D, 61, 2005
1APN
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THE CRYSTALLOGRAPHIC STRUCTURE OF METAL-FREE CONCANAVALIN A AT 2.5 ANGSTROMS RESOLUTION
分子名称: CONCANAVALIN A
著者Bouckaert, J, Loris, R, Poortmans, F, Wyns, L.
登録日1995-07-28
公開日1996-04-03
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystallographic structure of metal-free concanavalin A at 2.5 A resolution.
Proteins, 23, 1995
1ZK5
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Escherichia coli F17fG lectin domain complex with N-acetylglucosamine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, F17G adhesin subunit
著者Buts, L, Wellens, A, Van Molle, I, De Genst, E, Wyns, L, Loris, R, Lahmann, M, Oscarson, S, De Greve, H, Bouckaert, J.
登録日2005-05-02
公開日2006-05-02
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Impact of natural variation in bacterial F17G adhesins on crystallization behaviour.
Acta Crystallogr.,Sect.D, 61, 2005
1YZZ
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Humanized caban33 at room temperature
分子名称: anti-VSG immunoglobulin heavy chain variable domain cAbAn33
著者Conrath, K, Vincke, C, Stijlemans, B, Schymkowitz, J, Decanniere, K, Muyldermans, S, Loris, R.
登録日2005-03-01
公開日2005-06-14
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Antigen binding and solubility effects upon the veneering of a camel VHH in framework-2 to mimic a VH.
J.Mol.Biol., 350, 2005
1ZMY
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cAbBCII-10 VHH framework with CDR loops of cAbLys3 grafted on it and in complex with hen egg white lysozyme
分子名称: Antibody cabbcII-10:lys3, Lysozyme C
著者Saerens, D, Pellis, M, Loris, R, Pardon, E, Dumoulin, M, Matagne, A, Wyns, L, Muyldermans, S, Conrath, K.
登録日2005-05-11
公開日2005-10-04
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Identification of a universal VHH framework to graft non-canonical antigen-binding loops of camel single-domain antibodies
J.Mol.Biol., 352, 2005
1X75
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CcdB:GyrA14 complex
分子名称: Cytotoxic protein ccdB, DNA gyrase subunit A
著者Dao-Thi, M.H, Van Melderen, L, De Genst, E, Wyns, L, Loris, R.
登録日2004-08-13
公開日2005-05-17
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Molecular Basis of Gyrase Poisoning by the Addiction Toxin CcdB
J.Mol.Biol., 348, 2005
1ZVH
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BU of 1zvh by Molmil
Crystal structure of the VHH domain D2-L24 in complex with hen egg white lysozyme
分子名称: Immunoglobulin heavy chain antibody variable domain, Lysozyme C
著者De Genst, E, Silence, K, Decanniere, K, Conrath, K, Loris, R, Kinne, J, Muyldermans, S, Wyns, L.
登録日2005-06-02
公開日2006-04-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies.
Proc.Natl.Acad.Sci.Usa, 103, 2006
1ZVY
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Crystal structure of the VHH D3-L11 in complex with hen egg white lysozyme
分子名称: GLYCEROL, Immunoglobulin heavy chain antibody variable domain, Lysozyme C, ...
著者De Genst, E, Silence, K, Decanniere, K, Conrath, K, Loris, R, Kinne, J, Muyldermans, S, Wyns, L.
登録日2005-06-03
公開日2006-04-04
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies.
Proc.Natl.Acad.Sci.Usa, 103, 2006
1I0V
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Ribonuclease T1 in complex with 2'GMP (form I crystal)
分子名称: CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, GUANYL-SPECIFIC RIBONUCLEASE T1
著者De Swarte, J, De Vos, S, Langhorst, U, Steyaert, J, Loris, R.
登録日2001-01-30
公開日2001-02-14
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.234 Å)
主引用文献The contribution of metal ions to the conformational stability of ribonuclease T1: crystal versus solution.
Eur.J.Biochem., 268, 2001
1I0X
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RIBONUCLEASE T1 IN COMPLEX WITH 2'GMP (FORM II CRYSTAL)
分子名称: CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, GUANYL-SPECIFIC RIBONUCLEASE T1
著者De Swarte, J, De Vos, S, Langhorst, U, Steyaert, J, Loris, R.
登録日2001-01-30
公開日2001-02-14
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献The contribution of metal ions to the conformational stability of ribonuclease T1: crystal versus solution.
Eur.J.Biochem., 268, 2001
1HZ1
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RIBONUCLEASE T1 V16A MUTANT IN COMPLEX WITH MG2+
分子名称: GUANOSINE-2'-MONOPHOSPHATE, MAGNESIUM ION, RIBONUCLEASE T1
著者De Swarte, J, De Vos, S, Langhorst, U, Steyaert, J, Loris, R.
登録日2001-01-23
公開日2001-01-31
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The contribution of metal ions to the conformational stability of ribonuclease T1: crystal versus solution.
Eur.J.Biochem., 268, 2001
1I2E
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Ribonuclease T1 V16A mutant, form I
分子名称: CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, GUANYL-SPECIFIC RIBONUCLEASE T1
著者De Vos, S, Backmann, J, Steyaert, J, Loris, R.
登録日2001-02-09
公開日2001-03-07
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Hydrophobic core manipulations in ribonuclease T1
Biochemistry, 40, 2001
2MRN
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Structure of truncated EcMazE
分子名称: Antitoxin MazE
著者Zorzini, V, Buts, L, Loris, R, van Nuland, N.A.J.
登録日2014-07-12
公開日2015-02-04
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Escherichia coli antitoxin MazE as transcription factor: insights into MazE-DNA binding.
Nucleic Acids Res., 43, 2015
2O7K
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S. aureus thioredoxin
分子名称: Thioredoxin
著者Roos, G, Garcia-Pino, A, Van Belle, K, Brosens, E, Wahni, K, Vandenbussche, G, Wyns, L, Loris, R, Messens, J.
登録日2006-12-11
公開日2007-07-24
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The conserved active site proline determines the reducing power of Staphylococcus aureus thioredoxin
J.Mol.Biol., 368, 2007
2O89
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S. aureus thioredoxin P31T/C32S mutant
分子名称: Thioredoxin
著者Roos, G, Loris, R, Messens, J.
登録日2006-12-12
公開日2007-07-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献The conserved active site proline determines the reducing power of Staphylococcus aureus thioredoxin
J.Mol.Biol., 368, 2007
1I3I
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Ribonuclease T1 V78T mutant
分子名称: CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, GUANYL-SPECIFIC RIBONUCLEASE T1
著者De Vos, S, Backmann, J, Steyaert, J, Loris, R.
登録日2001-02-15
公開日2001-03-07
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Hydrophobic core manipulations in ribonuclease T1
Biochemistry, 40, 2001
2O85
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S. Aureus thioredoxin P31T mutant
分子名称: Thioredoxin
著者Roos, G, Loris, R, Messens, J.
登録日2006-12-12
公開日2007-07-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The conserved active site proline determines the reducing power of Staphylococcus aureus thioredoxin
J.Mol.Biol., 368, 2007
2MRU
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Structure of truncated EcMazE-DNA complex
分子名称: Antitoxin MazE, DNA (5'-D(*CP*GP*TP*GP*AP*TP*AP*TP*AP*TP*AP*GP*TP*GP*C)-3'), DNA (5'-D(P*GP*CP*AP*CP*TP*AP*TP*AP*TP*AP*TP*CP*AP*CP*G)-3')
著者Zorzini, V, Buts, L, Loris, R, van Nuland, N.
登録日2014-07-15
公開日2015-02-04
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Escherichia coli antitoxin MazE as transcription factor: insights into MazE-DNA binding.
Nucleic Acids Res., 43, 2015

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