1YZZ
 
 | | Humanized caban33 at room temperature | | 分子名称: | anti-VSG immunoglobulin heavy chain variable domain cAbAn33 | | 著者 | Conrath, K, Vincke, C, Stijlemans, B, Schymkowitz, J, Decanniere, K, Muyldermans, S, Loris, R. | | 登録日 | 2005-03-01 | | 公開日 | 2005-06-14 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Antigen binding and solubility effects upon the veneering of a camel VHH in framework-2 to mimic a VH.
J.Mol.Biol., 350, 2005
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1ZMY
 | | cAbBCII-10 VHH framework with CDR loops of cAbLys3 grafted on it and in complex with hen egg white lysozyme | | 分子名称: | Antibody cabbcII-10:lys3, Lysozyme C | | 著者 | Saerens, D, Pellis, M, Loris, R, Pardon, E, Dumoulin, M, Matagne, A, Wyns, L, Muyldermans, S, Conrath, K. | | 登録日 | 2005-05-11 | | 公開日 | 2005-10-04 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Identification of a universal VHH framework to graft non-canonical antigen-binding loops of camel single-domain antibodies
J.Mol.Biol., 352, 2005
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1ZVH
 | | Crystal structure of the VHH domain D2-L24 in complex with hen egg white lysozyme | | 分子名称: | Immunoglobulin heavy chain antibody variable domain, Lysozyme C | | 著者 | De Genst, E, Silence, K, Decanniere, K, Conrath, K, Loris, R, Kinne, J, Muyldermans, S, Wyns, L. | | 登録日 | 2005-06-02 | | 公開日 | 2006-04-04 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies.
Proc.Natl.Acad.Sci.Usa, 103, 2006
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1ZVY
 | | Crystal structure of the VHH D3-L11 in complex with hen egg white lysozyme | | 分子名称: | GLYCEROL, Immunoglobulin heavy chain antibody variable domain, Lysozyme C, ... | | 著者 | De Genst, E, Silence, K, Decanniere, K, Conrath, K, Loris, R, Kinne, J, Muyldermans, S, Wyns, L. | | 登録日 | 2005-06-03 | | 公開日 | 2006-04-04 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies.
Proc.Natl.Acad.Sci.Usa, 103, 2006
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1YC8
 | | cAbAn33- Y37V/E44G/R45L triple mutant | | 分子名称: | anti-VSG immunoglobulin heavy chain variable domain cAbAn33 | | 著者 | Conrath, K, Vincke, C, Stijlemans, B, Schymkowitz, J, Wyns, L, Muyldermans, S, Loris, R. | | 登録日 | 2004-12-22 | | 公開日 | 2005-06-14 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Antigen Binding and Solubility Effects upon the Veneering of a Camel VHH in Framework-2 to Mimic a VH.
J.Mol.Biol., 350, 2005
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1YC7
 | | cAbAn33 VHH fragment against VSG | | 分子名称: | SULFATE ION, anti-VSG immunoglobulin heavy chain variable domain cAbAn33 | | 著者 | Conrath, K, Vincke, C, Stijlemans, B, Schymkowitz, J, Wyns, L, Muyldermans, S, Loris, R. | | 登録日 | 2004-12-22 | | 公開日 | 2005-06-14 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Antigen Binding and Solubility Effects upon the Veneering of a Camel VHH in Framework-2 to Mimic a VH.
J.Mol.Biol., 350, 2005
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2AR6
 | | Pterocarpus angolensis Lectin (PAL) In Complex With The Pentasaccharide M592 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose, CALCIUM ION, ... | | 著者 | Buts, L, Garcia-Pino, A, Imberty, A, Amiot, N, Boons, G.J, Beeckmans, S, Versees, W, Wyns, L, Loris, R. | | 登録日 | 2005-08-19 | | 公開日 | 2006-08-01 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural basis for the recognition of complex-type biantennary oligosaccharides by Pterocarpus angolensis lectin.
Febs J., 273, 2006
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2HOH
 | | RIBONUCLEASE T1 (N9A MUTANT) COMPLEXED WITH 2'GMP | | 分子名称: | CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, PHOSPHATE ION, ... | | 著者 | Langhorst, U, Loris, R, Denisov, V.P, Doumen, J, Roose, P, Maes, D, Halle, B, Steyaert, J. | | 登録日 | 1998-09-14 | | 公開日 | 1998-09-23 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Dissection of the structural and functional role of a conserved hydration site in RNase T1.
Protein Sci., 8, 1999
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2GME
 | | Metal-free (apo) P. angolensis seed lectin | | 分子名称: | SULFATE ION, lectin | | 著者 | Garcia-Pino, A, Buts, L, Wyns, L, Loris, R. | | 登録日 | 2006-04-06 | | 公開日 | 2006-07-25 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Interplay Between Metal Binding and cis/trans Isomerization in Legume Lectins: Structural and Thermodynamic Study of P. angolensis Lectin.
J.Mol.Biol., 361, 2006
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2GNM
 | | P. angolensis lectin (PAL) treated with EDTA for 39 hours | | 分子名称: | CALCIUM ION, MANGANESE (II) ION, alpha-D-mannopyranose, ... | | 著者 | Garcia-Pino, A, Buts, L, Wyns, L, Loris, R. | | 登録日 | 2006-04-10 | | 公開日 | 2006-07-25 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Interplay Between Metal Binding and cis/trans Isomerization in Legume Lectins: Structural and Thermodynamic Study of P. angolensis Lectin.
J.Mol.Biol., 361, 2006
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2GMM
 | | Metal-free (apo) P. angolensis seed lectin in complex with Man-alpha(1-2)Man | | 分子名称: | SULFATE ION, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose, lectin | | 著者 | Garcia-Pino, A, Buts, L, Wyns, L, Loris, R. | | 登録日 | 2006-04-07 | | 公開日 | 2006-07-25 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Interplay Between Metal Binding and cis/trans Isomerization in Legume Lectins: Structural and Thermodynamic Study of P. angolensis Lectin.
J.Mol.Biol., 361, 2006
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2GND
 | | One hour EDTA treatment, P. angolensis lectin | | 分子名称: | CALCIUM ION, MANGANESE (II) ION, alpha-D-mannopyranose, ... | | 著者 | Garcia-Pino, A, Buts, L, Wyns, L, Loris, R. | | 登録日 | 2006-04-10 | | 公開日 | 2006-07-25 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Interplay Between Metal Binding and cis/trans Isomerization in Legume Lectins: Structural and Thermodynamic Study of P. angolensis Lectin.
J.Mol.Biol., 361, 2006
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2GNB
 | | EDTA-treated (2 weeks) P. angolensis lectin | | 分子名称: | alpha-D-mannopyranose, lectin | | 著者 | Garcia-Pino, A, Buts, L, Wyns, L, Loris, R. | | 登録日 | 2006-04-09 | | 公開日 | 2006-07-25 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | | 主引用文献 | Interplay Between Metal Binding and cis/trans Isomerization in Legume Lectins: Structural and Thermodynamic Study of P. angolensis Lectin.
J.Mol.Biol., 361, 2006
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2GN3
 | | Metal-free (apo-PAL) in complex with alpha-D-Met-Man | | 分子名称: | SULFATE ION, alpha-D-mannopyranose, lectin, ... | | 著者 | Garcia-Pino, A, Buts, L, Wyns, L, Loris, R. | | 登録日 | 2006-04-09 | | 公開日 | 2006-07-25 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Interplay Between Metal Binding and cis/trans Isomerization in Legume Lectins: Structural and Thermodynamic Study of P. angolensis Lectin.
J.Mol.Biol., 361, 2006
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2GMP
 | | Metal-free (apo) P. angolensis seed lectin in complex with GlcNAC-beta(1-2)Man | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose, SULFATE ION, lectin | | 著者 | Garcia-Pino, A, Buts, L, Wyns, L, Loris, R. | | 登録日 | 2006-04-07 | | 公開日 | 2006-07-25 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Interplay Between Metal Binding and cis/trans Isomerization in Legume Lectins: Structural and Thermodynamic Study of P. angolensis Lectin.
J.Mol.Biol., 361, 2006
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2GNT
 | | EDTA treated P. angolensis lectin (PAL) remetallized with calcium (1 hour treatment) | | 分子名称: | CALCIUM ION, lectin | | 著者 | Garcia-Pino, A, Buts, L, Wyns, L, Loris, R. | | 登録日 | 2006-04-11 | | 公開日 | 2006-07-25 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Interplay Between Metal Binding and cis/trans Isomerization in Legume Lectins: Structural and Thermodynamic Study of P. angolensis Lectin.
J.Mol.Biol., 361, 2006
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2GN7
 | | Metal-free (apo) P. angolensis seed lectin in complex with Man-alpha(1-3)Man-alpha(1-6)Man | | 分子名称: | alpha-D-mannopyranose, beta-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose, lectin | | 著者 | Garcia-Pino, A, Buts, L, Wyns, L, Loris, R. | | 登録日 | 2006-04-09 | | 公開日 | 2006-07-25 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Interplay Between Metal Binding and cis/trans Isomerization in Legume Lectins: Structural and Thermodynamic Study of P. angolensis Lectin.
J.Mol.Biol., 361, 2006
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1I0V
 | | Ribonuclease T1 in complex with 2'GMP (form I crystal) | | 分子名称: | CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, GUANYL-SPECIFIC RIBONUCLEASE T1 | | 著者 | De Swarte, J, De Vos, S, Langhorst, U, Steyaert, J, Loris, R. | | 登録日 | 2001-01-30 | | 公開日 | 2001-02-14 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (1.234 Å) | | 主引用文献 | The contribution of metal ions to the conformational stability of ribonuclease T1: crystal versus solution.
Eur.J.Biochem., 268, 2001
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1I0X
 | | RIBONUCLEASE T1 IN COMPLEX WITH 2'GMP (FORM II CRYSTAL) | | 分子名称: | CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, GUANYL-SPECIFIC RIBONUCLEASE T1 | | 著者 | De Swarte, J, De Vos, S, Langhorst, U, Steyaert, J, Loris, R. | | 登録日 | 2001-01-30 | | 公開日 | 2001-02-14 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | The contribution of metal ions to the conformational stability of ribonuclease T1: crystal versus solution.
Eur.J.Biochem., 268, 2001
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1HZ1
 | | RIBONUCLEASE T1 V16A MUTANT IN COMPLEX WITH MG2+ | | 分子名称: | GUANOSINE-2'-MONOPHOSPHATE, MAGNESIUM ION, RIBONUCLEASE T1 | | 著者 | De Swarte, J, De Vos, S, Langhorst, U, Steyaert, J, Loris, R. | | 登録日 | 2001-01-23 | | 公開日 | 2001-01-31 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The contribution of metal ions to the conformational stability of ribonuclease T1: crystal versus solution.
Eur.J.Biochem., 268, 2001
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1I2G
 | | Ribonuclease T1 V16T mutant | | 分子名称: | CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, GUANYL-SPECIFIC RIBONUCLEASE T1 | | 著者 | De Vos, S, Backmann, J, Steyaert, J, Loris, R. | | 登録日 | 2001-02-09 | | 公開日 | 2001-03-07 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Hydrophobic core manipulations in ribonuclease T1
Biochemistry, 40, 2001
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1I3I
 | | Ribonuclease T1 V78T mutant | | 分子名称: | CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, GUANYL-SPECIFIC RIBONUCLEASE T1 | | 著者 | De Vos, S, Backmann, J, Steyaert, J, Loris, R. | | 登録日 | 2001-02-15 | | 公開日 | 2001-03-07 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Hydrophobic core manipulations in ribonuclease T1
Biochemistry, 40, 2001
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1I2F
 | | Ribonuclease T1 V16A mutant, form II | | 分子名称: | CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, GUANYL-SPECIFIC RIBONUCLEASE T1 | | 著者 | De Vos, S, Backmann, J, Steyaert, J, Loris, R. | | 登録日 | 2001-02-09 | | 公開日 | 2001-03-07 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Hydrophobic core manipulations in ribonuclease T1
Biochemistry, 40, 2001
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1I3F
 | | Ribonuclease T1 V89S mutant | | 分子名称: | CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, GUANYL-SPECIFIC RIBONUCLEASE T1 | | 著者 | De Vos, S, Backmann, J, Steyaert, J, Loris, R. | | 登録日 | 2001-02-15 | | 公開日 | 2001-03-07 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Hydrophobic core manipulations in ribonuclease T1
Biochemistry, 40, 2001
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1LU2
 | | DOLICHOS BIFLORUS SEED LECTIN IN COMPLEX WITH THE BLOOD GROUP A TRISACCHARIDE | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, CALCIUM ION, LECTIN, ... | | 著者 | Hamelryck, T.W, Loris, R, Bouckaert, J, Strecker, G, Imberty, A, Fernandez, E, Wyns, L, Etzler, M.E. | | 登録日 | 1998-07-30 | | 公開日 | 1998-12-09 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Carbohydrate binding, quaternary structure and a novel hydrophobic binding site in two legume lectin oligomers from Dolichos biflorus.
J.Mol.Biol., 286, 1999
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