5Z4M
 
 | | Structure of TailorD343A with bound UTP and Mg | | 分子名称: | MAGNESIUM ION, Terminal uridylyltransferase Tailor, URIDINE 5'-TRIPHOSPHATE | | 著者 | Cheng, L, Li, F, Jiang, Y, Yu, H, Xie, C, Shi, Y, Gong, Q. | | 登録日 | 2018-01-11 | | 公開日 | 2018-10-31 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Structural insights into a unique preference for 3' terminal guanine of mirtron in Drosophila TUTase tailor.
Nucleic Acids Res., 47, 2019
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5Z4C
 | | Crystal structure of Tailor | | 分子名称: | Terminal uridylyltransferase Tailor | | 著者 | Cheng, L, Li, F, Jiang, Y, Yu, H, Xie, C, Shi, Y, Gong, Q. | | 登録日 | 2018-01-10 | | 公開日 | 2018-10-31 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structural insights into a unique preference for 3' terminal guanine of mirtron in Drosophila TUTase tailor.
Nucleic Acids Res., 47, 2019
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5YYX
 | | Crystal Structure of the MEK1 FHA domain | | 分子名称: | Meiosis-specific serine/threonine-protein kinase MEK1 | | 著者 | Xie, C, Li, F, Jiang, Y, Wu, J, Shi, Y. | | 登録日 | 2017-12-11 | | 公開日 | 2018-10-10 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.684 Å) | | 主引用文献 | Structural insights into the recognition of phosphorylated Hop1 by Mek1
Acta Crystallogr D Struct Biol, 74, 2018
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5Z4J
 | | Structure of Tailor in complex with U4 RNA | | 分子名称: | RNA (5'-R(*UP*UP*UP*U)-3'), Terminal uridylyltransferase Tailor | | 著者 | Cheng, L, Li, F, Jiang, Y, Yu, H, Xie, C, Shi, Y, Gong, Q. | | 登録日 | 2018-01-11 | | 公開日 | 2018-10-31 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Structural insights into a unique preference for 3' terminal guanine of mirtron in Drosophila TUTase tailor.
Nucleic Acids Res., 47, 2019
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5Z4A
 | | Structure of Tailor in complex with AGU RNA | | 分子名称: | RNA (5'-R(*AP*GP*U)-3'), Terminal uridylyltransferase Tailor | | 著者 | Cheng, L, Li, F, Jiang, Y, Yu, H, Xie, C, Shi, Y, Gong, Q. | | 登録日 | 2018-01-10 | | 公開日 | 2018-10-31 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.637 Å) | | 主引用文献 | Structural insights into a unique preference for 3' terminal guanine of mirtron in Drosophila TUTase tailor.
Nucleic Acids Res., 47, 2019
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6AAX
 | | Crystal structure of TFB1M and h45 with SAM in homo sapiens | | 分子名称: | DI(HYDROXYETHYL)ETHER, Dimethyladenosine transferase 1, mitochondrial, ... | | 著者 | Liu, X, Shen, S, Wu, P, Li, F, Gong, Q, Wu, J, Zhang, H, Shi, Y. | | 登録日 | 2018-07-19 | | 公開日 | 2019-06-05 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.994 Å) | | 主引用文献 | Structural insights into dimethylation of 12S rRNA by TFB1M: indispensable role in translation of mitochondrial genes and mitochondrial function.
Nucleic Acids Res., 47, 2019
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4NAQ
 | | Crystal structure of porcine aminopeptidase-N complexed with poly-alanine | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Aminopeptidase N, ... | | 著者 | Chen, L, Lin, Y.L, Peng, G, Li, F. | | 登録日 | 2013-10-22 | | 公開日 | 2013-12-04 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis for multifunctional roles of mammalian aminopeptidase N.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4NN2
 | | Protein Crystal Structure of Human Borjeson-Forssman-Lehmann Syndrome Associated Protein PHF6 | | 分子名称: | GLYCEROL, PHD finger protein 6, ZINC ION | | 著者 | Liu, Z, Li, F, Zhang, J, Mei, Y, Wu, J, Shi, Y. | | 登録日 | 2013-11-16 | | 公開日 | 2014-02-26 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.472 Å) | | 主引用文献 | Crystal Structure of the second extended PHD domain of human PHF6 protein
J.Biol.Chem., 2014
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4NVQ
 | | Human G9a in Complex with Inhibitor A-366 | | 分子名称: | 5'-methoxy-6'-[3-(pyrrolidin-1-yl)propoxy]spiro[cyclobutane-1,3'-indol]-2'-amine, Histone-lysine N-methyltransferase EHMT2, S-ADENOSYL-L-HOMOCYSTEINE, ... | | 著者 | Sweis, R.F, Pliushchev, M, Brown, P.J, Guo, J, Li, F, Maag, D, Petros, A.M, Soni, N.B, Tse, C, Vedadi, M, Michaelides, M.R, Chiang, G.G, Pappano, W.N. | | 登録日 | 2013-12-05 | | 公開日 | 2014-01-15 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Discovery and development of potent and selective inhibitors of histone methyltransferase g9a.
ACS Med Chem Lett, 5, 2014
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4NZ8
 | | Crystal structure of porcine aminopeptidase-N complexed with cleaved poly-alanine | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Aminopeptidase N, ... | | 著者 | Chen, L, Lin, Y.L, Peng, G, Li, F. | | 登録日 | 2013-12-11 | | 公開日 | 2013-12-25 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural basis for multifunctional roles of mammalian aminopeptidase N.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4OU3
 | | Crystal structure of porcine aminopeptidase N complexed with CNGRCG tumor-homing peptide | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Aminopeptidase N, ... | | 著者 | Liu, C, Yang, Y, Chen, L, Lin, Y.-L, Li, F. | | 登録日 | 2014-02-14 | | 公開日 | 2014-11-05 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | A Unified Mechanism for Aminopeptidase N-based Tumor Cell Motility and Tumor-homing Therapy.
J.Biol.Chem., 289, 2014
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5GJU
 | | DEAD-box RNA helicase | | 分子名称: | ADENOSINE MONOPHOSPHATE, ATP-dependent RNA helicase DeaD | | 著者 | Xu, L, Li, F, Wang, L, Shi, Y. | | 登録日 | 2016-07-02 | | 公開日 | 2017-05-31 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Insights into the Structure of Dimeric RNA Helicase CsdA and Indispensable Role of Its C-Terminal Regions.
Structure, 25, 2017
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5GI4
 | | DEAD-box RNA helicase | | 分子名称: | ATP-dependent RNA helicase DeaD | | 著者 | Xu, L, Wang, L, Li, F, Wu, L, Shi, Y. | | 登録日 | 2016-06-22 | | 公開日 | 2017-05-31 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.244 Å) | | 主引用文献 | Insights into the Structure of Dimeric RNA Helicase CsdA and Indispensable Role of Its C-Terminal Regions.
Structure, 25, 2017
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5GMV
 | | LC3B-FUNDC1 complex | | 分子名称: | Microtubule-associated proteins 1A/1B light chain 3B, Peptide from FUN14 domain-containing protein 1 | | 著者 | Lv, M, Wang, C, Li, F. | | 登録日 | 2016-07-17 | | 公開日 | 2017-03-08 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structural insights into the recognition of phosphorylated FUNDC1 by LC3B in mitophagy
Protein Cell, 8, 2017
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4HOM
 | | Crystal structure of porcine aminopeptidase-N complexed with substance P | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Chen, L, Lin, Y.L, Peng, G, Li, F. | | 登録日 | 2012-10-22 | | 公開日 | 2012-10-31 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural basis for multifunctional roles of mammalian aminopeptidase N.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4I9H
 | | Crystal structure of rabbit LDHA in complex with AP28669 | | 分子名称: | 1-O-[3-(5-carboxypyridin-2-yl)-5-fluorophenyl]-6-O-[4-({[(5-carboxypyridin-2-yl)sulfanyl]acetyl}amino)-2-chloro-5-methoxyphenyl]-D-mannitol, L-lactate dehydrogenase A chain | | 著者 | Zhou, T, Stephan, Z.G, Kohlmann, A, Li, F, Commodore, L, Greenfield, M.T, Shakespeare, W.C, Zhu, X, Dalgarno, D.C. | | 登録日 | 2012-12-05 | | 公開日 | 2013-01-23 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | Fragment growing and linking lead to novel nanomolar lactate dehydrogenase inhibitors.
J.Med.Chem., 56, 2013
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4I8X
 | | Crystal structure of rabbit LDHA in complex with AP27460 | | 分子名称: | 6-phenylpyridine-3-carboxylic acid, L-lactate dehydrogenase A chain | | 著者 | Zhou, T, Stephan, Z.G, Kohlmann, A, Li, F, Commodore, L, Greenfield, M.T, Zhu, X, Dalgarno, D.C. | | 登録日 | 2012-12-04 | | 公開日 | 2013-01-23 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | Fragment growing and linking lead to novel nanomolar lactate dehydrogenase inhibitors.
J.Med.Chem., 56, 2013
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4I9N
 | | Crystal structure of rabbit LDHA in complex with AP28161 and AP28122 | | 分子名称: | 6-({2-[(5-chloro-4-{[(2S)-2,3-dihydroxypropyl]oxy}-2-methoxyphenyl)amino]-2-oxoethyl}sulfanyl)pyridine-3-carboxylic acid, 6-[3-(carboxymethoxy)-5-fluorophenyl]pyridine-3-carboxylic acid, L-lactate dehydrogenase A chain | | 著者 | Zhou, T, Kohlmann, A, Stephan, Z.G, Li, F, Commodore, L, Greenfield, M.T, Shakespeare, W.C, Zhu, X, Dalgarno, D.C. | | 登録日 | 2012-12-05 | | 公開日 | 2013-01-23 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Fragment growing and linking lead to novel nanomolar lactate dehydrogenase inhibitors.
J.Med.Chem., 56, 2013
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4KXB
 | | Crystal structure of human aminopeptidase A complexed with bestatin | | 分子名称: | 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Yang, Y, Liu, C, Lin, Y.Y, Li, F. | | 登録日 | 2013-05-24 | | 公開日 | 2013-07-31 | | 最終更新日 | 2022-12-21 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural insights into central hypertension regulation by human aminopeptidase a.
J.Biol.Chem., 288, 2013
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4KX8
 | | Crystal structure of human aminopeptidase A complexed with amastatin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Yang, Y, Liu, C, Lin, Y.Y, Li, F. | | 登録日 | 2013-05-24 | | 公開日 | 2013-07-31 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural insights into central hypertension regulation by human aminopeptidase a.
J.Biol.Chem., 288, 2013
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4KX7
 | | Crystal structure of human aminopeptidase A | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Yang, Y, Liu, C, Lin, Y.Y, Li, F. | | 登録日 | 2013-05-24 | | 公開日 | 2013-07-31 | | 最終更新日 | 2022-12-21 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structural insights into central hypertension regulation by human aminopeptidase a.
J.Biol.Chem., 288, 2013
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4KXA
 | | Crystal structure of human aminopeptidase A complexed with aspartate and calcium | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Yang, Y, Liu, C, Lin, Y.Y, Li, F. | | 登録日 | 2013-05-24 | | 公開日 | 2013-07-31 | | 最終更新日 | 2022-12-21 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural insights into central hypertension regulation by human aminopeptidase a.
J.Biol.Chem., 288, 2013
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4KX9
 | | Crystal structure of human aminopeptidase A complexed with arginine | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Yang, Y, Liu, C, Lin, Y.Y, Li, F. | | 登録日 | 2013-05-24 | | 公開日 | 2013-07-31 | | 最終更新日 | 2022-12-21 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structural insights into central hypertension regulation by human aminopeptidase a.
J.Biol.Chem., 288, 2013
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4L3N
 | | Crystal structure of the receptor-binding domain from newly emerged Middle East respiratory syndrome coronavirus | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S protein | | 著者 | Chen, Y, Rajashankar, K.R, Yang, Y, Agnihothram, S.S, Liu, C, Lin, Y.-L, Baric, R.S, Li, F. | | 登録日 | 2013-06-06 | | 公開日 | 2013-07-31 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | Crystal structure of the receptor-binding domain from newly emerged middle East respiratory syndrome coronavirus.
J.Virol., 87, 2013
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4KXC
 | | Crystal structure of human aminopeptidase A complexed with glutamate | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Yang, Y, Liu, C, Lin, Y.Y, Li, F. | | 登録日 | 2013-05-25 | | 公開日 | 2013-07-31 | | 最終更新日 | 2022-12-21 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural insights into central hypertension regulation by human aminopeptidase a.
J.Biol.Chem., 288, 2013
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