7KL8
| Structure of F420 binding protein Rv1558 from Mycobacterium tuberculosis with F420 bound | 分子名称: | COENZYME F420, COENZYME F420-3, Deazaflavin-dependent nitroreductase, ... | 著者 | Lee, B.M, Tan, L.L, Jackson, C.J. | 登録日 | 2020-10-29 | 公開日 | 2021-03-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.469 Å) | 主引用文献 | Potency boost of a Mycobacterium tuberculosis dihydrofolate reductase inhibitor by multienzyme F 420 H 2 -dependent reduction. Proc.Natl.Acad.Sci.USA, 118, 2021
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7KW0
| Non-ribosomal didomain (stabilised glycine-PCP-C) acceptor bound state | 分子名称: | N-{2-[(2-aminoethyl)sulfanyl]ethyl}-N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alaninamide, PCP-C didomain | 著者 | Izore, T, Ho, Y.T.C, Kaczmarski, J.A, Gavriilidou, A, Chow, K.H, Steer, D, Goode, R.J.A, Schittenhelm, R.B, Tailhades, J, Tosin, M, Challis, G.L, Krenske, E.H, Ziemert, N, Jackson, C.J, Cryle, M.J. | 登録日 | 2020-11-29 | 公開日 | 2021-03-24 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity. Nat Commun, 12, 2021
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7KVW
| Non-ribosomal didomain (holo-PCP-C) acceptor bound state | 分子名称: | 4'-PHOSPHOPANTETHEINE, PCP-C didomain | 著者 | Izore, T, Ho, Y.T.C, Kaczmarski, J.A, Gavriilidou, A, Chow, K.H, Steer, D, Goode, R.J.A, Schittenhelm, R.B, Tailhades, J, Tosin, M, Challis, G.L, Krenske, E.H, Ziemert, N, Jackson, C.J, Cryle, M.J. | 登録日 | 2020-11-29 | 公開日 | 2021-03-24 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity. Nat Commun, 12, 2021
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7KW2
| Non-ribosomal didomain (holo-PCP-C) acceptor bound state, R2577G | 分子名称: | 4'-PHOSPHOPANTETHEINE, PCP-C didomain | 著者 | Izore, T, Ho, Y.T.C, Kaczmarski, J.A, Gavriilidou, A, Chow, K.H, Steer, D, Goode, R.J.A, Schittenhelm, R.B, Tailhades, J, Tosin, M, Challis, G.L, Krenske, E.H, Ziemert, N, Jackson, C.J, Cryle, M.J. | 登録日 | 2020-11-29 | 公開日 | 2021-03-24 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity. Nat Commun, 12, 2021
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7KW3
| Non Ribosomal PCP domain | 分子名称: | PCP domain, SULFATE ION | 著者 | Izore, T, Ho, Y.T.C, Kaczmarski, J.A, Gavriilidou, A, Chow, K.H, Steer, D, Goode, R.J.A, Schittenhelm, R.B, Tailhades, J, Tosin, M, Challis, G.L, Krenske, E.H, Ziemert, N, Jackson, C.J, Cryle, M.J. | 登録日 | 2020-11-29 | 公開日 | 2021-03-24 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity. Nat Commun, 12, 2021
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8CRU
| PETase Ancestral Sequence Reconstruction 008 | 分子名称: | CITRIC ACID, Poly(ethylene terephthalate) hydrolase | 著者 | Joho, Y, Royan, S, Caputo, A.T, Ardevol Grau, A, Jackson, C. | 登録日 | 2022-05-11 | 公開日 | 2022-09-21 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Ancestral Sequence Reconstruction Identifies Structural Changes Underlying the Evolution of Ideonella sakaiensis PETase and Variants with Improved Stability and Activity. Biochemistry, 62, 2023
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4N1C
| Structural evidence for antigen receptor evolution | 分子名称: | Lysozyme C, immunoglobulin variable light chain domain | 著者 | Langley, D.B, Rouet, R, Roome, B, Stock, D, Christ, D. | 登録日 | 2013-10-03 | 公開日 | 2014-10-29 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural reconstruction of protein ancestry. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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4N1E
| Structural evidence for antigen receptor evolution | 分子名称: | Lysozyme C, immunoglobulin variable light chain domain | 著者 | Langley, D.B, Rouet, R, Stock, D, Christ, D. | 登録日 | 2013-10-04 | 公開日 | 2014-10-29 | 最終更新日 | 2018-04-18 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | Structural reconstruction of protein ancestry. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6WUP
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7OQ6
| Crystal structure of cytochrome P450 Sas16 from Streptomyces asterosporus | 分子名称: | Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, THIOCYANATE ION | 著者 | Zhang, L, Zhang, S, Bechthold, A, Einsle, O. | 登録日 | 2021-06-02 | 公開日 | 2022-06-22 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | P450-mediated dehydrotyrosine formation during WS9326 biosynthesis proceeds via dehydrogenation of a specific acylated dipeptide substrate. Acta Pharm Sin B, 13, 2023
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8D4W
| Asymmetric ene-reduction of alpha,beta-unsaturated compounds using MSMEG_2850 | 分子名称: | Cell entry (Mce) related family protein, DI(HYDROXYETHYL)ETHER, GLYCEROL | 著者 | Kang, S.W, Frkic, R.L, Jackson, C. | 登録日 | 2022-06-02 | 公開日 | 2023-01-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Asymmetric Ene-Reduction of alpha , beta-Unsaturated Compounds by F 420 -Dependent Oxidoreductases A Enzymes from Mycobacterium smegmatis . Biochemistry, 62, 2023
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5IKX
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8BON
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5JQJ
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5K4M
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6N4A
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6NTB
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6UW1
| The crystal structure of FbiA from Mycobacterium Smegmatis, Fo bound form | 分子名称: | 1-deoxy-1-(8-hydroxy-2,4-dioxo-3,4-dihydropyrimido[4,5-b]quinolin-10(2H)-yl)-D-ribitol, CALCIUM ION, Phosphoenolpyruvate transferase | 著者 | Grinter, R, Gillett, D, Cordero, P.R.F, Greening, C. | 登録日 | 2019-11-04 | 公開日 | 2020-05-13 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.205 Å) | 主引用文献 | Cellular and Structural Basis of Synthesis of the Unique Intermediate Dehydro-F420-0 in Mycobacteria. mSystems, 5, 2020
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6UVX
| The crystal structure of FbiA from Mycobacterium Smegmatis, Apo state | 分子名称: | CALCIUM ION, Phosphoenolpyruvate transferase | 著者 | Grinter, R, Gillett, D, Cordero, P.R.F, Greening, C. | 登録日 | 2019-11-04 | 公開日 | 2020-05-13 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Cellular and Structural Basis of Synthesis of the Unique Intermediate Dehydro-F420-0 in Mycobacteria. mSystems, 5, 2020
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6UW5
| The crystal structure of FbiA from Mycobacterium smegmatis, GDP and Fo bound form | 分子名称: | 1-deoxy-1-(8-hydroxy-2,4-dioxo-3,4-dihydropyrimido[4,5-b]quinolin-10(2H)-yl)-D-ribitol, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Grinter, R, Gillett, D, Cordero, P.R.F, Greening, C. | 登録日 | 2019-11-04 | 公開日 | 2020-05-13 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Cellular and Structural Basis of Synthesis of the Unique Intermediate Dehydro-F420-0 in Mycobacteria. mSystems, 5, 2020
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6UW7
| The crystal structure of FbiA from Mycobacterium smegmatis, Dehydro-F420-0 bound form | 分子名称: | 2-[oxidanyl-[(2~{R},3~{S},4~{S})-2,3,4-tris(oxidanyl)-5-[2,4,8-tris(oxidanylidene)-1,9-dihydropyrimido[4,5-b]quinolin-10-yl]pentoxy]phosphoryl]oxyprop-2-enoic acid, CALCIUM ION, GLYCEROL, ... | 著者 | Grinter, R, Gillett, D, Cordero, P.R.F, Izore, T, Greening, C. | 登録日 | 2019-11-04 | 公開日 | 2020-05-13 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.342 Å) | 主引用文献 | Cellular and Structural Basis of Synthesis of the Unique Intermediate Dehydro-F420-0 in Mycobacteria. mSystems, 5, 2020
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6UW3
| The crystal structure of FbiA from Mycobacterium Smegmatis, GDP Bound form | 分子名称: | CALCIUM ION, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Grinter, R, Gillett, D, Cordero, P.R.F, Greening, C. | 登録日 | 2019-11-04 | 公開日 | 2020-05-13 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Cellular and Structural Basis of Synthesis of the Unique Intermediate Dehydro-F420-0 in Mycobacteria. mSystems, 5, 2020
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8FX6
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8FX7
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8G3J
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