5EH9

Indirect contributions of mutations underlie optimization of new enzyme function

Summary for 5EH9

• Entry DOI: 10.2210/pdb5eh9/pdb
• Related: 3DHB
• Descriptor: N-acyl homoserine lactonase AiiA, ZINC ION, GLYCEROL, ... (5 entities in total)
• Functional Keywords: n-acyl homoserine lactonase from bacillus thuringiensis, hydrolase
• Biological source: Bacillus thuringiensis subsp. kurstaki
• Total number of polymer chains: 1
• Total formula weight: 29432.14

Authors

Hong, N.-S.,Jackson, C.J.,Tokuriki, N.,Yang, G.,Baier, F. (deposition date: 2015-10-28, release date: 2016-09-07, Last modification date: 2023-09-27)

• Primary citation: Yang, G.,Hong, N.,Baier, F.,Jackson, C.J.,Tokuriki, N.; Conformational Tinkering Drives Evolution of a Promiscuous Activity through Indirect Mutational Effects.; Biochemistry, 55:4583-4593, 2016; PubMed: 27444875; DOI: 10.1021/acs.biochem.6b00561

Experimental method

X-RAY DIFFRACTION (1.29 Å)