8FX6

Non-ribosomal PCP-C didomain (amide stabilised leucine) acceptor bound state

Summary for 8FX6

Entry DOI	10.2210/pdb8fx6/pdb
Descriptor	PCP-C didomain, N-[2-({N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl]-L-leucinamide (3 entities in total)
Functional Keywords	nrps, c-domain, pcp-domain, biosynthetic protein
Biological source	Thermobifida fusca
Total number of polymer chains	2
Total formula weight	114487.25
Authors	Ho, Y.T.C.,Cryle, M.J. (deposition date: 2023-01-24, release date: 2023-06-21, Last modification date: 2023-12-27)
Primary citation	Ho, Y.T.C.,Kaczmarski, J.A.,Tailhades, J.,Izore, T.,Steer, D.L.,Schittenhelm, R.B.,Tosin, M.,Jackson, C.J.,Cryle, M.J. Not always an innocent bystander: the impact of stabilised phosphopantetheine moieties when studying nonribosomal peptide biosynthesis. Chem.Commun.(Camb.), 59:8234-8237, 2023 Cited by PubMed: 37310188 DOI: 10.1039/d3cc01578e PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation