5C8V
Lucilia cuprina alpha esterase 7: Gly137Asp
Summary for 5C8V
| Entry DOI | 10.2210/pdb5c8v/pdb |
| Descriptor | Carboxylic ester hydrolase (2 entities in total) |
| Functional Keywords | acetylcholinesterase, animals, australia, carboxylesterase, catalytic domain, diptera, drug resistance, genes, insect, insecticides, phosphorylation, protein structure, sheep, sheep diseases, substrate specificity, hydrolase |
| Biological source | Lucilia cuprina (Green bottle fly) |
| Total number of polymer chains | 1 |
| Total formula weight | 65486.80 |
| Authors | Correy, G.J.,Mabbitt, P.D.,Jackson, C.J. (deposition date: 2015-06-26, release date: 2016-03-09, Last modification date: 2023-09-27) |
| Primary citation | Mabbitt, P.D.,Correy, G.J.,Meirelles, T.,Fraser, N.J.,Coote, M.L.,Jackson, C.J. Conformational Disorganization within the Active Site of a Recently Evolved Organophosphate Hydrolase Limits Its Catalytic Efficiency. Biochemistry, 55:1408-1417, 2016 Cited by PubMed: 26881849DOI: 10.1021/acs.biochem.5b01322 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.01 Å) |
Structure validation
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