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7TI6
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Crystal structure of the wild-type least mutated common ancestor (LMCA) of the HIV-targeting PCT64 antibody lineage
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, PCT64_LMCA Fab heavy chain, PCT64_LMCA light chain (wild type)
著者Omorodion, O, Wilson, I.A.
登録日2022-01-12
公開日2022-10-05
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors.
Immunity, 55, 2022
7T7B
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Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with a cross-neutralizing antibody ADI-62113 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ADI-62113 Fab heavy chain, ADI-62113 Fab light chain, ...
著者Liu, H, Wilson, I.A.
登録日2021-12-14
公開日2022-08-03
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Human antibodies to SARS-CoV-2 with a recurring YYDRxG motif retain binding and neutralization to variants of concern including Omicron.
Commun Biol, 5, 2022
7T1V
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BU of 7t1v by Molmil
Crystal structure of an equine H7 hemagglutinin from A/equine/NY/49/73 (H7N7) in complex with 3'-GcLN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
著者Zhu, X, Wilson, I.A.
登録日2021-12-02
公開日2022-01-12
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献N -Glycolylneuraminic Acid Binding of Avian and Equine H7 Influenza A Viruses.
J.Virol., 96, 2022
7SJS
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BU of 7sjs by Molmil
Crystal structure of SARS-CoV-2 spike stem helix peptide in complex with neutralizing antibody CC40.8
分子名称: ACETATE ION, CC40.8 Fab heavy chain, CC40.8 Fab light chain, ...
著者Yuan, M, Wilson, I.A.
登録日2021-10-18
公開日2022-01-12
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.612 Å)
主引用文献A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection.
Sci Transl Med, 14, 2022
7U8L
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Crystal structure of chimeric hemagglutinin cH15/3 in complex with broad protective antibody 31.a.83
分子名称: Antibody Fab light chain, Hemagglutinin HA1 subunit, Hemagglutinin HA2 subunit, ...
著者Zhu, X, Wilson, I.A.
登録日2022-03-08
公開日2022-06-08
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (4.56 Å)
主引用文献Influenza chimeric hemagglutinin structures in complex with broadly protective antibodies to the stem and trimer interface.
Proc.Natl.Acad.Sci.USA, 119, 2022
7U8J
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BU of 7u8j by Molmil
Crystal structure of chimeric hemagglutinin cH4/3 in complex with broad protective antibody 31.a.83
分子名称: Antibody Fab light chain, Hemagglutinin HA1 subunit, Hemagglutinin HA2 subunit, ...
著者Zhu, X, Wilson, I.A.
登録日2022-03-08
公開日2022-06-08
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (4.9 Å)
主引用文献Influenza chimeric hemagglutinin structures in complex with broadly protective antibodies to the stem and trimer interface.
Proc.Natl.Acad.Sci.USA, 119, 2022
7U8M
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Crystal structure of chimeric hemagglutinin cH15/3 in complex with broad protective antibodies 31.a.83 and FluA-20
分子名称: Antibody 31.a.83 Fab light chain, antibody 31.a.83 Fab heavy chain, antibody FluA-20 Fab heavy chain, ...
著者Zhu, X, Wilson, I.A.
登録日2022-03-08
公開日2022-06-08
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (5.39 Å)
主引用文献Influenza chimeric hemagglutinin structures in complex with broadly protective antibodies to the stem and trimer interface.
Proc.Natl.Acad.Sci.USA, 119, 2022
7U0K
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BU of 7u0k by Molmil
IOMA class antibody Fab ACS124
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, IOMA Class antibody ACS124 Heavy chain, IOMA Class antibody ACS124 Light chain
著者Farokhi, E, Stanfield, R.L, Wilson, I.A.
登録日2022-02-18
公開日2022-08-24
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Identification of IOMA-class neutralizing antibodies targeting the CD4-binding site on the HIV-1 envelope glycoprotein.
Nat Commun, 13, 2022
7U04
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IOMA class antibody ACS101
分子名称: GLYCEROL, IOMA class antibody ACS101 heavy chain, IOMA class antibody ACS101 light chain
著者Farokhi, E, Stanfield, R.L, Wilson, I.A.
登録日2022-02-17
公開日2022-08-24
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Identification of IOMA-class neutralizing antibodies targeting the CD4-binding site on the HIV-1 envelope glycoprotein.
Nat Commun, 13, 2022
5SY8
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Crystal structure of the complex of 10E8 Fab light chain mutant1 and T117v2 HIV-1 MPER scaffold
分子名称: 10E8 EPITOPE SCAFFOLD T117v2, 10E8 FAB HEAVY CHAIN, 10E8 FAB LIGHT CHAIN, ...
著者Irimia, A, Wilson, I.A.
登録日2016-08-10
公開日2017-03-08
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design.
PLoS Pathog., 13, 2017
5T5B
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BU of 5t5b by Molmil
CRYSTAL STRUCTURE OF THE COMPLEX OF 10E8 FAB LIGHT CHAIN MUTANT5 AND T117V2 HIV-1 MPER SCAFFOLD
分子名称: 10E8 EPITOPE SCAFFOLD T117V2, Antibody 10E8 FAB HEAVY CHAIN, Antibody 10E8 FAB LIGHT CHAIN MUTATED, ...
著者Irimia, A, Wilson, I.A.
登録日2016-08-30
公開日2017-03-08
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design.
PLoS Pathog., 13, 2017
5TH0
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BU of 5th0 by Molmil
Crystal structure of H10 hemagglutinin mutant (K158aA-Q226L-G228S) from Jiangxi-Donghu (2013) H10N8 influenza virus
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
著者Tzarum, N, Wilson, I.A.
登録日2016-09-28
公開日2017-04-05
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献The 150-Loop Restricts the Host Specificity of Human H10N8 Influenza Virus.
Cell Rep, 19, 2017
5THC
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BU of 5thc by Molmil
Crystal structure of H10 hemagglutinin mutant (T193D-Q226L-G228S) from Jiangxi-Donghu (2013) H10N8 influenza virus in complex with 6'-SLNLN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
著者Tzarum, N, Wilson, I.A.
登録日2016-09-29
公開日2017-04-05
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.792 Å)
主引用文献The 150-Loop Restricts the Host Specificity of Human H10N8 Influenza Virus.
Cell Rep, 19, 2017
5T6L
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Crystal structure of 10E8 Fab in complex with the MPER epitope scaffold T117v2
分子名称: 10E8 EPITOPE SCAFFOLD T117V2, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Antibody 10E8 FAB HEAVY CHAIN, ...
著者Irimia, A, Wilson, I.A.
登録日2016-09-01
公開日2017-03-08
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design.
PLoS Pathog., 13, 2017
5TGO
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BU of 5tgo by Molmil
Crystal structure of H10 hemagglutinin mutant (K158aA-D193T-Q226L-G228S) from Jiangxi-Donghu (2013) H10N8 influenza virus
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
著者Tzarum, N, Wilson, I.A.
登録日2016-09-28
公開日2017-04-05
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献The 150-Loop Restricts the Host Specificity of Human H10N8 Influenza Virus.
Cell Rep, 19, 2017
5TGU
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BU of 5tgu by Molmil
Crystal structure of H10 hemagglutinin mutant (K158aA-D193T-Q226L-G228S) from Jiangxi-Donghu (2013) H10N8 influenza virus in complex with 6'-SLNLN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
著者Tzarum, N, Wilson, I.A.
登録日2016-09-28
公開日2017-04-05
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献The 150-Loop Restricts the Host Specificity of Human H10N8 Influenza Virus.
Cell Rep, 19, 2017
5T29
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Crystal structure of 10E8 Fab light chain mutant3, against the MPER region of the HIV-1 Env, in complex with the MPER epitope scaffold T117v2
分子名称: 10E8 EPITOPE SCAFFOLD T117V2, Antibody 10E8 FAB HEAVY CHAIN, Antibody 10E8 FAB LIGHT CHAIN, ...
著者Irimia, A, Wilson, I.A.
登録日2016-08-23
公開日2017-03-08
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design.
PLoS Pathog., 13, 2017
5T3S
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BU of 5t3s by Molmil
HIV gp140 trimer MD39-10MUTA in complex with Fabs PGT124 and 35022
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
著者Stanfield, R.L, Wilson, I.A.
登録日2016-08-26
公開日2016-09-28
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (4.5 Å)
主引用文献HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies.
Immunity, 45, 2016
5THB
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BU of 5thb by Molmil
Crystal structure of H10 hemagglutinin mutant (T193D-Q226L-G228S) from Jiangxi-Donghu (2013) H10N8 influenza virus
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
著者Tzarum, N, Wilson, I.A.
登録日2016-09-29
公開日2017-04-05
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献The 150-Loop Restricts the Host Specificity of Human H10N8 Influenza Virus.
Cell Rep, 19, 2017
5TGV
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BU of 5tgv by Molmil
Crystal structure of H10 hemagglutinin mutant (K158aA-D193T-Q226L-G228S) from Jiangxi-Donghu (2013) H10N8 influenza virus in complex with 3'-SLN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
著者Tzarum, N, Wilson, I.A.
登録日2016-09-28
公開日2017-04-05
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.974 Å)
主引用文献The 150-Loop Restricts the Host Specificity of Human H10N8 Influenza Virus.
Cell Rep, 19, 2017
5U7G
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BU of 5u7g by Molmil
Crystal Structure of the Catalytic Core of CBP
分子名称: CREB-binding protein, ZINC ION
著者Park, S, Stanfield, R.L, Martinez-Yamout, M.M, Dyson, H.J, Wilson, I.A, Wright, P.E.
登録日2016-12-12
公開日2017-06-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.401 Å)
主引用文献Role of the CBP catalytic core in intramolecular SUMOylation and control of histone H3 acetylation.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5UEI
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BU of 5uei by Molmil
Crystal Structure of Variable Lymphocyte Receptor (VLR) O13 (Apo)
分子名称: CHLORIDE ION, GLYCEROL, O13
著者Gunn, R.J, Collins, B.C, McKitrick, T.R, Cummings, R.D, Herrin, B.R, Cooper, M.D, Wilson, I.A.
登録日2017-01-02
公開日2017-10-18
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.702 Å)
主引用文献Structural Insights into VLR Fine Specificity for Blood Group Carbohydrates.
Structure, 25, 2017
5TFW
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BU of 5tfw by Molmil
Crystal structure of 10E8 Fab light chain mutant2 against the MPER region of the HIV-1 Env, in complex with T117v2 epitope scaffold
分子名称: 1,2-ETHANEDIOL, 10E8 EPITOPE SCAFFOLD T117V2, Antibody 10E8 FAB HEAVY CHAIN, ...
著者Irimia, A, Wilson, I.A.
登録日2016-09-26
公開日2017-03-08
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.168 Å)
主引用文献Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design.
PLoS Pathog., 13, 2017
5T6N
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BU of 5t6n by Molmil
Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin in complex with the antiviral drug arbidol
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
著者Kadam, R.U, Wilson, I.A.
登録日2016-09-01
公開日2017-01-04
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.541 Å)
主引用文献Structural basis of influenza virus fusion inhibition by the antiviral drug Arbidol.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5T80
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Crystal structure of 10E8 Fab in complex with the MPER epitope scaffold T117v2 and phosphatidic acid (06:0 PA)
分子名称: (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, 10E8 EPITOPE SCAFFOLD T117V2, Antibody 10E8 FAB HEAVY CHAIN, ...
著者Irimia, A, Wilson, I.A.
登録日2016-09-06
公開日2017-03-08
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design.
PLoS Pathog., 13, 2017

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