3FZM
| Crystal Structures of Hsc70/Bag1 in Complex with Small Molecule Inhibitors | 分子名称: | 4-[[(2R,3S,4R,5R)-5-[6-amino-8-(quinolin-6-ylmethylamino)purin-9-yl]-3,4-dihydroxy-oxolan-2-yl]methoxymethyl]benzonitri le, BAG family molecular chaperone regulator 1, Heat shock cognate 71 kDa protein | 著者 | Dokurno, P, Williamson, D.S, Murray, J.B, Surgenor, A.E. | 登録日 | 2009-01-26 | 公開日 | 2009-03-17 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Novel adenosine-derived inhibitors of 70 kDa heat shock protein, discovered through structure-based design J.Med.Chem., 52, 2009
|
|
7COC
| |
7COB
| |
7CO8
| Ternary complex of DNA polymerase Mu with 2-nt gapped DNA (T:dGMPNPP) | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*GP*GP*CP*TP*TP*TP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*A)-3'), ... | 著者 | Guo, M, Zhao, Y. | 登録日 | 2020-08-04 | 公開日 | 2021-06-30 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.697 Å) | 主引用文献 | Mechanism of genome instability mediated by human DNA polymerase mu misincorporation. Nat Commun, 12, 2021
|
|
7CO6
| |
7COD
| |
7CO9
| |
3FZK
| Crystal Structures of Hsc70/Bag1 in Complex with Small Molecule Inhibitors | 分子名称: | (2R,3R,4S,5R)-2-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BAG family molecular chaperone regulator 1, ... | 著者 | Dokurno, P, Williamson, D.S, Murray, J.B, Surgenor, A.E. | 登録日 | 2009-01-26 | 公開日 | 2009-03-17 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Novel adenosine-derived inhibitors of 70 kDa heat shock protein, discovered through structure-based design J.Med.Chem., 52, 2009
|
|
7COA
| |
3G49
| |
6KXS
| Cryo-EM structure of human IgM-Fc in complex with the J chain and the ectodomain of pIgR | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ... | 著者 | Li, Y, Wang, G, Xiao, J. | 登録日 | 2019-09-12 | 公開日 | 2020-02-05 | 最終更新日 | 2021-12-15 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural insights into immunoglobulin M. Science, 367, 2020
|
|
6KPP
| BNC105 in complex with tubulin | 分子名称: | (6-methoxy-2-methyl-7-oxidanyl-1-benzofuran-3-yl)-(3,4,5-trimethoxyphenyl)methanone, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | 著者 | Wang, T, Wu, C, Pu, D. | 登録日 | 2019-08-15 | 公開日 | 2020-08-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.74524117 Å) | 主引用文献 | Unraveling the molecular mechanism of BNC105, a phase II clinical trial vascular disrupting agent, provides insights into drug design. Biochem.Biophys.Res.Commun., 2020
|
|
3FZH
| Crystal Structures of Hsc70/Bag1 in Complex with Small Molecule Inhibitors | 分子名称: | (2R,3R,4S,5R)-2-(6,8-diaminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol, BAG family molecular chaperone regulator 1, Heat shock cognate 71 kDa protein | 著者 | Dokurno, P, Williamson, D.S, Murray, J.B, Surgenor, A.E. | 登録日 | 2009-01-26 | 公開日 | 2009-03-17 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Novel adenosine-derived inhibitors of 70 kDa heat shock protein, discovered through structure-based design J.Med.Chem., 52, 2009
|
|
3FZF
| Crystal Structure of Hsc70/Bag1 in complex with ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, BAG family molecular chaperone regulator 1, Heat shock cognate 71 kDa protein | 著者 | Dokurno, P, Williamson, D.S, Murray, J.B, Surgenor, A.E. | 登録日 | 2009-01-26 | 公開日 | 2009-03-17 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Novel adenosine-derived inhibitors of 70 kDa heat shock protein, discovered through structure-based design J.Med.Chem., 52, 2009
|
|
6L31
| L1 protein of human papillomavirus 6 | 分子名称: | Major capsid protein L1 | 著者 | Li, S.W, Liu, X.L, Gu, Y. | 登録日 | 2019-10-07 | 公開日 | 2019-12-25 | 実験手法 | ELECTRON MICROSCOPY (4.18 Å) | 主引用文献 | Neutralization sites of human papillomavirus-6 relate to virus attachment and entry phase in viral infection. Emerg Microbes Infect, 8, 2019
|
|
6LDZ
| Crystal structure of Rv0222 from Mycobacterium tuberculosis | 分子名称: | Probable enoyl-CoA hydratase EchA1 (Enoyl hydrase) (Unsaturated acyl-CoA hydratase) (Crotonase) | 著者 | Li, J, Ran, Y.J, Wang, L, Wu, J.H, Ge, B.X, Rao, Z.H. | 登録日 | 2019-11-23 | 公開日 | 2020-01-22 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Host-mediated ubiquitination of a mycobacterial protein suppresses immunity. Nature, 577, 2020
|
|
6L6V
| SPO1 Gp44 N-terminal region (1-55) | 分子名称: | E3 protein | 著者 | Liu, B, Wang, Z. | 登録日 | 2019-10-29 | 公開日 | 2021-05-05 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | A Bacteriophage DNA Mimic Protein Employs a Non-specific Strategy to Inhibit the Bacterial RNA Polymerase. Front Microbiol, 12, 2021
|
|
3FZL
| Crystal Structures of Hsc70/Bag1 in Complex with Small Molecule Inhibitors | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-[[(2R,3S,4R,5R)-5-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-3,4-dihydroxy-oxolan-2-yl]methoxymethyl]benzonitrile, BAG family molecular chaperone regulator 1, ... | 著者 | Dokurno, P, Williamson, D.S, Murray, J.B, Surgenor, A.E. | 登録日 | 2009-01-26 | 公開日 | 2009-03-17 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Novel adenosine-derived inhibitors of 70 kDa heat shock protein, discovered through structure-based design J.Med.Chem., 52, 2009
|
|
6LPM
| |
6KJY
| Galectin-13 variant C136S/C138S | 分子名称: | Galactoside-binding soluble lectin 13 | 著者 | Su, J. | 登録日 | 2019-07-23 | 公開日 | 2019-10-16 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Galectin-13/placental protein 13: redox-active disulfides as switches for regulating structure, function and cellular distribution. Glycobiology, 30, 2020
|
|
4GPI
| |
4GPZ
| |
8HGW
| |
8HGV
| |
6KJX
| Galectin-13 variant C138S | 分子名称: | Galactoside-binding soluble lectin 13 | 著者 | Su, J. | 登録日 | 2019-07-23 | 公開日 | 2019-10-16 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | Galectin-13/placental protein 13: redox-active disulfides as switches for regulating structure, function and cellular distribution. Glycobiology, 30, 2020
|
|