3EAX
| Crystal structure PTP1B complex with small molecule compound LZP-6 | 分子名称: | 4,4'-piperazine-1,4-diylbis{1-[3-(benzyloxy)phenyl]-4-oxobutane-1,3-dione}, Tyrosine-protein phosphatase non-receptor type 1 | 著者 | Zhang, Z.-Y, Liu, S, Zhang, L.-F, Yu, X, Xue, T, Gunawan, A.M, Long, Y.-Q. | 登録日 | 2008-08-26 | 公開日 | 2009-07-07 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Targeting inactive enzyme conformation: aryl diketoacid derivatives as a new class of PTP1B inhibitors. J.Am.Chem.Soc., 130, 2008
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3EB1
| Crystal structure PTP1B complex with small molecule inhibitor LZP-25 | 分子名称: | 4-[3-(dibenzylamino)phenyl]-2,4-dioxobutanoic acid, Tyrosine-protein phosphatase non-receptor type 1 | 著者 | Liu, S, Zheng, L.-F, Wu, L, Yu, X, Xue, T, Gunawan, A.M, Long, Y.-Q, Zhang, Z.-Y. | 登録日 | 2008-08-26 | 公開日 | 2009-07-07 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Targeting inactive enzyme conformation: aryl diketoacid derivatives as a new class of PTP1B inhibitors. J.Am.Chem.Soc., 130, 2008
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3F9V
| Crystal Structure Of A Near Full-Length Archaeal MCM: Functional Insights For An AAA+ Hexameric Helicase | 分子名称: | Minichromosome maintenance protein MCM | 著者 | Chen, X.J, Brewster, A.S, Wang, G.G, Yu, X, Greenleaf, W, Tjajadi, M, Klein, M. | 登録日 | 2008-11-14 | 公開日 | 2008-12-30 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (4.35 Å) | 主引用文献 | Crystal structure of a near-full-length archaeal MCM: Functional insights for an AAA+ hexameric helicase. Proc.Natl.Acad.Sci.USA, 105, 2008
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3DOS
| Crystal structure of the complex of the Caf1M chaperone with the mini-fiber of two Caf1 subunits (Caf1:Caf1), carrying the Thr7Phe and Ala9Val mutations in the Gd donor strand | 分子名称: | Chaperone protein caf1M, F1 capsule antigen | 著者 | Fooks, L.J, Yu, X, Moslehi-Mohebi, E, Tischenko, V, Knight, S.D, MacIntyre, S, Zavialov, A.V. | 登録日 | 2008-07-06 | 公開日 | 2009-07-14 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Hydrophobicity and rigidity of binding segments enable CAF1M chaperone to act as assembly catalyst TO BE PUBLISHED
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6O6B
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6OVX
| Crystal structure of mithramycin 3-side chain keto-reductase MtmW in complex with NAD+, P422 form | 分子名称: | GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Putative side chain reductase | 著者 | Hou, C, Yu, X, Rohr, J, Tsodikov, O.V. | 登録日 | 2019-05-08 | 公開日 | 2019-11-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Discovery of a Cryptic Intermediate in Late Steps of Mithramycin Biosynthesis. Angew.Chem.Int.Ed.Engl., 59, 2020
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6OVQ
| Crystal structure of mithramycin 3-side chain keto-reductase MtmW | 分子名称: | GLYCEROL, Putative Side chain reductase | 著者 | Hou, C, Yu, X, Rohr, J, Tsodikov, O.V. | 登録日 | 2019-05-08 | 公開日 | 2019-11-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Discovery of a Cryptic Intermediate in Late Steps of Mithramycin Biosynthesis. Angew.Chem.Int.Ed.Engl., 59, 2020
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3DPB
| Crystal structure of the complex of the Caf1M chaperone with the mini-fiber of two Caf1 subunits (Caf1:Caf1), carrying the Ala9Val, Ala11Val, and Leu13Val mutations in the Gd donor strand | 分子名称: | Chaperone protein caf1M, F1 capsule antigen | 著者 | Fooks, L.J, Yu, X, Moslehi-Mohebi, E, Tischenko, V, Knight, S.D, MacIntyre, S, Zavialov, A.V. | 登録日 | 2008-07-07 | 公開日 | 2009-07-14 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Hydrophobicity and rigidity of binding segments enable CAF1M chaperone to act as assembly catalyst To be published
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6OW0
| Crystal structure of mithramycin 3-side chain keto-reductase MtmW in complex with NAD+ and PEG | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, MtmW, ... | 著者 | Hou, C, Yu, X, Rohr, J, Tsodikov, O.V. | 登録日 | 2019-05-08 | 公開日 | 2019-11-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | 主引用文献 | Discovery of a Cryptic Intermediate in Late Steps of Mithramycin Biosynthesis. Angew.Chem.Int.Ed.Engl., 59, 2020
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3DSN
| Crystal structure of the complex of the Caf1M chaperone with the mini-fiber of two Caf1 subunits (Caf1:Caf1), carrying the Thr7Phe mutation in the Gd donor strand | 分子名称: | Chaperone protein caf1M, F1 capsule antigen | 著者 | Fooks, L.J, Yu, X, Moslehi-Mohebi, E, Tischenko, V, Knight, S.D, MacIntyre, S, Zavialov, A.V. | 登録日 | 2008-07-13 | 公開日 | 2009-07-14 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Hydrophobicity and rigidity of binding segments enable CAF1M chaperone to act as assembly catalyst To be Published
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6NZU
| Structure of the human frataxin-bound iron-sulfur cluster assembly complex | 分子名称: | Acyl carrier protein, Cysteine desulfurase, mitochondrial, ... | 著者 | Fox, N.G, Yu, X, Xidong, F, Alain, M, Joseph, N, Claire, S.D, Christine, B, Han, S, Yue, W.W. | 登録日 | 2019-02-14 | 公開日 | 2019-05-22 | 最終更新日 | 2019-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structure of the human frataxin-bound iron-sulfur cluster assembly complex provides insight into its activation mechanism. Nat Commun, 10, 2019
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5A2T
| The Molecular Basis for Flexibility in the Flexible Filamentous Plant Viruses | 分子名称: | BAMBOO MOSAIC VIRUS, COAT PROTEIN | 著者 | DiMaio, F, Chen, C.C, Yu, X, Frenz, B, Hsu, Y.H, Lin, N.S, Egelman, E.H. | 登録日 | 2015-05-23 | 公開日 | 2015-07-22 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (5.6 Å) | 主引用文献 | The Molecular Basis for Flexibility in the Flexible Filamentous Plant Viruses. Nat.Struct.Mol.Biol., 22, 2015
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7SWD
| Structure of EBOV GP lacking the mucin-like domain with 1C11 scFv and 1C3 Fab bound | 分子名称: | 1C11 scFv, 1C3 heavy chain, 1C3 light chain, ... | 著者 | Milligan, J.C, Yu, X, Saphire, E.O. | 登録日 | 2021-11-19 | 公開日 | 2022-04-06 | 最終更新日 | 2022-08-10 | 実験手法 | ELECTRON MICROSCOPY (3.59 Å) | 主引用文献 | Asymmetric and non-stoichiometric glycoprotein recognition by two distinct antibodies results in broad protection against ebolaviruses. Cell, 185, 2022
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5CHH
| Crystal structure of transcriptional regulator CdpR from Pseudomonas aeruginosa | 分子名称: | AraC family transcriptional regulator | 著者 | Zhao, J.R, Yu, X, Zhu, M, Kang, H.P, Kong, W.N, Ma, J.B, Deng, X, Gan, J.H, Liang, H.H. | 登録日 | 2015-07-10 | 公開日 | 2016-05-18 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural and Molecular Mechanism of CdpR Involved in Quorum-Sensing and Bacterial Virulence in Pseudomonas aeruginosa Plos Biol., 14, 2016
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3M5D
| Crystal structure of N-acetyl-L-ornithine transcarbamylase K302R mutant complexed with PALAO | 分子名称: | N-acetylornithine carbamoyltransferase, N~2~-acetyl-N~5~-(phosphonoacetyl)-L-ornithine, SULFATE ION | 著者 | Li, Y, Yu, X, Allewell, N.M, Tuchman, M, Shi, D. | 登録日 | 2010-03-12 | 公開日 | 2010-07-28 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Reversible post-translational carboxylation modulates the enzymatic activity of N-acetyl-L-ornithine transcarbamylase. Biochemistry, 49, 2010
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3M4N
| Crystal structure of N-acetyl-L-ornithine transcarbamylase K302A mutant complexed with PALAO | 分子名称: | N-acetylornithine carbamoyltransferase, N~2~-acetyl-N~5~-(phosphonoacetyl)-L-ornithine, SULFATE ION | 著者 | Li, Y, Yu, X, Allewell, N.M, Tuchman, M, Shi, D. | 登録日 | 2010-03-11 | 公開日 | 2010-07-28 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Reversible post-translational carboxylation modulates the enzymatic activity of N-acetyl-L-ornithine transcarbamylase. Biochemistry, 49, 2010
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3M5C
| Crystal structure of N-acetyl-L-ornithine transcarbamylase K302E mutant complexed with PALAO | 分子名称: | N-acetylornithine carbamoyltransferase, N~2~-acetyl-N~5~-(phosphonoacetyl)-L-ornithine, SULFATE ION | 著者 | Li, Y, Yu, X, Allewell, N.M, Tuchman, M, Shi, D. | 登録日 | 2010-03-12 | 公開日 | 2010-07-28 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Reversible post-translational carboxylation modulates the enzymatic activity of N-acetyl-L-ornithine transcarbamylase. Biochemistry, 49, 2010
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3M4J
| Crystal structure of N-acetyl-L-ornithine transcarbamylase complexed with PALAO | 分子名称: | N-acetylornithine carbamoyltransferase, N~2~-acetyl-N~5~-(phosphonoacetyl)-L-ornithine, SULFATE ION | 著者 | Li, Y, Yu, X, Allewell, N.M, Tuchman, M, Shi, D. | 登録日 | 2010-03-11 | 公開日 | 2010-07-28 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Reversible Post-Translational Carboxylation Modulates the Enzymatic Activity of N-Acetyl-l-ornithine Transcarbamylase. Biochemistry, 49, 2010
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2HI5
| Model for bacteriophage fd from cryo-EM | 分子名称: | Coat protein B | 著者 | Wang, Y.A, Yu, X, Overman, S, Tsuboi, M, Thomas, G.J, Egelman, E.H. | 登録日 | 2006-06-29 | 公開日 | 2007-08-07 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (8 Å) | 主引用文献 | The Structure of a Filamentous Bacteriophage J.Mol.Biol., 361, 2006
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3J9X
| A Virus that Infects a Hyperthermophile Encapsidates A-Form DNA | 分子名称: | DNA, coat protein | 著者 | DiMaio, F, Yu, X, Rensen, E, Krupovic, M, Prangishvili, D, Egelman, E. | 登録日 | 2015-03-21 | 公開日 | 2015-06-03 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | A virus that infects a hyperthermophile encapsidates A-form DNA. Science, 348, 2015
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3J89
| Structural Plasticity of Helical Nanotubes Based on Coiled-Coil Assemblies | 分子名称: | synthetic peptide | 著者 | Egelman, E.H, Xu, C, DiMaio, F, Magnotti, E, Modlin, C, Yu, X, Wright, E, Baker, D, Conticello, V.P. | 登録日 | 2014-10-07 | 公開日 | 2015-02-11 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural plasticity of helical nanotubes based on coiled-coil assemblies. Structure, 23, 2015
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3J9R
| Atomic structures of a bactericidal contractile nanotube in its pre- and post-contraction states | 分子名称: | sheath | 著者 | Ge, P, Scholl, D, Leiman, P.G, Yu, X, Miller, J.F, Zhou, Z.H. | 登録日 | 2015-02-17 | 公開日 | 2015-04-01 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Atomic structures of a bactericidal contractile nanotube in its pre- and postcontraction states. Nat.Struct.Mol.Biol., 22, 2015
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3J9Q
| Atomic structures of a bactericidal contractile nanotube in its pre- and post-contraction states | 分子名称: | sheath, tube | 著者 | Ge, P, Scholl, D, Leiman, P.G, Yu, X, Miller, J.F, Zhou, Z.H. | 登録日 | 2015-02-17 | 公開日 | 2015-04-01 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Atomic structures of a bactericidal contractile nanotube in its pre- and postcontraction states. Nat.Struct.Mol.Biol., 22, 2015
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7JR7
| Cryo-EM structure of ABCG5/G8 in complex with Fab 2E10 and 11F4 | 分子名称: | ATP-binding cassette sub-family G member 5, ATP-binding cassette sub-family G member 8, Fab 11F4 heavy chain, ... | 著者 | Huang, C.S, Yu, X, Min, X, Wang, Z, Zhang, H. | 登録日 | 2020-08-11 | 公開日 | 2021-04-07 | 最終更新日 | 2021-05-12 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cryo-EM structure of ABCG5/G8 in complex with modulating antibodies Commun Biol, 4, 2021
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7N6P
| Crystal structure of the anti-EBOV and SUDV monoclonal antibody 1C3 Fab | 分子名称: | 1C3 Fab heavy chain, 1C3 Fab light chain | 著者 | Milligan, J.C, Yu, X, Buck, T, Saphire, E.O. | 登録日 | 2021-06-08 | 公開日 | 2022-04-06 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Asymmetric and non-stoichiometric glycoprotein recognition by two distinct antibodies results in broad protection against ebolaviruses. Cell, 185, 2022
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