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8IBT
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BU of 8ibt by Molmil
Crystal structure of GH42 beta-galactosidase BiBga42A from Bifidobacterium longum subspecies infantis E318S mutant in complex with lacto-N-tetraose
分子名称: Beta-galactosidase, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
著者Hidaka, M, Fushinobu, S, Gotoh, A, Katayama, T.
登録日2023-02-10
公開日2023-06-07
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Substrate recognition mode of a glycoside hydrolase family 42 beta-galactosidase from Bifidobacterium longum subspecies infantis ( Bi Bga42A) revealed by crystallographic and mutational analyses.
Microbiome Res Rep, 2, 2023
8IBS
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Crystal structure of GH42 beta-galactosidase BiBga42A from Bifidobacterium longum subspecies infantis E160A/E318A mutant in complex with galactose
分子名称: Beta-galactosidase, alpha-D-galactopyranose
著者Hidaka, M, Fushinobu, S, Gotoh, A, Katayama, T.
登録日2023-02-10
公開日2023-06-07
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Substrate recognition mode of a glycoside hydrolase family 42 beta-galactosidase from Bifidobacterium longum subspecies infantis ( Bi Bga42A) revealed by crystallographic and mutational analyses.
Microbiome Res Rep, 2, 2023
8IBR
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Crystal structure of GH42 beta-galactosidase BiBga42A from Bifidobacterium longum subspecies infantis in complex with glycerol
分子名称: Beta-galactosidase, DI(HYDROXYETHYL)ETHER, GLYCEROL
著者Hidaka, M, Fushinobu, S, Gotoh, A, Katayama, T.
登録日2023-02-10
公開日2023-06-07
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Substrate recognition mode of a glycoside hydrolase family 42 beta-galactosidase from Bifidobacterium longum subspecies infantis ( Bi Bga42A) revealed by crystallographic and mutational analyses.
Microbiome Res Rep, 2, 2023
6J79
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Fusion protein of heme oxygenase-1 and NADPH-cytochrome P450 reductase (13aa)
分子名称: FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, Heme oxygenase 1,NADPH--cytochrome P450 reductase, ...
著者Sugishima, M, Wada, K.
登録日2019-01-17
公開日2019-04-10
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.331 Å)
主引用文献Crystal structure of a NADPH-cytochrome P450 oxidoreductase (CYPOR) and heme oxygenase 1 fusion protein implies a conformational change in CYPOR upon NADPH/NADP+binding.
Febs Lett., 593, 2019
7E2O
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BU of 7e2o by Molmil
X-ray Crystal structure of PPARgamma R288H mutant.
分子名称: Peroxisome proliferator-activated receptor gamma
著者Egawa, D, Itoh, T.
登録日2021-02-06
公開日2022-01-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural Insights into the Loss-of-Function R288H Mutant of Human PPAR gamma.
Biol.Pharm.Bull., 44, 2021
2D4D
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BU of 2d4d by Molmil
The Crystal Structure of human beta2-microglobulin, L39W W60F W95F Mutant
分子名称: Beta-2-microglobulin, SODIUM ION
著者Iwata, K, Matsuura, T, Nakagawa, A, Goto, Y.
登録日2005-10-17
公開日2006-08-08
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Conformation of Amyloid Fibrils of beta2-Microglobulin Probed by Tryptophan Mutagenesis
J.Biol.Chem., 281, 2006
2D4F
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The Crystal Structure of human beta2-microglobulin
分子名称: Beta-2-microglobulin, SODIUM ION
著者Iwata, K, Matsuura, T, Nakagawa, A, Goto, Y.
登録日2005-10-18
公開日2006-08-08
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Conformation of Amyloid Fibrils of beta2-Microglobulin Probed by Tryptophan Mutagenesis
J.Biol.Chem., 281, 2006
7V4F
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Unique non-heme hydroxylase in biosynthesis of nucleoside antibiotic pathway uncover mechanism of reaction
分子名称: (2S,3S)-2-azanyl-4-(2-hydroxy-2-oxoethylamino)-3-oxidanyl-butanoic acid, Beta-hydroxylase, CARBON DIOXIDE, ...
著者Li, T.L, Saeid, M.Z.
登録日2021-08-13
公開日2022-02-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献beta-Hydroxylation of alpha-amino-beta-hydroxylbutanoyl-glycyluridine catalyzed by a nonheme hydroxylase ensures the maturation of caprazamycin
Commun Chem, 5, 2022
7V4O
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Unique non-heme hydroxylase in biosynthesis of nucleoside antibiotic pathway uncover mechanism of reaction
分子名称: 3,6,9,12,15-PENTAOXAHEPTADECANE, Beta-hydroxylase
著者Li, T.L, Saeid, M.Z.
登録日2021-08-13
公開日2022-02-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献beta-Hydroxylation of alpha-amino-beta-hydroxylbutanoyl-glycyluridine catalyzed by a nonheme hydroxylase ensures the maturation of caprazamycin
Commun Chem, 5, 2022
7V4N
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Unique non-heme hydroxylase in biosynthesis of nucleoside antibiotic pathway uncover mechanism of reaction
分子名称: Beta-hydroxylase, FE (III) ION
著者Li, T.L, Saeid, M.Z.
登録日2021-08-13
公開日2022-02-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献beta-Hydroxylation of alpha-amino-beta-hydroxylbutanoyl-glycyluridine catalyzed by a nonheme hydroxylase ensures the maturation of caprazamycin
Commun Chem, 5, 2022
7V4M
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BU of 7v4m by Molmil
Unique non-heme hydroxylase in biosynthesis of nucleoside antibiotic pathway uncover mechanism of reaction
分子名称: 2-OXOGLUTARIC ACID, Beta-hydroxylase, FE (III) ION, ...
著者Li, T.L, Saeid, M.Z.
登録日2021-08-13
公開日2022-02-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献beta-Hydroxylation of alpha-amino-beta-hydroxylbutanoyl-glycyluridine catalyzed by a nonheme hydroxylase ensures the maturation of caprazamycin
Commun Chem, 5, 2022
7V4P
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Unique non-heme hydroxylase in biosynthesis of nucleoside antibiotic pathway uncover mechanism of reaction
分子名称: Beta-hydroxylase, FE (III) ION
著者Li, T.L, Saeid, M.Z.
登録日2021-08-13
公開日2022-02-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献beta-Hydroxylation of alpha-amino-beta-hydroxylbutanoyl-glycyluridine catalyzed by a nonheme hydroxylase ensures the maturation of caprazamycin
Commun Chem, 5, 2022
1BDM
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BU of 1bdm by Molmil
THE STRUCTURE AT 1.8 ANGSTROMS RESOLUTION OF A SINGLE SITE MUTANT (T189I) OF MALATE DEHYDROGENASE FROM THERMUS FLAVUS WITH INCREASED ENZYMATIC ACTIVITY
分子名称: BETA-6-HYDROXY-1,4,5,6-TETRHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, MALATE DEHYDROGENASE
著者Kelly, C.A, Birktoft, J.J.
登録日1993-02-16
公開日1994-12-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Determinants of protein thermostability observed in the 1.9-A crystal structure of malate dehydrogenase from the thermophilic bacterium Thermus flavus.
Biochemistry, 32, 1993
3WCS
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BU of 3wcs by Molmil
Crystal structure of plant lectin (ligand-bound form)
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose, ...
著者Nagae, M, Yamaguchi, Y.
登録日2013-05-31
公開日2014-04-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Phytohemagglutinin from Phaseolus vulgaris (PHA-E) displays a novel glycan recognition mode using a common legume lectin fold
Glycobiology, 24, 2014
3WOG
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Crystal structure plant lectin in complex with ligand
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose, CALCIUM ION, ...
著者Nagae, M, Yamaguchi, Y.
登録日2013-12-26
公開日2014-04-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Phytohemagglutinin from Phaseolus vulgaris (PHA-E) displays a novel glycan recognition mode using a common legume lectin fold
Glycobiology, 24, 2014
5B1W
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Crystal structure of human dendritic cell inhibitory receptor (DCIR) C-type lectin domain in ligand-free form
分子名称: C-type lectin domain family 4 member A, CALCIUM ION
著者Nagae, M, Yamaguchi, Y.
登録日2015-12-21
公開日2016-05-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Crystal structure of human dendritic cell inhibitory receptor C-type lectin domain reveals the binding mode with N-glycan
Febs Lett., 590, 2016
3WCR
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Crystal structure of plant lectin (ligand-free form)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, BROMIDE ION, Erythroagglutinin
著者Nagae, M, Yamaguchi, Y.
登録日2013-05-31
公開日2014-04-09
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Phytohemagglutinin from Phaseolus vulgaris (PHA-E) displays a novel glycan recognition mode using a common legume lectin fold
Glycobiology, 24, 2014
5B1X
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Crystal structure of human dendritic cell inhibitory receptor (DCIR) C-type lectin domain in complex with biantennary glycan
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose, C-type lectin domain family 4 member A, CALCIUM ION
著者Nagae, M, Yamaguchi, Y.
登録日2015-12-21
公開日2016-05-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.902 Å)
主引用文献Crystal structure of human dendritic cell inhibitory receptor C-type lectin domain reveals the binding mode with N-glycan
Febs Lett., 590, 2016
2Z8F
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The galacto-N-biose-/lacto-N-biose I-binding protein (GL-BP) of the ABC transporter from Bifidobacterium longum in complex with lacto-N-tetraose
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Galacto-N-biose/lacto-N-biose I transporter substrate-binding protein, SODIUM ION, ...
著者Suzuki, R, Wada, J, Katayama, T, Fushinobu, S.
登録日2007-09-05
公開日2008-03-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural and thermodynamic analyses of solute-binding Protein from Bifidobacterium longum specific for core 1 disaccharide and lacto-N-biose I.
J.Biol.Chem., 283, 2008
2Z8E
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The galacto-N-biose-/lacto-N-biose I-binding protein (GL-BP) of the ABC transporter from Bifidobacterium longum in complex with galacto-N-biose
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Galacto-N-biose/lacto-N-biose I transporter substrate-binding protein, ZINC ION, ...
著者Suzuki, R, Wada, J, Katayama, T, Fushinobu, S.
登録日2007-09-05
公開日2008-03-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structural and thermodynamic analyses of solute-binding Protein from Bifidobacterium longum specific for core 1 disaccharide and lacto-N-biose I.
J.Biol.Chem., 283, 2008
2Z8D
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The galacto-N-biose-/lacto-N-biose I-binding protein (GL-BP) of the ABC transporter from Bifidobacterium longum in complex with lacto-N-biose
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Galacto-N-biose/lacto-N-biose I transporter substrate-binding protein, ZINC ION, ...
著者Suzuki, R, Wada, J, Katayama, T, Fushinobu, S.
登録日2007-09-05
公開日2008-03-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural and thermodynamic analyses of solute-binding Protein from Bifidobacterium longum specific for core 1 disaccharide and lacto-N-biose I.
J.Biol.Chem., 283, 2008
6K5O
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Development of Novel Lithocholic Acid Derivatives as Vitamin D Receptor Agonists
分子名称: (4~{R})-4-[(3~{R},5~{R},8~{R},9~{S},10~{S},13~{R},14~{S},17~{R})-10,13-dimethyl-3-methylsulfonyloxy-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1~{H}-cyclopenta[a]phenanthren-17-yl]pentanoic acid, Mediator of RNA polymerase II transcription subunit 1, Vitamin D3 receptor
著者Masuno, H, Kagechika, H, Ito, N.
登録日2019-05-29
公開日2019-07-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Development of novel lithocholic acid derivatives as vitamin D receptor agonists.
Bioorg.Med.Chem., 27, 2019
7C7V
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Vitamin D3 receptor/lithochoric acid derivative complex
分子名称: (4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-3-(2-methyl-2-oxidanyl-propyl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid, FORMIC ACID, Mediator of RNA polymerase II transcription subunit 1, ...
著者Masuno, H, Numoto, N, Kagechika, H, Ito, N.
登録日2020-05-26
公開日2021-01-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Lithocholic Acid Derivatives as Potent Vitamin D Receptor Agonists.
J.Med.Chem., 64, 2021
7C7W
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Vitamin D3 receptor/lithochoric acid derivative complex
分子名称: (4R)-4-[(3S,5R,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-3-(2-methyl-2-oxidanyl-propyl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid, FORMIC ACID, Mediator of RNA polymerase II transcription subunit 1, ...
著者Masuno, H, Numoto, N, Kagechika, H, Ito, N.
登録日2020-05-26
公開日2021-01-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Lithocholic Acid Derivatives as Potent Vitamin D Receptor Agonists.
J.Med.Chem., 64, 2021
5WZN
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Alpha-N-acetylgalactosaminidase NagBb from Bifidobacterium bifidum - GalNAc complex
分子名称: 2-acetamido-2-deoxy-alpha-D-galactopyranose, Alpha-N-acetylgalactosaminidase, CALCIUM ION, ...
著者Sato, M, Arakawa, T, Ashida, H, Fushinobu, S.
登録日2017-01-18
公開日2017-06-07
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The first crystal structure of a family 129 glycoside hydrolase from a probiotic bacterium reveals critical residues and metal cofactors
J. Biol. Chem., 292, 2017

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