8OUA
 
 | | Cereblon isoform 4 in complex with novel Benzamide-Type Cereblon Binder 11f | | 分子名称: | 4-azanyl-~{N}-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]-2,5-bis(fluoranyl)-3-methoxy-benzamide, Cereblon isoform 4, PHOSPHATE ION, ... | | 著者 | Heim, C, Bischof, L, Hartmann, M.D. | | 登録日 | 2023-04-22 | | 公開日 | 2023-11-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs.
J.Med.Chem., 66, 2023
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3G3Q
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3G3O
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3G3U
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3G3T
 | | Crystal structure of a eukaryotic polyphosphate polymerase in complex with orthophosphate | | 分子名称: | 1,2-ETHANEDIOL, PHOSPHATE ION, Vacuolar transporter chaperone 4 | | 著者 | Lenherr, E.D, Hothorn, M, Scheffzek, K. | | 登録日 | 2009-02-02 | | 公開日 | 2009-05-05 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Catalytic core of a membrane-associated eukaryotic polyphosphate polymerase.
Science, 324, 2009
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3G3R
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3H0D
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5MND
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3S6A
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3SHG
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3SN9
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3SE5
 | | Fic protein from NEISSERIA MENINGITIDIS mutant delta8 in complex with AMPPNP | | 分子名称: | Cell filamentation protein Fic-related protein, HEXAETHYLENE GLYCOL, MAGNESIUM ION, ... | | 著者 | Goepfert, A, Stanger, F, Schirmer, T. | | 登録日 | 2011-06-10 | | 公開日 | 2012-01-25 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Adenylylation control by intra- or intermolecular active-site obstruction in Fic proteins.
Nature, 482, 2012
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5LP2
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7KPA
 | | asymmetric hTNF-alpha | | 分子名称: | 5-(1-{[2-(difluoromethoxy)phenyl]methyl}-2-{[3-(2-oxopyrrolidin-1-yl)phenoxy]methyl}-1H-benzimidazol-6-yl)pyridin-2(1H)-one, Tumor necrosis factor | | 著者 | Fox III, D, Lukacs, C.M, Ceska, T. | | 登録日 | 2020-11-10 | | 公開日 | 2021-01-13 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | A conformation-selective monoclonal antibody against a small molecule-stabilised signalling-deficient form of TNF.
Nat Commun, 12, 2021
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7KPB
 | | Human TNF-alpha TNFR1 complex bound to conformationally selective antibody | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-(1-{[2-(difluoromethoxy)phenyl]methyl}-2-{[3-(2-oxopyrrolidin-1-yl)phenoxy]methyl}-1H-benzimidazol-6-yl)pyridin-2(1H)-one, Fab1974 - Heavy Chain, ... | | 著者 | Fox III, D, Conrady, D.G, Lowe, M, Ceska, T. | | 登録日 | 2020-11-10 | | 公開日 | 2021-01-13 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | A conformation-selective monoclonal antibody against a small molecule-stabilised signalling-deficient form of TNF
Nat Commun, 12, 2021
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2G4O
 | | anomalous substructure of 3-ISOPROPYLMALATE DEHYDROGENASE | | 分子名称: | 3-isopropylmalate dehydrogenase, CHLORIDE ION, SULFATE ION | | 著者 | Mueller-Dieckmann, C, Weiss, M.S. | | 登録日 | 2006-02-22 | | 公開日 | 2007-02-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | On the routine use of soft X-rays in macromolecular crystallography. Part IV. Efficient determination of anomalous substructures in biomacromolecules using longer X-ray wavelengths.
Acta Crystallogr.,Sect.D, 63, 2007
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2G4S
 | | Anomalous substructure of NBR1PB1 | | 分子名称: | ACETIC ACID, CHLORIDE ION, Next to BRCA1 gene 1 protein | | 著者 | Mueller-Dieckmann, C, Weiss, M.S. | | 登録日 | 2006-02-22 | | 公開日 | 2007-02-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | On the routine use of soft X-rays in macromolecular crystallography. Part IV. Efficient determination of anomalous substructures in biomacromolecules using longer X-ray wavelengths.
Acta Crystallogr.,Sect.D, 63, 2007
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2G4W
 | | anomalous substructure of ribonuclease A (C2) | | 分子名称: | CHLORIDE ION, Ribonuclease pancreatic, SULFATE ION | | 著者 | Mueller-Dieckmann, C, Weiss, M.S. | | 登録日 | 2006-02-22 | | 公開日 | 2007-02-20 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | On the routine use of soft X-rays in macromolecular crystallography. Part IV. Efficient determination of anomalous substructures in biomacromolecules using longer X-ray wavelengths.
Acta Crystallogr.,Sect.D, 63, 2007
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2G55
 | | Anomalous substructure of trypsin (P3121) | | 分子名称: | CALCIUM ION, CHLORIDE ION, Cationic trypsin | | 著者 | Mueller-Dieckmann, C, Weiss, M.S. | | 登録日 | 2006-02-22 | | 公開日 | 2007-02-20 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | On the routine use of soft X-rays in macromolecular crystallography. Part IV. Efficient determination of anomalous substructures in biomacromolecules using longer X-ray wavelengths.
Acta Crystallogr.,Sect.D, 63, 2007
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2G4R
 | | anomalous substructure of MogA | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, molybdopterin biosynthesis Mog protein | | 著者 | Mueller-Dieckmann, C, Weiss, M.S. | | 登録日 | 2006-02-22 | | 公開日 | 2007-02-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | On the routine use of soft X-rays in macromolecular crystallography. Part IV. Efficient determination of anomalous substructures in biomacromolecules using longer X-ray wavelengths.
Acta Crystallogr.,Sect.D, 63, 2007
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2G4V
 | | anomalous substructure of proteinase K | | 分子名称: | CALCIUM ION, CHLORIDE ION, POTASSIUM ION, ... | | 著者 | Mueller-Dieckmann, C, Weiss, M.S. | | 登録日 | 2006-02-22 | | 公開日 | 2007-02-20 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | On the routine use of soft X-rays in macromolecular crystallography. Part IV. Efficient determination of anomalous substructures in biomacromolecules using longer X-ray wavelengths.
Acta Crystallogr.,Sect.D, 63, 2007
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2G51
 | | anomalous substructure of trypsin (p1) | | 分子名称: | CHLORIDE ION, Trypsin | | 著者 | Mueller-Dieckmann, C, Weiss, M.S. | | 登録日 | 2006-02-22 | | 公開日 | 2007-02-20 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | On the routine use of soft X-rays in macromolecular crystallography. Part IV. Efficient determination of anomalous substructures in biomacromolecules using longer X-ray wavelengths.
Acta Crystallogr.,Sect.D, 63, 2007
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2G4I
 | | Anomalous substructure of Concanavalin A | | 分子名称: | CALCIUM ION, CHLORIDE ION, Concanavalin A, ... | | 著者 | Mueller-Dieckmann, C, Weiss, M.S. | | 登録日 | 2006-02-22 | | 公開日 | 2007-02-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | On the routine use of soft X-rays in macromolecular crystallography. Part IV. Efficient determination of anomalous substructures in biomacromolecules using longer X-ray wavelengths.
Acta Crystallogr.,Sect.D, 63, 2007
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2G4X
 | | Anomalous substructure od ribonuclease A (P3221) | | 分子名称: | CHLORIDE ION, SULFATE ION, ribonuclease pancreatic | | 著者 | Mueller-Dieckmann, C, Weiss, M.S. | | 登録日 | 2006-02-22 | | 公開日 | 2007-02-20 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | On the routine use of soft X-rays in macromolecular crystallography. Part IV. Efficient determination of anomalous substructures in biomacromolecules using longer X-ray wavelengths.
Acta Crystallogr.,Sect.D, 63, 2007
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2G52
 | | Anomalous substructure of trypsin (P21) | | 分子名称: | SULFATE ION, Trypsin | | 著者 | Mueller-Dieckmann, C, Weiss, M.S. | | 登録日 | 2006-02-22 | | 公開日 | 2007-02-20 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | On the routine use of soft X-rays in macromolecular crystallography. Part IV. Efficient determination of anomalous substructures in biomacromolecules using longer X-ray wavelengths.
Acta Crystallogr.,Sect.D, 63, 2007
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