7QQX
 
 | | SpCas9 bound to FANCF off-target5 DNA substrate | | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target5 non-target strand, FANCF off-target5 target strand, ... | | 著者 | Pacesa, M, Jinek, M. | | 登録日 | 2022-01-10 | | 公開日 | 2022-10-26 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis for Cas9 off-target activity.
Cell, 185, 2022
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7QR0
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7QQZ
 | | SpCas9 bound to FANCF off-target7 DNA substrate | | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target7 non-target strand, FANCF off-target7 target strand, ... | | 著者 | Pacesa, M, Jinek, M. | | 登録日 | 2022-01-10 | | 公開日 | 2022-10-26 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structural basis for Cas9 off-target activity.
Cell, 185, 2022
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7QQW
 | | SpCas9 bound to FANCF off-target4 DNA substrate | | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target4 non-target strand, FANCF off-target4 target strand, ... | | 著者 | Pacesa, M, Jinek, M. | | 登録日 | 2022-01-10 | | 公開日 | 2022-10-26 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural basis for Cas9 off-target activity.
Cell, 185, 2022
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7QR1
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7QR7
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2HVZ
 | | Solution structure of the RRM domain of SR rich factor 9G8 | | 分子名称: | Splicing factor, arginine/serine-rich 7 | | 著者 | Tintaru, A.M, Hautbergue, G.M, Golovanov, A.P, Lian, L.Y, Wilson, S.A. | | 登録日 | 2006-07-31 | | 公開日 | 2006-11-21 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Molecular basis of RNA recognition and TAP binding by the SR proteins SRp20 and 9G8.
Embo J., 25, 2006
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2OSQ
 | | NMR Structure of RRM-1 of Yeast NPL3 Protein | | 分子名称: | Nucleolar protein 3 | | 著者 | Deka, P, Bucheli, M, Skrisovska, L, Allain, F.H, Moore, C, Buratowski, S, Varani, G. | | 登録日 | 2007-02-06 | | 公開日 | 2007-12-18 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the yeast SR protein Npl3 and Interaction with mRNA 3'-end processing signals.
J.Mol.Biol., 375, 2008
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2OSR
 | | NMR Structure of RRM-2 of Yeast NPL3 Protein | | 分子名称: | Nucleolar protein 3 | | 著者 | Deka, P, Bucheli, M, Skrisovska, L, Allain, F.H, Moore, C, Buratowski, S, Varani, G. | | 登録日 | 2007-02-06 | | 公開日 | 2007-12-18 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the yeast SR protein Npl3 and Interaction with mRNA 3'-end processing signals.
J.Mol.Biol., 375, 2008
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8R8P
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8R62
 | | Solution structure of Risdiplam bound to the RNA duplex formed upon 5'-splice site recognition | | 分子名称: | 7-(4,7-diazaspiro[2.5]octan-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-1~{H}-pyrido[1,2-a]pyrimidin-4-one, RNA (5'-R(*AP*UP*AP*CP*(PSU)P*(PSU)P*AP*CP*CP*UP*G)-3'), RNA (5'-R(P*GP*GP*AP*GP*UP*AP*AP*GP*UP*CP*U)-3') | | 著者 | Malard, F, Campagne, S. | | 登録日 | 2023-11-20 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The diversity of splicing modifiers acting on A-1 bulged 5'-splice sites reveals rules for rational drug design.
Nucleic Acids Res., 52, 2024
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8R63
 | | Solution structure of branaplam bound to the RNA duplex formed upon 5'-splice site recognition | | 分子名称: | 5-(1~{H}-pyrazol-4-yl)-2-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]phenol, RNA (5'-R(*AP*UP*AP*CP*(PSU)P*(PSU)P*AP*CP*CP*UP*G)-3'), RNA (5'-R(P*GP*GP*AP*GP*UP*AP*AP*GP*UP*CP*U)-3') | | 著者 | Malard, F, Campagne, S. | | 登録日 | 2023-11-20 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The diversity of splicing modifiers acting on A-1 bulged 5'-splice sites reveals rules for rational drug design.
Nucleic Acids Res., 52, 2024
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8CF2
 | | Solution structure of the RNA helix formed by the 5'-end of U1 snRNA and an A-1 bulged 5'-splice site in complex with SMN-CY | | 分子名称: | 4-[(3~{S})-3-ethylpiperazin-1-yl]-2-fluoranyl-~{N}-(2-methylimidazo[1,2-a]pyrazin-6-yl)benzamide, RNA (5'-R(P*AP*UP*AP*CP*(PSU)P*(PSU)P*AP*CP*CP*UP*G)-3'), RNA (5'-R(P*GP*GP*AP*GP*UP*AP*AP*GP*UP*CP*U)-3') | | 著者 | Malard, F, Marquevielle, J, Campagne, S. | | 登録日 | 2023-02-02 | | 公開日 | 2024-02-21 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The diversity of splicing modifiers acting on A-1 bulged 5'-splice sites reveals rules for rational drug design.
Nucleic Acids Res., 52, 2024
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4CQ1
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