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7C4C
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The crystal structure of Trypanosoma brucei RNase D : GMP complex
分子名称: CCHC-type domain-containing protein, GUANOSINE-5'-MONOPHOSPHATE, MANGANESE (II) ION, ...
著者Gao, Y.Q, Gan, J.H.
登録日2020-05-15
公開日2021-04-07
実験手法X-RAY DIFFRACTION (2.265 Å)
主引用文献Structural basis for guide RNA trimming by RNase D ribonuclease in Trypanosoma brucei.
Nucleic Acids Res., 49, 2021
7C4B
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BU of 7c4b by Molmil
The crystal structure of Trypanosoma brucei RNase D : UMP complex
分子名称: CCHC-type domain-containing protein, MANGANESE (II) ION, URIDINE-5'-MONOPHOSPHATE, ...
著者Gao, Y.Q, Gan, J.H.
登録日2020-05-15
公開日2021-04-07
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.101 Å)
主引用文献Structural basis for guide RNA trimming by RNase D ribonuclease in Trypanosoma brucei.
Nucleic Acids Res., 49, 2021
7C45
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The crystal structure of Trypanosoma brucei RNase D complex with RNA U12
分子名称: CALCIUM ION, CCHC-type domain-containing protein, RNA (5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3'), ...
著者Gao, Y.Q, Gan, J.H.
登録日2020-05-15
公開日2021-04-07
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.769 Å)
主引用文献Structural basis for guide RNA trimming by RNase D ribonuclease in Trypanosoma brucei.
Nucleic Acids Res., 49, 2021
7C47
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The crystal structure of Trypanosoma brucei RNase D : CMP complex
分子名称: CCHC-type domain-containing protein, CYTIDINE-5'-MONOPHOSPHATE, MANGANESE (II) ION, ...
著者Gao, Y.Q, Gan, J.H.
登録日2020-05-15
公開日2021-04-07
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for guide RNA trimming by RNase D ribonuclease in Trypanosoma brucei.
Nucleic Acids Res., 49, 2021
7C42
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The crystal structure of Trypanosoma brucei RNase D
分子名称: CCHC-type domain-containing protein, ZINC ION
著者Gao, Y.Q, Gan, J.H.
登録日2020-05-14
公開日2021-04-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for guide RNA trimming by RNase D ribonuclease in Trypanosoma brucei.
Nucleic Acids Res., 49, 2021
7F7G
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a linear Peptide Inhibitors in complex with GK domain
分子名称: DLG4 GK domain, UNK-ARG-ILE-ARG-ARG-ASP-GLU-TYR-LEU-LYS-ALA-ILE-GLN-UNK
著者Shang, Y, Huang, X, Li, X, Zhang, M.
登録日2021-06-29
公開日2022-02-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.446 Å)
主引用文献Entropy of stapled peptide inhibitors in free state is the major contributor to the improvement of binding affinity with the GK domain.
Rsc Chem Biol, 2, 2021
7E9Q
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BU of 7e9q by Molmil
Cryo-EM structure of the SARS-CoV-2 S-6P in complex with 35B5 Fab(1 out RBD, state3)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 35B5 Fab, Light chain of 35B5 Fab, ...
著者Wang, X.F, Zhu, Y.Q.
登録日2021-03-04
公開日2022-03-09
最終更新日2022-09-21
実験手法ELECTRON MICROSCOPY (3.65 Å)
主引用文献A potent human monoclonal antibody with pan-neutralizing activities directly dislocates S trimer of SARS-CoV-2 through binding both up and down forms of RBD
Signal Transduct Target Ther, 7, 2022
7E9O
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Cryo-EM structure of the SARS-CoV-2 S-6P in complex with 35B5 Fab(3 up RBDs, state2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 35B5 Fab, Light chain of 35B5 Fab, ...
著者Wang, X.F, Zhu, Y.Q.
登録日2021-03-04
公開日2022-03-09
最終更新日2022-09-21
実験手法ELECTRON MICROSCOPY (3.41 Å)
主引用文献A potent human monoclonal antibody with pan-neutralizing activities directly dislocates S trimer of SARS-CoV-2 through binding both up and down forms of RBD
Signal Transduct Target Ther, 7, 2022
7E9P
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Cryo-EM structure of the SARS-CoV-2 S-6P in complex with 35B5 Fab(state2, local refinement of the RBD and 35B5 Fab)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 35B5 Fab, Light chain of 35B5 Fab, ...
著者Wang, X.F, Zhu, Y.Q.
登録日2021-03-04
公開日2022-03-23
最終更新日2022-09-21
実験手法ELECTRON MICROSCOPY (3.69 Å)
主引用文献A potent human monoclonal antibody with pan-neutralizing activities directly dislocates S trimer of SARS-CoV-2 through binding both up and down forms of RBD
Signal Transduct Target Ther, 7, 2022
7E9N
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Cryo-EM structure of the SARS-CoV-2 S-6P in complex with 35B5 Fab(1 down RBD, state1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 35B5 Fab, Light chain of 35B5 Fab, ...
著者Wang, X.F, Zhu, Y.Q.
登録日2021-03-04
公開日2022-04-06
最終更新日2022-09-21
実験手法ELECTRON MICROSCOPY (3.69 Å)
主引用文献A potent human monoclonal antibody with pan-neutralizing activities directly dislocates S trimer of SARS-CoV-2 through binding both up and down forms of RBD
Signal Transduct Target Ther, 7, 2022
7ENF
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Cryo-EM structure of the SARS-CoV-2 S-6P in complex with Fab30
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab30, ...
著者Wang, X.F, Zhu, Y.Q.
登録日2021-04-16
公開日2022-04-06
最終更新日2022-09-21
実験手法ELECTRON MICROSCOPY (2.76 Å)
主引用文献A potent human monoclonal antibody with pan-neutralizing activities directly dislocates S trimer of SARS-CoV-2 through binding both up and down forms of RBD
Signal Transduct Target Ther, 7, 2022
7ENG
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BU of 7eng by Molmil
Cryo-EM structure of the SARS-CoV-2 S-6P in complex with Fab30 (local refinement of the RBD and Fab30)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab30, Light chain of Fab30, ...
著者Wang, X.F, Zhu, Y.Q.
登録日2021-04-16
公開日2022-04-06
最終更新日2022-09-21
実験手法ELECTRON MICROSCOPY (3.59 Å)
主引用文献A potent human monoclonal antibody with pan-neutralizing activities directly dislocates S trimer of SARS-CoV-2 through binding both up and down forms of RBD
Signal Transduct Target Ther, 7, 2022
5YKS
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BU of 5yks by Molmil
Crystal structure of sucrose nonfermenting-related kinase (SNRK)
分子名称: SNF-related serine/threonine-protein kinase
著者Wang, Y.L, Wang, J, Wu, J.W.
登録日2017-10-16
公開日2017-11-08
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of the kinase and UBA domains of SNRK reveals a distinct UBA binding mode in the AMPK family.
Biochem. Biophys. Res. Commun., 495, 2018
5WHZ
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BU of 5whz by Molmil
PGDM1400-10E8v4 CODV Fab
分子名称: Anti-HIV CODV-Fab Heavy chain, Anti-HIV CODV-Fab Light chain
著者Lord, D.M, Wei, R.R.
登録日2017-07-18
公開日2017-10-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.549 Å)
主引用文献Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques.
Science, 358, 2017
5XMC
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BU of 5xmc by Molmil
Crystal structure of the auto-inhibited Nedd4 family E3 ligase Itch
分子名称: E3 ubiquitin-protein ligase Itchy
著者Shan, Z, Wen, W.
登録日2017-05-13
公開日2017-08-02
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Allosteric auto-inhibition and activation of the Nedd4 family E3 ligase Itch
EMBO Rep., 18, 2017
5WUJ
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BU of 5wuj by Molmil
Crystal structure of FliF-FliG complex from H. pylori
分子名称: Flagellar M-ring protein, Flagellar motor switch protein FliG, GLYCEROL
著者Au, S.W, Xue, C, Lam, K.H, Lee, S.H.
登録日2016-12-19
公開日2017-12-20
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the FliF-FliG complex from Helicobacter pylori yields insight into the assembly of the motor MS-C ring in the bacterial flagellum
J. Biol. Chem., 293, 2018
7F46
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BU of 7f46 by Molmil
Cryo-EM structure of the SARS-CoV-2 S-6P in complex with 35B5 Fab (state1, local refinement of the RBD, NTD and 35B5 Fab)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 35B5 Fab, Light chain of 35B5 Fab, ...
著者Wang, X.F, Zhu, Y.Q.
登録日2021-06-17
公開日2022-03-23
最終更新日2022-09-21
実験手法ELECTRON MICROSCOPY (4.79 Å)
主引用文献A potent human monoclonal antibody with pan-neutralizing activities directly dislocates S trimer of SARS-CoV-2 through binding both up and down forms of RBD
Signal Transduct Target Ther, 7, 2022
7CKG
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Crystal structure of TMSiPheRS complexed with TMSiPhe
分子名称: 4-(trimethylsilyl)-L-phenylalanine, Tyrosine--tRNA ligase
著者Sun, J.P, Wang, J.Y, Zhu, Z.L, He, Q.T, Xiao, P.
登録日2020-07-17
公開日2021-03-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.053 Å)
主引用文献DeSiphering receptor core-induced and ligand-dependent conformational changes in arrestin via genetic encoded trimethylsilyl 1 H-NMR probe.
Nat Commun, 11, 2020
7CKH
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Crystal structure of TMSiPheRS
分子名称: Tyrosine--tRNA ligase
著者Sun, J.P, Wang, J.Y, Zhu, Z.L, He, Q.T, Xiao, P.
登録日2020-07-17
公開日2021-03-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.79492676 Å)
主引用文献DeSiphering receptor core-induced and ligand-dependent conformational changes in arrestin via genetic encoded trimethylsilyl 1 H-NMR probe.
Nat Commun, 11, 2020
5WDF
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Crystal structure of 10E8v4-5R+100cF Fab in complex with HIV-1 gp41 peptide
分子名称: 10E8v4-5R+100cF Fab heavy chain, FA10E8v4-5R+100cF FAB light chain, HIV-1 gp41 peptide
著者Kwon, Y.D, Kwong, P.D.
登録日2017-07-05
公開日2018-03-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Surface-Matrix Screening Identifies Semi-specific Interactions that Improve Potency of a Near Pan-reactive HIV-1-Neutralizing Antibody.
Cell Rep, 22, 2018
5Z33
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Crystal structure of Mitogen-activated Protein Kinase Mps1 in Magnaporthe oryzae
分子名称: Mitogen-activated protein kinase
著者Zhou, F, Liu, J.F, Zhang, G.Z.
登録日2018-01-05
公開日2019-03-20
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Crystal structure of Mitogen-activated Protein Kinase Mps1 in Magnaporthe oryzae
To Be Published
7V97
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Arsenic-bound p53 DNA-binding domain mutant V272M
分子名称: ARSENIC, Cellular tumor antigen p53, ZINC ION
著者Lu, M, Xing, Y.F, Wang, Z.Y, Ni, Y, Song, H.X.
登録日2021-08-24
公開日2022-08-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Diverse rescue potencies of p53 mutations to ATO are predetermined by intrinsic mutational properties.
Sci Transl Med, 15, 2023
7WB5
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local structure of hu33 and spike
分子名称: Surface glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, hu33 heavy chain, ...
著者Pulan, L.
登録日2021-12-15
公開日2022-10-26
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献A non-ACE2-blocking neutralizing antibody against Omicron-included SARS-CoV-2 variants.
Signal Transduct Target Ther, 7, 2022
7WBH
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overall structure of hu33 and spike
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Pulan, L.
登録日2021-12-16
公開日2022-10-26
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献A non-ACE2-blocking neutralizing antibody against Omicron-included SARS-CoV-2 variants.
Signal Transduct Target Ther, 7, 2022
7W75
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Crystal structure of the K. lactis Bre1 RBD in complex with Rad6, crystal form I
分子名称: E3 ubiquitin-protein ligase BRE1, Ubiquitin-conjugating enzyme E2 2
著者Shi, M, Zhao, J, Xiang, S.
登録日2021-12-03
公開日2023-03-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for the Rad6 activation by the Bre1 N-terminal domain.
Elife, 12, 2023

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