2HAN
| Structural basis of heterodimeric ecdysteroid receptor interaction with natural response element hsp27 gene promoter | 分子名称: | 5'-D(*CP*AP*AP*GP*GP*GP*TP*TP*CP*AP*AP*TP*GP*CP*AP*CP*TP*TP*GP*T)-3', 5'-D(*GP*AP*CP*AP*AP*GP*TP*GP*CP*AP*TP*TP*GP*AP*AP*CP*CP*CP*TP*T)-3', Ecdysone receptor, ... | 著者 | Jakob, M, Kolodziejczyk, R, Orlowski, M, Krzywda, S, Kowalska, A, Dutko-Gwozdz, J, Gwozdz, T, Kochman, M, Jaskolski, M, Ozyhar, A. | 登録日 | 2006-06-13 | 公開日 | 2007-05-22 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Novel DNA-binding element within the C-terminal extension of the nuclear receptor DNA-binding domain. Nucleic Acids Res., 35, 2007
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6Q4X
| Structure of MPT-2, a GDP-Man-dependent mannosyltransferase from Leishmania mexicana | 分子名称: | SODIUM ION, Uncharacterized protein | 著者 | Sobala, L.F, Males, A, Bastidas, L.M, Ward, T, Sernee, M.F, Ralton, J.E, Nero, T.L, Cobbold, S, Kloehn, J, Viera-Lara, M, Stanton, L, Hanssen, E, Parker, M.W, Williams, S.J, McConville, M.J, Davies, G.J. | 登録日 | 2018-12-06 | 公開日 | 2019-09-18 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | A Family of Dual-Activity Glycosyltransferase-Phosphorylases Mediates Mannogen Turnover and Virulence in Leishmania Parasites. Cell Host Microbe, 26, 2019
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6Q64
| BT1044SeMet E190Q | 分子名称: | Endoglycosidase | 著者 | Basle, A, Paterson, N, Crouch, L, Bolam, D. | 登録日 | 2018-12-10 | 公開日 | 2019-05-08 | 最終更新日 | 2019-09-04 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Complex N-glycan breakdown by gut Bacteroides involves an extensive enzymatic apparatus encoded by multiple co-regulated genetic loci. Nat Microbiol, 4, 2019
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3B2I
| Iodide derivative of human LFABP | 分子名称: | Fatty acid-binding protein, liver, IODIDE ION, ... | 著者 | Sharma, A, Yogavel, M, Sharma, A. | 登録日 | 2011-08-03 | 公開日 | 2012-07-11 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Utility of anion and cation combinations for phasing of protein structures. J.Struct.Funct.Genom., 13, 2012
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6Q7C
| Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with the NVP-BHG712 derivative ATDL11 | 分子名称: | 3-[[4-imidazol-1-yl-6-[(3~{S})-3-oxidanylpiperidin-1-yl]-1,3,5-triazin-2-yl]amino]-4-methyl-~{N}-[3-(trifluoromethyl)phenyl]benzamide, Ephrin type-A receptor 2 | 著者 | Kudlinzki, D, Troester, A, Witt, K, Linhard, V.L, Gande, S.L, Saxena, K, Schwalbe, H. | 登録日 | 2018-12-13 | 公開日 | 2020-01-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.049 Å) | 主引用文献 | Effects of NVP-BHG712 chemical modifications on EPHA2 binding and affinity To Be Published
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3B8D
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2H7S
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1XL5
| HIV-1 Protease in complex with amidhyroxysulfone | 分子名称: | CHLORIDE ION, N-{(1S)-1-(3-BROMOBENZYL)-4-[(4-BROMOPHENYL)SULFONYL]-6-METHYL-2-OXOHEPTYL}-2-(2,6-DIMETHYLPHENOXY)ACETAMIDE, PROTEASE RETROPEPSIN | 著者 | Boettcher, J, Specker, E, Heine, A, Klebe, G. | 登録日 | 2004-09-30 | 公開日 | 2005-06-07 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | An Old Target Revisited: Two New Privileged Skeletons and an Unexpected Binding Mode For HIV-Protease Inhibitors Angew.Chem.Int.Ed.Engl., 44, 2005
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6GGS
| Structure of RIP2 CARD filament | 分子名称: | Receptor-interacting serine/threonine-protein kinase 2 | 著者 | Pellegrini, E, Cusack, S, Desfosses, A, Schoehn, G, Malet, H, Gutsche, I, Sachse, C, Hons, M. | 登録日 | 2018-05-03 | 公開日 | 2018-10-17 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.94 Å) | 主引用文献 | RIP2 filament formation is required for NOD2 dependent NF-kappa B signalling. Nat Commun, 9, 2018
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6QAG
| ERK2 mini-fragment binding | 分子名称: | 1~{H}-1,2,3-triazole, Mitogen-activated protein kinase 1, SULFATE ION | 著者 | O'Reilly, M, Cleasby, A, Davies, T.G, Hall, R, Ludlow, F, Murray, C.W, Tisi, D, Jhoti, H. | 登録日 | 2018-12-19 | 公開日 | 2019-03-27 | 最終更新日 | 2019-05-22 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design. Drug Discov Today, 24, 2019
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1BO4
| CRYSTAL STRUCTURE OF A GCN5-RELATED N-ACETYLTRANSFERASE: SERRATIA MARESCENS AMINOGLYCOSIDE 3-N-ACETYLTRANSFERASE | 分子名称: | COENZYME A, PROTEIN (SERRATIA MARCESCENS AMINOGLYCOSIDE-3-N-ACETYLTRANSFERASE), SPERMIDINE | 著者 | Wolf, E, Vassilev, A, Makino, Y, Sali, A, Nakatani, Y, Burley, S.K. | 登録日 | 1998-08-08 | 公開日 | 1998-10-07 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of a GCN5-related N-acetyltransferase: Serratia marcescens aminoglycoside 3-N-acetyltransferase. Cell(Cambridge,Mass.), 94, 1998
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6QAZ
| Crystal structure of gp41-1 intein | 分子名称: | CITRATE ANION, DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, ... | 著者 | Mikula, K.M, Beyer, H.M, Li, M, Wlodawer, A, Iwai, H. | 登録日 | 2018-12-20 | 公開日 | 2019-11-13 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.02 Å) | 主引用文献 | The crystal structure of the naturally split gp41-1 intein guides the engineering of orthogonal split inteins from cis-splicing inteins. Febs J., 287, 2020
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6Q34
| Dye type peroxidase Aa from Streptomyces lividans: 196 kGy structure | 分子名称: | Deferrochelatase/peroxidase, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Ebrahim, A, Moreno-Chicano, T, Worrall, J.A.R, Strange, R.W, Axford, D, Sherrell, D.A, Appleby, M, Owen, R.L. | 登録日 | 2018-12-03 | 公開日 | 2019-07-31 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Dose-resolved serial synchrotron and XFEL structures of radiation-sensitive metalloproteins. Iucrj, 6, 2019
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6PT1
| Crystal Structure of Class D Beta-lactamase OXA-48 with Meropenem | 分子名称: | (4R,5S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-4,5-d ihydro-1H-pyrrole-2-carboxylic acid, CHLORIDE ION, Class D Carbapenemase OXA-48, ... | 著者 | Akhtar, A, Chen, Y. | 登録日 | 2019-07-14 | 公開日 | 2020-01-22 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural Basis for Substrate Specificity and Carbapenemase Activity of OXA-48 Class D beta-Lactamase. Acs Infect Dis., 6, 2020
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6Q3M
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6GMG
| Structure of a glutamine donor mimicking inhibitory peptide shaped by the catalytic cleft of microbial transglutaminase | 分子名称: | CITRATE ANION, DI(HYDROXYETHYL)ETHER, PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE, ... | 著者 | Schmelz, S, Juettner, N.E, Fuchsbauer, H.L, Scrima, A. | 登録日 | 2018-05-25 | 公開日 | 2018-10-24 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structure of a glutamine donor mimicking inhibitory peptide shaped by the catalytic cleft of microbial transglutaminase. FEBS J., 285, 2018
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3BE6
| Crystal structure of FitE (crystal form 2), a group III periplasmic siderophore binding protein | 分子名称: | CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... | 著者 | Shi, R, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | 登録日 | 2007-11-16 | 公開日 | 2008-10-28 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Trapping open and closed forms of FitE-A group III periplasmic binding protein. Proteins, 75, 2008
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6PUB
| Crystal Structure of the Type B Chloramphenicol Acetyltransferase from Vibrio cholerae in the Complex with Crystal Violet | 分子名称: | CHLORIDE ION, CRYSTAL VIOLET, Chloramphenicol acetyltransferase, ... | 著者 | Kim, Y, Maltseva, N, Kuhn, M, Stam, J, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2019-07-18 | 公開日 | 2019-09-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | Crystal Structure of the Type B Chloramphenicol Acetyltransferase from Vibrio cholerae in the Complex with Crystal Violet To Be Published
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1NOE
| NMR STUDY OF REDUCED HIGH POTENTIAL IRON SULFUR PROTEIN | 分子名称: | HIGH POTENTIAL IRON SULFUR PROTEIN, IRON/SULFUR CLUSTER | 著者 | Bentrop, D, Bertini, I, Capozzi, F, Dikiy, A, Eltis, L, Luchinat, C. | 登録日 | 1996-01-07 | 公開日 | 1996-06-10 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Three-dimensional structure of the reduced C77S mutant of the Chromatium vinosum high-potential iron-sulfur protein through nuclear magnetic resonance: comparison with the solution structure of the wild-type protein. Biochemistry, 35, 1996
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6GFI
| Structure of Human Mesotrypsin in complex with APPI variant T11V/M17R/I18F/F34V | 分子名称: | 1,2-ETHANEDIOL, Amyloid-beta A4 protein, PRSS3 protein | 著者 | Shahar, A, Cohen, I, Radisky, E, Papo, N, Naftaly, S. | 登録日 | 2018-04-30 | 公開日 | 2018-09-12 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Mapping protein selectivity landscapes using multi-target selective screening and next-generation sequencing of combinatorial libraries. Nat Commun, 9, 2018
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6GOE
| KRAS full length G12V GPPNHP | 分子名称: | GTPase KRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | 著者 | Cruz-Migoni, A, Quevedo, C.E, Carr, S.B, Ehebauer, M.T, Phillips, S.V.E, Rabbitts, T.H. | 登録日 | 2018-06-01 | 公開日 | 2019-02-06 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structure-based development of new RAS-effector inhibitors from a combination of active and inactive RAS-binding compounds. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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5DAX
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3QWM
| Crystal Structure of GEP100, the plextrin homology domain of IQ motif and SEC7 domain-containing protein 1 isoform a | 分子名称: | IQ motif and SEC7 domain-containing protein 1 | 著者 | Filippakopoulos, P, Picaud, S, Felletar, I, Feller, S, Janning, M, Sabe, H, Krojer, T, Chaikuad, A, Allerston, C, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2011-02-28 | 公開日 | 2011-04-13 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Crystal Structure of GEP100, the plextrin homology domain of IQ motif and SEC7 domain-containing protein 1 isoform a to be published
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6GON
| Crystal Structure Of Sea Bream Transthyretin in complex with Perfluorooctanoic acid (PFOA). Crystallized in PEG | 分子名称: | Transthyretin, pentadecafluorooctanoic acid | 著者 | Grundstrom, C, Zhang, J, Olofsson, A, Andersson, P.L, Sauer-Eriksson, A.E. | 登録日 | 2018-06-01 | 公開日 | 2018-07-11 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Interspecies Variation between Fish and Human Transthyretins in Their Binding of Thyroid-Disrupting Chemicals. Environ. Sci. Technol., 52, 2018
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6GQ3
| Human asparagine synthetase (ASNS) in complex with 6-diazo-5-oxo-L-norleucine (DON) at 1.85 A resolution | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5-OXO-L-NORLEUCINE, ... | 著者 | Zhu, W, Radadiya, A, Bisson, C, Jin, Y, Nordin, B.E, Imasaki, T, Wenzel, S, Sedelnikova, S.E, Berry, A.H, Nomanbhoy, T.K, Kozarich, J.W, Takagi, Y, Rice, D.W, Richards, N.G.J. | 登録日 | 2018-06-07 | 公開日 | 2019-09-18 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | High-resolution crystal structure of human asparagine synthetase enables analysis of inhibitor binding and selectivity. Commun Biol, 2, 2019
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