6GON

Crystal Structure Of Sea Bream Transthyretin in complex with Perfluorooctanoic acid (PFOA). Crystallized in PEG

Summary for 6GON

Entry DOI	10.2210/pdb6gon/pdb
Descriptor	Transthyretin, pentadecafluorooctanoic acid (3 entities in total)
Functional Keywords	transthyretin, transport protein, thyroxine disrupting chemicals, tdcs, perfluorooctanoic acid, pfoa
Biological source	Sparus aurata (gilthead seabream)
Total number of polymer chains	4
Total formula weight	58648.52
Authors	Grundstrom, C.,Zhang, J.,Olofsson, A.,Andersson, P.L.,Sauer-Eriksson, A.E. (deposition date: 2018-06-01, release date: 2018-07-11, Last modification date: 2024-01-17)
Primary citation	Zhang, J.,Grundstrom, C.,Brannstrom, K.,Iakovleva, I.,Lindberg, M.,Olofsson, A.,Andersson, P.L.,Sauer-Eriksson, A.E. Interspecies Variation between Fish and Human Transthyretins in Their Binding of Thyroid-Disrupting Chemicals. Environ. Sci. Technol., 52:11865-11874, 2018 Cited by PubMed: 30226982 DOI: 10.1021/acs.est.8b03581 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.65 Å)

Structure validation