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5WCH
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Crystal structure of the catalytic domain of human USP9X
分子名称: Probable ubiquitin carboxyl-terminal hydrolase FAF-X, UNKNOWN ATOM OR ION, ZINC ION
著者Dong, A, Zhang, Q, Walker, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC)
登録日2017-06-30
公開日2018-07-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure and activity-based labeling reveal the mechanisms for linkage-specific substrate recognition by deubiquitinase USP9X.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6KJX
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Galectin-13 variant C138S
分子名称: Galactoside-binding soluble lectin 13
著者Su, J.
登録日2019-07-23
公開日2019-10-16
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Galectin-13/placental protein 13: redox-active disulfides as switches for regulating structure, function and cellular distribution.
Glycobiology, 30, 2020
7VOK
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BU of 7vok by Molmil
The Crystal structure of EF-Tu and GDP from Mycobacterium tuberculosis
分子名称: Elongation factor Tu, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Zhan, B.W, Li, J.X.
登録日2021-10-14
公開日2022-10-19
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural insights of the elongation factor EF-Tu complexes in protein translation of Mycobacterium tuberculosis.
Commun Biol, 5, 2022
4NK5
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BU of 4nk5 by Molmil
Crystal structure of FabI-NAD complex from Candidatus Liberibacter asiaticus
分子名称: Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Jiang, L, Gao, Z.Q, Dong, Y.H.
登録日2013-11-12
公開日2014-02-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structures and kinetic properties of enoyl-acyl carrier protein reductase I from Candidatus Liberibacter asiaticus.
Protein Sci., 23, 2014
1FG3
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BU of 1fg3 by Molmil
CRYSTAL STRUCTURE OF L-HISTIDINOL PHOSPHATE AMINOTRANSFERASE COMPLEXED WITH L-HISTIDINOL
分子名称: HISTIDINOL PHOSPHATE AMINOTRANSFERASE, PHOSPHORIC ACID MONO-[2-AMINO-3-(3H-IMIDAZOL-4-YL)-PROPYL]ESTER, PYRIDOXAL-5'-PHOSPHATE
著者Sivaraman, J, Cygler, M.
登録日2000-07-27
公開日2001-08-22
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of histidinol phosphate aminotransferase (HisC) from Escherichia coli, and its covalent complex with pyridoxal-5'-phosphate and l-histidinol phosphate.
J.Mol.Biol., 311, 2001
6XKB
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BU of 6xkb by Molmil
Crystal structure of SR-related and CTD-associated factor 4(SCAF4-CID)with peptide S2,S5p-CTD
分子名称: S2,S5p-CTD peptide, SR-related and CTD-associated factor 4, UNKNOWN ATOM OR ION
著者Zhou, M.Q, Dong, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2020-06-26
公開日2021-01-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural basis for the recognition of the S2, S5-phosphorylated RNA polymerase II CTD by the mRNA anti-terminator protein hSCAF4.
Febs Lett., 596, 2022
4N9G
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BU of 4n9g by Molmil
Crystal Structure of a Computationally Designed RSV-Presenting Epitope Scaffold And Its Elicited Antibody 17HD9
分子名称: Antibody 17HD9, Heavy Chain, Light Chain, ...
著者Carrico, C.T.D, Strong, R.K.
登録日2013-10-21
公開日2014-02-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Proof of principle for epitope-focused vaccine design.
Nature, 507, 2014
7E7Y
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BU of 7e7y by Molmil
Crystal structure of the SARS-CoV-2 S RBD in complex with BD-623 Fab
分子名称: BD-623 Fab H, BD-623 Fab L, Spike protein S1
著者Wei, Y, Xiao, J.
登録日2021-02-28
公開日2021-06-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines.
Cell Res., 31, 2021
7E8C
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BU of 7e8c by Molmil
SARS-CoV-2 S-6P in complex with 9 Fabs
分子名称: 368-2 H, 368-2 L, 604 H, ...
著者Du, S, Xiao, J, Zhang, Z.
登録日2021-03-01
公開日2021-06-09
最終更新日2021-07-14
実験手法ELECTRON MICROSCOPY (3.16 Å)
主引用文献Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines.
Cell Res., 31, 2021
7E8F
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BU of 7e8f by Molmil
SARS-CoV-2 NTD in complex with N9 Fab
分子名称: 368-2 H, 368-2 L, 604 H, ...
著者Du, S, Xiao, J, Zhang, Z.
登録日2021-03-01
公開日2021-06-09
最終更新日2021-07-14
実験手法ELECTRON MICROSCOPY (3.18 Å)
主引用文献Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines.
Cell Res., 31, 2021
7E7X
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BU of 7e7x by Molmil
SARS-CoV-2 Spike Protein N terminal domain in Complex with N11 Fab
分子名称: N11 Fab Light chain, N11 Fab heavy chain, Spike protein S1
著者Zhang, Z, Shuo, D, Xiao, J.
登録日2021-02-28
公開日2021-06-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines.
Cell Res., 31, 2021
7E86
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Crystal structure of the SARS-CoV-2 S RBD in complex with BD-508 Fab
分子名称: BD-508 Fab Heavy Chain, BD-508 Fab Light Chain, Spike protein S1
著者Gao, C, Xiao, J.
登録日2021-03-01
公開日2021-06-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines.
Cell Res., 31, 2021
7E88
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BU of 7e88 by Molmil
Crystal structure of the SARS-CoV-2 S RBD in complex with BD-515 Fab
分子名称: BD-515 Fab Heavy Chain, BD-515 Fab Light Chain, Spike protein S1
著者Gao, C, Wei, Y, Xiao, J.
登録日2021-03-01
公開日2021-06-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.14 Å)
主引用文献Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines.
Cell Res., 31, 2021
3JBZ
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BU of 3jbz by Molmil
Crystal structure of mTOR docked into EM map of dimeric ATM kinase
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Serine/threonine-protein kinase mTOR, ...
著者Lau, W.C.Y.
登録日2015-11-03
公開日2016-11-16
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (28 Å)
主引用文献Structure of the human dimeric ATM kinase.
Cell Cycle, 15, 2016
6WS5
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BU of 6ws5 by Molmil
Rational drug design of phenazopyridine derivatives as novel inhibitors of Rev1-CT
分子名称: 3-[(Z)-(2,3-difluorophenyl)diazenyl]pyridine-2,6-diamine, DNA polymerase zeta catalytic subunit, DNA repair protein REV1, ...
著者McPherson, K.S, Korzhnev, D.M.
登録日2020-04-30
公開日2020-12-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.472 Å)
主引用文献Structure-Based Drug Design of Phenazopyridine Derivatives as Inhibitors of Rev1 Interactions in Translesion Synthesis.
Chemmedchem, 16, 2021
1HN0
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CRYSTAL STRUCTURE OF CHONDROITIN ABC LYASE I FROM PROTEUS VULGARIS AT 1.9 ANGSTROMS RESOLUTION
分子名称: CHONDROITIN ABC LYASE I, SODIUM ION
著者Huang, W, Cygler, M.
登録日2000-12-05
公開日2003-04-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of Proteus vulgaris Chondroitin Sulfate ABC Lyase I at 1.9 Angstroms Resolution
J.Mol.Biol., 328, 2003
1HSI
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CRYSTAL STRUCTURE AT 1.9 ANGSTROMS RESOLUTION OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) II PROTEASE COMPLEXED WITH L-735,524, AN ORALLY BIOAVAILABLE INHIBITOR OF THE HIV PROTEASES
分子名称: HIV-2 PROTEASE
著者Chen, Z.
登録日1995-03-31
公開日1996-04-03
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure at 1.9-A resolution of human immunodeficiency virus (HIV) II protease complexed with L-735,524, an orally bioavailable inhibitor of the HIV proteases.
J.Biol.Chem., 269, 1994
1HSG
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BU of 1hsg by Molmil
CRYSTAL STRUCTURE AT 1.9 ANGSTROMS RESOLUTION OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) II PROTEASE COMPLEXED WITH L-735,524, AN ORALLY BIOAVAILABLE INHIBITOR OF THE HIV PROTEASES
分子名称: HIV-1 PROTEASE, N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE
著者Chen, Z.
登録日1995-03-31
公開日1996-04-03
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure at 1.9-A resolution of human immunodeficiency virus (HIV) II protease complexed with L-735,524, an orally bioavailable inhibitor of the HIV proteases.
J.Biol.Chem., 269, 1994
1F4Q
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CRYSTAL STRUCTURE OF APO GRANCALCIN
分子名称: GRANCALCIN
著者Jia, J, Han, Q, Borregaard, N, Lollike, K, Cygler, M.
登録日2000-06-08
公開日2000-09-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of human grancalcin, a member of the penta-EF-hand protein family.
J.Mol.Biol., 300, 2000
1F4O
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CRYSTAL STRUCTURE OF GRANCALCIN WITH BOUND CALCIUM
分子名称: CALCIUM ION, GRANCALCIN
著者Jia, J, Han, Q, Borregaard, N, Lollike, K, Cygler, M.
登録日2000-06-08
公開日2000-09-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of human grancalcin, a member of the penta-EF-hand protein family.
J.Mol.Biol., 300, 2000
1IM6
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CRYSTAL STRUCTURE OF UNLIGATED HPPK(R82A) FROM E.COLI AT 1.74 ANGSTROM RESOLUTION
分子名称: 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE, CHLORIDE ION
著者Blaszczyk, J, Ji, X.
登録日2001-05-09
公開日2003-04-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Dynamic Roles of Arginine Residues 82 and 92 of Escherichia coli 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase: Crystallographic Studies
Biochemistry, 42, 2003
1FG7
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CRYSTAL STRUCTURE OF L-HISTIDINOL PHOSPHATE AMINOTRANSFERASE WITH PYRIDOXAL-5'-PHOSPHATE
分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, HISTIDINOL PHOSPHATE AMINOTRANSFERASE
著者Sivaraman, J, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2000-07-28
公開日2001-08-22
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of histidinol phosphate aminotransferase (HisC) from Escherichia coli, and its covalent complex with pyridoxal-5'-phosphate and l-histidinol phosphate.
J.Mol.Biol., 311, 2001
1F9H
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CRYSTAL STRUCTURE OF THE TERNARY COMPLEX OF E. COLI HPPK(R92A) WITH MGAMPCPP AND 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN AT 1.50 ANGSTROM RESOLUTION
分子名称: 2-AMINO-6-HYDROXYMETHYL-7,8-DIHYDRO-3H-PTERIDIN-4-ONE, 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE, CHLORIDE ION, ...
著者Blaszczyk, J, Ji, X.
登録日2000-07-10
公開日2003-04-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Dynamic Roles of Arginine Residues 82 and 92 of Escherichia coli 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase: Crystallographic Studies
Biochemistry, 42, 2003
8H7Z
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Cryo-EM structure of SARS-CoV-2 BA.2 RBD in complex with BA7535 fab (local refinement)
分子名称: BA7535 fab, Spike glycoprotein
著者Liu, Z, Yan, A, Gao, Y.
登録日2022-10-21
公開日2023-08-30
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献Identification of a highly conserved neutralizing epitope within the RBD region of diverse SARS-CoV-2 variants.
Nat Commun, 15, 2024
8H7L
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Cryo-EM Structure of SARS-CoV-2 BA.2 Spike protein in complex with BA7535
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BA7535 fab heavt chain, ...
著者Liu, Z, Yan, A, Gao, Y.
登録日2022-10-20
公開日2023-08-30
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (2.44 Å)
主引用文献Identification of a highly conserved neutralizing epitope within the RBD region of diverse SARS-CoV-2 variants.
Nat Commun, 15, 2024

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