4MJV
 
 | | Influenza Neuraminidase in complex with a novel antiviral compound | | 分子名称: | (2E,5S,9R,10S)-10-(acetylamino)-2-imino-4-oxo-9-(pentan-3-yloxy)-1-thia-3-azaspiro[4.5]dec-6-ene-7-carboxylic acid, CALCIUM ION, Neuraminidase | | 著者 | Kerry, P.S. | | 登録日 | 2013-09-04 | | 公開日 | 2014-01-15 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Serendipitous discovery of a potent influenza virus a neuraminidase inhibitor.
Angew.Chem.Int.Ed.Engl., 53, 2014
|
|
4MJU
 | | Influenza Neuraminidase in complex with a novel antiviral compound | | 分子名称: | (5R,9R,10S)-10-(acetylamino)-2-amino-4-oxo-9-(pentan-3-yloxy)-1-thia-3-azaspiro[4.5]deca-2,6-diene-7-carboxylic acid, CALCIUM ION, Neuraminidase | | 著者 | Kerry, P.S. | | 登録日 | 2013-09-04 | | 公開日 | 2014-01-15 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Serendipitous discovery of a potent influenza virus a neuraminidase inhibitor.
Angew.Chem.Int.Ed.Engl., 53, 2014
|
|
8XOK
 | | Cryo-EM structure of human ABCC4 | | 分子名称: | 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, ATP-binding cassette sub-family C member 4, PALMITIC ACID | | 著者 | Zhang, P.F, Liu, Z. | | 登録日 | 2024-01-01 | | 公開日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (2.84 Å) | | 主引用文献 | The ATP-bound inward-open conformation of ABCC4 reveals asymmetric ATP binding for substrate transport.
Febs Lett., 2024
|
|
6CBV
 | | Crystal structure of BRIL bound to an affinity matured synthetic antibody. | | 分子名称: | BRIL, FORMIC ACID, GLYCEROL, ... | | 著者 | Mukherjee, S, Skrobek, B, Kossiakoff, A.A. | | 登録日 | 2018-02-05 | | 公開日 | 2019-02-06 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.872 Å) | | 主引用文献 | Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins.
Nat Commun, 11, 2020
|
|
8X6B
 | | Crystal structure of immune receptor PVRIG in complex with ligand Nectin-2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Nectin-2, Transmembrane protein PVRIG | | 著者 | Hu, S.T, Han, P, Wang, H, Qi, J.X. | | 登録日 | 2023-11-21 | | 公開日 | 2024-04-24 | | 最終更新日 | 2024-07-24 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural basis for the immune recognition and selectivity of the immune receptor PVRIG for ligand Nectin-2.
Structure, 32, 2024
|
|
8XOM
 | | Cryo-EM structure of human ABCC4 in complex with ANP-bound in NBD1 and METHOTREXATE | | 分子名称: | 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, ATP-binding cassette sub-family C member 4, MAGNESIUM ION, ... | | 著者 | Zhang, P.F, Liu, Z. | | 登録日 | 2024-01-01 | | 公開日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | | 主引用文献 | The ATP-bound inward-open conformation of ABCC4 reveals asymmetric ATP binding for substrate transport.
Febs Lett., 2024
|
|
8XOL
 | | Cryo-EM structure of human ABCC4 with ANP bound in NBD1 | | 分子名称: | 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, ATP-binding cassette sub-family C member 4, MAGNESIUM ION, ... | | 著者 | Zhang, P.F, Liu, Z. | | 登録日 | 2024-01-01 | | 公開日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | | 主引用文献 | The ATP-bound inward-open conformation of ABCC4 reveals asymmetric ATP binding for substrate transport.
Febs Lett., 2024
|
|
7T3D
 | |
4ICS
 | | Crystal structure of PepS from Streptococcus pneumoniae in complex with a substrate | | 分子名称: | Aminopeptidase PepS, GLYCINE, TRYPTOPHAN, ... | | 著者 | Lee, S, Kim, K.K, Ta, M.H. | | 登録日 | 2012-12-11 | | 公開日 | 2013-10-23 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Structure-based elucidation of the regulatory mechanism for aminopeptidase activity.
Acta Crystallogr.,Sect.D, 69, 2013
|
|
4ICR
 | | Structural basis for substrate recognition and reaction mechanism of bacterial aminopeptidase peps | | 分子名称: | Aminopeptidase PepS, CACODYLATE ION, ZINC ION | | 著者 | Lee, S, Kim, K.K, Ta, M.H. | | 登録日 | 2012-12-11 | | 公開日 | 2013-10-23 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | Structure-based elucidation of the regulatory mechanism for aminopeptidase activity.
Acta Crystallogr.,Sect.D, 69, 2013
|
|
4ICQ
 | |
1T4S
 | | arginase-L-valine complex | | 分子名称: | Arginase 1, MANGANESE (II) ION, VALINE | | 著者 | Cama, E, Pethe, S, Boucher, J.-L, Shoufa, H, Emig, F.A, Ash, D.E, Viola, R.E, Mansuy, D, Christianson, D.W. | | 登録日 | 2004-04-30 | | 公開日 | 2004-10-12 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Inhibitor coordination interactions in the binuclear manganese cluster of arginase
Biochemistry, 43, 2004
|
|
1T4R
 | | arginase-descarboxy-nor-NOHA complex | | 分子名称: | 3-{[(E)-AMINO(HYDROXYIMINO)METHYL]AMINO}PROPAN-1-AMINIUM, Arginase 1, MANGANESE (II) ION | | 著者 | Cama, E, Pethe, S, Boucher, J.-L, Shoufa, H, Emig, F.A, Ash, D.E, Viola, R.E, Mansuy, D, Christianson, D.W. | | 登録日 | 2004-04-30 | | 公開日 | 2005-04-12 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Inhibitor coordination interactions in the binuclear manganese cluster of arginase
Biochemistry, 43, 2004
|
|
1T4T
 | | arginase-dinor-NOHA complex | | 分子名称: | 3-{[(E)-AMINO(HYDROXYIMINO)METHYL]AMINO}ALANINE, Arginase 1, MANGANESE (II) ION | | 著者 | Cama, E, Pethe, S, Boucher, J.-L, Shoufa, H, Emig, F.A, Ash, D.E, Viola, R.E, Mansuy, D, Christianson, D.W. | | 登録日 | 2004-04-30 | | 公開日 | 2005-04-12 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Inhibitor coordination interactions in the binuclear manganese cluster of arginase
Biochemistry, 43, 2004
|
|
6IIV
 | | Crystal structure of the human thromboxane A2 receptor bound to daltroban | | 分子名称: | 2-[4-[2-[(4-chlorophenyl)sulfonylamino]ethyl]phenyl]ethanoic acid, CHOLESTEROL, GLYCEROL, ... | | 著者 | Fan, H, Zhao, Q, Wu, B. | | 登録日 | 2018-10-07 | | 公開日 | 2018-12-19 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural basis for ligand recognition of the human thromboxane A2receptor.
Nat. Chem. Biol., 15, 2019
|
|
6ITA
 | | Crystal structure of intracellular B30.2 domain of BTN3A1 mutant | | 分子名称: | Butyrophilin subfamily 3 member A1 | | 著者 | Yang, Y.Y, Liu, W.D, Cai, N.N, Chen, C.C, Guo, R.T, Zhang, Y.H. | | 登録日 | 2018-11-20 | | 公開日 | 2019-04-03 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | A Structural Change in Butyrophilin upon Phosphoantigen Binding Underlies Phosphoantigen-Mediated V gamma 9V delta 2 T Cell Activation.
Immunity, 50, 2019
|
|
6ISM
 | | Crystal structure of intracellular B30.2 domain of BTN3A1 mutant | | 分子名称: | Butyrophilin subfamily 3 member A1 | | 著者 | Yang, Y.Y, Liu, W.D, Cai, N.N, Chen, C.C, Guo, R.T, Zhang, Y.H. | | 登録日 | 2018-11-16 | | 公開日 | 2019-04-03 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | A Structural Change in Butyrophilin upon Phosphoantigen Binding Underlies Phosphoantigen-Mediated V gamma 9V delta 2 T Cell Activation.
Immunity, 50, 2019
|
|
6J0L
 | | Crystal structure of intracellular B30.2 domain of BTN3A3 mutant in complex with sulfate ion | | 分子名称: | Butyrophilin subfamily 3 member A3, SULFATE ION | | 著者 | Yang, Y.Y, Liu, W.D, Cai, N.N, Chen, C.C, Guo, R.T, Zhang, Y.H. | | 登録日 | 2018-12-24 | | 公開日 | 2019-04-03 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | A Structural Change in Butyrophilin upon Phosphoantigen Binding Underlies Phosphoantigen-Mediated V gamma 9V delta 2 T Cell Activation.
Immunity, 50, 2019
|
|
6J0K
 | | Crystal structure of intracellular B30.2 domain of BTN3A3 mutant in complex with HMBPP | | 分子名称: | (2E)-4-hydroxy-3-methylbut-2-en-1-yl trihydrogen diphosphate, Butyrophilin subfamily 3 member A3 | | 著者 | Yang, Y.Y, Liu, W.D, Cai, N.N, Chen, C.C, Guo, R.T, Zhang, Y.H. | | 登録日 | 2018-12-24 | | 公開日 | 2019-04-03 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A Structural Change in Butyrophilin upon Phosphoantigen Binding Underlies Phosphoantigen-Mediated V gamma 9V delta 2 T Cell Activation.
Immunity, 50, 2019
|
|
6J0G
 | | Crystal structure of intracellular B30.2 domain of BTN3A3 mutant in complex with HMBPP | | 分子名称: | (2E)-4-hydroxy-3-methylbut-2-en-1-yl trihydrogen diphosphate, Butyrophilin subfamily 3 member A3 | | 著者 | Yang, Y.Y, Liu, W.D, Cai, N.N, Chen, C.C, Guo, R.T, Zhang, Y.H. | | 登録日 | 2018-12-24 | | 公開日 | 2019-04-03 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | A Structural Change in Butyrophilin upon Phosphoantigen Binding Underlies Phosphoantigen-Mediated V gamma 9V delta 2 T Cell Activation.
Immunity, 50, 2019
|
|
1TA1
 | | H141C mutant of rat liver arginase I | | 分子名称: | Arginase 1, GLYCEROL, MANGANESE (II) ION | | 著者 | Cama, E, Cox, J.D, Ash, D.E, Christianson, D.W. | | 登録日 | 2004-05-19 | | 公開日 | 2005-08-16 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Probing the role of the hyper-reactive histidine residue of arginase.
Arch.Biochem.Biophys., 444, 2005
|
|
1TBH
 | | H141D mutant of rat liver arginase I | | 分子名称: | Arginase 1, MANGANESE (II) ION | | 著者 | Cama, E, Cox, J.D, Ash, D.E, Christianson, D.W. | | 登録日 | 2004-05-20 | | 公開日 | 2005-08-16 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Probing the role of the hyper-reactive histidine residue of arginase.
Arch.Biochem.Biophys., 444, 2005
|
|
6ISS
 | | Lignin peroxidase H8 triple mutant S49C/A67C/H239 | | 分子名称: | CALCIUM ION, Ligninase H8, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Seo, H, Son, H, Kim, K.-J. | | 登録日 | 2018-11-19 | | 公開日 | 2019-11-20 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | Extra disulfide and ionic salt bridge improves the thermostability of lignin peroxidase H8 under acidic condition
Enzyme.Microb.Technol., 148, 2021
|
|
7OBQ
 | | SRP-SR at the distal site conformation | | 分子名称: | EM14S01-3B_G0054400.mRNA.1.CDS.1, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Jomaa, A, Ban, N. | | 登録日 | 2021-04-23 | | 公開日 | 2021-07-21 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Molecular mechanism of cargo recognition and handover by the mammalian signal recognition particle.
Cell Rep, 36, 2021
|
|
7OBR
 | | RNC-SRP early complex | | 分子名称: | 28S rRNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | | 著者 | Jomaa, A, Ban, N. | | 登録日 | 2021-04-23 | | 公開日 | 2021-07-21 | | 最終更新日 | 2021-07-28 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Molecular mechanism of cargo recognition and handover by the mammalian signal recognition particle.
Cell Rep, 36, 2021
|
|
