3UMZ
| Crystal Structure of the human MDC1 FHA Domain | 分子名称: | Mediator of DNA damage checkpoint protein 1 | 著者 | Luo, S, Ye, K. | 登録日 | 2011-11-15 | 公開日 | 2012-01-25 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structural mechanism of the phosphorylation-dependent dimerization of the MDC1 forkhead-associated domain Nucleic Acids Res., 40, 2012
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4KBK
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8WI2
| RD-hMRP5-inward open | 分子名称: | ATP-binding cassette sub-family C member 5, CYS-GLN-ASP-ALA-LEU-GLU-THR-ALA-ALA-ARG-ALA-GLU-GLY-LEU-SER-LEU-ASP-ALA-SER | 著者 | Liu, Z.M, Huang, Y. | 登録日 | 2023-09-24 | 公開日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (4.06 Å) | 主引用文献 | Inhibition and transport mechanisms of the ABC transporter hMRP5. Nat Commun, 15, 2024
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8VVK
| CCHFV GP38 bound to ADI-46143 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADI-46143 Fab Heavy Chain, ADI-46143 Fab Light Chain, ... | 著者 | Hjorth, C.K, McLellan, J.S. | 登録日 | 2024-01-31 | 公開日 | 2024-07-17 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Crimean-Congo hemorrhagic fever survivors elicit protective non-neutralizing antibodies that target 11 overlapping regions on glycoprotein GP38. Cell Rep, 43, 2024
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8WI3
| ND-hMRP5-inward open | 分子名称: | ATP-binding cassette sub-family C member 5 | 著者 | Liu, Z.M, Huang, Y. | 登録日 | 2023-09-24 | 公開日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | 主引用文献 | Inhibition and transport mechanisms of the ABC transporter hMRP5. Nat Commun, 15, 2024
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8VVL
| CCHFV GP38 bound to c13G8 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | 著者 | Hjorth, C.K, Mishra, A.K, McLellan, J.S. | 登録日 | 2024-01-31 | 公開日 | 2024-07-17 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crimean-Congo hemorrhagic fever survivors elicit protective non-neutralizing antibodies that target 11 overlapping regions on glycoprotein GP38. Cell Rep, 43, 2024
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8WI4
| m6-hMRP5 inward open | 分子名称: | ATP-binding cassette sub-family C member 5 | 著者 | Liu, Z.M, Huang, Y. | 登録日 | 2023-09-24 | 公開日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Inhibition and transport mechanisms of the ABC transporter hMRP5. Nat Commun, 15, 2024
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7VWY
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8VWW
| CCHFV GP38 bound to ADI-46152 and ADI-58048 Fabs | 分子名称: | ADI-46152 Fab Heavy Chain, ADI-46152 Fab Light Chain, ADI-58048 Fab Heavy Chain, ... | 著者 | Hjorth, C.K, McLellan, J.S. | 登録日 | 2024-02-02 | 公開日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Crimean-Congo hemorrhagic fever survivors elicit protective non-neutralizing antibodies that target 11 overlapping regions on glycoprotein GP38. Cell Rep, 43, 2024
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8WI0
| wt-hMRP5 inward-open | 分子名称: | ATP-binding cassette sub-family C member 5 | 著者 | Liu, Z.M, Huang, Y. | 登録日 | 2023-09-24 | 公開日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | 主引用文献 | Inhibition and transport mechanisms of the ABC transporter hMRP5. Nat Commun, 15, 2024
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8WI5
| M5PI-bound hMRP5 | 分子名称: | ATP-binding cassette sub-family C member 5 | 著者 | Liu, Z.M, Huang, Y. | 登録日 | 2023-09-24 | 公開日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | 主引用文献 | Inhibition and transport mechanisms of the ABC transporter hMRP5. Nat Commun, 15, 2024
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8WRJ
| glycosyltransferase UGT74AN3 | 分子名称: | 5-[(1R,2S,4R,6R,7R,10S,11S,14S,16R)-14-hydroxy-7,11-dimethyl-3-oxapentacyclo[8.8.0.02,4.02,7.011,16]octadecan-6-yl]pyran-2-one, Glycosyltransferase, URIDINE-5'-DIPHOSPHATE | 著者 | Huang, W, Long, F. | 登録日 | 2023-10-15 | 公開日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Substrate Promiscuity, Crystal Structure, and Application of a Plant UDP-Glycosyltransferase UGT74AN3 Acs Catalysis, 14, 2024
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8WRK
| glycosyltransferase UGT74AN3 | 分子名称: | Glycosyltransferase, PICEATANNOL, URIDINE-5'-DIPHOSPHATE | 著者 | Huang, W, Long, F. | 登録日 | 2023-10-15 | 公開日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Substrate Promiscuity, Crystal Structure, and Application of a Plant UDP-Glycosyltransferase UGT74AN3 Acs Catalysis, 14, 2024
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8XLM
| Structure of the SARS-CoV-2 EG.5.1 spike glycoprotein in complex with ACE2 (1-up state) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | 著者 | Nomai, T, Anraku, Y, Kita, S, Hashiguchi, T, Maenaka, K. | 登録日 | 2023-12-26 | 公開日 | 2024-05-01 | 最終更新日 | 2024-09-25 | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | 主引用文献 | Virological characteristics of the SARS-CoV-2 Omicron EG.5.1 variant. Microbiol Immunol, 68, 2024
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8XLN
| Structure of the SARS-CoV-2 EG.5.1 spike RBD in complex with ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | 著者 | Nomai, T, Anraku, Y, Kita, S, Hashiguchi, T, Maenaka, K. | 登録日 | 2023-12-26 | 公開日 | 2024-05-01 | 最終更新日 | 2024-09-25 | 実験手法 | ELECTRON MICROSCOPY (3.78 Å) | 主引用文献 | Virological characteristics of the SARS-CoV-2 Omicron EG.5.1 variant. Microbiol Immunol, 68, 2024
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9INR
| Crystal structure of PIN1 in complex with inhibitor C3 | 分子名称: | 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, SULFATE ION, ... | 著者 | Zhang, L.Y. | 登録日 | 2024-07-08 | 公開日 | 2024-09-25 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Re-Evaluating PIN1 as a Therapeutic Target in Oncology Using Neutral Inhibitors and PROTACs. J.Med.Chem., 67, 2024
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7BTK
| E.coli beta-galactosidase (E537Q) in complex with fluorescent probe KSA01 | 分子名称: | 4-[[2-[(E)-2-[4-[(2S,3R,4S,5R,6R)-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxyphenyl]ethenyl]-3,3-dimethyl-2H-indol-1-yl]methyl]benzoic acid, Beta-galactosidase, DIMETHYL SULFOXIDE, ... | 著者 | Chen, X, Hu, Y.L, Liu, Q.M, Gao, Y, Yuan, R, Guo, Y. | 登録日 | 2020-04-01 | 公開日 | 2021-03-03 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Two-Dimensional Design Strategy to Construct Smart Fluorescent Probes for the Precise Tracking of Senescence. Angew.Chem.Int.Ed.Engl., 60, 2021
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7BRS
| E.coli beta-galactosidase (E537Q) in complex with fluorescent probe KSA02 | 分子名称: | 8-[2-[(E)-2-[4-[(2S,3R,4S,5R,6R)-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxyphenyl]ethenyl]-3,3-dimethyl-indol-1-ium-1-yl]octanoic acid, Beta-galactosidase, DIMETHYL SULFOXIDE, ... | 著者 | Chen, X, Hu, Y.L, Gao, Y, Yuan, R, Guo, Y. | 登録日 | 2020-03-30 | 公開日 | 2021-03-03 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | 主引用文献 | Two-Dimensional Design Strategy to Construct Smart Fluorescent Probes for the Precise Tracking of Senescence. Angew.Chem.Int.Ed.Engl., 60, 2021
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4XLY
| The complex structure of KS-D75C with substrate CPP | 分子名称: | (2E)-3-methyl-5-[(1R,4aR,8aR)-5,5,8a-trimethyl-2-methylidenedecahydronaphthalen-1-yl]pent-2-en-1-yl trihydrogen diphosphate, Uncharacterized protein blr2150 | 著者 | Hu, Y, Zheng, Y, Ko, T.P, Liu, W, Guo, R.T. | 登録日 | 2015-01-14 | 公開日 | 2015-02-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Structure, function and inhibition of ent-kaurene synthase from Bradyrhizobium japonicum. Sci Rep, 4, 2014
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7VMB
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6DXI
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6E62
| Crystal structure of malaria transmission-blocking antigen Pfs48/45 6C in complex with antibody 85RF45.1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 85RF45.1 Fab heavy chain, 85RF45.1 Fab light chain, ... | 著者 | Kundu, P, Semesi, A, Julien, J.P. | 登録日 | 2018-07-23 | 公開日 | 2018-11-28 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural delineation of potent transmission-blocking epitope I on malaria antigen Pfs48/45. Nat Commun, 9, 2018
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4XLX
| Crystal structure of BjKS from Bradyrhizobium japonicum | 分子名称: | Uncharacterized protein blr2150 | 著者 | Hu, Y, Zheng, Y, Ko, T.P, Liu, W, Guo, R.T. | 登録日 | 2015-01-14 | 公開日 | 2015-02-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure, function and inhibition of ent-kaurene synthase from Bradyrhizobium japonicum. Sci Rep, 4, 2014
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6E63
| Crystal structure of malaria transmission-blocking antigen Pfs48/45 6C in complex with antibody TB31F | 分子名称: | GLYCEROL, Pf48/45, TB31F Fab heavy chain, ... | 著者 | Kundu, P, Semesi, A, Julien, J.P. | 登録日 | 2018-07-23 | 公開日 | 2018-11-28 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural delineation of potent transmission-blocking epitope I on malaria antigen Pfs48/45. Nat Commun, 9, 2018
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7W5Y
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