6OA1
| Structure of human PARG complexed with JA2120 | 分子名称: | 1,3-dimethyl-8-{[2-(morpholin-4-yl)ethyl]sulfanyl}-3,7-dihydro-1H-purine-2,6-dione, Poly(ADP-ribose) glycohydrolase | 著者 | Stegeman, R.A, Jones, D.E, Ellenberger, T, Kim, I.K, Tainer, J.A. | 登録日 | 2019-03-15 | 公開日 | 2019-12-25 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Selective small molecule PARG inhibitor causes replication fork stalling and cancer cell death. Nat Commun, 10, 2019
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6OBS
| PP1 Y134K | 分子名称: | GLYCEROL, MANGANESE (II) ION, PHOSPHATE ION, ... | 著者 | Choy, M.S, Moon, T.M, Bray, J.A, Archuleta, T.L, Shi, W, Peti, W, Page, R. | 登録日 | 2019-03-21 | 公開日 | 2019-09-18 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.803 Å) | 主引用文献 | SDS22 selectively recognizes and traps metal-deficient inactive PP1. Proc.Natl.Acad.Sci.USA, 116, 2019
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8THR
| Structure of the human vesicular monoamine transporter 2 (VMAT2) bound to tetrabenazine in an occluded conformation | 分子名称: | (3S,5R,11bS)-9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one, fluorescent protein mVenus,Synaptic vesicular amine transporter,GFP nano body,Synaptic vesicular amine transporter,Synaptic vesicular amine transporter | 著者 | Dalton, M.P, Coleman, J.A. | 登録日 | 2023-07-17 | 公開日 | 2023-10-25 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | 主引用文献 | Structural mechanisms for VMAT2 inhibition by tetrabenazine. Elife, 12, 2024
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3NOD
| MURINE INDUCIBLE NITRIC OXIDE SYNTHASE OXYGENASE DIMER (DELTA 65) WITH TETRAHYDROBIOPTERIN AND PRODUCT ANALOGUE L-THIOCITRULLINE | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, L-THIOCITRULLINE, NITRIC OXIDE SYNTHASE, ... | 著者 | Crane, B.R, Arvai, A.S, Getzoff, E.D, Stuehr, D.J, Tainer, J.A. | 登録日 | 1998-03-06 | 公開日 | 1999-03-23 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure of nitric oxide synthase oxygenase dimer with pterin and substrate. Science, 279, 1998
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4CYP
| Leishmania major N-myristoyltransferase in complex with a pyrrolidine inhibitor. | 分子名称: | (3R)-4-(4-chlorophenyl)-1-[(3S,4R)-3-(4-chlorophenyl)-4-(hydroxymethyl)pyrrolidin-1-yl]-3-hydroxybutan-1-one, GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, MAGNESIUM ION, ... | 著者 | Hutton, J.A, Goncalves, V, Brannigan, J.A, Paape, D, Waugh, T, Roberts, S.M, Bell, A.S, Wilkinson, A.J, Smith, D.F, Leatherbarrow, R.J, Tate, E.W. | 登録日 | 2014-04-14 | 公開日 | 2014-10-22 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Structure-Based Design of Potent and Selective Leishmania N- Myristoyltransferase Inhibitors. J.Med.Chem., 57, 2014
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2EFW
| Crystal structure of the RTP:nRB complex from Bacillus subtilis | 分子名称: | DNA (5'-D(*DCP*DT*DAP*DTP*DGP*DTP*DAP*DCP*DCP*DAP*DAP*DAP*DTP*DGP*DTP*DTP*DCP*DAP*DGP*DTP*DC)-3'), DNA (5'-D(*DGP*DAP*DCP*DTP*DGP*DAP*DAP*DCP*DAP*DTP*DTP*DTP*DGP*DGP*DTP*DAP*DCP*DAP*DTP*DAP*DG)-3'), Replication termination protein | 著者 | Vivian, J.P, Porter, C.J, Wilce, J.A, Wilce, M.C.J. | 登録日 | 2007-02-26 | 公開日 | 2008-02-26 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | An asymmetric structure of the Bacillus subtilis replication terminator protein in complex with DNA J.Mol.Biol., 370, 2007
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8U1C
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8U50
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6PAX
| CRYSTAL STRUCTURE OF THE HUMAN PAX-6 PAIRED DOMAIN-DNA COMPLEX REVEALS A GENERAL MODEL FOR PAX PROTEIN-DNA INTERACTIONS | 分子名称: | 26 NUCLEOTIDE DNA, HOMEOBOX PROTEIN PAX-6 | 著者 | Xu, H.E, Rould, M.A, Xu, W, Epstein, J.A, Maas, R.L, Pabo, C.O. | 登録日 | 1999-04-22 | 公開日 | 1999-07-13 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of the human Pax6 paired domain-DNA complex reveals specific roles for the linker region and carboxy-terminal subdomain in DNA binding. Genes Dev., 13, 1999
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8U1S
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6PBK
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8U1Q
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8U51
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8U4Z
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6OZZ
| N terminally deleted GapR crystal structure from C. crescentus | 分子名称: | UPF0335 protein CC_3319 | 著者 | Tarry, M, Harmel, C, Taylor, J.A, Marczynski, G.T, Schmeing, T.M. | 登録日 | 2019-05-16 | 公開日 | 2019-11-27 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.304 Å) | 主引用文献 | Structures of GapR reveal a central channel which could accommodate B-DNA. Sci Rep, 9, 2019
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6P58
| Dark and Steady State-Illuminated Crystal Structure of Cyanobacteriochrome Receptor PixJ at 150K | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, Methyl-accepting chemotaxis protein, ... | 著者 | Clinger, J.A, Miller, M.D, Buirgie, E.S, Vierstra, R.D, Phillips Jr, G.N. | 登録日 | 2019-05-29 | 公開日 | 2019-12-18 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (1.499 Å) | 主引用文献 | Photoreversible interconversion of a phytochrome photosensory module in the crystalline state. Proc.Natl.Acad.Sci.USA, 117, 2020
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6O4J
| Amyloid Beta KLVFFAENVGS 16-26 D23N Iowa mutation | 分子名称: | Amyloid-beta precursor protein | 著者 | Griner, S.L, Sawaya, M.R, Rodriguez, J.A, Cascio, D, Gonen, T. | 登録日 | 2019-02-28 | 公開日 | 2019-10-30 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.402 Å) | 主引用文献 | Structure based inhibitors of Amyloid Beta core suggest a common interface with Tau. Elife, 8, 2019
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6OBP
| Reconstituted PP1 holoenzyme | 分子名称: | CHLORIDE ION, MANGANESE (II) ION, PHOSPHATE ION, ... | 著者 | Choy, M.S, Moon, T.M, Bray, J.A, Archuleta, T.L, Shi, W, Peti, W, Page, R. | 登録日 | 2019-03-21 | 公開日 | 2019-09-18 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | SDS22 selectively recognizes and traps metal-deficient inactive PP1. Proc.Natl.Acad.Sci.USA, 116, 2019
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6OZW
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1F93
| CRYSTAL STRUCTURE OF A COMPLEX BETWEEN THE DIMERIZATION DOMAIN OF HNF-1 ALPHA AND THE COACTIVATOR DCOH | 分子名称: | DIMERIZATION COFACTOR OF HEPATOCYTE NUCLEAR FACTOR 1-ALPHA, HEPATOCYTE NUCLEAR FACTOR 1-ALPHA | 著者 | Rose, R.B, Bayle, J.H, Endrizzi, J.A, Cronk, J.D, Crabtree, G.R, Alber, T. | 登録日 | 2000-07-06 | 公開日 | 2000-09-20 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis of dimerization, coactivator recognition and MODY3 mutations in HNF-1alpha. Nat.Struct.Biol., 7, 2000
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8UPI
| Structure of a periplasmic peptide binding protein from Mesorhizobium sp. AP09 bound to aminoserine | 分子名称: | 1,2-ETHANEDIOL, AMINOSERINE, CALCIUM ION, ... | 著者 | Frkic, R.L, Smith, O.B, Rahman, M, Kaczmarski, J.A, Jackson, C.J. | 登録日 | 2023-10-22 | 公開日 | 2023-11-08 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Identification and Characterization of a Bacterial Periplasmic Solute Binding Protein That Binds l-Amino Acid Amides. Biochemistry, 63, 2024
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6OZX
| Wild type GapR crystal structure 1 from C. crescentus | 分子名称: | UPF0335 protein CC_3319 | 著者 | Tarry, M, Harmel, C, Taylor, J.A, Marczynski, G.T, Schmeing, T.M. | 登録日 | 2019-05-16 | 公開日 | 2019-11-27 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.851 Å) | 主引用文献 | Structures of GapR reveal a central channel which could accommodate B-DNA. Sci Rep, 9, 2019
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8UGQ
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2BZB
| NMR Solution Structure of a protein aspartic acid phosphate phosphatase from Bacillus Anthracis | 分子名称: | CONSERVED DOMAIN PROTEIN | 著者 | Grenha, R, Rzechorzek, N.J, Brannigan, J.A, Ab, E, Folkers, G.E, De Jong, R.N, Diercks, T, Wilkinson, A.J, Kaptein, R, Wilson, K.S. | 登録日 | 2005-08-14 | 公開日 | 2006-09-25 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural characterization of Spo0E-like protein-aspartic acid phosphatases that regulate sporulation in bacilli. J. Biol. Chem., 281, 2006
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6OZY
| Wild type GapR crystal structure 2 from C. crescentus | 分子名称: | CADMIUM ION, UPF0335 protein CC_3319 | 著者 | Tarry, M, Harmel, C, Taylor, J.A, Marczynski, G.T, Schmeing, T.M. | 登録日 | 2019-05-16 | 公開日 | 2019-11-27 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.014 Å) | 主引用文献 | Structures of GapR reveal a central channel which could accommodate B-DNA. Sci Rep, 9, 2019
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