6MTP
| Crystal structure of VRC42.04 Fab in complex with gp41 peptide | 分子名称: | Antibody VRC42.04 Fab heavy chain, Antibody VRC42.04 Fab light chain, RV217 founder virus gp41 peptide | 著者 | Kwon, Y.D, Druz, A, Law, W.H, Peng, D, Zhang, B, Doria-Rose, N.A, Kwong, P.D. | 登録日 | 2018-10-21 | 公開日 | 2019-03-27 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.036 Å) | 主引用文献 | Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual. Immunity, 50, 2019
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5XMY
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5WTH
| Cryo-EM structure for Hepatitis A virus complexed with FAB | 分子名称: | FAB Heavy Chain, FAB Light Chain, Polyprotein, ... | 著者 | Wang, X, Zhu, L, Dang, M, Hu, Z, Gao, Q, Yuan, S, Sun, Y, Zhang, B, Ren, J, Walter, T.S, Wang, J, Fry, E.E, Stuart, D.I, Rao, Z. | 登録日 | 2016-12-12 | 公開日 | 2017-01-25 | 最終更新日 | 2019-11-06 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Potent neutralization of hepatitis A virus reveals a receptor mimic mechanism and the receptor recognition site Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5WTE
| Cryo-EM structure for Hepatitis A virus full particle | 分子名称: | VP1, VP2, VP3 | 著者 | Wang, X, Zhu, L, Dang, M, Hu, Z, Gao, Q, Yuan, S, Sun, Y, Zhang, B, Ren, J, Walter, T.S, Wang, J, Fry, E.E, Stuart, D.I, Rao, Z. | 登録日 | 2016-12-11 | 公開日 | 2017-01-25 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Potent neutralization of hepatitis A virus reveals a receptor mimic mechanism and the receptor recognition site Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5WTG
| Crystal structure of the Fab fragment of anti-HAV antibody R10 | 分子名称: | FAB Heavy chain, FAB Light chain | 著者 | Wang, X, Zhu, L, Dang, M, Hu, Z, Gao, Q, Yuan, S, Sun, Y, Zhang, B, Ren, J, Walter, T.S, Wang, J, Fry, E.E, Stuart, D.I, Rao, Z. | 登録日 | 2016-12-11 | 公開日 | 2017-01-25 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.907 Å) | 主引用文献 | Potent neutralization of hepatitis A virus reveals a receptor mimic mechanism and the receptor recognition site Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5YC4
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5YC3
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5WTF
| Cryo-EM structure for Hepatitis A virus empty particle | 分子名称: | VP0, VP1, VP3 | 著者 | Wang, X, Zhu, L, Dang, M, Hu, Z, Gao, Q, Yuan, S, Sun, Y, Zhang, B, Ren, J, Walter, T.S, Wang, J, Fry, E.E, Stuart, D.I, Rao, Z. | 登録日 | 2016-12-11 | 公開日 | 2017-01-25 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Potent neutralization of hepatitis A virus reveals a receptor mimic mechanism and the receptor recognition site Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5Y20
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5LUS
| Structures of DHBN domain of Pelecanus crispus BLM helicase | 分子名称: | BLM helicase | 著者 | Shi, J, Chen, W.-F, Zhang, B, Fan, S.-H, Ai, X, Liu, N.-N, Rety, S, Xi, X.-G. | 登録日 | 2016-09-09 | 公開日 | 2017-03-01 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.433 Å) | 主引用文献 | A helical bundle in the N-terminal domain of the BLM helicase mediates dimer and potentially hexamer formation. J. Biol. Chem., 292, 2017
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5MK5
| Structures of DHBN domain of human BLM helicase | 分子名称: | Bloom syndrome protein, IODIDE ION, POTASSIUM ION | 著者 | Shi, J, Chen, W.-F, Zhang, B, Fan, S.-H, Ai, X, Liu, N.-N, Rety, S, Xi, X.-G. | 登録日 | 2016-12-02 | 公開日 | 2017-03-01 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | A helical bundle in the N-terminal domain of the BLM helicase mediates dimer and potentially hexamer formation. J. Biol. Chem., 292, 2017
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5LUT
| Structures of DHBN domain of Gallus gallus BLM helicase | 分子名称: | BLM helicase, PHOSPHATE ION | 著者 | Shi, J, Chen, W.-F, Zhang, B, Fan, S.-H, Ai, X, Liu, N.-N, Rety, S, Xi, X.-G. | 登録日 | 2016-09-09 | 公開日 | 2017-03-01 | 最終更新日 | 2017-04-19 | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | 主引用文献 | A helical bundle in the N-terminal domain of the BLM helicase mediates dimer and potentially hexamer formation. J. Biol. Chem., 292, 2017
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5LUP
| Structures of DHBN domain of human BLM helicase | 分子名称: | BLM protein, PHOSPHATE ION, POTASSIUM ION | 著者 | Shi, J, Chen, W.-F, Zhang, B, Fan, S.-H, Ai, X, Liu, N.-N, Rety, S, Xi, X.-G. | 登録日 | 2016-09-09 | 公開日 | 2017-03-01 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.032 Å) | 主引用文献 | A helical bundle in the N-terminal domain of the BLM helicase mediates dimer and potentially hexamer formation. J. Biol. Chem., 292, 2017
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8HPM
| LpqY-SugABC in state 2 | 分子名称: | ABC sugar transporter, permease component, ABC transporter, ... | 著者 | Liang, J, Yang, X, Zhang, B, Rao, Z, Liu, F. | 登録日 | 2022-12-12 | 公開日 | 2023-09-06 | 最終更新日 | 2023-10-18 | 実験手法 | ELECTRON MICROSCOPY (3.82 Å) | 主引用文献 | Structural insights into trehalose capture and translocation by mycobacterial LpqY-SugABC. Structure, 31, 2023
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8HPN
| LpqY-SugABC in state 3 | 分子名称: | ABC sugar transporter, permease component, ABC transporter, ... | 著者 | Liang, J, Yang, X, Zhang, B, Rao, Z, Liu, F. | 登録日 | 2022-12-12 | 公開日 | 2023-09-06 | 最終更新日 | 2023-10-18 | 実験手法 | ELECTRON MICROSCOPY (4.55 Å) | 主引用文献 | Structural insights into trehalose capture and translocation by mycobacterial LpqY-SugABC. Structure, 31, 2023
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8HPS
| LpqY-SugABC in state 5 | 分子名称: | ABC sugar transporter, permease component, ABC transporter, ... | 著者 | Liang, J, Yang, X, Zhang, B, Rao, Z, Liu, F. | 登録日 | 2022-12-12 | 公開日 | 2023-09-06 | 最終更新日 | 2023-10-18 | 実験手法 | ELECTRON MICROSCOPY (3.51 Å) | 主引用文献 | Structural insights into trehalose capture and translocation by mycobacterial LpqY-SugABC. Structure, 31, 2023
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8HPL
| LpqY-SugABC in state 1 | 分子名称: | ABC sugar transporter, permease component, ABC transporter, ... | 著者 | Liang, J, Yang, X, Zhang, B, Rao, Z, Liu, F. | 登録日 | 2022-12-12 | 公開日 | 2023-09-06 | 最終更新日 | 2023-10-18 | 実験手法 | ELECTRON MICROSCOPY (4.29 Å) | 主引用文献 | Structural insights into trehalose capture and translocation by mycobacterial LpqY-SugABC. Structure, 31, 2023
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8HPR
| LpqY-SugABC in state 4 | 分子名称: | ABC sugar transporter, permease component, ABC transporter, ... | 著者 | Liang, J, Yang, X, Zhang, B, Rao, Z, Liu, F. | 登録日 | 2022-12-12 | 公開日 | 2023-09-06 | 最終更新日 | 2023-10-18 | 実験手法 | ELECTRON MICROSCOPY (3.75 Å) | 主引用文献 | Structural insights into trehalose capture and translocation by mycobacterial LpqY-SugABC. Structure, 31, 2023
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6WOK
| Crystal structure of estrogen receptor alpha in complex with receptor degrader 6 | 分子名称: | (1R,3R)-1-(2,6-difluoro-4-{2-[3-(fluoromethyl)azetidin-1-yl]ethoxy}phenyl)-2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro-1H-beta-carboline, (2S)-3-(3-hydroxyphenyl)-2-(4-iodophenyl)-4-methyl-2H-1-benzopyran-6-ol, Estrogen receptor | 著者 | Kiefer, J.R, Vinogradova, M, Liang, J, Zhang, B, Wang, X, Labadie, S. | 登録日 | 2020-04-24 | 公開日 | 2020-07-01 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.309 Å) | 主引用文献 | Discovery of GNE-149 as a Full Antagonist and Efficient Degrader of Estrogen Receptor alpha for ER+ Breast Cancer. Acs Med.Chem.Lett., 11, 2020
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6XVH
| carbonic anhydrase with bound arylsulfonamide- boronic acid | 分子名称: | (4-sulfamoylphenyl)boronic acid, Carbonic anhydrase 2, ZINC ION | 著者 | Perez, C, Zhang, B. | 登録日 | 2020-01-22 | 公開日 | 2021-02-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | An easy to assemble, fully modulable, selectiv and
colorimetric artificial bio-sensor for fingerprintting
the recognition of neurotransmitters To Be Published
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6PET
| Crystal structure of 8-hydroxychromene compound 30 bound to estrogen receptor alpha | 分子名称: | (2S)-2-(4-{2-[3-(fluoromethyl)azetidin-1-yl]ethoxy}phenyl)-3-(3-hydroxyphenyl)-4-methyl-2H-1-benzopyran-8-ol, (2S)-3-(3-hydroxyphenyl)-2-(4-iodophenyl)-4-methyl-2H-1-benzopyran-6-ol, CHLORIDE ION, ... | 著者 | Kiefer, J.R, Vinogradova, M, Liang, J, Wang, X, Zbieg, J, Labadie, S.S, Zhang, B, Li, J, Liang, W. | 登録日 | 2019-06-20 | 公開日 | 2019-07-17 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.203 Å) | 主引用文献 | Discovery of a C-8 hydroxychromene as a potent degrader of estrogen receptor alpha with improved rat oral exposure over GDC-0927. Bioorg.Med.Chem.Lett., 29, 2019
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6PFM
| Crystal structure of GDC-0927 bound to estrogen receptor alpha | 分子名称: | (2S)-2-(4-{2-[3-(fluoromethyl)azetidin-1-yl]ethoxy}phenyl)-3-(3-hydroxyphenyl)-4-methyl-2H-1-benzopyran-6-ol, Estrogen receptor | 著者 | Kiefer, J.R, Vinogradova, M, Liang, J, Zhang, B, Wang, X, Zbieg, J.R, Labadie, S.S, Li, J, Ray, N.C, Ortwine, D. | 登録日 | 2019-06-21 | 公開日 | 2019-07-17 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | 主引用文献 | Discovery of a C-8 hydroxychromene as a potent degrader of estrogen receptor alpha with improved rat oral exposure over GDC-0927. Bioorg.Med.Chem.Lett., 29, 2019
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6IE4
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6IE5
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6IE7
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