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5EE5
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BU of 5ee5 by Molmil
Structure of human ARL1 in complex with the DCB domain of BIG1
分子名称: ACETATE ION, ADP-ribosylation factor-like protein 1, Brefeldin A-inhibited guanine nucleotide-exchange protein 1, ...
著者Galindo, A, Soler, N, Munro, S.
登録日2015-10-22
公開日2016-07-06
最終更新日2016-07-27
実験手法X-RAY DIFFRACTION (2.279 Å)
主引用文献Structural Insights into Arl1-Mediated Targeting of the Arf-GEF BIG1 to the trans-Golgi.
Cell Rep, 16, 2016
3SXM
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BU of 3sxm by Molmil
Metal-free FCD domain of TM0439 a putative transcriptional regulator
分子名称: BICARBONATE ION, Transcriptional regulator, GntR family
著者Czelakowski, G.P, Derewenda, Z.S, Integrated Center for Structure and Function Innovation (ISFI)
登録日2011-07-15
公開日2011-11-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Metal-free FCD domain of TM0439 a putative transcriptional regulator
To be Published
3SXY
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BU of 3sxy by Molmil
Metal-free full-length structure of Tm0439, a metal-binding FCD family transcriptional regulator
分子名称: Transcriptional regulator, GntR family
著者Czelakowski, G.P, Derewenda, Z.S, Integrated Center for Structure and Function Innovation (ISFI)
登録日2011-07-15
公開日2011-11-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.647 Å)
主引用文献Metal-free full-length structure of Tm0439, a metal-binding FCD family transcriptional regulator
To be Published
3SXZ
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BU of 3sxz by Molmil
Metal-free FCD domain of TM0439 a putative transcriptional regulator
分子名称: Transcriptional regulator, GntR family
著者Czelakowski, G.P, Derewenda, Z.S, Integrated Center for Structure and Function Innovation (ISFI)
登録日2011-07-15
公開日2011-11-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.322 Å)
主引用文献Metal-free FCD domain of TM0439 a putative transcriptional regulator
To be Published
3SXK
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BU of 3sxk by Molmil
Zn2+-bound FCD domain of TM0439, a putative transcriptional regulator
分子名称: BICARBONATE ION, SULFATE ION, Transcriptional regulator, ...
著者Czelakowski, G.P, Derewenda, Z.S, Integrated Center for Structure and Function Innovation (ISFI)
登録日2011-07-15
公開日2011-11-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Zn2+-bound FCD domain of TM0439, a putative transcriptional regulator
To be Published
4QOC
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BU of 4qoc by Molmil
crystal structure of compound 16 bound to MDM2(17-111), {(3R,5R,6S)-5-(3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-1-[(1S)-1-CYCLOPROPYL-2-(PYRROLIDIN-1-YLSULFONYL)ETHYL]-3-METHYL-2-OXOPIPERIDIN-3-YL}ACETIC ACID
分子名称: E3 ubiquitin-protein ligase Mdm2, {(3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-[(1S)-1-cyclopropyl-2-(pyrrolidin-1-ylsulfonyl)ethyl]-3-methyl-2-oxopiperidin-3-yl}acetic acid
著者Huang, X.
登録日2014-06-19
公開日2015-05-06
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Optimization beyond AMG 232: discovery and SAR of sulfonamides on a piperidinone scaffold as potent inhibitors of the MDM2-p53 protein-protein interaction.
Bioorg.Med.Chem.Lett., 24, 2014
8J22
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BU of 8j22 by Molmil
Cryo-EM structure of FFAR2 complex bound with TUG-1375
分子名称: (2R,4R)-2-(2-chlorophenyl)-3-[4-(3,5-dimethyl-1,2-oxazol-4-yl)phenyl]carbonyl-1,3-thiazolidine-4-carboxylic acid, Free fatty acid receptor 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Tai, L, Li, F, Sun, X, Tang, W, Wang, J.
登録日2023-04-14
公開日2024-01-24
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Molecular recognition and activation mechanism of short-chain fatty acid receptors FFAR2/3.
Cell Res., 34, 2024
8J21
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BU of 8j21 by Molmil
Cryo-EM structure of FFAR3 complex bound with butyrate acid
分子名称: Free fatty acid receptor 3, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Tai, L, Li, F, Sun, X, Tang, W, Wang, J.
登録日2023-04-14
公開日2024-01-24
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Molecular recognition and activation mechanism of short-chain fatty acid receptors FFAR2/3.
Cell Res., 34, 2024
8J20
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BU of 8j20 by Molmil
Cryo-EM structure of FFAR3 bound with valeric acid and AR420626
分子名称: (4R)-N-[2,5-bis(chloranyl)phenyl]-4-(furan-2-yl)-2-methyl-5-oxidanylidene-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide, Free fatty acid receptor 3, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Tai, L, Li, F, Sun, X, Tang, W, Wang, J.
登録日2023-04-14
公開日2024-01-24
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Molecular recognition and activation mechanism of short-chain fatty acid receptors FFAR2/3.
Cell Res., 34, 2024
8J24
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BU of 8j24 by Molmil
Cryo-EM structure of FFAR2 complex bound with acetic acid
分子名称: ACETATE ION, Free fatty acid receptor 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Tai, L, Li, F, Tang, W, Sun, X, Wang, J.
登録日2023-04-14
公開日2024-01-24
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Molecular recognition and activation mechanism of short-chain fatty acid receptors FFAR2/3.
Cell Res., 34, 2024
2A6P
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BU of 2a6p by Molmil
Structure Solution to 2.2 Angstrom and Functional Characterisation of the Open Reading Frame Rv3214 from Mycobacterium tuberculosis
分子名称: GLYCEROL, POSSIBLE PHOSPHOGLYCERATE MUTASE GPM2, SULFATE ION
著者Watkins, H.A, Yu, M, Baker, E.N, TB Structural Genomics Consortium (TBSGC)
登録日2005-07-03
公開日2006-05-16
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural and Functional Analysis of Rv3214 from Mycobacterium tuberculosis, a Protein with Conflicting Functional Annotations, Leads to Its Characterization as a Phosphatase.
J.Bacteriol., 188, 2006
1QDV
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BU of 1qdv by Molmil
N-TERMINAL DOMAIN, VOLTAGE-GATED POTASSIUM CHANNEL KV1.2 RESIDUES 33-131
分子名称: KV1.2 VOLTAGE-GATED POTASSIUM CHANNEL
著者Minor Jr, D.L, Lin, Y.-F, Mobley, B.C, Yu, M, Jan, Y.N, Jan, L.Y, Berger, J.M.
登録日1999-07-10
公開日2000-09-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The polar T1 interface is linked to conformational changes that open the voltage-gated potassium channel.
Cell(Cambridge,Mass.), 102, 2000
7FCV
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BU of 7fcv by Molmil
Cryo-EM structure of the Potassium channel AKT1 mutant from Arabidopsis thaliana
分子名称: PHOSPHATIDYLETHANOLAMINE, POTASSIUM ION, Potassium channel AKT1
著者Yang, G.H, Lu, Y.M, Jia, Y.T, Zhang, Y.M, Tang, R.F, Xu, X, Li, X.M, Lei, J.L.
登録日2021-07-15
公開日2022-11-09
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis for the activity regulation of a potassium channel AKT1 from Arabidopsis.
Nat Commun, 13, 2022
7XUF
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BU of 7xuf by Molmil
Cryo-EM structure of the AKT1-AtKC1 complex from Arabidopsis thaliana
分子名称: POTASSIUM ION, Potassium channel AKT1, Potassium channel KAT3
著者Yang, G.H, Lu, Y.M, Jia, Y.T, Yang, F, Zhang, Y.M, Xu, X, Li, X.M, Lei, J.L.
登録日2022-05-18
公開日2022-11-09
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis for the activity regulation of a potassium channel AKT1 from Arabidopsis.
Nat Commun, 13, 2022
7WSW
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BU of 7wsw by Molmil
Cryo-EM structure of the Potassium channel AKT1 from Arabidopsis thaliana
分子名称: PHOSPHATIDYLETHANOLAMINE, POTASSIUM ION, Potassium channel AKT1
著者Yang, G.H, Lu, Y.M, Zhang, Y.M, Jia, Y.T, Li, X.M, Lei, J.L.
登録日2022-02-02
公開日2022-11-09
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis for the activity regulation of a potassium channel AKT1 from Arabidopsis.
Nat Commun, 13, 2022
5ID2
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BU of 5id2 by Molmil
Asymmetry in the active site of Mycobacterium tuberculosis AhpE upon exposure to Mycothiol
分子名称: ACETATE ION, GLYCEROL, Putative peroxiredoxin Rv2238c
著者Kumar, A, Balakrishna, A.M, Gruber, G.
登録日2016-02-23
公開日2016-08-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献Redox chemistry of Mycobacterium tuberculosis alkylhydroperoxide reductase E (AhpE): Structural and mechanistic insight into a mycoredoxin-1 independent reductive pathway of AhpE via mycothiol
Free Radic. Biol. Med., 97, 2016
3UNO
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BU of 3uno by Molmil
Mycobacterium tuberculosis ferritin homolog, BfrB
分子名称: Probable bacterioferritin BfrB
著者McMath, L.M, Contreras, H, Goulding, C.W, TB Structural Genomics Consortium (TBSGC)
登録日2011-11-16
公開日2012-11-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.503 Å)
主引用文献Mycobacterium tuberculosis ferritin homolog, BfrB
To be Published
4P0M
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BU of 4p0m by Molmil
Crystal structure of an evolved putative penicillin-binding protein homolog, Rv2911, from Mycobacterium tuberculosis
分子名称: D-alanyl-D-alanine carboxypeptidase
著者Krieger, I, Yu, M, Bursey, E, Hung, L.-W, Terwilliger, T.C, TB Structural Genomics Consortium (TBSGC)
登録日2014-02-21
公開日2014-03-12
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Subfamily-Specific Adaptations in the Structures of Two Penicillin-Binding Proteins from Mycobacterium tuberculosis.
Plos One, 9, 2014

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件を2024-06-12に公開中

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