5WG8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wg8 by Molmil](/molmil-images/mine/5wg8) | Structure of PP5C with LB-100; 7-oxabicyclo[2.2.1]heptane-2,3-dicarbonyl moiety modeled in the density | 分子名称: | (1S,2R,3S,4R)-3-(4-methylpiperazine-1-carbonyl)-7-oxabicyclo[2.2.1]heptane-2-carboxylic acid, (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ... | 著者 | D'Arcy, B.M, Swingle, M.R, Honkanen, R.E, Prakash, A. | 登録日 | 2017-07-13 | 公開日 | 2018-07-18 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | The Antitumor Drug LB-100 Is a Catalytic Inhibitor of Protein Phosphatase 2A (PPP2CA) and 5 (PPP5C) Coordinating with the Active-Site Catalytic Metals in PPP5C. Mol. Cancer Ther., 18, 2019
|
|
1QBB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1qbb by Molmil](/molmil-images/mine/1qbb) | BACTERIAL CHITOBIASE COMPLEXED WITH CHITOBIOSE (DINAG) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHITOBIASE, SULFATE ION | 著者 | Tews, I, Perrakis, A, Oppenheim, A, Dauter, Z, Wilson, K.S, Vorgias, C.E. | 登録日 | 1996-06-07 | 公開日 | 1997-02-12 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Bacterial chitobiase structure provides insight into catalytic mechanism and the basis of Tay-Sachs disease. Nat.Struct.Biol., 3, 1996
|
|
5LQQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5lqq by Molmil](/molmil-images/mine/5lqq) | Structure of Autotaxin (ENPP2) with LM350 | 分子名称: | 3-(6-chloranyl-2-methyl-1-phenyl-indol-3-yl)sulfanylbenzoic acid, CALCIUM ION, Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, ... | 著者 | Keune, W.J, Heidebrecht, T, Castelmur, E, Joosten, R.P, Perrakis, A. | 登録日 | 2016-08-17 | 公開日 | 2016-12-28 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure-Activity Relationships of Small Molecule Autotaxin Inhibitors with a Discrete Binding Mode. J. Med. Chem., 60, 2017
|
|
1O9K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1o9k by Molmil](/molmil-images/mine/1o9k) | Crystal structure of the retinoblastoma tumour suppressor protein bound to E2F peptide | 分子名称: | RETINOBLASTOMA-ASSOCIATED PROTEIN, TRANSCRIPTION FACTOR E2F1 | 著者 | Xiao, B, Spencer, J, Clements, A, Ali-Khan, N, Mittnacht, S, Broceno, C, Burghammer, M, Perrakis, A, Marmorstein, R, Gamblin, S.J. | 登録日 | 2002-12-16 | 公開日 | 2003-03-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal Structure of the Retinoblastoma Tumor Suppressor Protein Bound to E2F and the Molecular Basis of its Regulation Proc.Natl.Acad.Sci.USA, 100, 2003
|
|
2XR9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2xr9 by Molmil](/molmil-images/mine/2xr9) | Crystal structure of Autotaxin (ENPP2) | 分子名称: | CALCIUM ION, ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE FAMILY MEMBER 2, IODIDE ION, ... | 著者 | Kamtekar, S, Hausmann, J, Day, J.E, Christodoulou, E, Perrakis, A. | 登録日 | 2010-09-13 | 公開日 | 2011-01-19 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structural basis of substrate discrimination and integrin binding by autotaxin. Nat. Struct. Mol. Biol., 18, 2011
|
|
1V6J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1v6j by Molmil](/molmil-images/mine/1v6j) | peanut lectin-lactose complex crystallized in orthorhombic form at acidic pH | 分子名称: | CALCIUM ION, Galactose-binding lectin, MANGANESE (II) ION, ... | 著者 | Kundhavai Natchiar, S, Arockia Jeyaprakash, A, Ramya, T.N.C, Thomas, C.J, Suguna, K, Surolia, A, Vijayan, M. | 登録日 | 2003-12-01 | 公開日 | 2004-02-10 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural plasticity of peanut lectin: an X-ray analysis involving variation in pH, ligand binding and crystal structure. Acta Crystallogr.,Sect.D, 60, 2004
|
|
1V6K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1v6k by Molmil](/molmil-images/mine/1v6k) | Peanut lectin-lactose complex in the presence of peptide(IWSSAGNVA) | 分子名称: | CALCIUM ION, Galactose-binding lectin, MANGANESE (II) ION, ... | 著者 | Kundhavai Natchiar, S, Arockia Jeyaprakash, A, Ramya, T.N.C, Thomas, C.J, Suguna, K, Surolia, A, Vijayan, M. | 登録日 | 2003-12-01 | 公開日 | 2004-02-10 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural plasticity of peanut lectin: an X-ray analysis involving variation in pH, ligand binding and crystal structure. Acta Crystallogr.,Sect.D, 60, 2004
|
|
1V6L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1v6l by Molmil](/molmil-images/mine/1v6l) | Peanut lectin-lactose complex in the presence of 9mer peptide (PVIWSSATG) | 分子名称: | CALCIUM ION, Galactose-binding lectin, MANGANESE (II) ION, ... | 著者 | Kundhavai Natchiar, S, Arockia Jeyaprakash, A, Ramya, T.N.C, Thomas, C.J, Suguna, K, Surolia, A, Vijayan, M. | 登録日 | 2003-12-01 | 公開日 | 2004-02-10 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural plasticity of peanut lectin: an X-ray analysis involving variation in pH, ligand binding and crystal structure. Acta Crystallogr.,Sect.D, 60, 2004
|
|
1RXF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1rxf by Molmil](/molmil-images/mine/1rxf) | DEACETOXYCEPHALOSPORIN C SYNTHASE COMPLEXED WITH FE(II) | 分子名称: | DEACETOXYCEPHALOSPORIN C SYNTHASE, FE (III) ION | 著者 | Valegard, K, Terwisscha Van Scheltinga, A.C, Lloyd, M.D, Hara, T, Ramaswamy, S, Perrakis, A, Thompson, A, Lee, H.J, Baldwin, J.E, Schofield, C.J, Hajdu, J, Andersson, I. | 登録日 | 1998-06-05 | 公開日 | 1999-06-08 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structure of a cephalosporin synthase. Nature, 394, 1998
|
|
1V6I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1v6i by Molmil](/molmil-images/mine/1v6i) | Peanut lectin-lactose complex in acidic pH | 分子名称: | CALCIUM ION, Galactose-binding lectin, MANGANESE (II) ION, ... | 著者 | Kundhavai Natchiar, S, Arockia Jeyaprakash, A, Ramya, T.N.C, Thomas, C.J, Suguna, K, Surolia, A, Vijayan, M. | 登録日 | 2003-12-01 | 公開日 | 2004-02-10 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structural plasticity of peanut lectin: an X-ray analysis involving variation in pH, ligand binding and crystal structure. Acta Crystallogr.,Sect.D, 60, 2004
|
|
1RXG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1rxg by Molmil](/molmil-images/mine/1rxg) | DEACETOXYCEPHALOSPORIN C SYNTHASE COMPLEXED WITH FE(II) AND 2-OXOGLUTARATE | 分子名称: | 2-OXOGLUTARIC ACID, DEACETOXYCEPHALOSPORIN C SYNTHASE, FE (III) ION, ... | 著者 | Valegard, K, Terwisscha Van Scheltinga, A.C, Lloyd, M.D, Hara, T, Ramaswamy, S, Perrakis, A, Thompson, A, Lee, H.J, Baldwin, J.E, Shofield, C.J, Hajdu, J, Andersson, I. | 登録日 | 1998-06-05 | 公開日 | 1999-06-08 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structure of a cephalosporin synthase. Nature, 394, 1998
|
|
3RMP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3rmp by Molmil](/molmil-images/mine/3rmp) | Structural basis for the recognition of attP substrates by P4-like integrases | 分子名称: | 5'-D(*TP*AP*AP*TP*GP*AP*CP*CP*AP*CP*CP*AP*AP*TP*A)-3', 5'-D(*TP*AP*TP*TP*GP*GP*TP*GP*GP*TP*CP*AP*TP*TP*A)-3', CP4-like integrase | 著者 | Szwagierczak, A, Popowicz, G.M, Holak, T.A, Rakin, A, Antonenka, U. | 登録日 | 2011-04-21 | 公開日 | 2012-04-25 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Structural basis for the recognition of attP substrates by P4-like integrases To be Published
|
|
8BBM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8bbm by Molmil](/molmil-images/mine/8bbm) | |
3G73
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3g73 by Molmil](/molmil-images/mine/3g73) | Structure of the FOXM1 DNA binding | 分子名称: | DNA (5'-D(P*AP*AP*AP*TP*TP*GP*TP*TP*TP*AP*TP*AP*AP*AP*CP*AP*GP*CP*CP*CP*G)-3'), DNA (5'-D(P*TP*TP*CP*GP*GP*GP*CP*TP*GP*TP*TP*TP*AP*TP*AP*AP*AP*CP*AP*AP*T)-3'), Forkhead box protein M1, ... | 著者 | Littler, D.R, Perrakis, A, Hibbert, R.G, Medema, R.H. | 登録日 | 2009-02-09 | 公開日 | 2009-03-03 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Structure of the FoxM1 DNA-recognition domain bound to a promoter sequence Nucleic Acids Res., 2010
|
|
2YLM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ylm by Molmil](/molmil-images/mine/2ylm) | |
4OAU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4oau by Molmil](/molmil-images/mine/4oau) | Complete human RNase L in complex with biological activators. | 分子名称: | 2-5A-dependent ribonuclease, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Han, Y, Donovan, J, Rath, S, Whitney, G, Chitrakar, A, Korennykh, A. | 登録日 | 2014-01-06 | 公開日 | 2014-03-12 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure of human RNase L reveals the basis for regulated RNA decay in the IFN response. Science, 343, 2014
|
|
5C9N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5c9n by Molmil](/molmil-images/mine/5c9n) | Crystal structure of GEMC1 coiled-coil domain | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Geminin coiled-coil domain-containing protein 1 | 著者 | Caillat, C, Perrakis, A. | 登録日 | 2015-06-28 | 公開日 | 2015-11-11 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The structure of the GemC1 coiled coil and its interaction with the Geminin family of coiled-coil proteins. Acta Crystallogr.,Sect.D, 71, 2015
|
|
1V6M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1v6m by Molmil](/molmil-images/mine/1v6m) | Peanut Lectin with 9mer peptide (IWSSAGNVA) | 分子名称: | CALCIUM ION, Galactose-binding lectin, MANGANESE (II) ION | 著者 | Kundhavai Natchiar, S, Arockia Jeyaprakash, A, Ramya, T.N.C, Thomas, C.J, Suguna, K, Surolia, A, Vijayan, M. | 登録日 | 2003-12-02 | 公開日 | 2004-02-10 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural plasticity of peanut lectin: an X-ray analysis involving variation in pH, ligand binding and crystal structure. Acta Crystallogr.,Sect.D, 60, 2004
|
|
1V6O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1v6o by Molmil](/molmil-images/mine/1v6o) | Peanut lectin complexed with 10mer peptide (PVRIWSSATG) | 分子名称: | CALCIUM ION, Galactose-binding lectin, MANGANESE (II) ION | 著者 | Kundhavai Natchiar, S, Arockia Jeyaprakash, A, Ramya, T.N.C, Thomas, C.J, Suguna, K, Surolia, A, Vijayan, M. | 登録日 | 2003-12-02 | 公開日 | 2004-02-10 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural plasticity of peanut lectin: an X-ray analysis involving variation in pH, ligand binding and crystal structure. Acta Crystallogr.,Sect.D, 60, 2004
|
|
1V6N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1v6n by Molmil](/molmil-images/mine/1v6n) | Peanut lectin with 9mer peptide (PVIWSSATG) | 分子名称: | CALCIUM ION, Galactose-binding lectin, MANGANESE (II) ION | 著者 | Kundhavai Natchiar, S, Arockia Jeyaprakash, A, Ramya, T.N.C, Thomas, C.J, Suguna, K, Surolia, A, Vijayan, M. | 登録日 | 2003-12-02 | 公開日 | 2004-02-10 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structural plasticity of peanut lectin: an X-ray analysis involving variation in pH, ligand binding and crystal structure. Acta Crystallogr.,Sect.D, 60, 2004
|
|
4OAV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4oav by Molmil](/molmil-images/mine/4oav) | Complete human RNase L in complex with 2-5A (5'-ppp heptamer), AMPPCP and RNA substrate. | 分子名称: | (2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-hydroxy-2-({[(S)-hydroxy{[(2R,3S,4S)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl]oxy}phosphoryl]oxy}methyl)tetrahydrofuran-3-yl dihydrogen phosphate, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | 著者 | Han, Y, Donovan, J, Rath, S, Whitney, G, Chitrakar, A, Korennykh, A. | 登録日 | 2014-01-06 | 公開日 | 2014-03-12 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure of human RNase L reveals the basis for regulated RNA decay in the IFN response. Science, 343, 2014
|
|
2KLT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2klt by Molmil](/molmil-images/mine/2klt) | Second Ca2+ binding domain of NCX1.3 | 分子名称: | Sodium/calcium exchanger 1 | 著者 | Hilge, M, Aelen, J, Foarce, A, Perrakis, A, Vuister, G.W. | 登録日 | 2009-07-08 | 公開日 | 2009-08-18 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Ca2+ regulation in the Na+/Ca2+ exchanger features a dual electrostatic switch mechanism. Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
2KLS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2kls by Molmil](/molmil-images/mine/2kls) | Apo-form of the second Ca2+ binding domain of NCX1.4 | 分子名称: | Sodium/calcium exchanger 1 | 著者 | Hilge, M, Aelen, J, Foarce, A, Perrakis, A, Vuister, G.W. | 登録日 | 2009-07-08 | 公開日 | 2009-08-18 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Ca2+ regulation in the Na+/Ca2+ exchanger features a dual electrostatic switch mechanism. Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
1EPU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1epu by Molmil](/molmil-images/mine/1epu) | X-RAY crystal structure of neuronal SEC1 from squid | 分子名称: | S-SEC1 | 著者 | Bracher, A, Perrakis, A, Dresbach, T, Betz, H, Weissenhorn, W. | 登録日 | 2000-03-29 | 公開日 | 2000-08-09 | 最終更新日 | 2017-10-04 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The X-ray crystal structure of neuronal Sec1 from squid sheds new light on the role of this protein in exocytosis. Structure Fold.Des., 8, 2000
|
|
5HJ0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5hj0 by Molmil](/molmil-images/mine/5hj0) | Crystal Structure of Mis18 'Yippee-like' Domain | 分子名称: | Kinetochore protein mis18, ZINC ION | 著者 | Medina-Pritchard, B, Subramanian, L, Allshire, R, Arockia Jeyaprakash, A. | 登録日 | 2016-01-12 | 公開日 | 2016-03-09 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | 主引用文献 | Centromere localization and function of Mis18 requires Yippee-like domain-mediated oligomerization. Embo Rep., 17, 2016
|
|