7K2W
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![BU of 7k2w by Molmil](/molmil-images/mine/7k2w) | Crystal structure of CTX-M-14 E166A/K234R Beta-lactamase in complex with hydrolyzed cefotaxime | 分子名称: | Beta-lactamase, CEFOTAXIME, C3' cleaved, ... | 著者 | Lu, S, Palzkill, T, Sankaran, B, Hu, L, Soeung, V, Prasad, B.V.V. | 登録日 | 2020-09-09 | 公開日 | 2020-11-04 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | A drug-resistant beta-lactamase variant changes the conformation of its active-site proton shuttle to alter substrate specificity and inhibitor potency. J.Biol.Chem., 295, 2020
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7LUP
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![BU of 7lup by Molmil](/molmil-images/mine/7lup) | Human TRiC/CCT complex with reovirus outer capsid protein sigma-3 | 分子名称: | Outer capsid protein sigma-3, T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, ... | 著者 | Knowlton, J.J, Gestaut, D, Ma, B, Taylor, G, Seven, A.B, Leitner, A, Wilson, G.J, Shanker, S, Yates, N.A, Prasad, B.V.V, Aebersold, R, Chiu, W, Frydman, J, Dermody, T.S. | 登録日 | 2021-02-22 | 公開日 | 2021-03-03 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (6.2 Å) | 主引用文献 | Structural and functional dissection of reovirus capsid folding and assembly by the prefoldin-TRiC/CCT chaperone network. Proc.Natl.Acad.Sci.USA, 118, 2021
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7LUM
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![BU of 7lum by Molmil](/molmil-images/mine/7lum) | Human TRiC in ATP/AlFx closed state | 分子名称: | T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, T-complex protein 1 subunit delta, ... | 著者 | Knowlton, J.J, Gestaut, D, Ma, B, Taylor, G, Seven, A.B, Leitner, A, Wilson, G.J, Shanker, S, Yates, N.A, Prasad, B.V.V, Aebersold, R, Chiu, W, Frydman, J, Dermody, T.S. | 登録日 | 2021-02-22 | 公開日 | 2021-03-03 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Structural and functional dissection of reovirus capsid folding and assembly by the prefoldin-TRiC/CCT chaperone network. Proc.Natl.Acad.Sci.USA, 118, 2021
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7K2X
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![BU of 7k2x by Molmil](/molmil-images/mine/7k2x) | Crystal structure of CTX-M-14 E166A/K234R Beta-lactamase | 分子名称: | Beta-lactamase, GLYCEROL | 著者 | Lu, S, Palzkill, T, Sankaran, B, Hu, L, Soeung, V, Prasad, B.V.V. | 登録日 | 2020-09-09 | 公開日 | 2020-11-04 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A drug-resistant beta-lactamase variant changes the conformation of its active-site proton shuttle to alter substrate specificity and inhibitor potency. J.Biol.Chem., 295, 2020
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7LK8
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![BU of 7lk8 by Molmil](/molmil-images/mine/7lk8) | Crystal structure of KPC-2 T215P mutant | 分子名称: | Beta-lactamase, SODIUM ION | 著者 | Furey, I, Palzkill, T, Sankaran, B, Hu, L, Prasad, B.V.V. | 登録日 | 2021-02-01 | 公開日 | 2021-05-26 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | Local interactions with the Glu166 base and the conformation of an active site loop play key roles in carbapenem hydrolysis by the KPC-2 beta-lactamase. J.Biol.Chem., 296, 2021
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7LLB
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![BU of 7llb by Molmil](/molmil-images/mine/7llb) | Crystal structure of KPC-2 S70G/T215P mutant with hydrolyzed meropenem | 分子名称: | (2S,3R)-2-[(2S,3R)-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfan yl-3-methyl-2,3-dihydro-1H-pyrrole-5-carboxylic acid, Carbapenem-hydrolyzing beta-lactamase KPC | 著者 | Furey, I, Palzkill, T, Sankaran, B, Hu, L, Prasad, B.V.V. | 登録日 | 2021-02-03 | 公開日 | 2021-05-26 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Local interactions with the Glu166 base and the conformation of an active site loop play key roles in carbapenem hydrolysis by the KPC-2 beta-lactamase. J.Biol.Chem., 296, 2021
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7LJK
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![BU of 7ljk by Molmil](/molmil-images/mine/7ljk) | Crystal structure of the deacylation deficient KPC-2 F72Y mutant | 分子名称: | Beta-lactamase | 著者 | Furey, I, Palzkill, T, Sankaran, B, Hu, L, Prasad, B.V.V. | 登録日 | 2021-01-29 | 公開日 | 2021-05-26 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Local interactions with the Glu166 base and the conformation of an active site loop play key roles in carbapenem hydrolysis by the KPC-2 beta-lactamase. J.Biol.Chem., 296, 2021
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7LNL
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![BU of 7lnl by Molmil](/molmil-images/mine/7lnl) | Crystal structure of KPC-2 S70G/T215P mutant with hydrolyzed imipenem | 分子名称: | (2R)-2-[(2S,3R)-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-(2-methanimidamidoethylsulfanyl)-2,3-dihydro-1H-pyrrole -5-carboxylic acid, Carbapenem-hydrolyzing beta-lactamase KPC | 著者 | Furey, I, Palzkill, T, Sankaran, B, Hu, L, Prasad, B.V.V. | 登録日 | 2021-02-07 | 公開日 | 2021-05-26 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Local interactions with the Glu166 base and the conformation of an active site loop play key roles in carbapenem hydrolysis by the KPC-2 beta-lactamase. J.Biol.Chem., 296, 2021
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7LLH
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![BU of 7llh by Molmil](/molmil-images/mine/7llh) | KPC-2 F72Y mutant with acylated imipenem | 分子名称: | (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid, Carbapenem-hydrolyzing beta-lactamase KPC | 著者 | Furey, I, Palzkill, T, Sankaran, B, Hu, L, Prasad, B.V.V. | 登録日 | 2021-02-03 | 公開日 | 2021-05-26 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Local interactions with the Glu166 base and the conformation of an active site loop play key roles in carbapenem hydrolysis by the KPC-2 beta-lactamase. J.Biol.Chem., 296, 2021
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4ZJD
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![BU of 4zjd by Molmil](/molmil-images/mine/4zjd) | |
4ZJA
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![BU of 4zja by Molmil](/molmil-images/mine/4zja) | |
4ZJ9
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![BU of 4zj9 by Molmil](/molmil-images/mine/4zj9) | |
7JIE
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![BU of 7jie by Molmil](/molmil-images/mine/7jie) | |
4S2M
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![BU of 4s2m by Molmil](/molmil-images/mine/4s2m) | Crystal Structure of OXA-163 complexed with iodide in the active site | 分子名称: | Beta-lactamase, IODIDE ION | 著者 | Stojanoski, V, Hu, L, Palzkill, T.G, Prasad, B. | 登録日 | 2015-01-21 | 公開日 | 2015-07-22 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.87 Å) | 主引用文献 | Structural Basis for Different Substrate Profiles of Two Closely Related Class D beta-Lactamases and Their Inhibition by Halogens. Biochemistry, 54, 2015
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4S2L
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![BU of 4s2l by Molmil](/molmil-images/mine/4s2l) | Crystal Structure of OXA-163 beta-lactamase | 分子名称: | Beta-lactamase, SODIUM ION | 著者 | Stojanoski, V, Liya, H, Palzkill, T.G, Prasad, B, Sankaran, B. | 登録日 | 2015-01-21 | 公開日 | 2015-07-22 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Structural Basis for Different Substrate Profiles of Two Closely Related Class D beta-Lactamases and Their Inhibition by Halogens. Biochemistry, 54, 2015
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2GH8
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![BU of 2gh8 by Molmil](/molmil-images/mine/2gh8) | X-ray structure of a native calicivirus | 分子名称: | Capsid protein | 著者 | Chen, R. | 登録日 | 2006-03-26 | 公開日 | 2006-05-16 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | X-ray structure of a native calicivirus: Structural insights into antigenic diversity and host specificity. Proc.Natl.Acad.Sci.Usa, 103, 2006
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1A6C
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![BU of 1a6c by Molmil](/molmil-images/mine/1a6c) | STRUCTURE OF TOBACCO RINGSPOT VIRUS | 分子名称: | TOBACCO RINGSPOT VIRUS CAPSID PROTEIN | 著者 | Johnson, J.E, Chandrasekar, V. | 登録日 | 1998-02-23 | 公開日 | 1998-07-15 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | The structure of tobacco ringspot virus: a link in the evolution of icosahedral capsids in the picornavirus superfamily. Structure, 6, 1998
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1QHD
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![BU of 1qhd by Molmil](/molmil-images/mine/1qhd) | CRYSTAL STRUCTURE OF VP6, THE MAJOR CAPSID PROTEIN OF GROUP A ROTAVIRUS | 分子名称: | CALCIUM ION, CHLORIDE ION, VIRAL CAPSID VP6, ... | 著者 | Mathieu, M, Petitpas, I, Rey, F.A. | 登録日 | 1999-04-29 | 公開日 | 2001-04-13 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Atomic structure of the major capsid protein of rotavirus: implications for the architecture of the virion. EMBO J., 20, 2001
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7KPT
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![BU of 7kpt by Molmil](/molmil-images/mine/7kpt) | Crystal structure of CtdE in complex with FAD and substrate 4 | 分子名称: | (6aR,7aS,11S,13aS)-6,6,11-trimethyl-4-(3-methylbut-2-en-1-yl)-6,6a,7,8,9,10,11,14-octahydro-5H,13H-13a,7a-(epiminomethano)quinolizino[2,3-b]carbazol-16-one, 1,2-ETHANEDIOL, CHLORIDE ION, ... | 著者 | Zhao, B, Hu, L. | 登録日 | 2020-11-12 | 公開日 | 2021-06-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | Structural basis of the stereoselective formation of the spirooxindole ring in the biosynthesis of citrinadins. Nat Commun, 12, 2021
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7KPQ
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![BU of 7kpq by Molmil](/molmil-images/mine/7kpq) | Crystal structure of CtdE in complex with FAD | 分子名称: | FAD-dependent monooxygenase CtdE, FLAVIN-ADENINE DINUCLEOTIDE | 著者 | Zhao, B, Hu, L. | 登録日 | 2020-11-12 | 公開日 | 2021-06-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis of the stereoselective formation of the spirooxindole ring in the biosynthesis of citrinadins. Nat Commun, 12, 2021
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4OPA
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4PM7
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![BU of 4pm7 by Molmil](/molmil-images/mine/4pm7) | Crystal structure of CTX-M-14 S70G:S237A in complex with cefotaxime at 1.29 Angstroms resolution | 分子名称: | (6R,7R)-3-(acetyloxymethyl)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyimino-ethanoyl]amino]-8-oxo-5-thia-1-azabicy clo[4.2.0]oct-2-ene-2-carboxylic acid, Beta-lactamase CTX-M-14 | 著者 | Adamski, C.J, Cardenas, A.M, Sankaran, B, Palzkill, T. | 登録日 | 2014-05-20 | 公開日 | 2014-12-31 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.29 Å) | 主引用文献 | Molecular Basis for the Catalytic Specificity of the CTX-M Extended-Spectrum beta-Lactamases. Biochemistry, 54, 2015
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4PM9
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![BU of 4pm9 by Molmil](/molmil-images/mine/4pm9) | Crystal structure of CTX-M-14 S70G:S237A:R276A beta-lactamase in complex with cefotaxime at 1.45 Angstroms resolution | 分子名称: | (6R,7R)-3-(acetyloxymethyl)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyimino-ethanoyl]amino]-8-oxo-5-thia-1-azabicy clo[4.2.0]oct-2-ene-2-carboxylic acid, Beta-lactamase CTX-M-14 | 著者 | Cardenas, A.M, Adamski, C.J, Sankaran, B, Brown, N.G, Horton, L.B, Palzkill, T. | 登録日 | 2014-05-20 | 公開日 | 2014-12-31 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.454 Å) | 主引用文献 | Molecular Basis for the Catalytic Specificity of the CTX-M Extended-Spectrum beta-Lactamases. Biochemistry, 54, 2015
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4PM8
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![BU of 4pm8 by Molmil](/molmil-images/mine/4pm8) | Crystal structure of CTX-M-14 S70G:S237A beta-lactamase at 1.17 Angstroms resolution | 分子名称: | Beta-lactamase CTX-M-14, SULFATE ION | 著者 | Adamski, C.J, Cardenas, A.M, Sankaran, B, Palzkill, T. | 登録日 | 2014-05-20 | 公開日 | 2014-12-31 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.169 Å) | 主引用文献 | Molecular Basis for the Catalytic Specificity of the CTX-M Extended-Spectrum beta-Lactamases. Biochemistry, 54, 2015
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4PMA
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![BU of 4pma by Molmil](/molmil-images/mine/4pma) | Crystal structure of CTX-M-14 S70G:S237A:R276A beta-lactamase at 1.39 Angstroms resolution | 分子名称: | Beta-lactamase CTX-M-14, SULFATE ION | 著者 | Cardenas, A.M, Adamski, C.J, Brown, N.G, Horton, L.B, Sankaran, B, Palzkill, T. | 登録日 | 2014-05-20 | 公開日 | 2014-12-31 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.399 Å) | 主引用文献 | Molecular Basis for the Catalytic Specificity of the CTX-M Extended-Spectrum beta-Lactamases. Biochemistry, 54, 2015
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