6RD2
 
 | | ENAH EVH1 in complex with Ac-[2-Cl-F]-[ProM-2]-[ProM-1]-TEDEL-NH2 | | 分子名称: | (3~{S},7~{R},10~{R},13~{S})-4-[(3~{S},6~{R},8~{a}~{S})-1'-[(2~{S})-2-acetamido-3-(2-chlorophenyl)propanoyl]-5-oxidanylidene-spiro[1,2,3,8~{a}-tetrahydroindolizine-6,2'-pyrrolidine]-3-yl]carbonyl-2-oxidanylidene-1,4-diazatricyclo[8.3.0.0^{3,7}]tridec-8-ene-13-carboxylic acid, GLYCEROL, NITRATE ION, ... | | 著者 | Barone, M, Roske, Y. | | 登録日 | 2019-04-12 | | 公開日 | 2020-05-13 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1 Å) | | 主引用文献 | Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6RCF
 | | ENAH EVH1 in complex with Ac-[2-Cl-F]-[ProM-2]-[ProM-15]-OH | | 分子名称: | 2-[(3~{a}~{R},6~{R},8~{a}~{S})-1-[(3~{S},6~{R},8~{a}~{S})-1'-[(2~{S})-2-acetamido-3-(2-chlorophenyl)propanoyl]-5-oxidanylidene-spiro[1,2,3,8~{a}-tetrahydroindolizine-6,2'-pyrrolidine]-3-yl]carbonyl-6-ethyl-8-oxidanylidene-3,3~{a},6,8~{a}-tetrahydro-2~{H}-pyrrolo[2,3-c]azepin-7-yl]ethanoic acid, NITRATE ION, Protein enabled homolog | | 著者 | Barone, M, Roske, Y. | | 登録日 | 2019-04-11 | | 公開日 | 2020-05-13 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6RCJ
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6I3R
 | | Structure, dynamics and roX2-lncRNA binding of tandem double-stranded RNA binding domains dsRBD1/2 of Drosophila helicase MLE | | 分子名称: | Dosage compensation regulator | | 著者 | Jagtap, P.K.A, Buelow, S.v, Masiewicz, P, Simon, B, Hennig, J. | | 登録日 | 2018-11-07 | | 公開日 | 2019-02-20 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure, dynamics and roX2-lncRNA binding of tandem double-stranded RNA binding domains dsRBD1,2 of Drosophila helicase Maleless.
Nucleic Acids Res., 47, 2019
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6SAW
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6SAX
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7Q33
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7ADZ
 | | Cryo-EM structure of an extracellular contractile injection system in marine bacterium Algoriphagus machipongonensis, the cap portion in extended state. | | 分子名称: | Phage tail protein, Putative phage tail sheath protein FI, cap adaptor protein (Algo2), ... | | 著者 | Xu, J, Ericson, C, Feldmueller, M, Lien, Y.W, Pilhofer, M. | | 登録日 | 2020-09-17 | | 公開日 | 2022-02-16 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Identification and structure of an extracellular contractile injection system from the marine bacterium Algoriphagus machipongonensis.
Nat Microbiol, 7, 2022
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7AEB
 | | Cryo-EM structure of an extracellular contractile injection system in marine bacterium Algoriphagus machipongonensis, the baseplate complex in extended state applied 6-fold symmetry. | | 分子名称: | Baseplate_J domain-containing protein, LysM domain-containing protein, Phage tail protein, ... | | 著者 | Xu, J, Ericson, C, Feldmueller, M, Lien, Y.W, Pilhofer, M. | | 登録日 | 2020-09-17 | | 公開日 | 2022-02-16 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Identification and structure of an extracellular contractile injection system from the marine bacterium Algoriphagus machipongonensis.
Nat Microbiol, 7, 2022
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7AE0
 | | Cryo-EM structure of an extracellular contractile injection system in marine bacterium Algoriphagus machipongonensis, the sheath-tube module in extended state. | | 分子名称: | Phage tail protein, Putative phage tail sheath protein FI | | 著者 | Xu, J, Ericson, C, Feldmueller, M, Lien, Y.W, Pilhofer, M. | | 登録日 | 2020-09-17 | | 公開日 | 2022-02-16 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | | 主引用文献 | Identification and structure of an extracellular contractile injection system from the marine bacterium Algoriphagus machipongonensis.
Nat Microbiol, 7, 2022
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7AEF
 | | Cryo-EM structure of an extracellular contractile injection system in marine bacterium Algoriphagus machipongonensis, the baseplate complex in extended state applied 3-fold symmetry. | | 分子名称: | Baseplate_J domain-containing protein, LysM domain-containing protein, Phage tail protein, ... | | 著者 | Xu, J, Ericson, C, Feldmueller, M, Lien, Y.W, Pilhofer, M. | | 登録日 | 2020-09-17 | | 公開日 | 2022-02-23 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Identification and structure of an extracellular contractile injection system from the marine bacterium Algoriphagus machipongonensis.
Nat Microbiol, 7, 2022
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7AEK
 | | Cryo-EM structure of an extracellular contractile injection system in marine bacterium Algoriphagus machipongonensis, the contracted sheath shell. | | 分子名称: | Putative phage tail sheath protein FI | | 著者 | Xu, J, Ericson, C, Feldmueller, M, Lien, Y.W, Pilhofer, M. | | 登録日 | 2020-09-17 | | 公開日 | 2022-02-16 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Identification and structure of an extracellular contractile injection system from the marine bacterium Algoriphagus machipongonensis.
Nat Microbiol, 7, 2022
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7B5H
 | | Cryo-EM structure of the contractile injection system base plate from Anabaena PCC7120 | | 分子名称: | All3314 protein, All3315 protein, All3316 protein, ... | | 著者 | Eisenstein, F, Weiss, G.L, Pilhofer, M. | | 登録日 | 2020-12-03 | | 公開日 | 2022-02-23 | | 最終更新日 | 2022-03-16 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structure of a thylakoid-anchored contractile injection system in multicellular cyanobacteria.
Nat Microbiol, 7, 2022
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7B5I
 | | Cryo-EM structure of the contractile injection system cap complex from Anabaena PCC7120 | | 分子名称: | All3324 protein, All3325 protein, All3326 protein, ... | | 著者 | Eisenstein, F, Weiss, G.L, Pilhofer, M. | | 登録日 | 2020-12-03 | | 公開日 | 2022-02-23 | | 最終更新日 | 2022-03-16 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structure of a thylakoid-anchored contractile injection system in multicellular cyanobacteria.
Nat Microbiol, 7, 2022
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7ZAP
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5O4E
 | | Crystal structure of VEGF in complex with heterodimeric Fcab JanusCT6 | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | | 著者 | Mlynek, G, Lobner, E, Kubinger, K, Humm, A, Obinger, C, Djinovic-Carugo, K. | | 登録日 | 2017-05-29 | | 公開日 | 2017-08-30 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Two-faced Fcab prevents polymerization with VEGF and reveals thermodynamics and the 2.15 angstrom crystal structure of the complex.
MAbs, 9, 2017
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