5WLU
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5WLV
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![BU of 5wlv by Molmil](/molmil-images/mine/5wlv) | Carbonic Anhydrase II in complex with aryloxy-2-hydroxypropylammine sulfonamide | 分子名称: | 4-{(2R)-2-hydroxy-3-[(propan-2-yl)amino]propoxy}-N-[2-(4-sulfamoylphenyl)ethyl]benzamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... | 著者 | Lomelino, C.L, Andring, J.T, McKenna, R. | 登録日 | 2017-07-27 | 公開日 | 2018-08-01 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Discovery of beta-Adrenergic Receptors Blocker-Carbonic Anhydrase Inhibitor Hybrids for Multitargeted Antiglaucoma Therapy. J. Med. Chem., 61, 2018
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5WLT
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![BU of 5wlt by Molmil](/molmil-images/mine/5wlt) | Carbonic Anhydrase IX-mimic in complex with aryloxy-2-hydroxypropylammine sulfonamide | 分子名称: | 4-{(2S)-2-hydroxy-3-[(propan-2-yl)amino]propoxy}benzene-1-sulfonamide, Carbonic anhydrase 2, GLYCEROL, ... | 著者 | Lomelino, C.L, Andring, J.T, McKenna, R. | 登録日 | 2017-07-27 | 公開日 | 2018-08-01 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | Discovery of beta-Adrenergic Receptors Blocker-Carbonic Anhydrase Inhibitor Hybrids for Multitargeted Antiglaucoma Therapy. J. Med. Chem., 61, 2018
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3D92
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![BU of 3d92 by Molmil](/molmil-images/mine/3d92) | Human carbonic anhydrase II bound with substrate carbon dioxide | 分子名称: | CARBON DIOXIDE, GLYCEROL, ZINC ION, ... | 著者 | Domsic, J.F, Avvaru, B.S, McKenna, R. | 登録日 | 2008-05-26 | 公開日 | 2008-09-02 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Entrapment of carbon dioxide in the active site of carbonic anhydrase II J.Biol.Chem., 283, 2008
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8EP2
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![BU of 8ep2 by Molmil](/molmil-images/mine/8ep2) | |
8EP9
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![BU of 8ep9 by Molmil](/molmil-images/mine/8ep9) | |
3D93
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![BU of 3d93 by Molmil](/molmil-images/mine/3d93) | |
8FQ4
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![BU of 8fq4 by Molmil](/molmil-images/mine/8fq4) | AAV1 VP3 Only Capsid | 分子名称: | Capsid protein | 著者 | Mietzsch, M, McKenna, R. | 登録日 | 2023-01-05 | 公開日 | 2023-02-08 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.27 Å) | 主引用文献 | Production and characterization of an AAV1-VP3-only capsid: An analytical benchmark standard. Mol Ther Methods Clin Dev, 29, 2023
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3RA8
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![BU of 3ra8 by Molmil](/molmil-images/mine/3ra8) | Structural studies of AAV8 capsid transitions associated with endosomal trafficking | 分子名称: | ADENOSINE MONOPHOSPHATE, Capsid protein | 著者 | Nam, H.-J, Gurda, B, McKenna, R, Porter, M, Byrne, B, Salganik, M, Muzyczka, N, Agbandje-McKenna, M. | 登録日 | 2011-03-27 | 公開日 | 2011-09-21 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural studies of adeno-associated virus serotype 8 capsid transitions associated with endosomal trafficking. J.Virol., 85, 2011
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8TEX
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![BU of 8tex by Molmil](/molmil-images/mine/8tex) | Avian Adeno-associated virus - empty capsid | 分子名称: | Capsid protein | 著者 | Hsi, J, Mietzsch, M, Chipman, P, Afione, S, Zeher, A, Huang, R, Chiorini, J, McKenna, R. | 登録日 | 2023-07-07 | 公開日 | 2023-08-30 | 最終更新日 | 2023-11-08 | 実験手法 | ELECTRON MICROSCOPY (2.54 Å) | 主引用文献 | Structural and antigenic characterization of the avian adeno-associated virus capsid. J.Virol., 97, 2023
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3RAA
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![BU of 3raa by Molmil](/molmil-images/mine/3raa) | Structural studies of AAV8 capsid transitions associated with endosomal trafficking | 分子名称: | ADENOSINE MONOPHOSPHATE, Capsid protein | 著者 | Nam, H.-J, Gurda, B, McKenna, R, Porter, M, Byrne, B, Salganik, M, Muzyczka, N, Agbandje-McKenna, M. | 登録日 | 2011-03-27 | 公開日 | 2011-09-21 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural studies of adeno-associated virus serotype 8 capsid transitions associated with endosomal trafficking. J.Virol., 85, 2011
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8TEY
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![BU of 8tey by Molmil](/molmil-images/mine/8tey) | Avian Adeno-associated virus - empty capsid | 分子名称: | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, Capsid protein | 著者 | Hsi, J, Mietzsch, M, Chipman, P, Afione, S, Zeher, A, Huang, R, Chiorini, J, McKenna, R. | 登録日 | 2023-07-07 | 公開日 | 2023-08-30 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | 主引用文献 | Structural and antigenic characterization of the avian adeno-associated virus capsid. J.Virol., 97, 2023
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3F9Q
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3RA4
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![BU of 3ra4 by Molmil](/molmil-images/mine/3ra4) | Structural studies of AAV8 capsid transitions associated with endosomal trafficking | 分子名称: | Capsid protein, DNA (5'-D(*CP*A)-3') | 著者 | Nam, H.-J, Gurda, B, McKenna, R, Porter, M, Byrne, B, Salganik, M, Muzyczka, N, Agbandje-McKenna, M. | 登録日 | 2011-03-27 | 公開日 | 2011-09-21 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural studies of adeno-associated virus serotype 8 capsid transitions associated with endosomal trafficking. J.Virol., 85, 2011
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3RA2
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![BU of 3ra2 by Molmil](/molmil-images/mine/3ra2) | Structural studies of AAV8 capsid transitions associated with endosomal trafficking | 分子名称: | Capsid protein | 著者 | Nam, H.-J, Gurda, B, McKenna, R, Porter, M, Byrne, B, Salganik, M, Muzyczka, N, Agbandje-McKenna, M. | 登録日 | 2011-03-26 | 公開日 | 2011-09-21 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural studies of adeno-associated virus serotype 8 capsid transitions associated with endosomal trafficking. J.Virol., 85, 2011
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3RA9
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![BU of 3ra9 by Molmil](/molmil-images/mine/3ra9) | Structural studies of AAV8 capsid transitions associated with endosomal trafficking | 分子名称: | Capsid protein, DNA (5'-D(P*CP*A)-3') | 著者 | Nam, H.-J, Gurda, B, McKenna, R, Porter, M, Byrne, B, Salganik, M, Muzyczka, N, Agbandje-McKenna, M. | 登録日 | 2011-03-27 | 公開日 | 2011-09-21 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural studies of adeno-associated virus serotype 8 capsid transitions associated with endosomal trafficking. J.Virol., 85, 2011
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1LZV
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![BU of 1lzv by Molmil](/molmil-images/mine/1lzv) | Site-Specific Mutant (Tyr7 replaced with His) of Human Carbonic Anhydrase II | 分子名称: | Carbonic Anhydrase II, ZINC ION | 著者 | Tu, C.K, Qian, M, An, H, Wadhwa, N.R, Duda, D.M, Yoshioka, C, Pathak, Y, McKenna, R, Laipis, P.J, Silverman, D.N. | 登録日 | 2002-06-11 | 公開日 | 2002-10-23 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Kinetic analysis of multiple proton shuttles in the active site of human carbonic anhydrase. J.Biol.Chem., 277, 2002
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3NG9
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![BU of 3ng9 by Molmil](/molmil-images/mine/3ng9) | Structure to Function Correlations for Adeno-associated Virus Serotype 1 | 分子名称: | 6-AMINOPYRIMIDIN-2(1H)-ONE, ADENINE, Capsid protein | 著者 | Govindasamy, L, Miller, E.B, Gurda, B, McKenna, R, Zolotukhin, S, Muzyczka, N, Agbandje-McKenna, M. | 登録日 | 2010-06-11 | 公開日 | 2011-12-21 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure to Function Correlations for Adeno-Associated Virus serotype 1 To be Published
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3NTT
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![BU of 3ntt by Molmil](/molmil-images/mine/3ntt) | Structural insights of Adeno-Associated virus 5. A gene therapy Vector for Cystic Fibrosis | 分子名称: | Capsid protein, GLYCEROL, SODIUM ION | 著者 | Govindasamy, L, DiMattia, M, Chiorini, J.A, McKenna, R, Muzyczka, N, Agbandje-McKenna, M. | 登録日 | 2010-07-05 | 公開日 | 2011-12-07 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.45 Å) | 主引用文献 | Structural insights into adeno-associated virus serotype 5. J.Virol., 87, 2013
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4DZ7
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4DZ9
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![BU of 4dz9 by Molmil](/molmil-images/mine/4dz9) | hCA II in complex with novel sulfonamide inhibitors Set D | 分子名称: | 4-[4-(cyclohexylmethyl)-1H-1,2,3-triazol-1-yl]-2,3,5,6-tetrafluorobenzenesulfonamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... | 著者 | Aggarwal, M, McKenna, R. | 登録日 | 2012-02-29 | 公開日 | 2013-03-27 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.491 Å) | 主引用文献 | hCA II in complex with novel sulfonamide inhibitors Set D To be Published
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4E5Q
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4ZWZ
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![BU of 4zwz by Molmil](/molmil-images/mine/4zwz) | Engineered Carbonic Anhydrase IX mimic in complex with a glucosyl sulfamate inhibitor | 分子名称: | Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ZINC ION, ... | 著者 | Mahon, B.P, Lomelino, C.L, Driscoll, J.M, McKenna, R. | 登録日 | 2015-05-19 | 公開日 | 2015-08-05 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | Mapping Selective Inhibition of the Cancer-Related Carbonic Anhydrase IX Using Structure-Activity Relationships of Glucosyl-Based Sulfamates. J.Med.Chem., 58, 2015
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7SV8
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7SV1
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![BU of 7sv1 by Molmil](/molmil-images/mine/7sv1) | |