7Y7E
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![BU of 7y7e by Molmil](/molmil-images/mine/7y7e) | Structure of the Bacterial Ribosome with human tRNA Asp(ManQ34) and mRNA(GAU) | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | 登録日 | 2022-06-22 | 公開日 | 2023-10-25 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (2.41 Å) | 主引用文献 | Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell, 186, 2023
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7Y7G
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![BU of 7y7g by Molmil](/molmil-images/mine/7y7g) | Structure of the Bacterial Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | 登録日 | 2022-06-22 | 公開日 | 2023-10-25 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (2.34 Å) | 主引用文献 | Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell, 186, 2023
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7Y7H
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![BU of 7y7h by Molmil](/molmil-images/mine/7y7h) | Structure of the Bacterial Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAC) | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | 登録日 | 2022-06-22 | 公開日 | 2023-10-25 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (2.51 Å) | 主引用文献 | Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell, 186, 2023
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5TNT
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![BU of 5tnt by Molmil](/molmil-images/mine/5tnt) | Discovery of novel aminobenzisoxazole derivatives as orally available factor IXa inhibitors | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Coagulation factor IX, N-[(1S,4S,7R)-2-(3-amino-4-chloro[1,2]oxazolo[5,4-c]pyridin-7-yl)-2-azabicyclo[2.2.1]heptan-7-yl]-2-chloro-4-(3-methyl-1H-1,2,4-triazol-1-yl)benzamide, ... | 著者 | Sakurada, I, Endo, T, Hikita, K, Hirabayashi, T, Hosaka, Y, Kato, Y, Maeda, Y, Matsumoto, S, Mizuno, T, Nagasue, A, Nishimura, T, Shimada, S, Shinozaki, M, Taguchi, K, Takeuchi, K, Yokoyama, T, Hruza, A, Reichert, P, Zhang, T, Wood, H.B, Nakao, K, Furusako, S. | 登録日 | 2016-10-14 | 公開日 | 2017-04-26 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Discovery of novel aminobenzisoxazole derivatives as orally available factor IXa inhibitors. Bioorg. Med. Chem. Lett., 27, 2017
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5TNO
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![BU of 5tno by Molmil](/molmil-images/mine/5tno) | Discovery of novel aminobenzisoxazole derivatives as orally available factor IXa inhibitors | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Coagulation factor IX, SODIUM ION, ... | 著者 | Sakurada, I, Endo, T, Hikita, K, Hirabayashi, T, Hosaka, Y, Kato, Y, Maeda, Y, Matsumoto, S, Mizuno, T, Nagasue, H, Nishimura, T, Shimada, S, Shinozaki, M, Taguchi, K, Takeuchi, K, Yokoyama, T, Hruza, A, Reichert, P, Zhang, T, Wood, H.B, Nakao, K, Furusako, S. | 登録日 | 2016-10-14 | 公開日 | 2017-04-26 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | Discovery of novel aminobenzisoxazole derivatives as orally available factor IXa inhibitors. Bioorg. Med. Chem. Lett., 27, 2017
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5ZSU
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![BU of 5zsu by Molmil](/molmil-images/mine/5zsu) | Structure of the human homo-hexameric LRRC8A channel at 4.25 Angstroms | 分子名称: | Volume-regulated anion channel subunit LRRC8A | 著者 | Kasuya, G, Nakane, T, Yokoyama, T, Shirouzu, M, Ishitani, R, Nureki, O. | 登録日 | 2018-04-29 | 公開日 | 2018-08-15 | 最終更新日 | 2018-09-26 | 実験手法 | ELECTRON MICROSCOPY (4.25 Å) | 主引用文献 | Cryo-EM structures of the human volume-regulated anion channel LRRC8. Nat. Struct. Mol. Biol., 25, 2018
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6JMR
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![BU of 6jmr by Molmil](/molmil-images/mine/6jmr) | CD98hc extracellular domain bound to HBJ127 Fab and MEM-108 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4F2 cell-surface antigen heavy chain, ... | 著者 | Lee, Y, Nishizawa, T, Kusakizako, T, Oda, K, Ishitani, R, Yokoyama, T, Nakane, T, Shirouzu, M, Nureki, O. | 登録日 | 2019-03-13 | 公開日 | 2019-06-19 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc. Nat.Struct.Mol.Biol., 26, 2019
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8JDK
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![BU of 8jdk by Molmil](/molmil-images/mine/8jdk) | Structure of the Human cytoplasmic Ribosome with human tRNA Asp(ManQ34) and mRNA(GAU) | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | 著者 | Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | 登録日 | 2023-05-14 | 公開日 | 2023-12-06 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (2.26 Å) | 主引用文献 | Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell, 186, 2023
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8JDM
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![BU of 8jdm by Molmil](/molmil-images/mine/8jdm) | Structure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (rotated state) | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | 著者 | Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | 登録日 | 2023-05-14 | 公開日 | 2023-12-06 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (2.67 Å) | 主引用文献 | Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell, 186, 2023
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8JDL
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![BU of 8jdl by Molmil](/molmil-images/mine/8jdl) | Structure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (non-rotated state) | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | 著者 | Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | 登録日 | 2023-05-14 | 公開日 | 2023-12-06 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (2.42 Å) | 主引用文献 | Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell, 186, 2023
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8JDJ
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![BU of 8jdj by Molmil](/molmil-images/mine/8jdj) | Structure of the Human cytoplasmic Ribosome with human tRNA Asp(Q34) and mRNA(GAU) | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | 著者 | Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | 登録日 | 2023-05-14 | 公開日 | 2023-12-06 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell, 186, 2023
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5HNZ
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![BU of 5hnz by Molmil](/molmil-images/mine/5hnz) | Structural basis of backwards motion in kinesin-14: plus-end directed nKn669 in the nucleotide-free state | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Shigematsu, H, Yokoyama, T, Kikkawa, M, Shirouzu, M, Nitta, R. | 登録日 | 2016-01-19 | 公開日 | 2016-08-10 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (5.8 Å) | 主引用文献 | Structural Basis of Backwards Motion in Kinesin-1-Kinesin-14 Chimera: Implication for Kinesin-14 Motility Structure, 24, 2016
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5HNX
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![BU of 5hnx by Molmil](/molmil-images/mine/5hnx) | Structural basis of backwards motion in kinesin-14: minus-end directed nKn664 in the nucleotide-free state | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Shigematsu, H, Yokoyama, T, Kikkawa, M, Shirouzu, M, Nitta, R. | 登録日 | 2016-01-19 | 公開日 | 2016-08-10 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (6.6 Å) | 主引用文献 | Structural Basis of Backwards Motion in Kinesin-1-Kinesin-14 Chimera: Implication for Kinesin-14 Motility Structure, 24, 2016
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5HNW
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![BU of 5hnw by Molmil](/molmil-images/mine/5hnw) | Structural basis of backwards motion in kinesin-14: minus-end directed nKn664 in the AMPPNP state | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Shigematsu, H, Yokoyama, T, Kikkawa, M, Shirouzu, M, Nitta, R. | 登録日 | 2016-01-19 | 公開日 | 2016-08-10 | 最終更新日 | 2018-07-25 | 実験手法 | ELECTRON MICROSCOPY (6.6 Å) | 主引用文献 | Structural Basis of Backwards Motion in Kinesin-1-Kinesin-14 Chimera: Implication for Kinesin-14 Motility Structure, 24, 2016
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5HNY
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![BU of 5hny by Molmil](/molmil-images/mine/5hny) | Structural basis of backwards motion in kinesin-14: plus-end directed nKn669 in the AMPPNP state | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Shigematsu, H, Yokoyama, T, Kikkawa, M, Shirouzu, M, Nitta, R. | 登録日 | 2016-01-19 | 公開日 | 2016-08-10 | 最終更新日 | 2016-11-02 | 実験手法 | ELECTRON MICROSCOPY (6.3 Å) | 主引用文献 | Structural Basis of Backwards Motion in Kinesin-1-Kinesin-14 Chimera: Implication for Kinesin-14 Motility Structure, 24, 2016
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8HU1
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![BU of 8hu1 by Molmil](/molmil-images/mine/8hu1) | E. coli 70S ribosome complexed with tRNA_Ile2 bearing L34 and ct6A37 in classical state | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Akiyama, N, Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | 登録日 | 2022-12-22 | 公開日 | 2024-04-03 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.69 Å) | 主引用文献 | Structural insights into the decoding capability of isoleucine tRNAs with lysidine and agmatidine. Nat.Struct.Mol.Biol., 31, 2024
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8HTZ
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![BU of 8htz by Molmil](/molmil-images/mine/8htz) | E. coli 70S ribosome complexed with H. marismortui tRNA_Ile2 bearing agm2C34 in classical state | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Akiyama, N, Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | 登録日 | 2022-12-22 | 公開日 | 2024-04-03 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Structural insights into the decoding capability of isoleucine tRNAs with lysidine and agmatidine. Nat.Struct.Mol.Biol., 31, 2024
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8HSP
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![BU of 8hsp by Molmil](/molmil-images/mine/8hsp) | E. coli 70S ribosome complexed with tRNA_Ile2 bearing L34 and t6A37 in classical state | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Akiyama, N, Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | 登録日 | 2022-12-20 | 公開日 | 2024-04-03 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.32 Å) | 主引用文献 | Structural insights into the decoding capability of isoleucine tRNAs with lysidine and agmatidine. Nat.Struct.Mol.Biol., 31, 2024
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8IFC
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![BU of 8ifc by Molmil](/molmil-images/mine/8ifc) | Arbekacin-bound E.coli 70S ribosome in the PURE system | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Tomono, J, Asano, K, Chiashi, T, Tanaka, Y, Yokoyama, T. | 登録日 | 2023-02-17 | 公開日 | 2024-02-14 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Direct visualization of ribosomes in the cell-free system revealed the functional evolution of aminoglycoside. J.Biochem., 175, 2024
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8IFE
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![BU of 8ife by Molmil](/molmil-images/mine/8ife) | Arbekacin-added human 80S ribosome | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | 著者 | Tomono, J, Asano, K, Chiashi, T, Tanaka, Y, Yokoyama, T. | 登録日 | 2023-02-17 | 公開日 | 2024-02-14 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.57 Å) | 主引用文献 | Direct visualization of ribosomes in the cell-free system revealed the functional evolution of aminoglycoside. J.Biochem., 175, 2024
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8IFD
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![BU of 8ifd by Molmil](/molmil-images/mine/8ifd) | Dibekacin-added human 80S ribosome | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | 著者 | Tomono, J, Asano, K, Chiashi, T, Tanaka, Y, Yokoyama, T. | 登録日 | 2023-02-17 | 公開日 | 2024-02-14 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.59 Å) | 主引用文献 | Direct visualization of ribosomes in the cell-free system revealed the functional evolution of aminoglycoside. J.Biochem., 175, 2024
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8IFB
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![BU of 8ifb by Molmil](/molmil-images/mine/8ifb) | Dibekacin-bound E.coli 70S ribosome in the PURE system | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Tomono, J, Asano, K, Chiashi, T, Tanaka, Y, Yokoyama, T. | 登録日 | 2023-02-17 | 公開日 | 2024-02-14 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.43 Å) | 主引用文献 | Direct visualization of ribosomes in the cell-free system revealed the functional evolution of aminoglycoside. J.Biochem., 175, 2024
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7W9Q
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![BU of 7w9q by Molmil](/molmil-images/mine/7w9q) | Crystal structure of V30M-TTR in complex with naringenin derivative-14 | 分子名称: | (2~{R})-2-(3-chloranyl-4-oxidanyl-phenyl)-5,7-bis(oxidanyl)-2,3-dihydrochromen-4-one, CALCIUM ION, Transthyretin | 著者 | Katayama, W, Shimane, A, Nabeshima, Y, Yokoyama, T, Mizuguchi, M. | 登録日 | 2021-12-10 | 公開日 | 2022-12-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.599 Å) | 主引用文献 | Chlorinated Naringenin Analogues as Potential Inhibitors of Transthyretin Amyloidogenesis. J.Med.Chem., 65, 2022
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7W9R
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![BU of 7w9r by Molmil](/molmil-images/mine/7w9r) | Crystal structure of V30M-TTR in complex with naringenin derivative-18 | 分子名称: | (2~{R})-2-[3,5-bis(chloranyl)-4-oxidanyl-phenyl]-5,7-bis(oxidanyl)-2,3-dihydrochromen-4-one, Transthyretin | 著者 | Katayama, W, Shimane, A, Nabeshima, Y, Yokoyama, T, Mizuguchi, M. | 登録日 | 2021-12-10 | 公開日 | 2022-12-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.997 Å) | 主引用文献 | Chlorinated Naringenin Analogues as Potential Inhibitors of Transthyretin Amyloidogenesis. J.Med.Chem., 65, 2022
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7EQE
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![BU of 7eqe by Molmil](/molmil-images/mine/7eqe) | Crystal Structure of a transcription factor | 分子名称: | TetR/AcrR family transcriptional regulator | 著者 | Uehara, S, Tsugita, A, Matsui, T, Yokoyama, T, Ostash, I, Ostash, B, Tanaka, Y. | 登録日 | 2021-05-01 | 公開日 | 2022-04-27 | 最終更新日 | 2022-10-19 | 実験手法 | X-RAY DIFFRACTION (2.399 Å) | 主引用文献 | The carbohydrate tail of landomycin A is responsible for its interaction with the repressor protein LanK. Febs J., 289, 2022
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