4YOX
 
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4YOV
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4YOY
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4YOW
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6K72
 | | eIF2(aP) - eIF2B complex | | 分子名称: | Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 2, Eukaryotic translation initiation factor 2 subunit 3, ... | | 著者 | Kashiwagi, K, Yokoyama, T, Ito, T. | | 登録日 | 2019-06-05 | | 公開日 | 2019-07-10 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | | 主引用文献 | Structural basis for eIF2B inhibition in integrated stress response.
Science, 364, 2019
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6K71
 | | eIF2 - eIF2B complex | | 分子名称: | Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 2, Eukaryotic translation initiation factor 2 subunit 3, ... | | 著者 | Kashiwagi, K, Yokoyama, T, Ito, T. | | 登録日 | 2019-06-05 | | 公開日 | 2019-07-10 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Structural basis for eIF2B inhibition in integrated stress response.
Science, 364, 2019
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6JLZ
 | | P-eIF2a - eIF2B complex | | 分子名称: | Eukaryotic translation initiation factor 2 subunit alpha, PHOSPHATE ION, Probable translation initiation factor eIF-2B subunit beta, ... | | 著者 | Kashiwagi, K, Ito, T. | | 登録日 | 2019-03-07 | | 公開日 | 2019-05-01 | | 最終更新日 | 2019-05-15 | | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | | 主引用文献 | Structural basis for eIF2B inhibition in integrated stress response.
Science, 364, 2019
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6JLY
 | | eIF2a - eIF2B complex | | 分子名称: | Eukaryotic translation initiation factor 2 subunit alpha, PHOSPHATE ION, Probable translation initiation factor eIF-2B subunit beta, ... | | 著者 | Kashiwagi, K, Ito, T. | | 登録日 | 2019-03-07 | | 公開日 | 2019-05-01 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structural basis for eIF2B inhibition in integrated stress response.
Science, 364, 2019
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3VRH
 | | Crystal structure of ph0300 | | 分子名称: | BICINE, Putative uncharacterized protein PH0300, ZINC ION | | 著者 | Nakagawa, H, Kuratani, M, Goto-Ito, S, Ito, T, Sekine, S.I, Yokoyama, S. | | 登録日 | 2012-04-10 | | 公開日 | 2013-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystallographic and mutational studies on the tRNA thiouridine synthetase TtuA.
Proteins, 2013
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2YX1
 | | Crystal structure of M.jannaschii tRNA m1G37 methyltransferase | | 分子名称: | Hypothetical protein MJ0883, SINEFUNGIN, ZINC ION | | 著者 | Goto-Ito, S, Ito, T, Ishii, R, Bessho, Y, Yokoyama, S. | | 登録日 | 2007-04-23 | | 公開日 | 2008-04-22 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of archaeal tRNA(m(1)G37)methyltransferase aTrm5.
Proteins, 72, 2008
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1Q1O
 | | Solution Structure of the PB1 Domain of Cdc24p (Long Form) | | 分子名称: | Cell division control protein 24 | | 著者 | Yoshinaga, S, Kohjima, M, Ogura, K, Yokochi, M, Takeya, R, Ito, T, Sumimoto, H, Inagaki, F. | | 登録日 | 2003-07-22 | | 公開日 | 2003-10-14 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The PB1 domain and the PC motif-containing region are structurally similar protein binding modules
EMBO J., 22, 2003
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3ECS
 | | Crystal structure of human eIF2B alpha | | 分子名称: | CHLORIDE ION, SULFATE ION, Translation initiation factor eIF-2B subunit alpha | | 著者 | Hiyama, T.B, Ito, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2008-09-01 | | 公開日 | 2009-09-01 | | 最終更新日 | 2014-02-05 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Crystal structure of the alpha subunit of human translation initiation factor 2B
J.Mol.Biol., 392, 2009
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2ZZN
 | | The complex structure of aTrm5 and tRNACys | | 分子名称: | MAGNESIUM ION, RNA (71-MER), S-ADENOSYLMETHIONINE, ... | | 著者 | Goto-Ito, S, Ito, T, Yokoyama, S. | | 登録日 | 2009-02-19 | | 公開日 | 2009-09-15 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Tertiary structure checkpoint at anticodon loop modification in tRNA functional maturation.
Nat.Struct.Mol.Biol., 16, 2009
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2YX0
 | | Crystal structure of P. horikoshii TYW1 | | 分子名称: | radical sam enzyme | | 著者 | Goto-Ito, S, Ishii, R, Ito, T, Shibata, R, Fusatomi, E, Sekine, S, Bessho, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-04-23 | | 公開日 | 2007-10-30 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Structure of an archaeal TYW1, the enzyme catalyzing the second step of wye-base biosynthesis
Acta Crystallogr.,Sect.D, 63, 2007
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2ZZM
 | | The complex structure of aTrm5 and tRNALeu | | 分子名称: | MAGNESIUM ION, RNA (84-MER), S-ADENOSYLMETHIONINE, ... | | 著者 | Goto-Ito, S, Ito, T, Yokoyama, S. | | 登録日 | 2009-02-19 | | 公開日 | 2009-09-15 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Tertiary structure checkpoint at anticodon loop modification in tRNA functional maturation
Nat.Struct.Mol.Biol., 16, 2009
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1TZ1
 | | Solution structure of the PB1 domain of CDC24P (short form) | | 分子名称: | Cell division control protein 24 | | 著者 | Yoshinaga, S, Terasawa, H, Ogura, K, Noda, Y, Ito, T, Sumimoto, H, Inagaki, F. | | 登録日 | 2004-07-09 | | 公開日 | 2005-09-06 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the PB1 domain of CDC24P (short form)
To be Published
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5B41
 | | Crystal structure of VDR-LBD complexed with 2-methylidene-19-nor-1a,25-dihydroxyvitamin D3 | | 分子名称: | (1R,3R)-5-(2-((1R,3aS,7aR,E)-1-((R)-6-hydroxy-6-methylheptan-2-yl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)-2- methylenecyclohexane-1,3-diol, Mediator of RNA polymerase II transcription subunit 1, Vitamin D3 receptor | | 著者 | Anami, Y, Itoh, T, Yamamoto, K. | | 登録日 | 2016-03-23 | | 公開日 | 2016-12-07 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Apo- and Antagonist-Binding Structures of Vitamin D Receptor Ligand-Binding Domain Revealed by Hybrid Approach Combining Small-Angle X-ray Scattering and Molecular Dynamics
J.Med.Chem., 59, 2016
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3AFR
 | | Crystal Structure of VDR-LBD/22S-Butyl-1a,24R-dihydroxyvitamin D3 complex | | 分子名称: | (1R,3S,5Z)-5-[(2E)-2-{(1R,3aS,7aR)-1-[(1R,2S,4R)-2-butyl-4-hydroxy-1,5-dimethylhexyl]-7a-methyloctahydro-4H-inden-4-yli dene}ethylidene]-4-methylidenecyclohexane-1,3-diol, 13-meric peptide from Mediator of RNA polymerase II transcription subunit 1, Vitamin D3 receptor | | 著者 | Inaba, Y, Nakabayashi, M, Itoh, T, Ikura, T, Ito, N, Yamamoto, K. | | 登録日 | 2010-03-10 | | 公開日 | 2010-03-31 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | 22S-Butyl-1alpha,24R-dihydroxyvitamin D(3): Recovery of vitamin D receptor agonistic activity
J.Steroid Biochem.Mol.Biol., 121, 2010
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1IPG
 | | SOLUTION STRUCTURE OF THE PB1 DOMAIN OF BEM1P | | 分子名称: | BEM1 PROTEIN | | 著者 | Terasawa, H, Noda, Y, Ito, T, Hatanaka, H, Ichikawa, S, Ogura, K, Sumimoto, H, Inagaki, F. | | 登録日 | 2001-05-14 | | 公開日 | 2001-08-15 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure and ligand recognition of the PB1 domain: a novel protein module binding to the PC motif.
EMBO J., 20, 2001
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1IP9
 | | SOLUTION STRUCTURE OF THE PB1 DOMAIN OF BEM1P | | 分子名称: | BEM1 PROTEIN | | 著者 | Terasawa, H, Noda, Y, Ito, T, Hatanaka, H, Ichikawa, S, Ogura, K, Sumimoto, H, Inagaki, F. | | 登録日 | 2001-04-26 | | 公開日 | 2001-08-15 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure and ligand recognition of the PB1 domain: a novel protein module binding to the PC motif.
EMBO J., 20, 2001
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7F67
 | | eIF2B-SFSV NSs-2-eIF2 | | 分子名称: | Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 3, Non-structural protein NS-S, ... | | 著者 | Kashiwagi, K, Ito, T. | | 登録日 | 2021-06-24 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.59 Å) | | 主引用文献 | eIF2B-capturing viral protein NSs suppresses the integrated stress response.
Nat Commun, 12, 2021
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7F66
 | | eIF2B-SFSV NSs-1-eIF2 | | 分子名称: | Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 3, Non-structural protein NS-S, ... | | 著者 | Kashiwagi, K, Ito, T. | | 登録日 | 2021-06-24 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | | 主引用文献 | eIF2B-capturing viral protein NSs suppresses the integrated stress response.
Nat Commun, 12, 2021
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7F64
 | | eIF2B-SFSV NSs | | 分子名称: | Non-structural protein NS-S, Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, ... | | 著者 | Kashiwagi, K, Ito, T. | | 登録日 | 2021-06-24 | | 公開日 | 2021-12-08 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (2.42 Å) | | 主引用文献 | eIF2B-capturing viral protein NSs suppresses the integrated stress response.
Nat Commun, 12, 2021
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3WTQ
 | | Crystal structure of VDR-LBD complexed with 22S-butyl-2-methylidene-19-nor-1a,25-dihydroxyvitamin D3 | | 分子名称: | (1R,3R,7E,17beta)-17-[(2R,3S)-3-butyl-6-hydroxy-6-methylheptan-2-yl]-2-methylidene-9,10-secoestra-5,7-diene-1,3-diol, Mediator of RNA polymerase II transcription subunit 1, Vitamin D3 receptor | | 著者 | Nakabayashi, M, Inaba, Y, Itoh, T, Anami, Y, Ikura, T, Ito, N, Yamamoto, K. | | 登録日 | 2014-04-15 | | 公開日 | 2015-04-15 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of VDR-LBD complexed with 22S-butyl-2-methylidene-19-nor-1a,25-dihydroxyvitamin D3
To be Published
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7F5S
 | | human delta-METTL18 60S ribosome | | 分子名称: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | | 著者 | Takahashi, M, Kashiwagi, K, Ito, T. | | 登録日 | 2021-06-22 | | 公開日 | 2022-06-22 | | 実験手法 | ELECTRON MICROSCOPY (2.72 Å) | | 主引用文献 | METTL18-mediated histidine methylation of RPL3 modulates translation elongation for proteostasis maintenance.
Elife, 11, 2022
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