5WKV
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5WKY
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5WKU
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5WKX
| Barium sites in the structure of a resting acid sensing ion channel | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1, ... | 著者 | Yoder, N, Gouaux, E. | 登録日 | 2017-07-25 | 公開日 | 2018-08-08 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (4.034 Å) | 主引用文献 | Divalent cation and chloride ion sites of chicken acid sensing ion channel 1a elucidated by x-ray crystallography. PLoS ONE, 13, 2018
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7LDD
| native AMPA receptor | 分子名称: | 11B8 scFv, 15F1 Fab heavy chain, 15F1 Fab light chain, ... | 著者 | Yu, J, Rao, P, Gouaux, E. | 登録日 | 2021-01-13 | 公開日 | 2021-05-12 | 最終更新日 | 2021-06-30 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Hippocampal AMPA receptor assemblies and mechanism of allosteric inhibition. Nature, 594, 2021
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6AWQ
| Anomalous chloride signal reveals the position of sertraline complexed with the serotonin transporter at the central site | 分子名称: | (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 8B6 antibody FAB heavy chain, ... | 著者 | Coleman, J.A, Gouaux, E. | 登録日 | 2017-09-06 | 公開日 | 2017-10-25 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (4.046 Å) | 主引用文献 | Structural basis for recognition of diverse antidepressants by the human serotonin transporter. Nat. Struct. Mol. Biol., 25, 2018
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6AVE
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6AWN
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6AWP
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6AWO
| X-ray structure of the ts3 human serotonin transporter complexed with sertraline at the central site | 分子名称: | (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 8B6 antibody FAB heavy chain, ... | 著者 | Coleman, J.A, Gouaux, E. | 登録日 | 2017-09-06 | 公開日 | 2017-10-25 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.534 Å) | 主引用文献 | Structural basis for recognition of diverse antidepressants by the human serotonin transporter. Nat. Struct. Mol. Biol., 25, 2018
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6CMC
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7LGW
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7LH3
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7LGU
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7LH2
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3USJ
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3USO
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3F3A
| Crystal Structure of LeuT bound to L-Tryptophan and Sodium | 分子名称: | SODIUM ION, TETRADECANE, TRYPTOPHAN, ... | 著者 | Singh, S.K, Piscitelli, C.L, Yamashita, A, Gouaux, E. | 登録日 | 2008-10-30 | 公開日 | 2008-12-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A competitive inhibitor traps LeuT in an open-to-out conformation. Science, 322, 2008
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3F3D
| Crystal structure of LeuT bound to L-Methionine and sodium | 分子名称: | METHIONINE, SODIUM ION, Transporter, ... | 著者 | Singh, S.K, Piscitelli, C.L, Yamashita, A, Gouaux, E. | 登録日 | 2008-10-30 | 公開日 | 2008-12-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | A competitive inhibitor traps LeuT in an open-to-out conformation. Science, 322, 2008
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3F3E
| Crystal structure of LeuT bound to L-leucine (30 mM) and sodium | 分子名称: | LEUCINE, SODIUM ION, Transporter, ... | 著者 | Singh, S.K, Piscitelli, C.L, Yamashita, A, Gouaux, E. | 登録日 | 2008-10-30 | 公開日 | 2008-12-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A competitive inhibitor traps LeuT in an open-to-out conformation. Science, 322, 2008
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3USI
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3USK
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3USL
| Crystal Structure of LeuT bound to L-selenomethionine in space group C2 from lipid bicelles | 分子名称: | ACETATE ION, IODIDE ION, PHOSPHOCHOLINE, ... | 著者 | Wang, H, Elferich, J, Gouaux, E. | 登録日 | 2011-11-23 | 公開日 | 2012-01-11 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context. Nat.Struct.Mol.Biol., 19, 2012
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3F3C
| Crystal structure of LeuT bound to 4-Fluoro-L-Phenylalanine and sodium | 分子名称: | 4-FLUORO-L-PHENYLALANINE, SODIUM ION, Transporter, ... | 著者 | Singh, S.K, Piscitelli, C.L, Yamashita, A, Gouaux, E. | 登録日 | 2008-10-30 | 公開日 | 2008-12-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A competitive inhibitor traps LeuT in an open-to-out conformation. Science, 322, 2008
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3USM
| Crystal Structure of LeuT bound to L-selenomethionine in space group C2 from lipid bicelles (collected at 1.2 A) | 分子名称: | IODIDE ION, PHOSPHOCHOLINE, SELENOMETHIONINE, ... | 著者 | Wang, H, Elferich, J, Gouaux, E. | 登録日 | 2011-11-23 | 公開日 | 2012-01-11 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (3.008 Å) | 主引用文献 | Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context. Nat.Struct.Mol.Biol., 19, 2012
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