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6FL9
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BU of 6fl9 by Molmil
The active form of a pentameric ion channel (sTeLIC) gated by alkaline pH - Wild type 2.3 Angstrom resolution
分子名称: Cys-loop ligand-gated ion channel, TETRAETHYLENE GLYCOL, nonyl beta-D-glucopyranoside
著者Hu, H, Delarue, M.
登録日2018-01-25
公開日2018-05-16
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of a pentameric ion channel gated by alkaline pH show a widely open pore and identify a cavity for modulation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4QH1
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BU of 4qh1 by Molmil
The GLIC pentameric Ligand-Gated Ion Channel (wild-type) in complex with bromoacetate
分子名称: BROMIDE ION, Proton-gated ion channel, SODIUM ION, ...
著者Fourati, Z, Delarue, M, Sauguet, L.
登録日2014-05-26
公開日2015-03-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural characterization of potential modulation sites in the extracellular domain of the prokaryotic pentameric proton-gated ion channel GLIC
Acta Crystallogr.,Sect.D, 2015
6FLI
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BU of 6fli by Molmil
The active form of a pentameric ion channel (sTeLIC) gated by alkaline pH - Co-crystallization with 4-bromo cinnamic acid
分子名称: 3-(4-bromophenyl)propanoic acid, Cys-loop ligand-gated ion channel, nonyl beta-D-glucopyranoside
著者Hu, H, Delarue, M.
登録日2018-01-26
公開日2018-05-16
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structures of a pentameric ion channel gated by alkaline pH show a widely open pore and identify a cavity for modulation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FVR
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BU of 6fvr by Molmil
The active form of a pentameric ion channel (sTeLIC) gated by alkaline pH - sTeLIC in complex with Cesium ions (Cs+)
分子名称: CESIUM ION, Cys-loop ligand-gated ion channel, nonyl beta-D-glucopyranoside
著者Hu, H, Delarue, M.
登録日2018-03-05
公開日2018-05-16
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献Crystal structures of a pentameric ion channel gated by alkaline pH show a widely open pore and identify a cavity for modulation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FVS
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BU of 6fvs by Molmil
The active form of a pentameric ion channel (sTeLIC) gated by alkaline pH - sTeLIC in complex with Barium ions (Ba2+)
分子名称: BARIUM ION, Cys-loop ligand-gated ion channel, ZINC ION, ...
著者Hu, H, Delarue, M.
登録日2018-03-05
公開日2018-05-16
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structures of a pentameric ion channel gated by alkaline pH show a widely open pore and identify a cavity for modulation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FVQ
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BU of 6fvq by Molmil
The active form of a pentameric ion channel (sTeLIC) gated by alkaline pH - R86A
分子名称: Cys-loop ligand-gated ion channel, TETRAETHYLENE GLYCOL, nonyl beta-D-glucopyranoside
著者Hu, H, Delarue, M.
登録日2018-03-05
公開日2018-05-16
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Crystal structures of a pentameric ion channel gated by alkaline pH show a widely open pore and identify a cavity for modulation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4QH5
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BU of 4qh5 by Molmil
The GLIC pentameric Ligand-Gated Ion Channel (wild-type) crystallized in phosphate buffer
分子名称: CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, DODECYL-BETA-D-MALTOSIDE, ...
著者Fourati, Z, Delarue, M, Sauguet, L.
登録日2014-05-26
公開日2015-03-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural characterization of potential modulation sites in the extracellular domain of the prokaryotic pentameric proton-gated ion channel GLIC
Acta Crystallogr.,Sect.D, 2015
4QZ9
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BU of 4qz9 by Molmil
Mouse Tdt in complex with a DSB substrate, C-A base pair
分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, 5'-D(*AP*AP*AP*AP*AP*C)-3', 5'-D(*TP*TP*TP*TP*TP*GP*A)-3', ...
著者Gouge, J, Delarue, M.
登録日2014-07-27
公開日2015-06-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural basis for a novel mechanism of DNA bridging and alignment in eukaryotic DSB DNA repair.
Embo J., 34, 2015
4QZE
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BU of 4qze by Molmil
Mouse Tdt, F401A mutant, in complex with a DSB substrate, C-G base pair
分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, 5'-D(*AP*AP*AP*AP*AP*C)-3', 5'-D(*TP*TP*TP*TP*TP*GP*GP*G)-3', ...
著者Gouge, J, Delarue, M.
登録日2014-07-27
公開日2015-06-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural basis for a novel mechanism of DNA bridging and alignment in eukaryotic DSB DNA repair.
Embo J., 34, 2015
4QZI
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BU of 4qzi by Molmil
Mouse Tdt, F401A mutant, in complex with a DSB substrate and Zn2+
分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, 5'-D(*AP*AP*AP*AP*AP*C)-3', 5'-D(*TP*TP*TP*TP*TP*GP*GP*G)-3', ...
著者Gouge, J, Delarue, M.
登録日2014-07-27
公開日2015-06-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structural basis for a novel mechanism of DNA bridging and alignment in eukaryotic DSB DNA repair.
Embo J., 34, 2015
4QZ8
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BU of 4qz8 by Molmil
Mouse Tdt in complex with a DSB substrate, C-G base pair
分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, 5'-D(*AP*AP*AP*AP*AP*C)-3', 5'-D(*TP*TP*TP*TP*TP*GP*G)-3', ...
著者Gouge, J, Delarue, M.
登録日2014-07-27
公開日2015-06-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for a novel mechanism of DNA bridging and alignment in eukaryotic DSB DNA repair.
Embo J., 34, 2015
4QZC
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BU of 4qzc by Molmil
Mouse Tdt, F405A mutant, in complex with a DSB substrate, C-G base pair
分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, 5'-D(*AP*AP*AP*AP*AP*C)-3', 5'-D(*TP*TP*TP*TP*TP*GP*G)-3', ...
著者Gouge, J, Delarue, M.
登録日2014-07-27
公開日2015-06-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural basis for a novel mechanism of DNA bridging and alignment in eukaryotic DSB DNA repair.
Embo J., 34, 2015
4QZG
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BU of 4qzg by Molmil
Mouse Tdt, F401A mutant, in complex with a DSB substrate, C-C base pair
分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, 5'-D(*AP*AP*AP*AP*AP*C)-3', 5'-D(*TP*TP*TP*TP*TP*GP*C)-3', ...
著者Gouge, J, Delarue, M.
登録日2014-07-27
公開日2015-06-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural basis for a novel mechanism of DNA bridging and alignment in eukaryotic DSB DNA repair.
Embo J., 34, 2015
6HJA
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BU of 6hja by Molmil
Xray structure of GLIC in complex with glutarate
分子名称: CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, DODECANE, ...
著者Fourati, Z, Delarue, M.
登録日2018-09-03
公開日2019-09-18
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural evidence for the binding of monocarboxylates and dicarboxylates at pharmacologically relevant extracellular sites of a pentameric ligand-gated ion channel.
Acta Crystallogr D Struct Biol, 76, 2020
4QZB
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BU of 4qzb by Molmil
Mouse Tdt in complex with a DSB substrate, C-T base pair
分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, 5'-D(*AP*AP*AP*AP*AP*C)-3', 5'-D(*TP*TP*TP*TP*TP*GP*T)-3', ...
著者Gouge, J, Delarue, M.
登録日2014-07-27
公開日2015-06-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural basis for a novel mechanism of DNA bridging and alignment in eukaryotic DSB DNA repair.
Embo J., 34, 2015
4QZF
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BU of 4qzf by Molmil
Mouse Tdt, F401A mutant, in complex with a DSB substrate, C-A base pair
分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, 5'-D(*AP*AP*AP*AP*AP*C)-3', 5'-D(*TP*TP*TP*TP*TP*GP*A)-3', ...
著者Gouge, J, Delarue, M.
登録日2014-07-27
公開日2015-06-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for a novel mechanism of DNA bridging and alignment in eukaryotic DSB DNA repair.
Embo J., 34, 2015
4QZA
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BU of 4qza by Molmil
Mouse Tdt in complex with a DSB substrate, C-C base pair
分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, 5'-D(*AP*AP*AP*AP*AP*C)-3', 5'-D(*TP*TP*TP*TP*TP*GP*C)-3', ...
著者Gouge, J, Delarue, M.
登録日2014-07-27
公開日2015-06-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural basis for a novel mechanism of DNA bridging and alignment in eukaryotic DSB DNA repair.
Embo J., 34, 2015
4QZD
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BU of 4qzd by Molmil
Mouse Tdt, F405A mutant, in complex with a DSB substrate, C-C base pair
分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, 5'-D(*AP*AP*AP*AP*AP*C)-3', 5'-D(*TP*TP*TP*TP*TP*GP*C)-3', ...
著者Gouge, J, Delarue, M.
登録日2014-07-27
公開日2015-06-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for a novel mechanism of DNA bridging and alignment in eukaryotic DSB DNA repair.
Embo J., 34, 2015
4QZH
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BU of 4qzh by Molmil
Mouse Tdt, F401A mutant, in complex with a DSB substrate, C-T base pair
分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, 5'-D(*AP*AP*AP*AP*AP*C)-3', 5'-D(*TP*TP*TP*TP*TP*GP*T)-3', ...
著者Gouge, J, Delarue, M.
登録日2014-07-27
公開日2015-06-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for a novel mechanism of DNA bridging and alignment in eukaryotic DSB DNA repair.
Embo J., 34, 2015
6HMF
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BU of 6hmf by Molmil
D-family DNA polymerase - DP1 subunit (3'-5' proof-reading exonuclease) H451 proof-reading deficient variant
分子名称: ACETATE ION, CACODYLATE ION, CALCIUM ION, ...
著者Raia, P, Delarue, M, Sauguet, L.
登録日2018-09-12
公開日2019-01-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of the DP1-DP2 PolD complex bound with DNA and its implications for the evolutionary history of DNA and RNA polymerases.
PLoS Biol., 17, 2019
4ILA
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BU of 4ila by Molmil
The pentameric ligand-gated ion channel GLIC A237F in complex with Cesium
分子名称: ACETATE ION, CESIUM ION, CHLORIDE ION, ...
著者Sauguet, L, Corringer, P.J, Delarue, M.
登録日2012-12-29
公開日2013-02-20
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels.
Embo J., 32, 2013
4IL4
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BU of 4il4 by Molmil
The pentameric ligand-gated ion channel GLIC in complex with Se-DDM
分子名称: ACETATE ION, CHLORIDE ION, Proton-gated ion channel, ...
著者Sauguet, L, Malherbe, L, Corringer, P.J, Delarue, M.
登録日2012-12-29
公開日2013-02-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels.
Embo J., 32, 2013
4IL9
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BU of 4il9 by Molmil
The pentameric ligand-gated ion channel GLIC A237F in complex with bromide
分子名称: ACETATE ION, BROMIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
著者Sauguet, L, Corringer, P.J, Delarue, M.
登録日2012-12-29
公開日2013-02-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.83 Å)
主引用文献Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels.
Embo J., 32, 2013
6HJ3
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BU of 6hj3 by Molmil
Xray structure of GLIC in complex with fumarate
分子名称: CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, DODECYL-BETA-D-MALTOSIDE, ...
著者Fourati, Z, Delarue, M.
登録日2018-08-31
公開日2019-09-11
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural evidence for the binding of monocarboxylates and dicarboxylates at pharmacologically relevant extracellular sites of a pentameric ligand-gated ion channel.
Acta Crystallogr D Struct Biol, 76, 2020
4ILB
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BU of 4ilb by Molmil
The pentameric ligand-gated ion channel GLIC A237F in complex with Rubidium
分子名称: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
著者Sauguet, L, Corringer, P.J, Delarue, M.
登録日2012-12-29
公開日2013-02-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels.
Embo J., 32, 2013

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