4QZH
Mouse Tdt, F401A mutant, in complex with a DSB substrate, C-T base pair
Summary for 4QZH
Entry DOI | 10.2210/pdb4qzh/pdb |
Related | 1JMS 4I27 4QZ8 4QZ9 4QZA 4QZB 4QZC 4QZD 4QZE 4QZF 4QZG 4QZI |
Descriptor | DNA nucleotidylexotransferase, 5'-D(*AP*AP*AP*AP*AP*C)-3', 5'-D(*TP*TP*TP*TP*TP*GP*T)-3', ... (7 entities in total) |
Functional Keywords | terminal deoxynucleotidyltransferase, nucleus, transferase-dna complex, transferase/dna |
Biological source | Mus musculus (mouse) More |
Cellular location | Isoform TDT-S: Nucleus. Isoform TDT-L: Cytoplasm. Nucleus : P09838 |
Total number of polymer chains | 4 |
Total formula weight | 51880.59 |
Authors | Gouge, J.,Delarue, M. (deposition date: 2014-07-27, release date: 2015-06-10, Last modification date: 2023-09-20) |
Primary citation | Gouge, J.,Rosario, S.,Romain, F.,Poitevin, F.,Beguin, P.,Delarue, M. Structural basis for a novel mechanism of DNA bridging and alignment in eukaryotic DSB DNA repair. Embo J., 34:1126-1142, 2015 Cited by PubMed: 25762590DOI: 10.15252/embj.201489643 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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