3NK7
| Structure of the Nosiheptide-resistance methyltransferase S-adenosyl-L-methionine Complex | 分子名称: | 23S rRNA methyltransferase, S-ADENOSYLMETHIONINE | 著者 | Yang, H, Wang, Z, Shen, Y, Wang, P, Murchie, A, Xu, Y. | 登録日 | 2010-06-18 | 公開日 | 2010-07-21 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal Structure of the Nosiheptide-Resistance Methyltransferase of Streptomyces actuosus Biochemistry, 49, 2010
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7RU1
| SARS-CoV-2-6P-Mut7 S protein (C3 symmetry) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Ozorowski, G, Turner, H.L, Ward, A.B. | 登録日 | 2021-08-16 | 公開日 | 2022-08-24 | 最終更新日 | 2024-01-17 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways. Iscience, 25, 2022
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7RU8
| CC6.30 fragment antigen binding in complex with SARS-CoV-2-6P-Mut7 S protein (RBD/Fv local refinement) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CC6.30 Fab Kappa chain Fv, ... | 著者 | Ozorowski, G, Turner, H.L, Ward, A.B. | 登録日 | 2021-08-16 | 公開日 | 2022-08-24 | 最終更新日 | 2022-09-14 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways. Iscience, 25, 2022
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7RU4
| CC6.33 IgG in complex with SARS-CoV-2-6P-Mut7 S protein (RBD/Fv local refinement) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CC6.33 IgG heavy chain Fv, ... | 著者 | Ozorowski, G, Turner, H.L, Ward, A.B. | 登録日 | 2021-08-16 | 公開日 | 2022-08-24 | 最終更新日 | 2022-09-14 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways. Iscience, 25, 2022
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7RU3
| CC6.33 IgG in complex with SARS-CoV-2-6P-Mut7 S protein (non-uniform refinement) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Ozorowski, G, Turner, H.L, Ward, A.B. | 登録日 | 2021-08-16 | 公開日 | 2022-08-24 | 最終更新日 | 2022-09-14 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways. Iscience, 25, 2022
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7RU2
| SARS-CoV-2-6P-Mut7 S protein (asymmetric) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Ozorowski, G, Turner, H.L, Ward, A.B. | 登録日 | 2021-08-16 | 公開日 | 2022-08-24 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways. Iscience, 25, 2022
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7RU5
| CC6.30 fragment antigen binding in complex with SARS-CoV-2-6P-Mut7 S protein (non-uniform refinement) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CC6.30 Fab heavy chain Fv, ... | 著者 | Ozorowski, G, Turner, H.L, Ward, A.B. | 登録日 | 2021-08-16 | 公開日 | 2022-08-24 | 最終更新日 | 2024-01-17 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways. Iscience, 25, 2022
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3IN4
| Bace1 with Compound 38 | 分子名称: | (5S)-2-amino-5-(2,6-diethylpyridin-4-yl)-3-methyl-5-(3-pyrimidin-5-ylphenyl)-3,5-dihydro-4H-imidazol-4-one, Beta-secretase 1 | 著者 | Olland, A.M. | 登録日 | 2009-08-11 | 公開日 | 2010-01-19 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Di-substituted pyridinyl aminohydantoins as potent and highly selective human beta-secretase (BACE1) inhibitors. Bioorg.Med.Chem., 18, 2010
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3IN3
| Bace1 with Compound 30 | 分子名称: | (5S)-2-amino-3-methyl-5-pyridin-4-yl-5-(3-pyridin-3-ylphenyl)-3,5-dihydro-4H-imidazol-4-one, Beta-secretase 1 | 著者 | Olland, A.M. | 登録日 | 2009-08-11 | 公開日 | 2010-01-19 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Di-substituted pyridinyl aminohydantoins as potent and highly selective human beta-secretase (BACE1) inhibitors. Bioorg.Med.Chem., 18, 2010
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3OOZ
| Bace1 in complex with the aminohydantoin Compound 102 | 分子名称: | (5R)-2-amino-5-[4-(difluoromethoxy)phenyl]-5-[4-fluoro-3-(5-fluoropent-1-yn-1-yl)phenyl]-3-methyl-3,5-dihydro-4H-imidazol-4-one, Beta-secretase 1 | 著者 | Olland, A.M. | 登録日 | 2010-08-31 | 公開日 | 2011-08-31 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Design and Synthesis of Aminohydantoins as Potent and Selective Human beta-Secretase (BACE1) Inhibitors with Enhanced Brain Permeability Bioorg.Med.Chem.Lett., 20, 2010
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4ANM
| Complex of CK2 with a CDC7 inhibitor | 分子名称: | 8-BROMANYL-2-[[(3S)-3-OXIDANYLPYRROLIDIN-1-YL]METHYL]-3H-[1]BENZOFURO[3,2-D]PYRIMIDIN-4-ONE, CASEIN KINASE II SUBUNIT ALPHA | 著者 | Stout, T.J. | 登録日 | 2012-03-20 | 公開日 | 2012-05-23 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Discovery of Xl413, a Potent and Selective Cdc7 Inhibitor. Bioorg.Med.Chem.Lett., 22, 2012
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4ALW
| Benzofuropyrimidinone Inhibitors of Pim-1 | 分子名称: | 8-BROMANYL-2-[(4-METHYLPIPERAZIN-1-YL)METHYL]-3H-[1]BENZOFURO[3,2-D]PYRIMIDIN-4-ONE, IMIDAZOLE, PIM-1 KINASE | 著者 | Stout, T.J, Adams, L. | 登録日 | 2012-03-05 | 公開日 | 2013-01-16 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | The Design, Synthesis, and Biological Evaluation of Pim Kinase Inhibitors. Bioorg.Med.Chem.Lett., 22, 2012
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4ALU
| Benzofuropyrimidinone Inhibitors of Pim-1 | 分子名称: | 8-bromo-2-(2-chlorophenyl)[1]benzofuro[3,2-d]pyrimidin-4(3H)-one, IMIDAZOLE, SERINE/THREONINE-PROTEIN KINASE PIM-1 | 著者 | Stout, T.J, Adams, L. | 登録日 | 2012-03-05 | 公開日 | 2013-01-16 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The Design, Synthesis, and Biological Evaluation of Pim Kinase Inhibitors. Bioorg.Med.Chem.Lett., 22, 2012
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4ALV
| Benzofuropyrimidinone Inhibitors of Pim-1 | 分子名称: | 8-bromo-2-{2-chloro-4-[(piperidin-4-ylmethyl)amino]phenyl}[1]benzofuro[3,2-d]pyrimidin-4(3H)-one, IMIDAZOLE, SERINE/THREONINE-PROTEIN KINASE PIM-1 | 著者 | Stout, T.J, Adams, L. | 登録日 | 2012-03-05 | 公開日 | 2013-01-16 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | The Design, Synthesis, and Biological Evaluation of Pim Kinase Inhibitors. Bioorg.Med.Chem.Lett., 22, 2012
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3S7L
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4IHG
| Chasing Acyl Carrier Protein Through a Catalytic Cycle of Lipid A Production | 分子名称: | 3-HYDROXY-TETRADECANOIC ACID, 4'-PHOSPHOPANTETHEINE, Acyl carrier protein, ... | 著者 | Masoudi, A, Raetz, C.R.H, Pemble, C.W. | 登録日 | 2012-12-18 | 公開日 | 2013-11-13 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | 主引用文献 | Chasing acyl carrier protein through a catalytic cycle of lipid A production. Nature, 505, 2014
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4IHF
| Chasing Acyl Carrier Protein Through a Catalytic Cycle of Lipid A Production | 分子名称: | Acyl carrier protein, CHLORIDE ION, S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] (3R)-3-hydroxytetradecanethioate, ... | 著者 | Masoudi, A, Raetz, C.R.H, Pemble, C.W. | 登録日 | 2012-12-18 | 公開日 | 2013-11-13 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Chasing acyl carrier protein through a catalytic cycle of lipid A production. Nature, 505, 2014
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3S7M
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4IHH
| Chasing Acyl Carrier Protein Through a Catalytic Cycle of Lipid A Production | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4'-PHOSPHOPANTETHEINE, Acyl carrier protein, ... | 著者 | Masoudi, A, Raetz, C.R.H, Pemble, C.W. | 登録日 | 2012-12-18 | 公開日 | 2013-11-13 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (2.132 Å) | 主引用文献 | Chasing acyl carrier protein through a catalytic cycle of lipid A production. Nature, 505, 2014
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7NAB
| Crystal structure of human neutralizing mAb CV3-25 binding to SARS-CoV-2 S MPER peptide 1140-1165 | 分子名称: | CITRIC ACID, CV3-25 Fab Heavy Chain, CV3-25 Fab Light Chain, ... | 著者 | Chen, Y, Tolbert, W.D, Pazgier, M. | 登録日 | 2021-06-21 | 公開日 | 2021-12-08 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structural basis and mode of action for two broadly neutralizing antibodies against SARS-CoV-2 emerging variants of concern. Cell Rep, 38, 2022
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8DTI
| Cryo-EM structure of Arabidopsis SPY in complex with GDP-fucose | 分子名称: | GUANOSINE-5'-DIPHOSPHATE-BETA-L-FUCOPYRANOSE, Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY | 著者 | Kumar, S, Zhou, Y, Dillard, L, Borgnia, M.J, Bartesaghi, A, Zhou, P. | 登録日 | 2022-07-25 | 公開日 | 2023-03-08 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Cryo-EM structure of the full length Arabidopsis SPY with complete TPRs Nat Commun, 2023
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8DTH
| Cryo-EM structure of Arabidopsis SPY alternative conformation 2 | 分子名称: | Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY | 著者 | Kumar, S, Zhou, Y, Dillard, L, Borgnia, M.J, Bartesaghi, A, Zhou, P. | 登録日 | 2022-07-25 | 公開日 | 2023-03-08 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Cryo-EM structure of the full length Arabidopsis SPY with complete TPRs Nat Commun, 2023
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8DTG
| Cryo-EM structure of Arabidopsis SPY alternative conformation 1 | 分子名称: | Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY | 著者 | Kumar, S, Zhou, Y, Dillard, L, Borgnia, M.J, Bartesaghi, A, Zhou, P. | 登録日 | 2022-07-25 | 公開日 | 2023-03-08 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Cryo-EM structure of the full length Arabidopsis SPY with complete TPRs Nat Commun, 2023
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8DTF
| Cryo-EM structure of the full length Arabidopsis SPY with complete TPRs | 分子名称: | Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY | 著者 | Kumar, S, Zhou, Y, Dillard, L, Borgnia, M.J, Bartesaghi, A, Zhou, P. | 登録日 | 2022-07-25 | 公開日 | 2023-03-08 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Cryo-EM structure of the full length Arabidopsis SPY with complete TPRs Nat Commun, 2023
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7U2E
| Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody ADI-55688 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ADI-55688 heavy chain, ADI-55688 light chain, ... | 著者 | Yuan, M, Zhu, X, Wilson, I.A. | 登録日 | 2022-02-23 | 公開日 | 2022-05-04 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | A broad and potent neutralization epitope in SARS-related coronaviruses. Proc.Natl.Acad.Sci.USA, 119, 2022
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