3KBL
 
 | | Crystal structure of the GLD-1 homodimerization domain from Caenorhabditis elegans N169A mutant at 2.28 A resolution | | 分子名称: | Female germline-specific tumor suppressor gld-1 | | 著者 | Beuck, C, Szymczyna, B.R, Kerkow, D.E, Carmel, A.B, Columbus, L, Stanfield, R.L, Williamson, J.R. | | 登録日 | 2009-10-20 | | 公開日 | 2010-03-09 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Structure of the GLD-1 homodimerization domain: insights into STAR protein-mediated translational regulation.
Structure, 18, 2010
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5C7M
 | | CRYSTAL STRUCTURE OF E3 LIGASE ITCH WITH A UB VARIANT | | 分子名称: | E3 ubiquitin-protein ligase Itchy homolog, Polyubiquitin-C | | 著者 | Walker, J.R, Hu, J, Dong, A, Wernimont, A, Zhang, W, Sidhu, S, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Tong, Y, Structural Genomics Consortium (SGC) | | 登録日 | 2015-06-24 | | 公開日 | 2016-03-16 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | | 主引用文献 | System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.
Mol.Cell, 62, 2016
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3KKA
 | | Co-crystal structure of the sam domains of EPHA1 AND EPHA2 | | 分子名称: | CHLORIDE ION, EPHRIN TYPE-A RECEPTOR 1, EPHRIN TYPE-A RECEPTOR 2 | | 著者 | Walker, J.R, Yermekbayeva, L, Butler-Cole, C, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2009-11-05 | | 公開日 | 2009-11-24 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Co-Crystal Structure of the SAM Domains of Human Ephrin Type-A Receptor 1 and Human Ephrin Type-A Receptor 2
To be Published
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3P1I
 | | Ligand binding domain of human ephrin type-B receptor 3 | | 分子名称: | CHLORIDE ION, Ephrin type-B receptor 3, SULFATE ION | | 著者 | Walker, J.R, Yermekbayeva, L, Seitova, A, Kania, J, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2010-09-30 | | 公開日 | 2011-01-19 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Ligand Binding Domain of Human Ephb3
To be Published
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3JYU
 | | Crystal structure of the N-terminal domains of the ubiquitin specific peptidase 4 (USP4) | | 分子名称: | 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, Ubiquitin carboxyl-terminal hydrolase | | 著者 | Bacik, J.P, Avvakumov, G, Walker, J.R, Xue, S, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2009-09-22 | | 公開日 | 2009-10-20 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | | 主引用文献 | Crystal structure of the N-terminal domains of the ubiquitin specific peptidase 4 (USP4)
To be Published
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3K0W
 | | Crystal structure of the tandem IG-like C2-type 2 domains of the human mucosa-associated lymphoid tissue lymphoma translocation protein 1 | | 分子名称: | CHLORIDE ION, Mucosa-associated lymphoid tissue lymphoma translocation protein 1, isoform 2 | | 著者 | Walker, J.R, Qiu, L, Butler-Cole, C, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2009-09-25 | | 公開日 | 2009-10-27 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of the Tandem Ig-Like C2-Type 2 Domains of the Human Mucosa-Associated Lymphoid Tissue Lymphoma Translocation Protein 1.
To be Published
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5C1M
 | | Crystal structure of active mu-opioid receptor bound to the agonist BU72 | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2R,3S,3aR,5aR,6R,11bR,11cS)-3a-methoxy-3,14-dimethyl-2-phenyl-2,3,3a,6,7,11c-hexahydro-1H-6,11b-(epiminoethano)-3,5a-methanonaphtho[2,1-g]indol-10-ol, CHOLESTEROL, ... | | 著者 | Huang, W.J, Manglik, A, Venkatakrishnan, A.J, Laeremans, T, Feinberg, E.N, Sanborn, A.L, Kato, H.E, Livingston, K.E, Thorsen, T.S, Kling, R, Granier, S, Gmeiner, P, Husbands, S.M, Traynor, J.R, Weis, W.I, Steyaert, J, Dror, R.O, Kobilka, B.K. | | 登録日 | 2015-06-15 | | 公開日 | 2015-08-05 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | Structural insights into mu-opioid receptor activation.
Nature, 524, 2015
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5CJ3
 | | Crystal structure of the zorbamycin binding protein (ZbmA) from Streptomyces flavoviridis with zorbamycin | | 分子名称: | CHLORIDE ION, COPPER (II) ION, Zbm binding protein, ... | | 著者 | Chang, C, Bigelow, L, Clancy, S, Babnigg, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Rudolf, J.D, Ma, M, Chang, C.-Y, Lohman, J.R, Yang, D, Shen, B, Enzyme Discovery for Natural Product Biosynthesis, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | 登録日 | 2015-07-13 | | 公開日 | 2015-07-22 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.6499 Å) | | 主引用文献 | Crystal Structure of the Zorbamycin-Binding Protein ZbmA, the Primary Self-Resistance Element in Streptomyces flavoviridis ATCC21892.
Biochemistry, 54, 2015
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5C7J
 | | CRYSTAL STRUCTURE OF NEDD4 WITH A UB VARIANT | | 分子名称: | E3 ubiquitin-protein ligase NEDD4, Polyubiquitin-C | | 著者 | Walker, J.R, Hu, J, Dong, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Tong, Y, Structural Genomics Consortium (SGC) | | 登録日 | 2015-06-24 | | 公開日 | 2016-03-16 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.
Mol.Cell, 62, 2016
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3OS5
 | | SET7/9-Dnmt1 K142me1 complex | | 分子名称: | 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, Dnmt1, ... | | 著者 | Esteve, P.-O, Chang, Y, Samaranayake, M, Upadhyay, A.K, Horton, J.R, Feehery, G.R, Cheng, X, Pradhan, S. | | 登録日 | 2010-09-08 | | 公開日 | 2010-12-15 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | A methylation and phosphorylation switch between an adjacent lysine and serine determines human DNMT1 stability.
Nat.Struct.Mol.Biol., 18, 2011
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3MKH
 | | Podospora anserina Nitroalkane Oxidase | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, NITROALKANE OXIDASE, ... | | 著者 | Tormos, J.R, Taylor, A.B, Daubner, S.C, Hart, P.J, Fitzpatrick, P.F. | | 登録日 | 2010-04-14 | | 公開日 | 2010-06-02 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.995 Å) | | 主引用文献 | Identification of a hypothetical protein from Podospora anserina as a nitroalkane oxidase.
Biochemistry, 49, 2010
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5CEH
 | | Structure of histone lysine demethylase KDM5A in complex with selective inhibitor | | 分子名称: | 7-oxo-5-phenyl-6-(propan-2-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile, Lysine-specific demethylase 5A, NICKEL (II) ION, ... | | 著者 | Kiefer, J.R, Vinogradova, M. | | 登録日 | 2015-07-06 | | 公開日 | 2016-05-18 | | 最終更新日 | 2017-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.14 Å) | | 主引用文献 | An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells.
Nat.Chem.Biol., 12, 2016
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3K6T
 | | Crystal structure of the GLD-1 homodimerization domain from Caenorhabditis elegans at 2.04 A resolution | | 分子名称: | Female germline-specific tumor suppressor gld-1 | | 著者 | Beuck, C, Szymczyna, B.R, Kerkow, D.E, Carmel, A.B, Columbus, L, Stanfield, R.L, Williamson, J.R. | | 登録日 | 2009-10-09 | | 公開日 | 2010-03-09 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Structure of the GLD-1 homodimerization domain: insights into STAR protein-mediated translational regulation.
Structure, 18, 2010
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5CEI
 | | Crystal structure of CDK8:Cyclin C complex with compound 22 | | 分子名称: | 1,2-ETHANEDIOL, 4-(4-iodophenoxy)-N-methylthieno[2,3-c]pyridine-2-carboxamide, Cyclin-C, ... | | 著者 | Kiefer, J.R, Schneider, E.V, Maskos, K, Koehler, M.F.T. | | 登録日 | 2015-07-06 | | 公開日 | 2016-02-10 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | Development of a Potent, Specific CDK8 Kinase Inhibitor Which Phenocopies CDK8/19 Knockout Cells.
Acs Med.Chem.Lett., 7, 2016
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5CHH
 | | Crystal structure of transcriptional regulator CdpR from Pseudomonas aeruginosa | | 分子名称: | AraC family transcriptional regulator | | 著者 | Zhao, J.R, Yu, X, Zhu, M, Kang, H.P, Kong, W.N, Ma, J.B, Deng, X, Gan, J.H, Liang, H.H. | | 登録日 | 2015-07-10 | | 公開日 | 2016-05-18 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural and Molecular Mechanism of CdpR Involved in Quorum-Sensing and Bacterial Virulence in Pseudomonas aeruginosa
Plos Biol., 14, 2016
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5CT9
 | | G158E/K44E/R57E/Y49E Bacillus subtilis lipase A with 5% [BMIM][Cl] | | 分子名称: | 1-butyl-3-methyl-1H-imidazol-3-ium, CHLORIDE ION, Esterase | | 著者 | Nordwald, E.M, Plaks, J.G, Snell, J.R, Sousa, M.C, Kaar, J.L. | | 登録日 | 2015-07-23 | | 公開日 | 2015-11-04 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Crystallographic Investigation of Imidazolium Ionic Liquid Effects on Enzyme Structure.
Chembiochem, 16, 2015
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3J3Q
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5CRI
 | | Wild-type Bacillus subtilis lipase A with 0% [BMIM][Cl] | | 分子名称: | Esterase, SULFATE ION | | 著者 | Nordwald, E.M, Plaks, J.G, Snell, J.R, Sousa, M.C, Kaar, J.L. | | 登録日 | 2015-07-22 | | 公開日 | 2015-11-04 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Crystallographic Investigation of Imidazolium Ionic Liquid Effects on Enzyme Structure.
Chembiochem, 16, 2015
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5CT6
 | | Wild-type Bacillus subtilis lipase A with 20% [BMIM][Cl] | | 分子名称: | 1-butyl-3-methyl-1H-imidazol-3-ium, CHLORIDE ION, Lipase EstA | | 著者 | Nordwald, E.M, Plaks, J.G, Snell, J.R, Sousa, M.C, Kaar, J.L. | | 登録日 | 2015-07-23 | | 公開日 | 2015-11-04 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.902 Å) | | 主引用文献 | Crystallographic Investigation of Imidazolium Ionic Liquid Effects on Enzyme Structure.
Chembiochem, 16, 2015
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5CT8
 | | G158E/K44E/R57E/Y49E Bacillus subtilis lipase A with 0% [BMIM][Cl] | | 分子名称: | Quadruple mutant lipase A, SULFATE ION | | 著者 | Nordwald, E.M, Plaks, J.G, Snell, J.R, Sousa, M.C, Kaar, J.L. | | 登録日 | 2015-07-23 | | 公開日 | 2015-11-04 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.29 Å) | | 主引用文献 | Crystallographic Investigation of Imidazolium Ionic Liquid Effects on Enzyme Structure.
Chembiochem, 16, 2015
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3P8D
 | | Crystal structure of the second Tudor domain of human PHF20 (homodimer form) | | 分子名称: | Medulloblastoma antigen MU-MB-50.72 | | 著者 | Cui, G, Lee, J, Thompson, J.R, Botuyan, M.V, Mer, G. | | 登録日 | 2010-10-13 | | 公開日 | 2011-06-22 | | 最終更新日 | 2012-09-26 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53.
Nat.Struct.Mol.Biol., 19, 2012
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5CT4
 | | Wild-type Bacillus subtilis lipase A with 5% [BMIM][Cl] | | 分子名称: | 1-butyl-3-methyl-1H-imidazol-3-ium, CHLORIDE ION, Esterase, ... | | 著者 | Nordwald, E.M, Plaks, J.G, Snell, J.R, Sousa, M.C, Kaar, J.L. | | 登録日 | 2015-07-23 | | 公開日 | 2015-11-04 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | | 主引用文献 | Crystallographic Investigation of Imidazolium Ionic Liquid Effects on Enzyme Structure.
Chembiochem, 16, 2015
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3MVD
 | | Crystal structure of the chromatin factor RCC1 in complex with the nucleosome core particle | | 分子名称: | DNA (146-MER), Histone H2A, Histone H2B 1.1, ... | | 著者 | Makde, R.D, England, J.R, Yennawar, H.P, Tan, S. | | 登録日 | 2010-05-04 | | 公開日 | 2010-08-25 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structure of RCC1 chromatin factor bound to the nucleosome core particle.
Nature, 467, 2010
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5CUR
 | | G158E/K44E/R57E/Y49E Bacillus subtilis lipase A with 20% [BMIM][Cl] | | 分子名称: | 1-butyl-3-methyl-1H-imidazol-3-ium, CHLORIDE ION, Esterase | | 著者 | Nordwald, E.M, Plaks, J.G, Snell, J.R, Sousa, M.C, Kaar, J.L. | | 登録日 | 2015-07-24 | | 公開日 | 2015-11-04 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.302 Å) | | 主引用文献 | Crystallographic Investigation of Imidazolium Ionic Liquid Effects on Enzyme Structure.
Chembiochem, 16, 2015
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5CXS
 | | Crystal Structure of Isoform 2 of Purine Nucleoside Phosphorylase complexed with MES | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Purine nucleoside phosphorylase | | 著者 | Torini, J.R, Romanello, L, Bird, L, Owens, R, Brandao-Neto, J, Pereira, H.M. | | 登録日 | 2015-07-29 | | 公開日 | 2016-08-03 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | The molecular structure of Schistosoma mansoni PNP isoform 2 provides insights into the nucleoside selectivity of PNPs.
PLoS ONE, 13, 2018
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