7DQ4
| Cryo-EM structure of CAR triggered Coxsackievirus B1 A-particle | 分子名称: | VP2, VP3, Virion protein 1 | 著者 | Li, S, Zhu, R, Xu, L, Cheng, T, Zheng, Q. | 登録日 | 2020-12-22 | 公開日 | 2021-05-05 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating. Cell Host Microbe, 29, 2021
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7DPZ
| Cryo-EM structure of Coxsackievirus B1 virion in complex with CAR | 分子名称: | Capsid protein VP4, Coxsackievirus and adenovirus receptor, VP2, ... | 著者 | Li, S, Zhu, R, Xu, L, Cheng, T, Zheng, Q. | 登録日 | 2020-12-22 | 公開日 | 2021-05-05 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating. Cell Host Microbe, 29, 2021
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7DQ1
| Cryo-EM structure of Coxsackievirus B1 virion in complex with CAR at physiological temperature | 分子名称: | Capsid protein VP4, Coxsackievirus and adenovirus receptor, VP2, ... | 著者 | Li, S, Zhu, R, Xu, L, Cheng, T, Zheng, Q. | 登録日 | 2020-12-22 | 公開日 | 2021-05-05 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating. Cell Host Microbe, 29, 2021
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7WOI
| Structure of the shaft pilin Spa2 from Corynebacterium glutamicum | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Spa2 | 著者 | Wu, Y.F, Wang, L.T, Huang, Y.Y, Zhong, C, Zhou, J. | 登録日 | 2022-01-21 | 公開日 | 2023-01-25 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | 主引用文献 | Accelerating the design of pili-enabled living materials using an integrative technological workflow. Nat.Chem.Biol., 2023
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7X31
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7XC3
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7XC4
| Crystal structure of SARS-CoV-2 NSP3 Macrodomain 3 (SARS-unique domain-M) in complex with Oxaprozin | 分子名称: | 3-(4,5-diphenyl-1,3-oxazol-2-yl)propanoic acid, Papain-like protease nsp3 | 著者 | Li, J, Liu, Y, Gao, J, Ruan, K. | 登録日 | 2022-03-22 | 公開日 | 2022-11-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Two Binding Sites of SARS-CoV-2 Macrodomain 3 Probed by Oxaprozin and Meclomen. J.Med.Chem., 65, 2022
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6UM7
| Cryo-EM structure of vaccine-elicited HIV-1 neutralizing antibody DH270.mu1 in complex with CH848 10.17DT Env | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DH270.mu1 Fab Heavy Chain, DH270.mu1 Fab Light chain, ... | 著者 | Acharya, P, Henderson, R.C, Saunders, K, Haynes, B.F. | 登録日 | 2019-10-09 | 公開日 | 2019-12-18 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Targeted selection of HIV-specific antibody mutations by engineering B cell maturation. Science, 366, 2019
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7L0E
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3T10
| HSP90 N-terminal domain bound to ACP | 分子名称: | Heat shock protein HSP 90-alpha, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | 著者 | Li, J. | 登録日 | 2011-07-21 | 公開日 | 2012-01-25 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | 主引用文献 | Structure insights into mechanisms of ATP hydrolysis and the activation of human heat-shock protein 90. Acta Biochim Biophys Sin (Shanghai), 44, 2012
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8HMH
| The closed state of RGLG2-VWA | 分子名称: | E3 ubiquitin-protein ligase RGLG2, MAGNESIUM ION | 著者 | Wang, Q. | 登録日 | 2022-12-03 | 公開日 | 2023-12-27 | 最終更新日 | 2024-01-03 | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | 主引用文献 | The regulation of RGLG2-VWA by Ca 2+ ions. Biochim Biophys Acta Proteins Proteom, 1872, 2024
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8I8Y
| A mutant of the C-terminal complex of proteins 4.1G and NuMA | 分子名称: | Engineered protein | 著者 | Hu, X. | 登録日 | 2023-02-06 | 公開日 | 2023-04-19 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Combined prediction and design reveals the target recognition mechanism of an intrinsically disordered protein interaction domain. Proc.Natl.Acad.Sci.USA, 120, 2023
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7WA9
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8IX3
| Cryo-EM structure of SARS-CoV-2 BA.4/5 spike protein in complex with 1G11 (local refinement) | 分子名称: | BA.4/5 variant spike protein, heavy chain of 1G11, light chain of 1G11 | 著者 | Sun, H, Jiang, Y, Zheng, Z, Zheng, Q, Li, S. | 登録日 | 2023-03-31 | 公開日 | 2023-11-15 | 最終更新日 | 2023-12-13 | 実験手法 | ELECTRON MICROSCOPY (3.98 Å) | 主引用文献 | Structural basis for broad neutralization of human antibody against Omicron sublineages and evasion by XBB variant. J.Virol., 97, 2023
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8JI0
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8JHZ
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7U87
| Product of 13mer primer with activated G monomer diastereomer 1 | 分子名称: | 5'-O-[(R)-(2-amino-1H-imidazol-1-yl)(sulfanyl)phosphoryl]guanosine, MAGNESIUM ION, RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*(G46)P*(G46))-3') | 著者 | Fang, Z, Szostak, J.W. | 登録日 | 2022-03-08 | 公開日 | 2023-03-15 | 最終更新日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (1.701 Å) | 主引用文献 | Catalytic Metal Ion-Substrate Coordination during Nonenzymatic RNA Primer Extension. J.Am.Chem.Soc., 2024
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7U88
| Product of 13mer primer with activated G monomer diastereomer 2 | 分子名称: | 5'-O-[(R)-(2-amino-1H-imidazol-1-yl)(sulfanyl)phosphoryl]guanosine, RNA (5'-R(*(LKC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*(G46)P*(G46))-3'), SULFATE ION | 著者 | Fang, Z, Szostak, J.W. | 登録日 | 2022-03-08 | 公開日 | 2023-03-15 | 最終更新日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Catalytic Metal Ion-Substrate Coordination during Nonenzymatic RNA Primer Extension. J.Am.Chem.Soc., 2024
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7U89
| Product of 14mer primer with activated G monomer diastereomer 1 | 分子名称: | 5'-O-[(R)-(2-amino-1H-imidazol-1-yl)(sulfanyl)phosphoryl]guanosine, RNA (5'-R(*(LKC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*GP*(G46))-3') | 著者 | Fang, Z, Szostak, J.W. | 登録日 | 2022-03-08 | 公開日 | 2023-03-15 | 最終更新日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Catalytic Metal Ion-Substrate Coordination during Nonenzymatic RNA Primer Extension. J.Am.Chem.Soc., 2024
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7U8A
| Product of 14mer primer with activated G monomer diastereomer 2 | 分子名称: | 5'-O-[(R)-(2-amino-1H-imidazol-1-yl)(sulfanyl)phosphoryl]guanosine, MAGNESIUM ION, RNA (5'-R(*(LKC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*GP*(G46))-3') | 著者 | Fang, Z, Szostak, J.W. | 登録日 | 2022-03-08 | 公開日 | 2023-03-15 | 最終更新日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Catalytic Metal Ion-Substrate Coordination during Nonenzymatic RNA Primer Extension. J.Am.Chem.Soc., 2024
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7UHE
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8I4V
| Cryo-EM structure of 5-subunit Smc5/6 arm region | 分子名称: | DNA repair protein KRE29, E3 SUMO-protein ligase MMS21, Structural maintenance of chromosomes protein 5, ... | 著者 | Qian, L, Jun, Z, Xiang, Z, Cheng, T, Zhaoning, W, Zhenguo, C, Wang, L. | 登録日 | 2023-01-21 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (5.97 Å) | 主引用文献 | Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms. Nat.Struct.Mol.Biol., 2024
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3TO4
| Structure of mouse Valpha14Vbeta2-mouseCD1d-alpha-Galactosylceramide | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... | 著者 | Patel, O, Rossjohn, J. | 登録日 | 2011-09-04 | 公開日 | 2011-12-14 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Vbeta2 natural killer T cell antigen receptor-mediated recognition of CD1d-glycolipid antigen. Proc.Natl.Acad.Sci.USA, 108, 2011
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7EOU
| Structure of the human GluN1/GluN2A NMDA receptor in the glycine/glutamate/GNE-6901/9-AA bound state | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 7-[(4-fluoranylphenoxy)methyl]-3-[(1~{R},2~{R})-2-(hydroxymethyl)cyclopropyl]-2-methyl-[1,3]thiazolo[3,2-a]pyrimidin-5-one, 9-AMINOACRIDINE, ... | 著者 | Wang, H, Zhu, S. | 登録日 | 2021-04-22 | 公開日 | 2021-06-30 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Gating mechanism and a modulatory niche of human GluN1-GluN2A NMDA receptors. Neuron, 109, 2021
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7EOQ
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