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7DQ4
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Cryo-EM structure of CAR triggered Coxsackievirus B1 A-particle
分子名称: VP2, VP3, Virion protein 1
著者Li, S, Zhu, R, Xu, L, Cheng, T, Zheng, Q.
登録日2020-12-22
公開日2021-05-05
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating.
Cell Host Microbe, 29, 2021
7DPZ
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BU of 7dpz by Molmil
Cryo-EM structure of Coxsackievirus B1 virion in complex with CAR
分子名称: Capsid protein VP4, Coxsackievirus and adenovirus receptor, VP2, ...
著者Li, S, Zhu, R, Xu, L, Cheng, T, Zheng, Q.
登録日2020-12-22
公開日2021-05-05
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating.
Cell Host Microbe, 29, 2021
7DQ1
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BU of 7dq1 by Molmil
Cryo-EM structure of Coxsackievirus B1 virion in complex with CAR at physiological temperature
分子名称: Capsid protein VP4, Coxsackievirus and adenovirus receptor, VP2, ...
著者Li, S, Zhu, R, Xu, L, Cheng, T, Zheng, Q.
登録日2020-12-22
公開日2021-05-05
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating.
Cell Host Microbe, 29, 2021
7WOI
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BU of 7woi by Molmil
Structure of the shaft pilin Spa2 from Corynebacterium glutamicum
分子名称: 1,2-ETHANEDIOL, GLYCEROL, Spa2
著者Wu, Y.F, Wang, L.T, Huang, Y.Y, Zhong, C, Zhou, J.
登録日2022-01-21
公開日2023-01-25
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献Accelerating the design of pili-enabled living materials using an integrative technological workflow.
Nat.Chem.Biol., 2023
7X31
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BU of 7x31 by Molmil
solution structure of an anti-CRISPR protein
分子名称: Anti-CRISPR protein (AcrIIC1)
著者Zhao, Y, Yang, F.
登録日2022-02-27
公開日2022-10-26
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献A redox switch regulates the assembly and anti-CRISPR activity of AcrIIC1.
Nat Commun, 13, 2022
7XC3
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BU of 7xc3 by Molmil
Crystal structure of SARS-CoV-2 NSP3 Macrodomain 3 (SARS-unique domain-M)
分子名称: Papain-like protease nsp3
著者Li, J, Gao, J.
登録日2022-03-22
公開日2022-11-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Two Binding Sites of SARS-CoV-2 Macrodomain 3 Probed by Oxaprozin and Meclomen.
J.Med.Chem., 65, 2022
7XC4
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Crystal structure of SARS-CoV-2 NSP3 Macrodomain 3 (SARS-unique domain-M) in complex with Oxaprozin
分子名称: 3-(4,5-diphenyl-1,3-oxazol-2-yl)propanoic acid, Papain-like protease nsp3
著者Li, J, Liu, Y, Gao, J, Ruan, K.
登録日2022-03-22
公開日2022-11-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Two Binding Sites of SARS-CoV-2 Macrodomain 3 Probed by Oxaprozin and Meclomen.
J.Med.Chem., 65, 2022
6UM7
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BU of 6um7 by Molmil
Cryo-EM structure of vaccine-elicited HIV-1 neutralizing antibody DH270.mu1 in complex with CH848 10.17DT Env
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, DH270.mu1 Fab Heavy Chain, DH270.mu1 Fab Light chain, ...
著者Acharya, P, Henderson, R.C, Saunders, K, Haynes, B.F.
登録日2019-10-09
公開日2019-12-18
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Targeted selection of HIV-specific antibody mutations by engineering B cell maturation.
Science, 366, 2019
7L0E
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BU of 7l0e by Molmil
Crystal structure of bovine RPE65 in complex with gem-difluoro emixustat and palmitate
分子名称: (1R)-3-amino-1-{3-[(4,4-difluorocyclohexyl)methoxy]phenyl}propan-1-ol, FE (II) ION, PALMITIC ACID, ...
著者Kiser, P.D.
登録日2020-12-11
公開日2021-06-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Rational Alteration of Pharmacokinetics of Chiral Fluorinated and Deuterated Derivatives of Emixustat for Retinal Therapy.
J.Med.Chem., 64, 2021
3T10
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BU of 3t10 by Molmil
HSP90 N-terminal domain bound to ACP
分子名称: Heat shock protein HSP 90-alpha, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
著者Li, J.
登録日2011-07-21
公開日2012-01-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.24 Å)
主引用文献Structure insights into mechanisms of ATP hydrolysis and the activation of human heat-shock protein 90.
Acta Biochim Biophys Sin (Shanghai), 44, 2012
8HMH
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BU of 8hmh by Molmil
The closed state of RGLG2-VWA
分子名称: E3 ubiquitin-protein ligase RGLG2, MAGNESIUM ION
著者Wang, Q.
登録日2022-12-03
公開日2023-12-27
最終更新日2024-01-03
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献The regulation of RGLG2-VWA by Ca 2+ ions.
Biochim Biophys Acta Proteins Proteom, 1872, 2024
8I8Y
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BU of 8i8y by Molmil
A mutant of the C-terminal complex of proteins 4.1G and NuMA
分子名称: Engineered protein
著者Hu, X.
登録日2023-02-06
公開日2023-04-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Combined prediction and design reveals the target recognition mechanism of an intrinsically disordered protein interaction domain.
Proc.Natl.Acad.Sci.USA, 120, 2023
7WA9
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BU of 7wa9 by Molmil
Crystal structure of MSMEG_5634 from Mycobacterium smegmatis
分子名称: MSMEG_5634
著者Wang, Z, Zhang, W.
登録日2021-12-12
公開日2022-10-19
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A Novel Acyl-AcpM-Binding Protein Confers Intrinsic Sensitivity to Fatty Acid Synthase Type II Inhibitors in Mycobacterium smegmatis
Front Microbiol, 13, 2022
8IX3
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BU of 8ix3 by Molmil
Cryo-EM structure of SARS-CoV-2 BA.4/5 spike protein in complex with 1G11 (local refinement)
分子名称: BA.4/5 variant spike protein, heavy chain of 1G11, light chain of 1G11
著者Sun, H, Jiang, Y, Zheng, Z, Zheng, Q, Li, S.
登録日2023-03-31
公開日2023-11-15
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.98 Å)
主引用文献Structural basis for broad neutralization of human antibody against Omicron sublineages and evasion by XBB variant.
J.Virol., 97, 2023
8JI0
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BU of 8ji0 by Molmil
Cryo-EM structure of the TcsH-CROP in complex with TMPRSS2
分子名称: Maltose/maltodextrin-binding periplasmic protein,Hemorrhagic toxin, Transmembrane protease serine 2
著者Zhou, R, Tao, L, Zhan, X.
登録日2023-05-25
公開日2024-03-20
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Molecular basis of TMPRSS2 recognition by Paeniclostridium sordellii hemorrhagic toxin.
Nat Commun, 15, 2024
8JHZ
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BU of 8jhz by Molmil
Cryo-EM structure of the TcsH-TMPRSS2 complex
分子名称: Hemorrhagic toxin, Transmembrane protease serine 2, ZINC ION
著者Zhou, R, Liang, T, Zhan, X.
登録日2023-05-25
公開日2024-03-20
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Molecular basis of TMPRSS2 recognition by Paeniclostridium sordellii hemorrhagic toxin.
Nat Commun, 15, 2024
7U87
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BU of 7u87 by Molmil
Product of 13mer primer with activated G monomer diastereomer 1
分子名称: 5'-O-[(R)-(2-amino-1H-imidazol-1-yl)(sulfanyl)phosphoryl]guanosine, MAGNESIUM ION, RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*(G46)P*(G46))-3')
著者Fang, Z, Szostak, J.W.
登録日2022-03-08
公開日2023-03-15
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (1.701 Å)
主引用文献Catalytic Metal Ion-Substrate Coordination during Nonenzymatic RNA Primer Extension.
J.Am.Chem.Soc., 2024
7U88
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BU of 7u88 by Molmil
Product of 13mer primer with activated G monomer diastereomer 2
分子名称: 5'-O-[(R)-(2-amino-1H-imidazol-1-yl)(sulfanyl)phosphoryl]guanosine, RNA (5'-R(*(LKC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*(G46)P*(G46))-3'), SULFATE ION
著者Fang, Z, Szostak, J.W.
登録日2022-03-08
公開日2023-03-15
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Catalytic Metal Ion-Substrate Coordination during Nonenzymatic RNA Primer Extension.
J.Am.Chem.Soc., 2024
7U89
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BU of 7u89 by Molmil
Product of 14mer primer with activated G monomer diastereomer 1
分子名称: 5'-O-[(R)-(2-amino-1H-imidazol-1-yl)(sulfanyl)phosphoryl]guanosine, RNA (5'-R(*(LKC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*GP*(G46))-3')
著者Fang, Z, Szostak, J.W.
登録日2022-03-08
公開日2023-03-15
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Catalytic Metal Ion-Substrate Coordination during Nonenzymatic RNA Primer Extension.
J.Am.Chem.Soc., 2024
7U8A
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BU of 7u8a by Molmil
Product of 14mer primer with activated G monomer diastereomer 2
分子名称: 5'-O-[(R)-(2-amino-1H-imidazol-1-yl)(sulfanyl)phosphoryl]guanosine, MAGNESIUM ION, RNA (5'-R(*(LKC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*GP*(G46))-3')
著者Fang, Z, Szostak, J.W.
登録日2022-03-08
公開日2023-03-15
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Catalytic Metal Ion-Substrate Coordination during Nonenzymatic RNA Primer Extension.
J.Am.Chem.Soc., 2024
7UHE
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BU of 7uhe by Molmil
Taf14 ET domain in complex with C-terminal tail of Taf2
分子名称: C-terminal tail of Transcription initiation factor TFIID subunit 2, Transcription initiation factor TFIID subunit 14
著者Klein, B.J, Kutateladze, T.G.
登録日2022-03-26
公開日2022-08-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Taf2 mediates DNA binding of Taf14.
Nat Commun, 13, 2022
8I4V
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BU of 8i4v by Molmil
Cryo-EM structure of 5-subunit Smc5/6 arm region
分子名称: DNA repair protein KRE29, E3 SUMO-protein ligase MMS21, Structural maintenance of chromosomes protein 5, ...
著者Qian, L, Jun, Z, Xiang, Z, Cheng, T, Zhaoning, W, Zhenguo, C, Wang, L.
登録日2023-01-21
公開日2024-06-26
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (5.97 Å)
主引用文献Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms.
Nat.Struct.Mol.Biol., 2024
3TO4
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BU of 3to4 by Molmil
Structure of mouse Valpha14Vbeta2-mouseCD1d-alpha-Galactosylceramide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ...
著者Patel, O, Rossjohn, J.
登録日2011-09-04
公開日2011-12-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Vbeta2 natural killer T cell antigen receptor-mediated recognition of CD1d-glycolipid antigen.
Proc.Natl.Acad.Sci.USA, 108, 2011
7EOU
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BU of 7eou by Molmil
Structure of the human GluN1/GluN2A NMDA receptor in the glycine/glutamate/GNE-6901/9-AA bound state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 7-[(4-fluoranylphenoxy)methyl]-3-[(1~{R},2~{R})-2-(hydroxymethyl)cyclopropyl]-2-methyl-[1,3]thiazolo[3,2-a]pyrimidin-5-one, 9-AMINOACRIDINE, ...
著者Wang, H, Zhu, S.
登録日2021-04-22
公開日2021-06-30
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Gating mechanism and a modulatory niche of human GluN1-GluN2A NMDA receptors.
Neuron, 109, 2021
7EOQ
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Structure of the human GluN1/GluN2A NMDA receptor in the glycine/CPP bound state
分子名称: (2R)-4-(3-phosphonopropyl)piperazine-2-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ...
著者Wang, H, Zhu, S.
登録日2021-04-22
公開日2021-06-30
最終更新日2021-08-18
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Gating mechanism and a modulatory niche of human GluN1-GluN2A NMDA receptors.
Neuron, 109, 2021

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