5K08
| RecA mini intein-Zeise's salt complex | 分子名称: | 3,3',3''-phosphanetriyltripropanoic acid, RecA mini intein, SULFATE ION, ... | 著者 | Li, Z, Li, H.M. | 登録日 | 2016-05-17 | 公開日 | 2016-09-21 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.401 Å) | 主引用文献 | Structural insights into protein splicing inhibition by platinum therapeutics as potential anti-microbials To be published
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4AGW
| Discovery of a small molecule type II inhibitor of wild-type and gatekeeper mutants of BCR-ABL, PDGFRalpha, Kit, and Src kinases | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-{2-[(cyclopropylcarbonyl)amino][1,3]thiazolo[5,4-b]pyridin-5-yl}-N-{4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromet hyl)phenyl}benzamide, GLYCEROL, ... | 著者 | Weisberg, E, Choi, H.G, Seeliger, M, Gray, N, Griffin, J.D. | 登録日 | 2012-02-01 | 公開日 | 2012-02-15 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Discovery of a Small-Molecule Type II Inhibitor of Wild-Type and Gatekeeper Mutants of Bcr-Abl, Pdgfralpha, Kit, and Src Kinases: Novel Type II Inhibitor of Gatekeeper Mutants. Blood, 115, 2010
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7DTK
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7DTJ
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3C0C
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6WQL
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6WQJ
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3RL7
| Crystal structure of hDLG1-PDZ1 complexed with APC | 分子名称: | 11-mer peptide from Adenomatous polyposis coli protein, Disks large homolog 1 | 著者 | Zhang, Z, Li, H, Wu, G. | 登録日 | 2011-04-19 | 公開日 | 2011-12-14 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Molecular basis for the recognition of adenomatous polyposis coli by the Discs Large 1 protein. Plos One, 6, 2011
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3RES
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3KU0
| Structure of GAP31 with adenine at its binding pocket | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENINE, Ribosome-inactivating protein gelonin | 著者 | Kong, X.-P. | 登録日 | 2009-11-26 | 公開日 | 2010-01-26 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | A new activity of anti-HIV and anti-tumor protein GAP31: DNA adenosine glycosidase--structural and modeling insight into its functions. Biochem.Biophys.Res.Commun., 391, 2010
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3SRQ
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4MO7
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3SRS
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3TUO
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7XP6
| Cryo-EM structure of a class T GPCR in active state | 分子名称: | Endoglucanase H,Taste receptor type 2 member 46,Endoglucanase H,Taste receptor type 2 member 46,Bitter taste receptor T2R46, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Liu, Z.J, Hua, T, Xu, W.X, Wu, L.J. | 登録日 | 2022-05-03 | 公開日 | 2022-10-12 | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | 主引用文献 | Structural basis for strychnine activation of human bitter taste receptor TAS2R46. Science, 377, 2022
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7XP4
| Cryo-EM structure of a class T GPCR in apo state | 分子名称: | Endoglucanase H,Taste receptor type 2 member 46,Endoglucanase H,Taste receptor type 2 member 46,Bitter taste receptor T2R46, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Liu, Z.J, Hua, T, Xu, W.X, Wu, L.J. | 登録日 | 2022-05-03 | 公開日 | 2022-10-12 | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | 主引用文献 | Structural basis for strychnine activation of human bitter taste receptor TAS2R46. Science, 377, 2022
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7XP5
| Cryo-EM structure of a class T GPCR in ligand-free state | 分子名称: | Endoglucanase H,Taste receptor type 2 member 46,Bitter taste receptor T2R46, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Liu, Z.J, Hua, T, Xu, W.X, Wu, L.J. | 登録日 | 2022-05-03 | 公開日 | 2022-10-12 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | 主引用文献 | Structural basis for strychnine activation of human bitter taste receptor TAS2R46. Science, 377, 2022
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2L3T
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3KTZ
| Structure of GAP31 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Ribosome-inactivating protein gelonin | 著者 | Kong, X.-P. | 登録日 | 2009-11-26 | 公開日 | 2010-01-26 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | A new activity of anti-HIV and anti-tumor protein GAP31: DNA adenosine glycosidase--structural and modeling insight into its functions. Biochem.Biophys.Res.Commun., 391, 2010
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2K3Q
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2K3P
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2NB4
| Solution structure of Q388A3 PDZ domain | 分子名称: | Putative uncharacterized protein | 著者 | Mei, S. | 登録日 | 2016-01-24 | 公開日 | 2016-02-24 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of Q388A3 PDZ domain from Trypanosoma brucei J.Struct.Biol., 194, 2016
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2N7S
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8I4V
| Cryo-EM structure of 5-subunit Smc5/6 arm region | 分子名称: | DNA repair protein KRE29, E3 SUMO-protein ligase MMS21, Structural maintenance of chromosomes protein 5, ... | 著者 | Qian, L, Jun, Z, Xiang, Z, Cheng, T, Zhaoning, W, Zhenguo, C, Wang, L. | 登録日 | 2023-01-21 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (5.97 Å) | 主引用文献 | Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms. Nat.Struct.Mol.Biol., 2024
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5B7W
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