7T4K
| Structure of dimeric phosphorylated Pediculus humanus (Ph) PINK1 with kinked alpha-C helix in chain B | 分子名称: | Serine/threonine-protein kinase PINK1, putative | 著者 | Gan, Z.Y, Leis, A, Dewson, G, Glukhova, A, Komander, D. | 登録日 | 2021-12-10 | 公開日 | 2022-01-12 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | 主引用文献 | Activation mechanism of PINK1. Nature, 602, 2022
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6Q2Y
| Crystal structure of NDM-1 beta-lactamase in complex with broad spectrum boronic inhibitor cpd3 | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, Metallo-beta-lactamase type 2, ... | 著者 | Maso, L, Quotadamo, A, Bellio, P, Montanari, M, Venturelli, A, Celenza, G, Costi, M.P, Tondi, D, Cendron, L. | 登録日 | 2018-12-03 | 公開日 | 2019-04-24 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1 Å) | 主引用文献 | X-ray Crystallography Deciphers the Activity of Broad-Spectrum Boronic Acid beta-Lactamase Inhibitors. Acs Med.Chem.Lett., 10, 2019
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7T4N
| Structure of dimeric unphosphorylated Pediculus humanus (Ph) PINK1 D357A mutant | 分子名称: | Serine/threonine-protein kinase PINK1, putative | 著者 | Gan, Z.Y, Leis, A, Dewson, G, Glukhova, A, Komander, D. | 登録日 | 2021-12-10 | 公開日 | 2022-01-12 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (2.35 Å) | 主引用文献 | Activation mechanism of PINK1. Nature, 602, 2022
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7SXX
| Cryo-EM structure of the SARS-CoV-2 D614G mutant spike protein ectodomain bound to human ACE2 ectodomain (global refinement) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | 著者 | Zhu, X, Mannar, D, Saville, J.W, Srivastava, S.S, Berezuk, A.M, Zhou, S, Tuttle, K.S, Kim, A, Li, W, Dimitrov, D.S, Subramaniam, S. | 登録日 | 2021-11-24 | 公開日 | 2021-12-29 | 最終更新日 | 2022-01-05 | 実験手法 | ELECTRON MICROSCOPY (2.66 Å) | 主引用文献 | Structural analysis of receptor binding domain mutations in SARS-CoV-2 variants of concern that modulate ACE2 and antibody binding. Cell Rep, 37, 2021
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6Q28
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6Q45
| F1-ATPase from Fusobacterium nucleatum | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | 著者 | Petri, J, Nakatani, Y, Montgomery, M.G, Ferguson, S.A, Aragao, D, Leslie, A.G.W, Heikal, A, Walker, J.E, Cook, G.M. | 登録日 | 2018-12-05 | 公開日 | 2019-07-10 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Structure of F1-ATPase from the obligate anaerobe Fusobacterium nucleatum. Open Biology, 9, 2019
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6Q6P
| Antarctic fish cytoglobin 1 from D.mawsoni | 分子名称: | Cytoglobin, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Giordano, D, Pesce, A, Vermeylen, S, Abbruzzetti, S, Nardini, M, Marchesani, F, Berghmans, H, Seira, C, Bruno, S, Luque, F.J, di Prisco, G, Ascenzi, P, Dewilde, S, Bolognesi, M, Viappiani, C, Verde, C. | 登録日 | 2018-12-11 | 公開日 | 2020-01-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural and functional properties of Antarctic fish cytoglobins-1: Cold-reactivity in multi-ligand reactions. Comput Struct Biotechnol J, 18, 2020
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4KM4
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6Q61
| Pore-modulating toxins exploit inherent slow inactivation to block K+ channels | 分子名称: | Kunitz-type conkunitzin-S1, SULFATE ION | 著者 | Karbat, I, Gueta, H, Fine, S, Szanto, T, Hamer-Rogotner, S, Dym, O, Frolow, F, Gordon, D, Panyi, G, Gurevitz, M, Reuveny, E. | 登録日 | 2018-12-10 | 公開日 | 2019-08-21 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Pore-modulating toxins exploit inherent slow inactivation to block K+channels. Proc.Natl.Acad.Sci.USA, 116, 2019
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7T4L
| Structure of dimeric phosphorylated Pediculus humanus (Ph) PINK1 with extended alpha-C helix in chain B | 分子名称: | Serine/threonine-protein kinase PINK1, putative | 著者 | Gan, Z.Y, Leis, A, Dewson, G, Glukhova, A, Komander, D. | 登録日 | 2021-12-10 | 公開日 | 2022-01-12 | 最終更新日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | 主引用文献 | Activation mechanism of PINK1. Nature, 602, 2022
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6Q7G
| Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with the NVP-BHG712 derivative ATHA01 | 分子名称: | 3-[(4-imidazol-1-yl-6-morpholin-4-yl-1,3,5-triazin-2-yl)amino]-4-methyl-~{N}-[3-(trifluoromethyl)phenyl]benzamide, Ephrin type-A receptor 2 | 著者 | Kudlinzki, D, Troester, A, Witt, K, Linhard, V.L, Gande, S.L, Saxena, K, Schwalbe, H. | 登録日 | 2018-12-13 | 公開日 | 2020-01-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.047 Å) | 主引用文献 | Effects of NVP-BHG712 chemical modifications on EPHA2 binding and affinity To Be Published
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6Q7B
| Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with the NVP-BHG712 derivative ATDL09 | 分子名称: | 3-[[4-imidazol-1-yl-6-[(3~{S})-3-oxidanylpyrrolidin-1-yl]-1,3,5-triazin-2-yl]amino]-4-methyl-~{N}-[3-(trifluoromethyl)phenyl]benzamide, Ephrin type-A receptor 2 | 著者 | Kudlinzki, D, Troester, A, Witt, K, Linhard, V.L, Gande, S.L, Saxena, K, Schwalbe, H. | 登録日 | 2018-12-13 | 公開日 | 2020-01-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.009 Å) | 主引用文献 | Effects of NVP-BHG712 chemical modifications on EPHA2 binding and affinity To Be Published
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7SLZ
| CRYSTAL STRUCTURE OF GID4 IN COMPLEX WITH BPF023596 | 分子名称: | Glucose-induced degradation protein 4 homolog, N-[(1s,4s)-4-(1H-benzimidazol-2-yl)cyclohexyl]-N~2~-[(1H-indol-2-yl)methyl]glycinamide | 著者 | Song, X, Dong, A, Calabrese, M, Wang, F, Owen, D, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2021-10-25 | 公開日 | 2022-01-19 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | CRYSTAL STRUCTURE OF GID4 IN COMPLEX WITH BPF023596 To Be Published
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6Q7S
| ERK2 mini-fragment binding | 分子名称: | Mitogen-activated protein kinase 1, PHENOL, SULFATE ION | 著者 | O'Reilly, M, Cleasby, A, Davies, T.G, Hall, R, Ludlow, F, Murray, C.W, Tisi, D, Jhoti, H. | 登録日 | 2018-12-13 | 公開日 | 2019-06-26 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design. Drug Discov Today, 24, 2019
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6Q83
| Crystal structure of the biportin Pdr6 in complex with UBC9 | 分子名称: | Importin beta-like protein KAP122, UBC9 | 著者 | Aksu, M, Trakhanov, S, Vera-Rodriguez, A, Gorlich, D. | 登録日 | 2018-12-14 | 公開日 | 2019-05-01 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (4.53 Å) | 主引用文献 | Structural basis for the nuclear import and export functions of the biportin Pdr6/Kap122. J.Cell Biol., 218, 2019
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4KR4
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7T4M
| Structure of dodecameric unphosphorylated Pediculus humanus (Ph) PINK1 D357A mutant | 分子名称: | Serine/threonine-protein kinase PINK1, putative | 著者 | Gan, Z.Y, Leis, A, Dewson, G, Glukhova, A, Komander, D. | 登録日 | 2021-12-10 | 公開日 | 2022-01-12 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (2.48 Å) | 主引用文献 | Activation mechanism of PINK1. Nature, 602, 2022
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6QBO
| structure of the core domaine of Knr4, an intrinsically disordered protein from Saccharomyces cerevisiae - mutant S203A | 分子名称: | Cell wall assembly regulator SMI1 | 著者 | Ramos, N, Batista, M, Francois, J.M, Mourey, L, Maveyraud, L, Zerbib, D. | 登録日 | 2018-12-21 | 公開日 | 2020-01-29 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | structure of the core domaine of Knr4, an intrinsically disordered protein from Saccharomyces cerevisiae - mutant S203A To Be Published
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6QEH
| CRYSTAL STRUCTURE OF HUMAN METHIONINE AMINOPEPTIDASE-2 IN COMPLEX WITH AN INHIBITOR 5-Chloro-quinolin-8-ol | 分子名称: | 5-chloranylquinolin-8-ol, GLYCEROL, MANGANESE (II) ION, ... | 著者 | Musil, D, Heinrich, T, Lehmann, M. | 登録日 | 2019-01-07 | 公開日 | 2019-05-01 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Discovery and Structure-Based Optimization of Next-Generation Reversible Methionine Aminopeptidase-2 (MetAP-2) Inhibitors. J.Med.Chem., 62, 2019
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6QG4
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6QEJ
| CRYSTAL STRUCTURE OF HUMAN METHIONINE AMINOPEPTIDASE-2 IN COMPLEX WITH AN INHIBITOR Thiophene-2-sulfonic acid (4-fluoro-benzyl)-(4H-[1,2,4]triazol-3-ylmethyl)-amide | 分子名称: | 1,2-ETHANEDIOL, MANGANESE (II) ION, Methionine aminopeptidase 2, ... | 著者 | Musil, D, Heinrich, T, Lehmann, M. | 登録日 | 2019-01-07 | 公開日 | 2019-05-01 | 最終更新日 | 2019-06-05 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | Discovery and Structure-Based Optimization of Next-Generation Reversible Methionine Aminopeptidase-2 (MetAP-2) Inhibitors. J.Med.Chem., 62, 2019
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6QFR
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6QJS
| Crystal structure of a DNA dodecamer containing a tetramethylpiperidinoxyl (nitroxide) spin label | 分子名称: | COBALT HEXAMMINE(III), DNA (5'-D(P*GP*CP*AP*AP*AP*TP*TP*(S6M)P*GP*CP*G)-3') | 著者 | Hardwick, J.S, Haugland, M.M, Ptchelkine, D, Brown, T, Anderson, E.E. | 登録日 | 2019-01-24 | 公開日 | 2020-02-12 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | 2'-Alkynyl spin-labelling is a minimally perturbing tool for DNA structural analysis. Nucleic Acids Res., 48, 2020
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6Q5V
| 1-Cys SiPrx, a Prx6-family 1-Cys peroxiredoxin of the thermoacidophilic archaeon Sulfolobus islandicus | 分子名称: | Peroxiredoxin | 著者 | Stroobants, S, Maes, D, Peeters, E, van Molle, I. | 登録日 | 2018-12-09 | 公開日 | 2019-05-29 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.747 Å) | 主引用文献 | Structure of the Prx6-subfamily 1-Cys peroxiredoxin from Sulfolobus islandicus. Acta Crystallogr.,Sect.F, 75, 2019
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6Q82
| Crystal structure of the biportin Pdr6 in complex with RanGTP | 分子名称: | GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, Importin beta-like protein KAP122, ... | 著者 | Aksu, M, Vera-Rodriguez, A, Trakhanov, S, Gorlich, D. | 登録日 | 2018-12-14 | 公開日 | 2019-05-01 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (2.994 Å) | 主引用文献 | Structural basis for the nuclear import and export functions of the biportin Pdr6/Kap122. J.Cell Biol., 218, 2019
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