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7DZ2
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BU of 7dz2 by Molmil
Crystal structures of D-allulose 3-epimerase from Sinorhizobium fredii
分子名称: D-tagatose 3-epimerase, MAGNESIUM ION, SULFATE ION
著者Zhu, Z.L, Miyakawa, T, Tanokura, M, Lu, F.P, Qin, H.-M.
登録日2021-01-23
公開日2022-08-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Substantial Improvement of an Epimerase for the Synthesis of D-Allulose by Biosensor-Based High-Throughput Microdroplet Screening
Angew.Chem.Int.Ed.Engl., 2023
7DZ3
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BU of 7dz3 by Molmil
Crystal structures of D-allulose 3-epimerase with D-fructose from Sinorhizobium fredii
分子名称: D-fructose, D-tagatose 3-epimerase, MAGNESIUM ION
著者Zhu, Z.L, Miyakawa, T, Tanokura, M, Lu, F.P, Qin, H.-M.
登録日2021-01-23
公開日2022-08-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Substantial Improvement of an Epimerase for the Synthesis of D-Allulose by Biosensor-Based High-Throughput Microdroplet Screening
Angew.Chem.Int.Ed.Engl., 2023
7DZ4
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BU of 7dz4 by Molmil
Crystal structures of D-allulose 3-epimerase with D-tagatose from Sinorhizobium fredii
分子名称: D-tagatose, D-tagatose 3-epimerase, MAGNESIUM ION
著者Zhu, Z.L, Miyakawa, T, Tanokura, M, Lu, F.P, Qin, H.-M.
登録日2021-01-23
公開日2022-08-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Substantial Improvement of an Epimerase for the Synthesis of D-Allulose by Biosensor-Based High-Throughput Microdroplet Screening
Angew.Chem.Int.Ed.Engl., 2023
7DZ6
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BU of 7dz6 by Molmil
Crystal structures of D-allulose 3-epimerase with D-allulose from Sinorhizobium fredii
分子名称: D-psicose, D-tagatose 3-epimerase, MAGNESIUM ION
著者Zhu, Z.L, Miyakawa, T, Tanokura, M, Lu, F.P, Qin, H.-M.
登録日2021-01-23
公開日2022-08-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Substantial Improvement of an Epimerase for the Synthesis of D-Allulose by Biosensor-Based High-Throughput Microdroplet Screening
Angew.Chem.Int.Ed.Engl., 2023
7DZ5
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BU of 7dz5 by Molmil
Crystal structures of D-allulose 3-epimerase with D-sorbose from Sinorhizobium fredii
分子名称: D-sorbose, D-tagatose 3-epimerase, MAGNESIUM ION, ...
著者Zhu, Z.L, Miyakawa, T, Tanokura, M, Lu, F.P, Qin, H.-M.
登録日2021-01-23
公開日2022-08-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Substantial Improvement of an Epimerase for the Synthesis of D-Allulose by Biosensor-Based High-Throughput Microdroplet Screening
Angew.Chem.Int.Ed.Engl., 2023
6EW7
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BU of 6ew7 by Molmil
Crystal structure of the BCL6 BTB domain in complex with anilinopyrimidine ligand
分子名称: 2-chloranyl-4-[[5-chloranyl-4-[(4-fluorophenyl)amino]pyrimidin-2-yl]amino]benzoic acid, B-cell lymphoma 6 protein, CHLORIDE ION
著者Robb, G, Ferguson, A, Hargreaves, D.
登録日2017-11-03
公開日2018-10-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Development of a Novel B-Cell Lymphoma 6 (BCL6) PROTAC To Provide Insight into Small Molecule Targeting of BCL6.
ACS Chem. Biol., 13, 2018
8J3V
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BU of 8j3v by Molmil
Structure of the transmembrane domain of human PD-L2
分子名称: Programmed cell death 1 ligand 2
著者OuYang, B, Zhang, Y.
登録日2023-04-18
公開日2024-03-13
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Deciphering Cholesterol's Role in PD-L2 Stability: A Distinct Regulatory Mechanism From PD-L1.
J.Mol.Biol., 436, 2024
7FEJ
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BU of 7fej by Molmil
Complex of FMDV A/AF/72 and bovine neutralizing scFv antibody R55
分子名称: A/AF/72 VP1, A/AF/72 VP2, A/AF/72 VP3, ...
著者He, Y, Li, K, Lou, Z.
登録日2021-07-20
公開日2021-09-29
最終更新日2022-02-16
実験手法ELECTRON MICROSCOPY (3.91 Å)
主引用文献Structures of Foot-and-Mouth Disease Virus with Bovine Neutralizing Antibodies Reveal the Determinant of Intraserotype Cross-Neutralization.
J.Virol., 95, 2021
7FEI
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BU of 7fei by Molmil
Complex of FMDV A/WH/CHA/09 and bovine neutralizing scFv antibody R55
分子名称: Capsid protein VP0, IG HEAVY CHAIN VARIABLE REGION, IG LAMDA CHAIN VARIABLE REGION
著者He, Y, Li, K, Lou, Z.
登録日2021-07-20
公開日2021-09-29
最終更新日2022-02-16
実験手法ELECTRON MICROSCOPY (3.91 Å)
主引用文献Structures of Foot-and-Mouth Disease Virus with Bovine Neutralizing Antibodies Reveal the Determinant of Intraserotype Cross-Neutralization.
J.Virol., 95, 2021
7CNC
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BU of 7cnc by Molmil
cystal structure of human ERH in complex with DGCR8
分子名称: Enhancer of rudimentary homolog, Microprocessor complex subunit DGCR8
著者Li, F, Shen, S.
登録日2020-07-30
公開日2020-10-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献ERH facilitates microRNA maturation through the interaction with the N-terminus of DGCR8.
Nucleic Acids Res., 48, 2020
8KB1
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BU of 8kb1 by Molmil
Crystal structure of 11JD
分子名称: Beta2-microglobulin, MHC class I antigen, peptide of AIV
著者Tang, Z, Zhang, N.
登録日2023-08-03
公開日2024-05-29
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献The impact of micropolymorphism in Anpl-UAA on structural stability and peptide presentation.
Int.J.Biol.Macromol., 267, 2024
8KB0
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BU of 8kb0 by Molmil
Crystal structure of 01JD-AEAIIVAMV
分子名称: Beta2-microglobulin, MHC class I antigen alpha chain, peptide of AIV
著者Tang, Z, Zhang, N.
登録日2023-08-03
公開日2024-05-29
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献The impact of micropolymorphism in Anpl-UAA on structural stability and peptide presentation.
Int.J.Biol.Macromol., 267, 2024
5UOO
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BU of 5uoo by Molmil
BRD4 bromodomain 2 in complex with CD161
分子名称: 7-(3,5-dimethyl-1,2-oxazol-4-yl)-6-methoxy-2-methyl-4-(quinolin-4-yl)-9H-pyrimido[4,5-b]indole, Bromodomain-containing protein 4
著者Meagher, J.L, Stuckey, J.A.
登録日2017-02-01
公開日2017-05-17
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Structure-Based Discovery of 4-(6-Methoxy-2-methyl-4-(quinolin-4-yl)-9H-pyrimido[4,5-b]indol-7-yl)-3,5-dimethylisoxazole (CD161) as a Potent and Orally Bioavailable BET Bromodomain Inhibitor.
J. Med. Chem., 60, 2017
5X0S
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BU of 5x0s by Molmil
Solution NMR structure of peptide toxin SsTx from Scolopendra subspinipes mutilans
分子名称: SsTx
著者Wu, F, Luo, L, Qu, D, Zhang, L, Tian, C, Lai, R.
登録日2017-01-23
公開日2018-01-24
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Centipedes subdue giant prey by blocking KCNQ channels
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8HCO
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BU of 8hco by Molmil
Substrate-engaged TOM complex from yeast
分子名称: Mitochondrial import receptor subunit TOM22, Mitochondrial import receptor subunit TOM40, Mitochondrial import receptor subunit TOM5, ...
著者Zhou, X.Y, Yang, Y.Q, Wang, G.P, Wang, S.S.
登録日2022-11-02
公開日2023-09-13
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Molecular pathway of mitochondrial preprotein import through the TOM-TIM23 supercomplex.
Nat.Struct.Mol.Biol., 30, 2023
7LQH
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BU of 7lqh by Molmil
Cryo-EM of KFE8 thinner nanotube (class 2, 2-sub-1)
分子名称: KFE8 peptide
著者Wang, F, Gnewou, O.M, Egelman, E.H, Conticello, V.P.
登録日2021-02-13
公開日2021-06-30
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Deterministic chaos in the self-assembly of beta sheet nanotubes from an amphipathic oligopeptide.
Matter, 4, 2021
7LQF
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BU of 7lqf by Molmil
Cryo-EM of KFE8 ribbon filament
分子名称: KFE8 peptide
著者Wang, F, Gnewou, O.M, Egelman, E.H, Conticello, V.P.
登録日2021-02-13
公開日2021-06-30
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Deterministic chaos in the self-assembly of beta sheet nanotubes from an amphipathic oligopeptide.
Matter, 4, 2021
7LQI
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BU of 7lqi by Molmil
Cryo-EM of KFE8 thicker nanotube
分子名称: KFE8 peptide
著者Wang, F, Gnewou, O.M, Egelman, E.H, Conticello, V.P.
登録日2021-02-13
公開日2021-06-30
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Deterministic chaos in the self-assembly of beta sheet nanotubes from an amphipathic oligopeptide.
Matter, 4, 2021
7LQG
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BU of 7lqg by Molmil
Cryo-EM of the KFE8 thinner nanotube (class 1, C2)
分子名称: KFE8 peptide
著者Wang, F, Gnewou, O.M, Egelman, E.H, Conticello, V.P.
登録日2021-02-13
公開日2021-06-30
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Deterministic chaos in the self-assembly of beta sheet nanotubes from an amphipathic oligopeptide.
Matter, 4, 2021
7LQE
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BU of 7lqe by Molmil
Cryo-EM of 1-protofilament of the KFE8 thinner nanotube
分子名称: KFE8 peptide
著者Wang, F, Gnewou, O.M, Egelman, E.H, Conticello, V.P.
登録日2021-02-13
公開日2021-06-30
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Deterministic chaos in the self-assembly of beta sheet nanotubes from an amphipathic oligopeptide.
Matter, 4, 2021
5MLY
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BU of 5mly by Molmil
Closed loop conformation of PhaZ7 Y105E mutant
分子名称: PHB depolymerase PhaZ7
著者Kellici, T, Mavromoustakos, T, Jendrossek, D, Papageorgiou, A.C.
登録日2016-12-08
公開日2017-05-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.598 Å)
主引用文献Crystal structure analysis, covalent docking, and molecular dynamics calculations reveal a conformational switch in PhaZ7 PHB depolymerase.
Proteins, 85, 2017
6D9X
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BU of 6d9x by Molmil
Discovery of Potent 2-Aryl-6,7-Dihydro-5HPyrrolo[ 1,2-a]imidazoles as WDR5 WIN-site Inhibitors Using Fragment-Based Methods and Structure-Based Design
分子名称: 2-phenyl-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole, SODIUM ION, WD repeat-containing protein 5
著者Phan, J, Fesik, S.W.
登録日2018-04-30
公開日2018-09-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Discovery of Potent 2-Aryl-6,7-dihydro-5 H-pyrrolo[1,2- a]imidazoles as WDR5-WIN-Site Inhibitors Using Fragment-Based Methods and Structure-Based Design.
J. Med. Chem., 61, 2018
5UFI
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BU of 5ufi by Molmil
DCN1 bound to DI-591
分子名称: DCN1-like protein 1, N-[(1S)-1-cyclohexyl-2-{[3-(morpholin-4-yl)propanoyl]amino}ethyl]-N~2~-propanoyl-3-[6-(propan-2-yl)-1,3-benzothiazol-2-yl]-L-alaninamide
著者Stuckey, J.
登録日2017-01-04
公開日2017-11-01
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献A potent small-molecule inhibitor of the DCN1-UBC12 interaction that selectively blocks cullin 3 neddylation.
Nat Commun, 8, 2017
4U6W
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BU of 4u6w by Molmil
HsMetAP (F220M) in complex with 1-amino-2-propylpentyl]phosphonic acid
分子名称: COBALT (II) ION, GLYCEROL, Methionine aminopeptidase 1, ...
著者Arya, T, Addlagatta, A.
登録日2014-07-30
公開日2015-03-25
最終更新日2019-11-20
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Identification of the Molecular Basis of Inhibitor Selectivity between the Human and Streptococcal Type I Methionine Aminopeptidases
J.Med.Chem., 58, 2015
4U71
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BU of 4u71 by Molmil
HsMetAP(F309M) IN COMPLEX WITH 1- amino(cyclohexyl)methy)phosphonic acid
分子名称: COBALT (II) ION, GLYCEROL, Methionine aminopeptidase 1, ...
著者Arya, T, Addlagatta, A.
登録日2014-07-30
公開日2015-03-25
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Identification of the Molecular Basis of Inhibitor Selectivity between the Human and Streptococcal Type I Methionine Aminopeptidases
J.Med.Chem., 58, 2015

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