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3UA0
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BU of 3ua0 by Molmil
N-Terminal Domain of Bombyx mori Fibroin Mediates the Assembly of Silk in Response to pH Decrease
分子名称: Fibroin heavy chain
著者He, Y.-X, Zhang, N.-N, Chen, B.-Y, Li, W.-F, Chen, Y.-X, Zhou, C.-Z.
登録日2011-10-20
公開日2012-03-28
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献N-Terminal Domain of Bombyx mori Fibroin Mediates the Assembly of Silk in Response to pH Decrease.
J.Mol.Biol., 418, 2012
3FH5
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BU of 3fh5 by Molmil
Leukotriene A4 Hydrolase complexed with inhibitor (2R)-2-[(4-benzylphenoxy)methyl]pyrrolidine.
分子名称: (2R)-2-[(4-benzylphenoxy)methyl]pyrrolidine, ACETATE ION, GLYCEROL, ...
著者Mamat, B, Davies, D.R.
登録日2008-12-08
公開日2010-01-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Discovery of 4-[(2S)-2-{[4-(4-chlorophenoxy)phenoxy]methyl}-1-pyrrolidinyl]butanoic acid (DG-051) as a novel leukotriene A4 hydrolase inhibitor of leukotriene B4 biosynthesis.
J.Med.Chem., 53, 2010
3FH8
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BU of 3fh8 by Molmil
Leukotriene A4 Hydrolase complexed with inhibitor 1-[2-(4-benzylphenoxy)ethyl]pyrrolidine.
分子名称: 1-[2-(4-benzylphenoxy)ethyl]pyrrolidine, ACETATE ION, IMIDAZOLE, ...
著者Mamat, B, Davies, D.R.
登録日2008-12-09
公開日2010-01-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Discovery of 4-[(2S)-2-{[4-(4-chlorophenoxy)phenoxy]methyl}-1-pyrrolidinyl]butanoic acid (DG-051) as a novel leukotriene A4 hydrolase inhibitor of leukotriene B4 biosynthesis.
J.Med.Chem., 53, 2010
4DCH
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BU of 4dch by Molmil
Insights into Glucokinase Activation Mechanism: Observation of Multiple Distinct Protein Conformations
分子名称: (2R)-3-cyclopentyl-2-[4-(methylsulfonyl)phenyl]-N-(1,3-thiazol-2-yl)propanamide, Glucokinase, IODIDE ION, ...
著者Greasley, S.E, Hickey, M, Feng, J, Garcia, E.
登録日2012-01-17
公開日2012-02-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Insights into Mechanism of Glucokinase Activation: OBSERVATION OF MULTIPLE DISTINCT PROTEIN CONFORMATIONS.
J.Biol.Chem., 287, 2012
3FHE
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BU of 3fhe by Molmil
Leukotriene A4 Hydrolase complexed with inhibitor N-[3-(4-benzylphenoxy)propyl]-N-methyl-beta-alanine.
分子名称: ACETATE ION, IMIDAZOLE, Leukotriene A-4 hydrolase, ...
著者Mamat, B, Davies, D.R.
登録日2008-12-09
公開日2010-01-05
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Discovery of 4-[(2S)-2-{[4-(4-chlorophenoxy)phenoxy]methyl}-1-pyrrolidinyl]butanoic acid (DG-051) as a novel leukotriene A4 hydrolase inhibitor of leukotriene B4 biosynthesis.
J.Med.Chem., 53, 2010
8WQF
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BU of 8wqf by Molmil
cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CUX1 (conformation 2)
分子名称: Cullin-2, E3 ubiquitin-protein ligase RBX1, N-terminally processed, ...
著者Chen, X, Zhang, K, Xu, C.
登録日2023-10-11
公開日2024-04-03
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.27 Å)
主引用文献Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
8WQE
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BU of 8wqe by Molmil
Cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CUX1 (conformation 1)
分子名称: Cullin-2, E3 ubiquitin-protein ligase RBX1, N-terminally processed, ...
著者Chen, X, Zhang, K, Xu, C.
登録日2023-10-11
公開日2024-04-03
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
8WQD
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BU of 8wqd by Molmil
Local refinement of FEM1B bound with the C-degron of CCC89
分子名称: Coiled-coil domain-containing protein 89, Protein fem-1 homolog B
著者Chen, X, Zhang, K, Xu, C.
登録日2023-10-11
公開日2024-04-03
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.55 Å)
主引用文献Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
8WQC
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BU of 8wqc by Molmil
cryo-EM structure of neddylated CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CDK5R1
分子名称: Cullin-2, E3 ubiquitin-protein ligase RBX1, N-terminally processed, ...
著者Chen, X, Zhang, K, Xu, C.
登録日2023-10-11
公開日2024-04-03
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
8WQG
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BU of 8wqg by Molmil
cryo-EM structure of neddylated CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 1)
分子名称: Cullin-2, E3 ubiquitin-protein ligase RBX1, N-terminally processed, ...
著者Chen, X, Zhang, K, Xu, C.
登録日2023-10-11
公開日2024-04-03
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (4.09 Å)
主引用文献Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
8WQI
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BU of 8wqi by Molmil
Local refinement of FEM1B bound with the C-degron of CUX1
分子名称: Protein CASP, Protein fem-1 homolog B
著者Chen, X, Zhang, K, Xu, C.
登録日2023-10-11
公開日2024-04-03
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
8WQA
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BU of 8wqa by Molmil
Cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 1)
分子名称: Coiled-coil domain-containing protein 89, Cullin-2, E3 ubiquitin-protein ligase RBX1, ...
著者Chen, X, Zhang, K, Xu, C.
登録日2023-10-11
公開日2024-04-03
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.39 Å)
主引用文献Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
8WQH
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BU of 8wqh by Molmil
cryo-EM structure of neddylated CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 2)
分子名称: Coiled-coil domain-containing protein 89, Cullin-2, E3 ubiquitin-protein ligase RBX1, ...
著者Chen, X, Zhang, K, Xu, C.
登録日2023-10-11
公開日2024-04-03
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.44 Å)
主引用文献Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
8WQB
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BU of 8wqb by Molmil
Cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 2)
分子名称: Coiled-coil domain-containing protein 89, Cullin-2, E3 ubiquitin-protein ligase RBX1, ...
著者Chen, X, Zhang, K, Xu, C.
登録日2023-10-11
公開日2024-04-03
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.37 Å)
主引用文献Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
3FTZ
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BU of 3ftz by Molmil
Leukotriene A4 hydrolase in complex with fragment 2-(pyridin-3-ylmethoxy)aniline
分子名称: 2-(pyridin-3-ylmethoxy)aniline, ACETATE ION, IMIDAZOLE, ...
著者Davies, D.R.
登録日2009-01-13
公開日2010-01-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Discovery of 4-[(2S)-2-{[4-(4-chlorophenoxy)phenoxy]methyl}-1-pyrrolidinyl]butanoic acid (DG-051) as a novel leukotriene A4 hydrolase inhibitor of leukotriene B4 biosynthesis.
J.Med.Chem., 53, 2010
3FUL
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BU of 3ful by Molmil
Leukotriene A4 hydrolase in complex with pyridin-4-yl[4-(2-pyrrolidin-1-ylethoxy)phenyl]methanone
分子名称: IMIDAZOLE, Leukotriene A-4 hydrolase, YTTERBIUM (III) ION, ...
著者Davies, D.R.
登録日2009-01-14
公開日2010-01-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Discovery of 4-[(2S)-2-{[4-(4-chlorophenoxy)phenoxy]methyl}-1-pyrrolidinyl]butanoic acid (DG-051) as a novel leukotriene A4 hydrolase inhibitor of leukotriene B4 biosynthesis.
J.Med.Chem., 53, 2010
7X4B
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BU of 7x4b by Molmil
Crystal Structure of An Anti-CRISPR Protein
分子名称: Anti-CRISPR protein (AcrIIC1), SULFATE ION
著者Hu, J, Zhang, S, Gao, J.Y, Liu, X, Liu, J.
登録日2022-03-02
公開日2022-10-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献A redox switch regulates the assembly and anti-CRISPR activity of AcrIIC1.
Nat Commun, 13, 2022
7X7T
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BU of 7x7t by Molmil
Cryo-EM structure of SARS-CoV-2 spike protein in complex with three nAbs X01, X10 and X17
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, X01 heavy chain, ...
著者Sun, H, Liu, L, Zheng, Q, Li, S, Zhang, T, Xia, N.
登録日2022-03-10
公開日2022-08-17
最終更新日2022-11-23
実験手法ELECTRON MICROSCOPY (3.48 Å)
主引用文献The neutralizing breadth of antibodies targeting diverse conserved epitopes between SARS-CoV and SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 119, 2022
7X7V
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BU of 7x7v by Molmil
Cryo-EM structure of SARS-CoV spike protein in complex with three nAbs X01, X10 and X17
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, X01 heavy chain, ...
著者Sun, H, Liu, L, Zhang, T, Zheng, Q, Li, S, Xia, N.
登録日2022-03-10
公開日2022-08-17
最終更新日2022-11-23
実験手法ELECTRON MICROSCOPY (3.83 Å)
主引用文献The neutralizing breadth of antibodies targeting diverse conserved epitopes between SARS-CoV and SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 119, 2022
7X7U
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BU of 7x7u by Molmil
Cryo-EM structure of SARS-CoV-2 Delta variant spike protein in complex with three nAbs X01, X10 and X17
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, X01 heavy chain, ...
著者Sun, H, Liu, L, Zhang, T, Zheng, Q, Li, S, Xia, N.
登録日2022-03-10
公開日2022-08-17
最終更新日2022-11-23
実験手法ELECTRON MICROSCOPY (3.77 Å)
主引用文献The neutralizing breadth of antibodies targeting diverse conserved epitopes between SARS-CoV and SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 119, 2022
2PWX
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BU of 2pwx by Molmil
Crystal structure of G11A mutant of SARS-CoV 3C-like protease
分子名称: 3C-like proteinase
著者Chen, S, Hu, T, Jiang, H, Shen, X.
登録日2007-05-14
公開日2007-10-30
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Mutation of Gly-11 on the dimer interface results in the complete crystallographic dimer dissociation of severe acute respiratory syndrome coronavirus 3C-like protease: crystal structure with molecular dynamics simulations.
J.Biol.Chem., 283, 2008
3FH7
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BU of 3fh7 by Molmil
Leukotriene A4 Hydrolase complexed with inhibitor 4-[(2S)-2-{[4-(4-chlorophenoxy)phenoxy]methyl}pyrrolidin-1-yl]butanoate.
分子名称: 4-[(2S)-2-{[4-(4-chlorophenoxy)phenoxy]methyl}pyrrolidin-1-yl]butanoate, ACETATE ION, GLYCEROL, ...
著者Mamat, B, Davies, D.R.
登録日2008-12-08
公開日2010-01-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Discovery of 4-[(2S)-2-{[4-(4-chlorophenoxy)phenoxy]methyl}-1-pyrrolidinyl]butanoic acid (DG-051) as a novel leukotriene A4 hydrolase inhibitor of leukotriene B4 biosynthesis.
J.Med.Chem., 53, 2010
2LUY
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BU of 2luy by Molmil
Solution structure of the tandem zinc finger domain of fission yeast Stc1
分子名称: Meiotic chromosome segregation protein P8B7.28c, ZINC ION
著者He, C, Shi, Y, Bayne, E, Wu, J.
登録日2012-06-22
公開日2013-05-08
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural analysis of Stc1 provides insights into the coupling of RNAi and chromatin modification.
Proc.Natl.Acad.Sci.USA, 110, 2013
7VQ1
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BU of 7vq1 by Molmil
Structure of Apo-hsTRPM2 channel
分子名称: Transient receptor potential cation channel subfamily M member 2
著者Yu, X.F, Xie, Y, Zhang, X.K, Ma, C, Guo, J.T, Yang, F, Yang, W.
登録日2021-10-18
公開日2021-12-22
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.76 Å)
主引用文献Structural and functional basis of the selectivity filter as a gate in human TRPM2 channel.
Cell Rep, 37, 2021
7VQ2
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BU of 7vq2 by Molmil
Structure of Apo-hsTRPM2 channel TM domain
分子名称: Transient receptor potential cation channel subfamily M member 2
著者Yu, X.F, Xie, Y, Zhang, X.K, Ma, C, Guo, J.T, Yang, F, Yang, W.
登録日2021-10-18
公開日2021-12-22
実験手法ELECTRON MICROSCOPY (3.68 Å)
主引用文献Structural and functional basis of the selectivity filter as a gate in human TRPM2 channel.
Cell Rep, 37, 2021

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