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6KI7
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BU of 6ki7 by Molmil
Pyrophosphatase mutant K30R from Acinetobacter baumannii
分子名称: Inorganic pyrophosphatase
著者Su, J.
登録日2019-07-17
公開日2019-10-02
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Crystal Structures of Pyrophosphatase from Acinetobacter baumannii: Snapshots of Pyrophosphate Binding and Identification of a Phosphorylated Enzyme Intermediate.
Int J Mol Sci, 20, 2019
4KFV
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BU of 4kfv by Molmil
Structural insight into Golgi membrane stacking by GRASP65 and GRASP55
分子名称: CHLORIDE ION, Golgi reassembly-stacking protein 1, ZINC ION
著者Liu, X, Hu, J.
登録日2013-04-28
公開日2013-08-21
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural insight into Golgi membrane stacking by GRASP65 and GRASP55 proteins
J.Biol.Chem., 288, 2013
5J9F
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BU of 5j9f by Molmil
Human GAR transformylase in complex with GAR and (4-{[2-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)ethyl]amino}benzoyl)-L-glutamic acid (AGF183)
分子名称: GLYCINAMIDE RIBONUCLEOTIDE, N-(4-{[2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)ethyl]amino}benzene-1-carbonyl)-L-glutamic acid, Trifunctional purine biosynthetic protein adenosine-3
著者Wong, J, Deis, S.M, Dann III, C.E.
登録日2016-04-09
公開日2016-08-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Tumor Targeting with Novel 6-Substituted Pyrrolo [2,3-d] Pyrimidine Antifolates with Heteroatom Bridge Substitutions via Cellular Uptake by Folate Receptor alpha and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide Biosynthesis.
J.Med.Chem., 59, 2016
6K21
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BU of 6k21 by Molmil
Pyrophosphatase from Acinetobacter baumannii
分子名称: Inorganic pyrophosphatase, MAGNESIUM ION, SODIUM ION
著者Su, J.
登録日2019-05-13
公開日2019-10-02
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structures of Pyrophosphatase from Acinetobacter baumannii: Snapshots of Pyrophosphate Binding and Identification of a Phosphorylated Enzyme Intermediate.
Int J Mol Sci, 20, 2019
6K27
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BU of 6k27 by Molmil
Pyrophosphatase with PPi from Acinetobacter baumannii
分子名称: DIPHOSPHATE, Inorganic pyrophosphatase, MAGNESIUM ION
著者Su, J.
登録日2019-05-13
公開日2019-10-02
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Crystal Structures of Pyrophosphatase from Acinetobacter baumannii: Snapshots of Pyrophosphate Binding and Identification of a Phosphorylated Enzyme Intermediate.
Int J Mol Sci, 20, 2019
6KI8
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BU of 6ki8 by Molmil
Pyrophosphatase mutant K149R from Acinetobacter baumannii
分子名称: DIPHOSPHATE, Inorganic pyrophosphatase, MAGNESIUM ION
著者Su, J.
登録日2019-07-17
公開日2019-10-02
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Crystal Structures of Pyrophosphatase from Acinetobacter baumannii: Snapshots of Pyrophosphate Binding and Identification of a Phosphorylated Enzyme Intermediate.
Int J Mol Sci, 20, 2019
6KJX
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BU of 6kjx by Molmil
Galectin-13 variant C138S
分子名称: Galactoside-binding soluble lectin 13
著者Su, J.
登録日2019-07-23
公開日2019-10-16
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Galectin-13/placental protein 13: redox-active disulfides as switches for regulating structure, function and cellular distribution.
Glycobiology, 30, 2020
6IH9
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BU of 6ih9 by Molmil
Adeno-Associated Virus 2 at 2.8 ang
分子名称: Capsid protein VP1
著者Lou, Z.Y, Zhang, R.
登録日2018-09-29
公開日2019-07-03
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Adeno-associated virus 2 bound to its cellular receptor AAVR.
Nat Microbiol, 4, 2019
4LBF
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BU of 4lbf by Molmil
Crystal structure of HUMAN ALPHA-DEFENSIN 1 (HNP1) I20A/L25A mutant
分子名称: GLYCEROL, Neutrophil defensin 1
著者Tolbert, W.D, Wu, X, Pazgier, M.
登録日2013-06-20
公開日2013-11-27
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Single, Double and Quadruple Alanine Substitutions at Oligomeric Interfaces Identify Hydrophobicity as the Key Determinant of Human Neutrophil Alpha Defensin HNP1 Function.
Plos One, 8, 2013
3CQ0
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BU of 3cq0 by Molmil
Crystal Structure of TAL2_YEAST
分子名称: 1,2-ETHANEDIOL, GLYCEROL, Putative transaldolase YGR043C, ...
著者Huang, H, Niu, L, Teng, M.
登録日2008-04-01
公開日2009-04-07
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The crystal structure and identification of NQM1/YGR043C, a transaldolase from Saccharomyces cerevisiae
Proteins, 73, 2008
4LB1
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BU of 4lb1 by Molmil
Crystal structure of human alpha-defensin 1 (HNP1) Y16A/F28A mutant
分子名称: Neutrophil defensin 1
著者Tolbert, W.D, Wu, X, Pazgier, M.
登録日2013-06-20
公開日2013-11-27
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Single, Double and Quadruple Alanine Substitutions at Oligomeric Interfaces Identify Hydrophobicity as the Key Determinant of Human Neutrophil Alpha Defensin HNP1 Function.
Plos One, 8, 2013
8HKH
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BU of 8hkh by Molmil
Crystal structure of the LC/A1-DARPin18 complex
分子名称: BoNT/A, Designed ankyrin repeat protein 18, ZINC ION
著者Wu, Y, Leka, O, Kammerer, R.
登録日2022-11-26
公開日2023-11-29
最終更新日2025-01-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A DARPin promotes faster onset of botulinum neurotoxin A1 action.
Nat Commun, 14, 2023
7BRS
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BU of 7brs by Molmil
E.coli beta-galactosidase (E537Q) in complex with fluorescent probe KSA02
分子名称: 8-[2-[(E)-2-[4-[(2S,3R,4S,5R,6R)-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxyphenyl]ethenyl]-3,3-dimethyl-indol-1-ium-1-yl]octanoic acid, Beta-galactosidase, DIMETHYL SULFOXIDE, ...
著者Chen, X, Hu, Y.L, Gao, Y, Yuan, R, Guo, Y.
登録日2020-03-30
公開日2021-03-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Two-Dimensional Design Strategy to Construct Smart Fluorescent Probes for the Precise Tracking of Senescence.
Angew.Chem.Int.Ed.Engl., 60, 2021
6M0A
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BU of 6m0a by Molmil
The heme-bound structure of the chloroplast protein At3g03890
分子名称: AT3G03890 protein, AZIDE ION, PROTOPORPHYRIN IX CONTAINING FE
著者Wang, J, Liu, L.
登録日2020-02-20
公開日2020-12-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Arabidopsis locus AT3G03890 encodes a dimeric beta-barrel protein implicated in heme degradation.
Biochem.J., 2020
6M09
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BU of 6m09 by Molmil
The ligand-free structure of the chloroplast protein At3g03890
分子名称: AT3G03890 protein
著者Wang, J, Liu, L.
登録日2020-02-20
公開日2020-12-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.101 Å)
主引用文献The Arabidopsis locus AT3G03890 encodes a dimeric beta-barrel protein implicated in heme degradation.
Biochem.J., 2020
9HCF
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BU of 9hcf by Molmil
Mouse mitoribosome large subunit assembly intermediate bound to NSUN4, METRF4, GTPBP7, GTPBP10 and the MALSU-L0R8F8-mtACP complex with uL16m, State B2 (SAMC knock-out)
分子名称: 16S rRNA (1432-MER), 5-cytosine rRNA methyltransferase NSUN4, Acyl carrier protein, ...
著者Singh, V, Rorbach, J, Freyer, C, Amunts, A, Wredenberg, A.
登録日2024-11-08
公開日2025-07-09
実験手法ELECTRON MICROSCOPY (2.85 Å)
主引用文献The mitochondrial methylation potential gates mitoribosome assembly.
Nat Commun, 16, 2025
7SFR
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BU of 7sfr by Molmil
Unmethylated Mtb Ribosome 50S with SEQ-9
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Xing, Z, Cui, Z, Zhang, J, TB Structural Genomics Consortium (TBSGC)
登録日2021-10-04
公開日2022-10-12
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Discovery of natural-product-derived sequanamycins as potent oral anti-tuberculosis agents.
Cell, 186, 2023
4XS3
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BU of 4xs3 by Molmil
Crystal structure of a metabolic reductase with (E)-1-benzyl-5-((1-methyl-5-oxo-2-thioxoimidazolidin-4-ylidene)methyl)pyridin-2(1H)-one
分子名称: (E)-1-benzyl-5-((1-methyl-5-oxo-2-thioxoimidazolidin-4-ylidene)methyl)pyridin-2(1H)-one, Isocitrate dehydrogenase [NADP] cytoplasmic, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Zheng, B, Wu, F, Jiang, H, Kogiso, M, Yao, Y, Zhou, C, Li, X, Song, Y.
登録日2015-01-21
公開日2016-07-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.291 Å)
主引用文献Inhibition of Cancer-Associated Mutant Isocitrate Dehydrogenases by 2-Thiohydantoin Compounds.
J.Med.Chem., 58, 2015
9IK9
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BU of 9ik9 by Molmil
Cryo-EM Structure of SST analogs bond SSTR1-Gi complex
分子名称: (4J2)(DCY)(DTY)(DTR)K(DVA)(DCY)(ALO)(NH2), Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Wong, T.S, Zeng, Z.C, Xiong, T.T, Gan, S.Y, Du, Y.
登録日2024-06-26
公開日2025-04-30
最終更新日2025-06-25
実験手法ELECTRON MICROSCOPY (3.37 Å)
主引用文献Structural insights into the binding modes of lanreotide and pasireotide with somatostatin receptor 1.
Acta Pharm Sin B, 15, 2025
4XRX
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BU of 4xrx by Molmil
Crystal structure of a metabolic reductase with (E)-5-((1-methyl-5-oxo-2-thioxoimidazolidin-4-ylidene)methyl)pyridin-2(1H)-one
分子名称: 5-[(E)-(1-methyl-5-oxo-2-thioxoimidazolidin-4-ylidene)methyl]pyridin-2(1H)-one, Isocitrate dehydrogenase [NADP] cytoplasmic, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Zheng, B, Wu, F, Jiang, H, Kogiso, M, Yao, Y, Zhou, C, Li, X, Song, Y.
登録日2015-01-21
公開日2015-12-09
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Inhibition of Cancer-Associated Mutant Isocitrate Dehydrogenases by 2-Thiohydantoin Compounds.
J.Med.Chem., 58, 2015
9IK8
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Cryo-EM Structure of SSTR1-Gi SST analogs complex
分子名称: DTR-LYS-TY5-PHA-A1D5E-004, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Wong, T.S, Zeng, Z.C, Xiong, T.T, Gan, S.Y, Du, Y.
登録日2024-06-26
公開日2025-04-30
最終更新日2025-06-25
実験手法ELECTRON MICROSCOPY (2.82 Å)
主引用文献Structural insights into the binding modes of lanreotide and pasireotide with somatostatin receptor 1.
Acta Pharm Sin B, 15, 2025
8W4P
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BU of 8w4p by Molmil
Structure of PSII-FCPII-I/J/K complex in the PSII-FCPII supercomplex from Cyclotella meneghiniana
分子名称: (3S,3'R,5R,6S,7cis)-7',8'-didehydro-5,6-dihydro-5,6-epoxy-beta,beta-carotene-3,3'-diol, (3S,3'S,5R,5'R,6S,6'R,8'R)-3,5'-dihydroxy-8-oxo-6',7'-didehydro-5,5',6,6',7,8-hexahydro-5,6-epoxy-beta,beta-caroten-3'- yl acetate, CHLOROPHYLL A, ...
著者Shen, L.L, Li, Z.H, Shen, J.R, Wang, W.D.
登録日2023-08-24
公開日2023-12-20
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (3.48 Å)
主引用文献Structural insights into photosystem II supercomplex and trimeric FCP antennae of a centric diatom Cyclotella meneghiniana.
Nat Commun, 14, 2023
8W4O
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Structure of PSII-FCPII-G/H complex in the PSII-FCPII supercomplex from Cyclotella meneghiniana
分子名称: (1~{R})-3,5,5-trimethyl-4-[(1~{E},3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E})-3,7,12,16-tetramethyl-18-[(4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohexen-1-yl]octadeca-1,3,5,7,9,11,13,15-octaen-17-ynyl]cyclohex-3-en-1-ol, (3S,3'R,5R,6S,7cis)-7',8'-didehydro-5,6-dihydro-5,6-epoxy-beta,beta-carotene-3,3'-diol, (3S,3'S,5R,5'R,6S,6'R,8'R)-3,5'-dihydroxy-8-oxo-6',7'-didehydro-5,5',6,6',7,8-hexahydro-5,6-epoxy-beta,beta-caroten-3'- yl acetate, ...
著者Shen, L.L, Li, Z.H, Shen, J.R, Wang, W.D.
登録日2023-08-24
公開日2023-12-20
最終更新日2025-06-18
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献Structural insights into photosystem II supercomplex and trimeric FCP antennae of a centric diatom Cyclotella meneghiniana.
Nat Commun, 14, 2023
7E6Q
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Crystal structure of influenza A virus neuraminidase N5 complexed with 4'-phenyl-1,2,3-triazolylated oseltamivir carboxylate
分子名称: (3R,4R,5S)-4-acetamido-3-pentan-3-yloxy-5-(4-phenyl-1,2,3-triazol-1-yl)cyclohexene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Wang, P.F, Babayemi, O.O, Li, C.N, Fu, L.F, Zhang, S.S, Qi, J.X, Lv, X, Li, X.B.
登録日2021-02-23
公開日2021-03-17
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure-based design of 5'-substituted 1,2,3-triazolylated oseltamivir derivatives as potent influenza neuraminidase inhibitors.
Rsc Adv, 11, 2021
1E9K
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The structure of the RACK1 interaction sites located within the unique N-terminal region of the cAMP-specific phosphodiesterase, PDE4D5.
分子名称: cAMP-specific 3',5'-cyclic phosphodiesterase 4D
著者Bolger, G.B, Smith, K.J, McCahill, A, Hyde, E.I, Steele, M.R, Houslay, M.D.
登録日2000-10-20
公開日2001-10-18
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献1H NMR structural and functional characterisation of a cAMP-specific phosphodiesterase-4D5 (PDE4D5) N-terminal region peptide that disrupts PDE4D5 interaction with the signalling scaffold proteins, beta-arrestin and RACK1.
Cell. Signal., 19, 2007

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