3STA
 
 | | Crystal structure of ClpP in tetradecameric form from Staphylococcus aureus | | 分子名称: | ATP-dependent Clp protease proteolytic subunit | | 著者 | Zhang, J, Ye, F, Lan, L, Jiang, H, Luo, C, Yang, C.-G. | | 登録日 | 2011-07-09 | | 公開日 | 2011-09-07 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Structural switching of Staphylococcus aureus Clp protease: a key to understanding protease dynamics
J.Biol.Chem., 286, 2011
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5X16
 | | Sirt6 apo structure | | 分子名称: | GLYCEROL, NAD-dependent protein deacetylase sirtuin-6, TERTIARY-BUTYL ALCOHOL, ... | | 著者 | Zhang, J, Huang, Z, Song, K. | | 登録日 | 2017-01-24 | | 公開日 | 2018-07-04 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Sirt6 apo structure
To Be Published
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5Z8H
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7XR5
 | | Crystal structure of imine reductase with NAPDH from Streptomyces albidoflavus | | 分子名称: | 3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57-nonadecaoxanonapentacontane-1,59-diol, 6-phosphogluconate dehydrogenase NAD-binding, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Zhang, J, Chen, R.C, Gao, S.S. | | 登録日 | 2022-05-09 | | 公開日 | 2022-10-19 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Actinomycetes-derived imine reductases with a preference towards bulky amine substrates.
Commun Chem, 5, 2022
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5ZY9
 | | Structural basis for a tRNA synthetase | | 分子名称: | (1R,2R)-2-[(2S,4E,6E,8R,9S,11R,13S,15S,16S)-7-cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-dien-2-yl]cyclopentanecarboxylic acid, Threonyl-tRNA synthase, ZINC ION | | 著者 | Zhang, J. | | 登録日 | 2018-05-23 | | 公開日 | 2019-06-12 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis for inhibition of
translational functions on a tRNA synthetase
To Be Published
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7XE8
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7WNN
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7U8C
 | | Crystal structure of Mesothelin C-terminal peptide-MORAb 15B6 FAB complex | | 分子名称: | MORab 15B6 Fab heavy chain, MORab 15B6 Fab light chain, Mesothelin, ... | | 著者 | Zhan, J, Esser, L, Xia, D. | | 登録日 | 2022-03-08 | | 公開日 | 2022-06-08 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Highly active CAR T cells that bind to a juxtamembrane region of mesothelin and are not blocked by shed mesothelin.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7N1W
 | | Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Zhang, J, Cai, Y.F, Xiao, T.S, Rawson, S, Peng, H.Q, Sterling, S.M, Walsh Jr, R.M, Volloch, S.R, Chen, B. | | 登録日 | 2021-05-28 | | 公開日 | 2021-07-07 | | 最終更新日 | 2021-08-18 | | 実験手法 | ELECTRON MICROSCOPY (3.33 Å) | | 主引用文献 | Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants.
Science, 373, 2021
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7N1Y
 | | Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Zhang, J, Cai, Y.F, Xiao, T.S, Rawson, S, Peng, H.Q, Sterling, S.M, Walsh Jr, R.M, Volloch, S.R, Chen, B. | | 登録日 | 2021-05-28 | | 公開日 | 2021-07-07 | | 最終更新日 | 2021-08-18 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants.
Science, 373, 2021
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7N1U
 | | Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Zhang, J, Cai, Y.F, Xiao, T.S, Rawson, S, Peng, H.Q, Sterling, S.M, Walsh Jr, R.M, Volloch, S.R, Chen, B. | | 登録日 | 2021-05-28 | | 公開日 | 2021-07-07 | | 最終更新日 | 2021-08-18 | | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | | 主引用文献 | Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants.
Science, 373, 2021
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7N1V
 | | Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Zhang, J, Cai, Y.F, Xiao, T.S, Rawson, S, Peng, H.Q, Sterling, S.M, Walsh Jr, R.M, Volloch, S.R, Chen, B. | | 登録日 | 2021-05-28 | | 公開日 | 2021-07-07 | | 最終更新日 | 2021-08-18 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants.
Science, 373, 2021
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7N1X
 | | Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Zhang, J, Cai, Y.F, Xiao, T.S, Rawson, S, Peng, H.Q, Sterling, S.M, Walsh Jr, R.M, Volloch, S.R, Chen, B. | | 登録日 | 2021-05-28 | | 公開日 | 2021-07-07 | | 最終更新日 | 2021-08-18 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants.
Science, 373, 2021
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7N1T
 | | Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Zhang, J, Cai, Y.F, Xiao, T.S, Rawson, S, Peng, H.Q, Sterling, S.M, Walsh Jr, R.M, Volloch, S.R, Chen, B. | | 登録日 | 2021-05-28 | | 公開日 | 2021-07-07 | | 最終更新日 | 2021-08-18 | | 実験手法 | ELECTRON MICROSCOPY (3.44 Å) | | 主引用文献 | Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants.
Science, 373, 2021
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7N1Q
 | | Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Zhang, J, Cai, Y.F, Xiao, T.S, Rawson, S, Peng, H.Q, Sterling, S.M, Walsh Jr, R.M, Volloch, S.R, Chen, B. | | 登録日 | 2021-05-28 | | 公開日 | 2021-07-07 | | 最終更新日 | 2021-08-18 | | 実験手法 | ELECTRON MICROSCOPY (3.44 Å) | | 主引用文献 | Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants.
Science, 373, 2021
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6XR8
 | | Distinct conformational states of SARS-CoV-2 spike protein | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Zhang, J, Cai, Y.F, Xiao, T.S, Peng, H.Q, Sterling, S.M, Walsh Jr, R.M, Rawson, S, Volloch, S.R, Chen, B. | | 登録日 | 2020-07-11 | | 公開日 | 2020-07-22 | | 最終更新日 | 2020-11-25 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Distinct conformational states of SARS-CoV-2 spike protein.
Science, 369, 2020
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8XAI
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4GVA
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3VHZ
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7N98
 | | Cryo-EM structure of MFSD2A | | 分子名称: | Sodium-dependent lysophosphatidylcholine symporter 1 | | 著者 | Zhang, J, Feng, L. | | 登録日 | 2021-06-17 | | 公開日 | 2021-08-04 | | 最終更新日 | 2021-09-01 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structure and mechanism of blood-brain-barrier lipid transporter MFSD2A.
Nature, 596, 2021
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2RBE
 | | The discovery of 2-anilinothiazolones as 11beta-HSD1 inhibitors | | 分子名称: | (5R)-2-[(2-fluorophenyl)amino]-5-(1-methylethyl)-1,3-thiazol-4(5H)-one, Corticosteroid 11-beta-dehydrogenase isozyme 1, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Zhang, J, Jordan, S.R, Li, V. | | 登録日 | 2007-09-18 | | 公開日 | 2008-01-15 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The discovery of 2-anilinothiazolones as 11beta-HSD1 inhibitors.
Bioorg.Med.Chem.Lett., 17, 2007
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7YUK
 | | Complex structure of BANP BEN domain bound to DNA | | 分子名称: | DNA (5'-D(*CP*TP*CP*TP*CP*GP*CP*GP*AP*GP*AP*G)-3'), GLYCEROL, Protein BANP | | 著者 | Zhang, J, Xiao, Y.Q, Chen, Y.X, Liu, K, Min, J.R. | | 登録日 | 2022-08-17 | | 公開日 | 2023-04-26 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | Structural insights into DNA recognition by the BEN domain of the transcription factor BANP.
J.Biol.Chem., 299, 2023
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7YUG
 | | Structure of human BANP BEN domain | | 分子名称: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, BROMIDE ION, CHLORIDE ION, ... | | 著者 | Zhang, J, Xiao, Y.Q, Chen, Y.X, Liu, K, Min, J.R. | | 登録日 | 2022-08-17 | | 公開日 | 2023-04-26 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Structural insights into DNA recognition by the BEN domain of the transcription factor BANP.
J.Biol.Chem., 299, 2023
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7DDE
 | | Cryo-EM structure of the Ape4 and Nbr1 complex | | 分子名称: | Aspartyl aminopeptidase 1,ZZ-type zinc finger-containing protein P35G2.11c,Maltose/maltodextrin-binding periplasmic protein, ZINC ION | | 著者 | Zhang, J, Ye, K. | | 登録日 | 2020-10-28 | | 公開日 | 2021-07-14 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (2.26 Å) | | 主引用文献 | Molecular and structural mechanisms of ZZ domain-mediated cargo selection by Nbr1.
Embo J., 40, 2021
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7DD9
 | | Cryo-EM structure of the Ams1 and Nbr1 complex | | 分子名称: | Alpha-mannosidase,ZZ-type zinc finger-containing protein P35G2.11c,Maltose/maltodextrin-binding periplasmic protein, ZINC ION | | 著者 | Zhang, J, Ye, K. | | 登録日 | 2020-10-28 | | 公開日 | 2021-07-14 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | | 主引用文献 | Molecular and structural mechanisms of ZZ domain-mediated cargo selection by Nbr1.
Embo J., 40, 2021
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