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8EOX
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BU of 8eox by Molmil
Precisely patterned nanofibers made from extendable protein multiplexes
分子名称: C4HR1_4r
著者Bera, A.K, Bethel, N.P.
登録日2022-10-04
公開日2023-08-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Precisely patterned nanofibres made from extendable protein multiplexes.
Nat.Chem., 15, 2023
1ZO9
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BU of 1zo9 by Molmil
Crystal Structure Of The Wild Type Heme Domain Of P450BM-3 with N-palmitoylmethionine
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Bifunctional P-450:NADPH-P450 reductase, GLYCEROL, ...
著者Hegda, A, Chen, B, Tomchick, D.R, Bondlela, M, Haines, D.C, Schaffer, N, Machius, M, Graham, S.E, Peterson, J.A.
登録日2005-05-12
公開日2006-08-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Interactions of substrates at the surface of P450s can greatly enhance substrate potency.
Biochemistry, 46, 2007
5WEV
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BU of 5wev by Molmil
Identification of an imidazopyridine scaffold to generate potent and selective TYK2 inhibitors that demonstrate activity in an in vivo psoriasis model
分子名称: N-[2-(2,6-dichlorophenyl)-1H-imidazo[4,5-c]pyridin-4-yl]cyclopropanecarboxamide, Tyrosine-protein kinase JAK2
著者Ultsch, M.H, Magnuson, S.
登録日2017-07-10
公開日2017-09-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.854 Å)
主引用文献Identification of an imidazopyridine scaffold to generate potent and selective TYK2 inhibitors that demonstrate activity in an in vivo psoriasis model.
Bioorg. Med. Chem. Lett., 27, 2017
5WAL
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BU of 5wal by Molmil
Identification of an imidazopyridine scaffold to generate potent and selective TYK2 inhibitors that demonstrate activity in an in vivo psoriasis model
分子名称: N-[2-(2,6-dichlorophenyl)-1H-imidazo[4,5-c]pyridin-4-yl]cyclopropanecarboxamide, Non-receptor tyrosine-protein kinase TYK2
著者Ultsch, M.H, Magnuson, S.
登録日2017-06-26
公開日2017-09-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Identification of an imidazopyridine scaffold to generate potent and selective TYK2 inhibitors that demonstrate activity in an in vivo psoriasis model.
Bioorg. Med. Chem. Lett., 27, 2017
3EFW
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BU of 3efw by Molmil
Structure of AuroraA with pyridyl-pyrimidine urea inhibitor
分子名称: 1-[3-methyl-4-({3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-yl}oxy)phenyl]-3-[3-(trifluoromethyl)phenyl]urea, SULFATE ION, Serine/threonine-protein kinase 6
著者Bellon, S.F, Cee, V, Hughes, P, Geuns-Meyer, S, Whittington, D.
登録日2008-09-10
公開日2008-12-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Pyridyl-pyrimidine benzimidazole derivatives as potent, selective, and orally bioavailable inhibitors of Tie-2 kinase.
Bioorg.Med.Chem.Lett., 19, 2009
8FBO
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BU of 8fbo by Molmil
Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains
分子名称: KWOCA_102
著者Wang, J.Y, Khmelinskaia, A, Bera, A.K, King, N.P.
登録日2022-11-29
公開日2023-03-22
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains.
Proc.Natl.Acad.Sci.USA, 120, 2023
8FBN
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BU of 8fbn by Molmil
Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains
分子名称: KWOCA_73
著者Wang, J.Y, Khmelinskaia, A, Bera, A.K, King, N.P.
登録日2022-11-29
公開日2023-03-22
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3.04 Å)
主引用文献Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains.
Proc.Natl.Acad.Sci.USA, 120, 2023
8FBJ
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BU of 8fbj by Molmil
Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains
分子名称: KWOCA_60
著者Wang, J.Y, Khmelinskaia, A, Bera, A.K, King, N.P.
登録日2022-11-29
公開日2023-03-22
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains.
Proc.Natl.Acad.Sci.USA, 120, 2023
8FBI
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BU of 8fbi by Molmil
Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains
分子名称: KWOCA_39
著者Wang, J.Y, Khmelinskaia, A, Bera, A.K, King, N.P.
登録日2022-11-29
公開日2023-03-22
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3.61 Å)
主引用文献Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains.
Proc.Natl.Acad.Sci.USA, 120, 2023
8FBK
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BU of 8fbk by Molmil
Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains
分子名称: KWOCA_65
著者Wang, J.Y, Khmelinskaia, A, Bera, A.K, King, N.P.
登録日2022-11-29
公開日2023-03-22
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains.
Proc.Natl.Acad.Sci.USA, 120, 2023
8FIQ
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BU of 8fiq by Molmil
Multi-state design of two-state switchable hinge proteins
分子名称: cs207AB
著者Bera, A.K, Leung, P.J.Y, Baker, D.
登録日2022-12-16
公開日2023-08-16
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Design of stimulus-responsive two-state hinge proteins.
Science, 381, 2023
8FVT
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BU of 8fvt by Molmil
Multi-state design of two-state switchable hinge proteins
分子名称: 3hb12
著者Bera, A.K, Broerman, A, Baker, D.
登録日2023-01-19
公開日2023-08-16
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.07 Å)
主引用文献Design of stimulus-responsive two-state hinge proteins.
Science, 381, 2023
8FIN
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BU of 8fin by Molmil
Multi-state design of two-state switchable hinge proteins
分子名称: cs207A
著者Bera, A.K, Leung, P.J.Y, Baker, D.
登録日2022-12-16
公開日2023-08-16
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Design of stimulus-responsive two-state hinge proteins.
Science, 381, 2023
8FIH
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BU of 8fih by Molmil
Multi-state design of two-state switchable hinge proteins
分子名称: 3hb05, PHOSPHATE ION
著者Bera, A.K, Broerman, A, Baker, D.
登録日2022-12-16
公開日2023-08-16
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Design of stimulus-responsive two-state hinge proteins.
Science, 381, 2023
8FIT
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BU of 8fit by Molmil
Multi-state design of two-state switchable hinge proteins
分子名称: cs074A
著者Bera, A.K, Praetorius, F, Baker, D.
登録日2022-12-16
公開日2023-08-16
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Design of stimulus-responsive two-state hinge proteins.
Science, 381, 2023
3ET2
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BU of 3et2 by Molmil
Structure of PPARdelta with 3-[5-Methoxy-1-(4-methoxy-benzenesulfonyl)-1H-indol-3-yl]-propionic acid
分子名称: 1-BUTANOL, 3-{5-methoxy-1-[(4-methoxyphenyl)sulfonyl]-1H-indol-3-yl}propanoic acid, Peroxisome proliferator-activated receptor delta
著者Zhang, K.Y.J, Wang, W.
登録日2008-10-06
公開日2009-02-17
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Scaffold-based discovery of indeglitazar, a PPAR pan-active anti-diabetic agent
Proc.Natl.Acad.Sci.USA, 106, 2009
8FJF
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BU of 8fjf by Molmil
The three-repeat design H10
分子名称: H10
著者Bera, A.K, An, L, Baker, D.
登録日2022-12-19
公開日2023-09-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Hallucination of closed repeat proteins containing central pockets.
Nat.Struct.Mol.Biol., 30, 2023
8FJE
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BU of 8fje by Molmil
The five-repeat design E8
分子名称: E8
著者Bera, A.K, An, L, Baker, D.
登録日2022-12-19
公開日2023-09-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Hallucination of closed repeat proteins containing central pockets.
Nat.Struct.Mol.Biol., 30, 2023
8FJG
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BU of 8fjg by Molmil
The two-repeat design H12
分子名称: H12
著者Bera, A.K, An, L, Baker, D.
登録日2022-12-19
公開日2023-09-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Hallucination of closed repeat proteins containing central pockets.
Nat.Struct.Mol.Biol., 30, 2023
7BHD
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BU of 7bhd by Molmil
FimH in complex with alpha1,6 core-fucosylated oligomannose-3, crystallized in the trigonal space group
分子名称: NICKEL (II) ION, SULFATE ION, Type 1 fimbrin D-mannose specific adhesin, ...
著者Bridot, C, Bouckaert, J, Krammer, E.-M.
登録日2021-01-11
公開日2022-07-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural insights into a cooperative switch between one and two FimH bacterial adhesins binding pauci- and high-mannose type N-glycan receptors.
J.Biol.Chem., 299, 2023
8FG6
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BU of 8fg6 by Molmil
Design of amyloidogenic peptide traps
分子名称: C104.1, amyloidogenic peptide
著者Sahtoe, D.D, Bera, A.K, Baker, D.
登録日2022-12-12
公開日2024-03-20
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Design of amyloidogenic peptide traps.
Nat.Chem.Biol., 2024
8GA9
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BU of 8ga9 by Molmil
C4HR1_4r: Extendable repeat protein tetramer
分子名称: C4HR1_4r
著者Bethel, N.P, Borst, A.J.
登録日2023-02-22
公開日2023-08-30
最終更新日2023-12-20
実験手法ELECTRON MICROSCOPY (3.71 Å)
主引用文献Precisely patterned nanofibres made from extendable protein multiplexes.
Nat.Chem., 15, 2023
8G8I
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BU of 8g8i by Molmil
C3HR3_9r_shift4: Extendable repeat protein fiber
分子名称: C3HR3_9r_shift4
著者Bethel, N.P, Borst, A.J.
登録日2023-02-17
公開日2023-08-30
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.92 Å)
主引用文献Precisely patterned nanofibres made from extendable protein multiplexes.
Nat.Chem., 15, 2023
8GAQ
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BU of 8gaq by Molmil
C5HR2_4r: Extendable repeat protein pentamer
分子名称: C5HR2_4r
著者Bethel, N.P, Borst, A.J.
登録日2023-02-23
公開日2023-08-30
最終更新日2023-12-20
実験手法ELECTRON MICROSCOPY (3.73 Å)
主引用文献Precisely patterned nanofibres made from extendable protein multiplexes.
Nat.Chem., 15, 2023
8GAA
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BU of 8gaa by Molmil
C6HR1_4r: Extendable repeat protein hexamer
分子名称: C6HR1_4r
著者Bethel, N.P, Borst, A.J, Baker, D.
登録日2023-02-22
公開日2023-08-30
最終更新日2023-12-20
実験手法ELECTRON MICROSCOPY (4.24 Å)
主引用文献Precisely patterned nanofibres made from extendable protein multiplexes.
Nat.Chem., 15, 2023

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