3T0Z
| Hsp90 N-terminal domain bound to ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-alpha, MAGNESIUM ION | 著者 | Li, J. | 登録日 | 2011-07-21 | 公開日 | 2012-01-25 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.192 Å) | 主引用文献 | Structure insights into mechanisms of ATP hydrolysis and the activation of human heat-shock protein 90. Acta Biochim Biophys Sin (Shanghai), 44, 2012
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8GUG
| Structure of VPA0770 toxin bound to VPA0769 antitoxin in Vibrio parahaemolyticus | 分子名称: | DUF2384 domain-containing protein, RES domain-containing protein | 著者 | Song, X.J, Zhang, Y, Xu, Y.Y, Lin, Z. | 登録日 | 2022-09-12 | 公開日 | 2023-07-26 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Structural insights of the toxin-antitoxin system VPA0770-VPA0769 in Vibrio parahaemolyticus. Int.J.Biol.Macromol., 242, 2023
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8H59
| A fungal MAP kinase in complex with an inhibitor | 分子名称: | Mitogen-activated protein kinase MPS1, ~{N}-[(2~{S})-3-(1~{H}-indol-3-yl)-1-(methylamino)-1-oxidanylidene-propan-2-yl]-8-[2-methoxy-5-(trifluoromethyloxy)phenyl]-1,6-naphthyridine-2-carboxamide | 著者 | Kong, Z, Zhang, X, Wang, D, Liu, J. | 登録日 | 2022-10-12 | 公開日 | 2023-02-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structure-Aided Identification of an Inhibitor Targets Mps1 for the Management of Plant-Pathogenic Fungi. Mbio, 14, 2023
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8HFZ
| Cryo-EM structure of SARS-CoV-2 prototype spike protein in complex with white-tailed deer ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ... | 著者 | Han, P, Meng, Y.M, Qi, J.X. | 登録日 | 2022-11-13 | 公開日 | 2023-08-30 | 最終更新日 | 2023-10-25 | 実験手法 | ELECTRON MICROSCOPY (2.71 Å) | 主引用文献 | Structural basis of white-tailed deer, Odocoileus virginianus , ACE2 recognizing all the SARS-CoV-2 variants of concern with high affinity. J.Virol., 97, 2023
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8HFY
| SARS-CoV-2 Omicron BA.1 spike protein receptor-binding domain in complex with white-tailed deer ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ... | 著者 | Han, P, Meng, Y.M, Qi, J.X. | 登録日 | 2022-11-13 | 公開日 | 2023-08-30 | 最終更新日 | 2023-10-25 | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | 主引用文献 | Structural basis of white-tailed deer, Odocoileus virginianus , ACE2 recognizing all the SARS-CoV-2 variants of concern with high affinity. J.Virol., 97, 2023
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8HFX
| Cryo-EM structure of SARS-CoV-2 Omicron BA.1 spike protein in complex with white-tailed deer ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ... | 著者 | Han, P, Meng, Y.M, Qi, J.X. | 登録日 | 2022-11-13 | 公開日 | 2023-08-30 | 最終更新日 | 2023-10-25 | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | 主引用文献 | Structural basis of white-tailed deer, Odocoileus virginianus , ACE2 recognizing all the SARS-CoV-2 variants of concern with high affinity. J.Virol., 97, 2023
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8HG0
| Cryo-EM structure of SARS-CoV-2 prototype spike protein receptor-binding domain in complex with white-tailed deer ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, Spike protein S1, ... | 著者 | Han, P, Meng, Y.M, Qi, J.X. | 登録日 | 2022-11-13 | 公開日 | 2023-08-30 | 最終更新日 | 2023-10-25 | 実験手法 | ELECTRON MICROSCOPY (3.51 Å) | 主引用文献 | Structural basis of white-tailed deer, Odocoileus virginianus , ACE2 recognizing all the SARS-CoV-2 variants of concern with high affinity. J.Virol., 97, 2023
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3OQ1
| Crystal Structure of 11beta-Hydroxysteroid Dehydrogenase-1 (11b-HSD1) in Complex with Diarylsulfone Inhibitor | 分子名称: | 3-(2-fluoroethyl)-4-({4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]phenyl}sulfonyl)benzonitrile, Corticosteroid 11-beta-dehydrogenase isozyme 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Wang, Z, Sudom, A, Walker, N.P. | 登録日 | 2010-09-02 | 公開日 | 2011-07-20 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The synthesis and SAR of novel diarylsulfone 11beta-HSD1 inhibitors Bioorg.Med.Chem.Lett., 20, 2010
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8IFZ
| Cryo-EM structure of SARS-CoV-2 Omicron BA.4/5 spike protein receptor-binding domain in complex with white-tailed deer ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, Spike protein S1, ... | 著者 | Han, P, Meng, Y.M, Qi, J.X. | 登録日 | 2023-02-20 | 公開日 | 2023-08-30 | 最終更新日 | 2023-10-25 | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | 主引用文献 | Structural basis of white-tailed deer, Odocoileus virginianus , ACE2 recognizing all the SARS-CoV-2 variants of concern with high affinity. J.Virol., 97, 2023
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5JTD
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5JQ2
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8IFY
| Cryo-EM structure of SARS-CoV-2 Omicron BA.4/5 spike protein in complex with white-tailed deer ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ... | 著者 | Han, P, Meng, Y.M, Qi, J.X. | 登録日 | 2023-02-20 | 公開日 | 2023-08-30 | 最終更新日 | 2023-10-25 | 実験手法 | ELECTRON MICROSCOPY (2.55 Å) | 主引用文献 | Structural basis of white-tailed deer, Odocoileus virginianus , ACE2 recognizing all the SARS-CoV-2 variants of concern with high affinity. J.Virol., 97, 2023
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1M8S
| Crystal Structures of Cadmium-binding Acidic Phospholipase A2 from the Venom of Agkistrodon halys pallas at 1.9 Resolution (crystal grown at pH 5.9) | 分子名称: | 1,4-BUTANEDIOL, CADMIUM ION, phospholipase a2 | 著者 | Xu, S, Gu, L, Zhou, Y, Lin, Z. | 登録日 | 2002-07-25 | 公開日 | 2003-02-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structures of cadmium-binding acidic phospholipase A(2) from the venom of Agkistrodon halys Pallas at 1.9A resolutio Biochem.Biophys.Res.Commun., 300, 2003
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1M8R
| Crystal Structures of Cadmium-binding Acidic Phospholipase A2 from the Venom of Agkistrodon halys pallas at 1.9 Resolution (crystal grown at pH 7.4) | 分子名称: | 1,4-BUTANEDIOL, CADMIUM ION, phospholipase A2 | 著者 | Xu, S, Gu, L, Zhou, Y, Lin, Z. | 登録日 | 2002-07-25 | 公開日 | 2003-02-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structures of cadmium-binding acidic phospholipase A(2) from the venom of Agkistrodon halys Pallas at 1.9A resolutio Biochem.Biophys.Res.Commun., 300, 2003
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3HA8
| THE COMPLEX STRUCTURE OF THE MAP KINASE P38/Compound 14b | 分子名称: | Mitogen-activated protein kinase 14, N~2~-{4-[6-(3,4-dihydroquinolin-1(2H)-ylcarbonyl)-1H-benzimidazol-1-yl]-6-ethoxy-1,3,5-triazin-2-yl}-3-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-N-methyl-L-alaninamide | 著者 | Zhao, B, Clark, M.A. | 登録日 | 2009-05-01 | 公開日 | 2009-08-04 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | Design, synthesis and selection of DNA-encoded small-molecule libraries. Nat.Chem.Biol., 5, 2009
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3HA6
| Crystal structure of aurora A in complex with TPX2 and compound 10 | 分子名称: | N~2~-(3,4-dimethoxyphenyl)-N~4~-[2-(2-fluorophenyl)ethyl]-N~6~-quinolin-6-yl-1,3,5-triazine-2,4,6-triamine, Serine/threonine-protein kinase 6, Targeting protein for Xklp2 | 著者 | Zhao, B, Clark, M.A. | 登録日 | 2009-05-01 | 公開日 | 2009-08-04 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | Design, synthesis and selection of DNA-encoded small-molecule libraries. Nat.Chem.Biol., 5, 2009
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3CZR
| Crystal Structure of Human 11-beta-Hydroxysteroid Dehydrogenase (HSD1) in Complex with Arylsulfonylpiperazine Inhibitor | 分子名称: | (2R)-1-[(4-tert-butylphenyl)sulfonyl]-2-methyl-4-(4-nitrophenyl)piperazine, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Corticosteroid 11-beta-dehydrogenase isozyme 1, ... | 著者 | Wang, Z, Sudom, A, Walker, N.P. | 登録日 | 2008-04-29 | 公開日 | 2008-06-17 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Discovery and Initial SAR of Arylsulfonylpiperazine Inhibitors of 11beta-Hydroxysteroid Dehydrogenase Type 1 (11beta-HSD1) Bioorg.Med.Chem.Lett., 18, 2008
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7EN0
| Structure and Activity of SLAC1 Channels for Stomatal Signaling in Leaves | 分子名称: | DIUNDECYL PHOSPHATIDYL CHOLINE, SLow Anion Channel 1, SPHINGOSINE | 著者 | Deng, Y, Kashtoh, H, Wang, Q, Zhen, G, Li, Q, Tang, L, Gao, H, Zhang, C, Qin, L, Su, M, Li, F, Huang, X, Wang, Y, Xie, Q, Clarke, O.B, Hendrickson, W.A, Chen, Y. | 登録日 | 2021-04-15 | 公開日 | 2021-05-19 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.97 Å) | 主引用文献 | Structure and activity of SLAC1 channels for stomatal signaling in leaves. Proc.Natl.Acad.Sci.USA, 118, 2021
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4PPM
| Crystal structure of PigE: a transaminase involved in the biosynthesis of 2-methyl-3-n-amyl-pyrrole (MAP) from Serratia sp. FS14 | 分子名称: | Aminotransferase, MAGNESIUM ION, PYRIDOXAL-5'-PHOSPHATE | 著者 | Lou, X.D, Ran, T.T, Xu, D.Q, Wang, W.W. | 登録日 | 2014-02-27 | 公開日 | 2015-01-14 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of the catalytic domain of PigE: a transaminase involved in the biosynthesis of 2-methyl-3-n-amyl-pyrrole (MAP) from Serratia sp. FS14 Biochem.Biophys.Res.Commun., 447, 2014
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4R3M
| Crystal structure of Human Hsp90 with JR9 | 分子名称: | Heat shock protein HSP 90-alpha, N~3~-benzyl-2-[(6-bromo-1,3-benzodioxol-5-yl)methyl]imidazo[1,2-a]pyrazine-3,8-diamine | 著者 | Li, J, Yang, M, Ren, J, Xiong, B, He, J. | 登録日 | 2014-08-16 | 公開日 | 2014-11-05 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Multi-substituted 8-aminoimidazo[1,2-a]pyrazines by Groebke-Blackburn-Bienayme reaction and their Hsp90 inhibitory activity. Org.Biomol.Chem., 13, 2015
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5ZTL
| Non-cryogenic structure of light-driven chloride pump having an NTQ motif | 分子名称: | CHLORIDE ION, Chloride pumping rhodopsin, OLEIC ACID, ... | 著者 | Yun, J.H, Park, S.Y, Liu, H, Lee, W. | 登録日 | 2018-05-04 | 公開日 | 2018-12-05 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Non-cryogenic structure of a chloride pump provides crucial clues to temperature-dependent channel transport efficiency J. Biol. Chem., 294, 2019
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5ZTK
| Synchrotron structure of light-driven chloride pump having an NTQ motif | 分子名称: | CHLORIDE ION, Chloride pumping rhodopsin, OLEIC ACID, ... | 著者 | Yun, J.H, Park, J.H, Park, S.Y, Lee, W. | 登録日 | 2018-05-04 | 公開日 | 2018-12-05 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Non-cryogenic structure of a chloride pump provides crucial clues to temperature-dependent channel transport efficiency J. Biol. Chem., 294, 2019
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4DXW
| Crystal structure of NavRh, a voltage-gated sodium channel | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, Ion transport protein, ... | 著者 | Zhang, X, Ren, W.L, Yan, C.Y, Wang, J.W, Yan, N. | 登録日 | 2012-02-28 | 公開日 | 2012-05-23 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3.052 Å) | 主引用文献 | Crystal structure of an orthologue of the NaChBac voltage-gated sodium channel Nature, 486, 2012
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7XBH
| The complex structure of RshSTT182/200 RBD bound to human ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, RshSTT182/200 coronavirus receptor binding domain, ... | 著者 | Hu, Y, Liu, K.F, Han, P, Qi, J.X. | 登録日 | 2022-03-21 | 公開日 | 2023-01-11 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.02 Å) | 主引用文献 | Host range and structural analysis of bat-origin RshSTT182/200 coronavirus binding to human ACE2 and its animal orthologs. Embo J., 42, 2023
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7XBF
| The complex structure of RshSTT182/200 RBD-insert2 bound to human ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, RshSTT182/200 coronavirus receptor binding domain insert2, ... | 著者 | Hu, Y, Liu, K.F, Han, P, Qi, J.X. | 登録日 | 2022-03-21 | 公開日 | 2023-01-11 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.51 Å) | 主引用文献 | Host range and structural analysis of bat-origin RshSTT182/200 coronavirus binding to human ACE2 and its animal orthologs. Embo J., 42, 2023
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