5SV1
 
 | | Structure of the ExbB/ExbD complex from E. coli at pH 4.5 | | 分子名称: | Biopolymer transport protein ExbB, Biopolymer transport protein ExbD, MERCURY (II) ION | | 著者 | Celia, H, Botos, I, Lloubes, R, Buchanan, S.K, Noinaj, N. | | 登録日 | 2016-08-04 | | 公開日 | 2016-09-28 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structural insight into the role of the Ton complex in energy transduction.
Nature, 538, 2016
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4N0S
 | | Complex of ERK2 with caffeic acid | | 分子名称: | CAFFEIC ACID, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ... | | 著者 | Kurinov, I, Malakhova, M. | | 登録日 | 2013-10-02 | | 公開日 | 2014-08-27 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.7992 Å) | | 主引用文献 | Caffeic Acid Directly Targets ERK1/2 to Attenuate Solar UV-Induced Skin Carcinogenesis.
Cancer Prev Res (Phila), 7, 2014
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6I1P
 | | Respiratory complex I from Thermus thermophilus with bound NADH | | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ... | | 著者 | Gutierrez-Fernandez, J, Minhas, G.S, Sazanov, L.A. | | 登録日 | 2018-10-29 | | 公開日 | 2020-09-02 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.207 Å) | | 主引用文献 | Key role of quinone in the mechanism of respiratory complex I.
Nat Commun, 11, 2020
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6I0D
 | | Respiratory complex I from Thermus thermophilus with bound Decyl-Ubiquinone | | 分子名称: | 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ... | | 著者 | Gutierrez-Fernandez, J, Minhas, G.S, Sazanov, L.A. | | 登録日 | 2018-10-25 | | 公開日 | 2020-09-02 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Key role of quinone in the mechanism of respiratory complex I.
Nat Commun, 11, 2020
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6JIG
 | | Crystal structure of GMP reductase C318A from Trypanosoma brucei in complex with guanosine 5'-monophosphate | | 分子名称: | GMP reductase, GUANOSINE-5'-MONOPHOSPHATE, POTASSIUM ION | | 著者 | Mase, H, Imamura, A, Nishimura, S, Inui, T. | | 登録日 | 2019-02-21 | | 公開日 | 2020-02-26 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.903 Å) | | 主引用文献 | Allosteric regulation accompanied by oligomeric state changes of Trypanosoma brucei GMP reductase through cystathionine-beta-synthase domain.
Nat Commun, 11, 2020
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5EZJ
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3W9F
 | | Crystal structure of the ankyrin repeat domain of chicken TRPV4 in complex with IP3 | | 分子名称: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Vanilloid receptor-related osmotically activated channel protein | | 著者 | Itoh, Y, Hamada-nakahara, S, Suetsugu, S. | | 登録日 | 2013-04-04 | | 公開日 | 2014-04-09 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | TRPV4 channel activity is modulated by direct interaction of the ankyrin domain to PI(4,5)P2
Nat Commun, 5, 2014
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5EZO
 | | Crystal Structure of PfCyRPA in complex with an invasion-inhibitory antibody Fab. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, PfCyRPA, c12 FAB, ... | | 著者 | Favuzza, P, Pluschke, G, Rudolph, M.G. | | 登録日 | 2015-11-26 | | 公開日 | 2017-01-11 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.63 Å) | | 主引用文献 | Structure of the malaria vaccine candidate antigen CyRPA and its complex with a parasite invasion inhibitory antibody.
Elife, 6, 2017
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5EZL
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5EZN
 | | Crystal Structure of PfCyRPA | | 分子名称: | Cysteine-rich protective antigen | | 著者 | Favuzza, P, Pluschke, G, Rudolph, M.G. | | 登録日 | 2015-11-26 | | 公開日 | 2016-12-07 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Structure of the malaria vaccine candidate antigen CyRPA and its complex with a parasite invasion inhibitory antibody.
Elife, 6, 2017
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3W9G
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3SA0
 | | Complex of ERK2 with norathyriol | | 分子名称: | Mitogen-activated protein kinase 1, SULFATE ION, norathyriol | | 著者 | Kurinov, I, Malakhova, M. | | 登録日 | 2011-06-02 | | 公開日 | 2011-12-14 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.5947 Å) | | 主引用文献 | Norathyriol Suppresses Skin Cancers Induced by Solar Ultraviolet Radiation by Targeting ERK Kinases.
Cancer Res., 72, 2012
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2E83
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3X16
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5EZI
 | | Crystal Structure of Fab of parasite invasion inhibitory antibody c1 - hexagonal form | | 分子名称: | CHLORIDE ION, Fab c12 Light chain, Fab c12 heavy chain, ... | | 著者 | Favuzza, P, Pluschke, G, Rudolph, M.G. | | 登録日 | 2015-11-26 | | 公開日 | 2017-01-25 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | | 主引用文献 | Structure of the malaria vaccine candidate antigen CyRPA and its complex with a parasite invasion inhibitory antibody.
Elife, 6, 2017
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2HAW
 | | Crystal structure of family II Inorganic pyrophosphatase in complex with PNP | | 分子名称: | CHLORIDE ION, FLUORIDE ION, GLYCEROL, ... | | 著者 | Fabrichniy, I.P, Lehtio, L, Oksanen, E, Goldman, A. | | 登録日 | 2006-06-13 | | 公開日 | 2006-11-14 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | A trimetal site and substrate distortion in a family II inorganic pyrophosphatase
J.Biol.Chem., 282, 2007
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6JL8
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6KBR
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6LK4
 | | Crystal structure of GMP reductase from Trypanosoma brucei in complex with guanosine 5'-triphosphate | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, Guanosine 5'-monophosphate Reductase, PHOSPHATE ION | | 著者 | Mase, H, Otani, T, Imamura, A, Nishimura, S, Inui, T. | | 登録日 | 2019-12-18 | | 公開日 | 2020-03-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.503 Å) | | 主引用文献 | Allosteric regulation accompanied by oligomeric state changes of Trypanosoma brucei GMP reductase through cystathionine-beta-synthase domain.
Nat Commun, 11, 2020
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4PAE
 | | Crystal structure of catalase-peroxidase (KatG) W78F mutant from Synechococcus elongatus PCC7942 | | 分子名称: | Catalase-peroxidase, HEME B/C, SODIUM ION, ... | | 著者 | Kamachi, S, Wada, K, Tada, T. | | 登録日 | 2014-04-08 | | 公開日 | 2015-01-14 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.206 Å) | | 主引用文献 | Crystal structure of the catalase-peroxidase KatG W78F mutant from Synechococcus elongatus PCC7942 in complex with the antitubercular pro-drug isoniazid.
Febs Lett., 589, 2015
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4GUE
 | | Structure of N-terminal kinase domain of RSK2 with flavonoid glycoside quercitrin | | 分子名称: | 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl 6-deoxy-alpha-L-mannopyranoside, MAGNESIUM ION, Ribosomal protein S6 kinase alpha-3, ... | | 著者 | Derewenda, U, Utepbergenov, D, Szukalska, G, Derewenda, Z.S. | | 登録日 | 2012-08-29 | | 公開日 | 2013-01-30 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Identification of quercitrin as an inhibitor of the p90 S6 ribosomal kinase (RSK): structure of its complex with the N-terminal domain of RSK2 at 1.8 A resolution.
Acta Crystallogr.,Sect.D, 69, 2013
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3VOZ
 | | Crystal structure of human glutaminase in complex with BPTES | | 分子名称: | Glutaminase kidney isoform, mitochondrial, N,N'-[sulfanediylbis(ethane-2,1-diyl-1,3,4-thiadiazole-5,2-diyl)]bis(2-phenylacetamide), ... | | 著者 | Thangavelu, K, Sivaraman, J. | | 登録日 | 2012-02-23 | | 公開日 | 2012-06-13 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
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3VOY
 | | Crystal structure of human glutaminase in apo form | | 分子名称: | Glutaminase kidney isoform, mitochondrial, SULFATE ION | | 著者 | Thangavelu, K, Sivaraman, J. | | 登録日 | 2012-02-23 | | 公開日 | 2012-06-13 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
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3VP3
 | | Crystal structure of human glutaminase in complex with inhibitor 3 | | 分子名称: | 5,5'-pentane-1,5-diylbis(1,3,4-thiadiazol-2-amine), Glutaminase kidney isoform, mitochondrial, ... | | 著者 | Thangavelu, K, Sivaraman, J. | | 登録日 | 2012-02-23 | | 公開日 | 2012-06-13 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
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3VP1
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