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1JWW
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BU of 1jww by Molmil
NMR characterization of the N-terminal domain of a potential copper-translocating P-type ATPase from Bacillus subtilis
分子名称: Potential copper-transporting ATPase
著者Banci, L, Bertini, I, Ciofi-Baffoni, S, D'Onofrio, M, Gonnelli, L, Marhuenda-Egea, F, Ruiz-Duenas, F.J.
登録日2001-09-05
公開日2002-04-10
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the N-terminal domain of a potential copper-translocating P-type ATPase from Bacillus subtilis in the apo and Cu(I) loaded states.
J.Mol.Biol., 317, 2002
4ZDL
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BU of 4zdl by Molmil
The crystal structure of the T325S mutant of the human holo SepSecS
分子名称: (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, CITRATE ANION, O-phosphoseryl-tRNA(Sec) selenium transferase
著者French, R.L, Simonovic, M.
登録日2015-04-17
公開日2016-04-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Structural basis for early-onset neurological disorders caused by mutations in human selenocysteine synthase.
Sci Rep, 6, 2016
4ZDP
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BU of 4zdp by Molmil
The crystal structure of Y334C mutant of human SepSecS in complex with selenocysteine tRNA (tRNASec)
分子名称: (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, O-phosphoseryl-tRNA(Sec) selenium transferase, PHOSPHATE ION, ...
著者French, R.L, Simonovic, M.
登録日2015-04-17
公開日2016-04-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.703 Å)
主引用文献Structural basis for early-onset neurological disorders caused by mutations in human selenocysteine synthase.
Sci Rep, 6, 2016
4BEH
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BU of 4beh by Molmil
Solution structure of human ribosomal protein P1.P2 heterodimer
分子名称: 60S ACIDIC RIBOSOMAL PROTEIN P1, 60S ACIDIC RIBOSOMAL PROTEIN P2
著者Lee, K.M, Yusa, K, Chu, L.O, Wing-Heng Yu, C, Shaw, P.C, Oono, M, Miyoshi, T, Ito, K, Wong, K.B, Uchiumi, T.
登録日2013-03-10
公開日2013-08-14
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Solution Structure of Human P1P2 Heterodimer Provides Insights Into the Role of Eukaryotic Stalk in Recruiting the Ribosome-Inactivating Protein Trichosanthin to the Ribosome.
Nucleic Acids Res., 41, 2013
7V2G
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BU of 7v2g by Molmil
The 0.98 angstrom structure of the human FABP3 Y19F mutant complexed with palmitic acid
分子名称: Fatty acid-binding protein, heart, HEXAETHYLENE GLYCOL, ...
著者Sugiyama, S, Takahashi, J, Matsuoka, S, Tsuchikawa, H, Sonoyama, M, Inoue, Y, Hayashi, F, Murata, M.
登録日2021-08-09
公開日2022-08-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (0.98 Å)
主引用文献The 0.98 angstrom structure of the human FABP3 Y19F mutant complexed with palmitic acid
To Be Published
4YE8
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BU of 4ye8 by Molmil
The crystal structure of the Y57H mutant of human GlnRS
分子名称: Glutamine--tRNA ligase
著者Ognjenovic, J, Wu, J, Ling, J, Simonovic, M.
登録日2015-02-23
公開日2016-02-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献The crystal structure of human GlnRS provides basis for the development of neurological disorders.
Nucleic Acids Res., 44, 2016
4YYE
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BU of 4yye by Molmil
Crystal structure of the yeast mitochondrial threonyl-tRNA synthetase (MST1) in complex with the canonical tRNAThr and threonyl sulfamoyl adenylate
分子名称: 5'-O-(N-(L-THREONYL)-SULFAMOYL)ADENOSINE, SULFATE ION, Threonine--tRNA ligase, ...
著者Holman, K.M, Simonovic, M.
登録日2015-03-23
公開日2016-01-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献The crystal structure of yeast mitochondrial ThrRS in complex with the canonical threonine tRNA.
Nucleic Acids Res., 44, 2016
7MDL
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BU of 7mdl by Molmil
High-resolution crystal structure of human SepSecS-tRNASec complex
分子名称: (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, CITRATE ANION, O-phosphoseryl-tRNA(Sec) selenium transferase, ...
著者Puppala, A, French, R.L, Simonovic, M.
登録日2021-04-05
公開日2022-11-09
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Structural basis for the tRNA-dependent activation of the terminal complex of selenocysteine synthesis in humans.
Nucleic Acids Res., 2023
4YE6
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BU of 4ye6 by Molmil
The crystal structure of the intact human GlnRS
分子名称: Glutamine--tRNA ligase
著者Ognjenovic, J, Wu, J, Ling, J, Simonovic, M.
登録日2015-02-23
公開日2016-02-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The crystal structure of human GlnRS provides basis for the development of neurological disorders.
Nucleic Acids Res., 44, 2016
4YE9
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BU of 4ye9 by Molmil
The crystal structure of the G45V mutant of human GlnRS
分子名称: Glutamine--tRNA ligase
著者Ognjenovic, J, Wu, J, Ling, J, Simonovic, M.
登録日2015-02-23
公開日2016-02-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The crystal structure of human GlnRS provides basis for the development of neurological disorders.
Nucleic Acids Res., 44, 2016
1KMG
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BU of 1kmg by Molmil
The Solution Structure Of Monomeric Copper-free Superoxide Dismutase
分子名称: Superoxide Dismutase, ZINC ION
著者Banci, L, Bertini, I, Cantini, F, D'Onofrio, M, Viezzoli, M.S.
登録日2001-12-15
公開日2002-10-02
最終更新日2021-10-27
実験手法SOLUTION NMR
主引用文献Structure and dynamics of copper-free SOD: The protein before binding copper.
Protein Sci., 11, 2002
1KQK
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BU of 1kqk by Molmil
Solution Structure of the N-terminal Domain of a Potential Copper-translocating P-type ATPase from Bacillus subtilis in the Cu(I)loaded State
分子名称: COPPER (I) ION, POTENTIAL COPPER-TRANSPORTING ATPASE
著者Banci, L, Bertini, I, Ciofi-Baffoni, S, D'Onofrio, M, Gonnelli, L, Marhuenda-Egea, F.C, Ruiz-Duenas, F.J.
登録日2002-01-07
公開日2002-04-17
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the N-terminal domain of a potential copper-translocating P-type ATPase from Bacillus subtilis in the apo and Cu(I) loaded states.
J.Mol.Biol., 317, 2002
5YGX
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BU of 5ygx by Molmil
Structure of BACE1 in complex with N-(3-((4R,5R,6S)-2-amino-6-(1,1-difluoroethyl)-5-fluoro-4-methyl-5,6-dihydro-4H-1,3-oxazin-4-yl)-4-fluorophenyl)-5-(fluoromethoxy)pyrazine-2-carboxamide
分子名称: Beta-secretase 1, DIMETHYL SULFOXIDE, GLYCEROL, ...
著者Nakahara, K, Fuchino, K, Komano, K, Asada, N, Tadano, G, Hasegawa, T, Yamamoto, T, Sako, Y, Ogawa, M, Unemura, C, Hosono, M, Sakaguchi, G, Ando, S, Ohnishi, S, Kido, Y, Fukushima, T, Dhuyvetter, D, Borghys, H, Gijsen, H, Yamano, Y, Iso, Y, Kusakabe, K.
登録日2017-09-27
公開日2018-08-08
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Discovery of Potent and Centrally Active 6-Substituted 5-Fluoro-1,3-dihydro-oxazine beta-Secretase (BACE1) Inhibitors via Active Conformation Stabilization
J. Med. Chem., 61, 2018
3LXO
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BU of 3lxo by Molmil
The crystal structure of ribonuclease A in complex with thymidine-3'-monophosphate
分子名称: Ribonuclease pancreatic, THYMIDINE-3'-PHOSPHATE
著者Doucet, N, Jayasundera, T.B, Simonovic, M, Loria, J.P.
登録日2010-02-25
公開日2010-04-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.549 Å)
主引用文献The crystal structure of ribonuclease A in complex with thymidine-3'-monophosphate provides further insight into ligand binding.
Proteins, 78, 2010
5UK6
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BU of 5uk6 by Molmil
Structure of Anabaena Sensory Rhodopsin Determined by Solid State NMR Spectroscopy and DEER
分子名称: Bacteriorhodopsin
著者Milikisiyants, S, Wang, S, Munro, R.A, Donohue, M, Ward, M.E, Brown, L.S, Smirnova, T.I, Ladizhansky, V, Smirnov, A.I.
登録日2017-01-20
公開日2017-05-31
最終更新日2020-01-08
実験手法SOLID-STATE NMR
主引用文献Oligomeric Structure of Anabaena Sensory Rhodopsin in a Lipid Bilayer Environment by Combining Solid-State NMR and Long-range DEER Constraints.
J. Mol. Biol., 429, 2017
1J71
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BU of 1j71 by Molmil
Structure of the extracellular aspartic proteinase from Candida tropicalis yeast.
分子名称: Aspartic proteinase, ETHANOL, Tetrapeptide Thr-Ile-Thr-Ser
著者Symersky, J, Monod, M, Foundling, S.I.
登録日2001-05-15
公開日2001-05-23
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献High-resolution structure of the extracellular aspartic proteinase from Candida tropicalis yeast.
Biochemistry, 36, 1997
3UH0
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BU of 3uh0 by Molmil
Crystal structure of the yeast mitochondrial threonyl-tRNA synthetase (MST1) in complex with threonyl sulfamoyl adenylate
分子名称: 5'-O-(N-(L-THREONYL)-SULFAMOYL)ADENOSINE, SULFATE ION, Threonyl-tRNA synthetase, ...
著者Peterson, K.M, Ling, J, Simonovic, I, Cho, C, Soll, D, Simonovic, M.
登録日2011-11-03
公開日2012-02-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Yeast mitochondrial threonyl-tRNA synthetase recognizes tRNA isoacceptors by distinct mechanisms and promotes CUN codon reassignment.
Proc.Natl.Acad.Sci.USA, 109, 2012
3VV6
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BU of 3vv6 by Molmil
Crystal Structure of beta secetase in complex with 2-amino-3-methyl-6-((1S, 2R)-2-phenylcyclopropyl)pyrimidin-4(3H)-one
分子名称: 2-amino-3-methyl-6-[(1S,2R)-2-phenylcyclopropyl]pyrimidin-4(3H)-one, Beta-secretase 1, GLYCEROL, ...
著者Yonezawa, S, Yamamoto, T, Yamakawa, H, Muto, C, Hosono, M, Hattori, K, Higashino, K, Sakagami, M, Togame, H, Tanaka, Y, Nakano, T, Takemoto, H, Arisawa, M, Shuto, S.
登録日2012-07-17
公開日2012-10-24
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Conformational restriction approach to beta-secretase (BACE1) inhibitors: effect of a cyclopropane ring to induce an alternative binding mode
J.Med.Chem., 55, 2012
3VV8
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Crystal structure of beta secetase in complex with 2-amino-3-methyl-6-((1S,2R)-2-(3'-methylbiphenyl-4-yl)cyclopropyl)pyrimidin-4(3H)-one
分子名称: 2-amino-3-methyl-6-[(1S,2R)-2-(3'-methylbiphenyl-4-yl)cyclopropyl]pyrimidin-4(3H)-one, Beta-secretase 1, GLYCEROL
著者Yonezawa, S, Yamamoto, T, Yamakawa, H, Muto, C, Hosono, M, Hattori, K, Higashino, K, Sakagami, M, Togame, H, Tanaka, Y, Nakano, T, Takemoto, H, Arisawa, M, Shuto, S.
登録日2012-07-17
公開日2012-10-24
最終更新日2013-09-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Conformational restriction approach to beta-secretase (BACE1) inhibitors: effect of a cyclopropane ring to induce an alternative binding mode.
J.Med.Chem., 55, 2012
3UGT
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BU of 3ugt by Molmil
Crystal structure of the yeast mitochondrial threonyl-tRNA synthetase - orthorhombic crystal form
分子名称: Threonyl-tRNA synthetase, mitochondrial, ZINC ION
著者Peterson, K.M, Ling, J, Simonovic, I, Cho, C, Soll, D, Simonovic, M.
登録日2011-11-02
公開日2012-02-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Yeast mitochondrial threonyl-tRNA synthetase recognizes tRNA isoacceptors by distinct mechanisms and promotes CUN codon reassignment.
Proc.Natl.Acad.Sci.USA, 109, 2012
3VV7
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BU of 3vv7 by Molmil
Crystal Structure of beta secetase in complex with 2-amino-6-((1S,2R)-2-(3'-methoxybiphenyl-3-yl)cyclopropyl)-3-methylpyrimidin-4(3H)-one
分子名称: 2-amino-6-[(1S,2R)-2-(3'-methoxybiphenyl-3-yl)cyclopropyl]-3-methylpyrimidin-4(3H)-one, Beta-secretase 1, GLYCEROL, ...
著者Yonezawa, S, Yamamoto, T, Yamakawa, H, Muto, C, Hosono, M, Hattori, K, Higashino, K, Sakagami, M, Togame, H, Tanaka, Y, Nakano, T, Takemoto, H, Arisawa, M, Shuto, S.
登録日2012-07-17
公開日2012-10-24
最終更新日2013-09-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Conformational restriction approach to beta-secretase (BACE1) inhibitors: effect of a cyclopropane ring to induce an alternative binding mode.
J.Med.Chem., 55, 2012
3UGQ
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Crystal structure of the apo form of the yeast mitochondrial threonyl-tRNA synthetase determined at 2.1 Angstrom resolution
分子名称: POTASSIUM ION, SULFATE ION, Threonyl-tRNA synthetase, ...
著者Peterson, K.M, Ling, J, Simonovic, I, Cho, C, Soll, D, Simonovic, M.
登録日2011-11-02
公開日2012-02-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Yeast mitochondrial threonyl-tRNA synthetase recognizes tRNA isoacceptors by distinct mechanisms and promotes CUN codon reassignment.
Proc.Natl.Acad.Sci.USA, 109, 2012
3HL2
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BU of 3hl2 by Molmil
The crystal structure of the human SepSecS-tRNASec complex
分子名称: (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, Monothiophosphate, O-phosphoseryl-tRNA(Sec) selenium transferase, ...
著者Palioura, S, Steitz, T.A, Soll, D, Simonovic, M.
登録日2009-05-26
公開日2009-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献The human SepSecS-tRNASec complex reveals the mechanism of selenocysteine formation.
Science, 325, 2009
4K90
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Extracellular metalloproteinase from Aspergillus
分子名称: BORIC ACID, CALCIUM ION, Extracellular metalloproteinase mep, ...
著者Fernandez, D, Russi, S, Vendrell, J, Monod, M, Pallares, I.
登録日2013-04-19
公開日2013-10-23
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A functional and structural study of the major metalloprotease secreted by the pathogenic fungus Aspergillus fumigatus.
Acta Crystallogr.,Sect.D, 69, 2013
1OO8
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CRYSTAL STRUCTURE OF A1PI-PITTSBURGH IN THE NATIVE CONFORMATION
分子名称: Alpha-1-antitrypsin precursor
著者Dementiev, A, Simonovic, M, Volz, K, Gettins, P.G.
登録日2003-03-03
公開日2003-08-05
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Canonical inhibitor-like interactions explain reactivity of alpha1-proteinase inhibitor Pittsburgh and antithrombin with proteinases
J.Biol.Chem., 278, 2003

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