5GUC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5guc by Molmil](/molmil-images/mine/5guc) | Crystal structure of CotB2 (apo form) from Streptomyces melanosporofaciens | 分子名称: | Cyclooctat-9-en-7-ol synthase, FORMIC ACID | 著者 | Tomita, T, Kim, S.-Y, Ozaki, T, Yoshida, A, Kuzuyama, T, Nishiyama, M. | 登録日 | 2016-08-28 | 公開日 | 2017-06-07 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural Insights into the CotB2-Catalyzed Cyclization of Geranylgeranyl Diphosphate to the Diterpene Cyclooctat-9-en-7-ol ACS Chem. Biol., 12, 2017
|
|
6K0G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6k0g by Molmil](/molmil-images/mine/6k0g) | Crystal Structure of UDP-glucose 4-epimerase from Bifidobacterium longum in complex with NAD+ and UDP | 分子名称: | MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, UDP-glucose 4-epimerase, ... | 著者 | Nam, Y.-W, Nishimoto, M, Arakawa, T, Kitaoka, M, Fushinobu, S. | 登録日 | 2019-05-06 | 公開日 | 2019-08-07 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural basis for broad substrate specificity of UDP-glucose 4-epimerase in the human milk oligosaccharide catabolic pathway of Bifidobacterium longum. Sci Rep, 9, 2019
|
|
2AOT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2aot by Molmil](/molmil-images/mine/2aot) | Histamine Methyltransferase Complexed with the Antihistamine Drug Diphenhydramine | 分子名称: | Histamine N-methyltransferase, N-[2-(BENZHYDRYLOXY)ETHYL]-N,N-DIMETHYLAMINE, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Horton, J.R, Sawada, K, Nishibori, M, Cheng, X. | 登録日 | 2005-08-14 | 公開日 | 2005-09-13 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural basis for inhibition of histamine N-methyltransferase by diverse drugs J.Mol.Biol., 353, 2005
|
|
2AOW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2aow by Molmil](/molmil-images/mine/2aow) | Histamine Methyltransferase (Natural Variant I105) Complexed with the Acetylcholinesterase Inhibitor and Altzheimer's Disease Drug Tacrine | 分子名称: | Histamine N-methyltransferase, TACRINE | 著者 | Horton, J.R, Sawada, K, Nishibori, M, Cheng, X. | 登録日 | 2005-08-14 | 公開日 | 2005-09-13 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.97 Å) | 主引用文献 | Structural basis for inhibition of histamine N-methyltransferase by diverse drugs J.Mol.Biol., 353, 2005
|
|
2J5N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2j5n by Molmil](/molmil-images/mine/2j5n) | 1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE FROM THERMUS THERMOPHIRUS WITH BOUND INHIBITOR GLYCINE AND NAD. | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE, ... | 著者 | Inagaki, E, Sakamoto, K, Nishio, M, Yokoyama, S. | 登録日 | 2006-09-19 | 公開日 | 2007-10-16 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Crystal Structure of Ternary Complex of Delta1-Pyrroline-5-Carboxylate Dehydrogenase with Substrate Mimic and Co-Factoer To be Published
|
|
2J40
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2j40 by Molmil](/molmil-images/mine/2j40) | 1-pyrroline-5-carboxylate dehydrogenase from Thermus thermophilus with bound inhibitor L-proline and NAD. | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE, ... | 著者 | Inagaki, E, Sakamoto, K, Nishio, M, Yokoyama, S. | 登録日 | 2006-08-24 | 公開日 | 2007-10-02 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal Structure of Ternary Complex of Delta1-Pyrroline-5-Carboxylate Dehydrogenase with Substrate Mimic and Co-Factoer To be Published
|
|
6KTQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ktq by Molmil](/molmil-images/mine/6ktq) | Crystal structure of catalytic domain of homocitrate synthase from Sulfolobus acidocaldarius (SaHCS(dRAM)) in complex with alpha-ketoglutarate/Zn2+/CoA | 分子名称: | 2-OXOGLUTARIC ACID, COENZYME A, Homocitrate synthase, ... | 著者 | Suzuki, T, Tomita, T, Kuzuyama, T, Nishiyama, M. | 登録日 | 2019-08-28 | 公開日 | 2020-09-02 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Involvement of subdomain II in the recognition of acetyl-CoA revealed by the crystal structure of homocitrate synthase from Sulfolobus acidocaldarius. Febs J., 288, 2021
|
|
5B1Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5b1q by Molmil](/molmil-images/mine/5b1q) | Human herpesvirus 6B tegument protein U14 | 分子名称: | GLYCEROL, U14 protein | 著者 | Wang, B, Nishimura, M, Tang, H, Kawabata, A, Mahmoud, N.F, Khanlari, Z, Hamada, D, Tsuruta, H, Mori, Y. | 登録日 | 2015-12-11 | 公開日 | 2016-04-20 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal Structure of Human Herpesvirus 6B Tegument Protein U14. Plos Pathog., 12, 2016
|
|
3WWN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3wwn by Molmil](/molmil-images/mine/3wwn) | Crystal structure of LysZ from Thermus thermophilus complex with LysW | 分子名称: | OrfF, Putative acetylglutamate kinase-like protein, SULFATE ION, ... | 著者 | Yoshida, A, Tomita, T, Kuzuyama, T, Nishiyama, M. | 登録日 | 2014-06-21 | 公開日 | 2014-11-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural insight into amino group-carrier protein-mediated lysine biosynthesis: crystal structure of the LysZ·LysW complex from Thermus thermophilus. J.Biol.Chem., 290, 2015
|
|
3WWM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3wwm by Molmil](/molmil-images/mine/3wwm) | Crystal structure of LysZ from Thermus thermophilus with ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Putative acetylglutamate kinase-like protein | 著者 | Yoshida, A, Tomita, T, Kuzuyama, T, Nishiyama, M. | 登録日 | 2014-06-21 | 公開日 | 2014-11-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural insight into amino group-carrier protein-mediated lysine biosynthesis: crystal structure of the LysZ·LysW complex from Thermus thermophilus. J.Biol.Chem., 290, 2015
|
|
3WWL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3wwl by Molmil](/molmil-images/mine/3wwl) | Crystal structure of lysine biosynthetic amino acid carrier protein LysW from Thermus thermophilus conjugated with alpha-aminoadipate | 分子名称: | Alpha-aminoadipate carrier protein LysW, ZINC ION | 著者 | Yoshida, A, Tomita, T, Kuzuyama, T, Nishiyama, M. | 登録日 | 2014-06-21 | 公開日 | 2014-11-19 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Structural insight into amino group-carrier protein-mediated lysine biosynthesis: crystal structure of the LysZ·LysW complex from Thermus thermophilus. J.Biol.Chem., 290, 2015
|
|
3BUZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3buz by Molmil](/molmil-images/mine/3buz) | Crystal structure of ia-bTAD-actin complex | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Tsuge, H, Nagahama, M, Oda, M, Iwamoto, S, Utsunomiya, H, Marquez, V.E, Katunuma, N, Nishizawa, M, Sakurai, J. | 登録日 | 2008-01-04 | 公開日 | 2008-05-13 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Structural basis of actin recognition and arginine ADP-ribosylation by Clostridium perfringens iota-toxin Proc.Natl.Acad.Sci.Usa, 105, 2008
|
|
5X3D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5x3d by Molmil](/molmil-images/mine/5x3d) | Crystal structure of HEP-CMP-bound form of cytidylyltransferase (CyTase) domain of Fom1 from Streptomyces wedmorensis | 分子名称: | Phosphoenolpyruvate phosphomutase, [[(2R,3S,4R,5R)-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-(2-hydroxyethyl)phosphinic acid | 著者 | Tomita, T, Cho, S.H, Kuzuyama, T, Nishiyama, M. | 登録日 | 2017-02-04 | 公開日 | 2017-09-13 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Fosfomycin Biosynthesis via Transient Cytidylylation of 2-Hydroxyethylphosphonate by the Bifunctional Fom1 Enzyme ACS Chem. Biol., 12, 2017
|
|
5XOY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5xoy by Molmil](/molmil-images/mine/5xoy) | Crystal structure of LysK from Thermus thermophilus in complex with Lysine | 分子名称: | LYSINE, SULFATE ION, [LysW]-lysine hydrolase | 著者 | Tomita, T, Fujita, S, Hasebe, F, Cho, S.-H, Yoshida, A, Kuzuyama, T, Nishiyama, M. | 登録日 | 2017-05-31 | 公開日 | 2017-09-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Crystal structure of LysK, an enzyme catalyzing the last step of lysine biosynthesis in Thermus thermophilus, in complex with lysine: Insight into the mechanism for recognition of the amino-group carrier protein, LysW Biochem. Biophys. Res. Commun., 491, 2017
|
|
2ZP7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2zp7 by Molmil](/molmil-images/mine/2zp7) | Crystal structure of LysN, alpha-aminoadipate aminotransferase (Leucine complex), from Thermus thermophilus HB27 | 分子名称: | Alpha-aminodipate aminotransferase, LEUCINE, PYRIDOXAL-5'-PHOSPHATE | 著者 | Tomita, T, Miyazaki, T, Miyagawa, T, Fushinobu, S, Kuzuyama, T, Nishiyama, M. | 登録日 | 2008-06-30 | 公開日 | 2009-01-13 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Mechanism for multiple-substrates recognition of alpha-aminoadipate aminotransferase from Thermus thermophilus Proteins, 2008
|
|
3AAW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3aaw by Molmil](/molmil-images/mine/3aaw) | Crystal structure of aspartate kinase from Corynebacterium glutamicum in complex with lysine and threonine | 分子名称: | Aspartokinase, Aspartokinase LysC beta subunit, LYSINE, ... | 著者 | Yoshida, A, Tomita, T, Kuzuyama, T, Nishiyama, M. | 登録日 | 2009-11-27 | 公開日 | 2010-06-23 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Mechanism of concerted inhibition of {alpha}2{beta}2-type heterooligomeric aspartate kinase from Corynebacterium glutamicum J.Biol.Chem., 285, 2010
|
|
3AB2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ab2 by Molmil](/molmil-images/mine/3ab2) | Crystal structure of aspartate kinase from Corynebacterium glutamicum in complex with threonine | 分子名称: | Aspartokinase, THREONINE | 著者 | Yoshida, A, Tomita, T, Kuzuyama, T, Nishiyama, M. | 登録日 | 2009-11-30 | 公開日 | 2010-06-23 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | Mechanism of concerted inhibition of {alpha}2{beta}2-type heterooligomeric aspartate kinase from Corynebacterium glutamicum J.Biol.Chem., 285, 2010
|
|
7WUX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7wux by Molmil](/molmil-images/mine/7wux) | Crystal structure of AziU3/U2 complexed with (5S,6S)-O7-sulfo DADH from Streptomyces sahachiroi | 分子名称: | (2S,5S,6S)-2,6-bis(azanyl)-5-oxidanyl-7-sulfooxy-heptanoic acid, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, AziU2, ... | 著者 | Kurosawa, S, Yoshida, A, Tomita, T, Nishiyama, M. | 登録日 | 2022-02-09 | 公開日 | 2022-09-07 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Molecular Basis for Enzymatic Aziridine Formation via Sulfate Elimination. J.Am.Chem.Soc., 144, 2022
|
|
7WUW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7wuw by Molmil](/molmil-images/mine/7wuw) | Crystal structure of AziU3/U2 from Streptomyces sahachiroi | 分子名称: | AziU2, AziU3, MAGNESIUM ION, ... | 著者 | Kurosawa, S, Yoshida, A, Tomita, T, Nishiyama, M. | 登録日 | 2022-02-09 | 公開日 | 2022-09-07 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Molecular Basis for Enzymatic Aziridine Formation via Sulfate Elimination. J.Am.Chem.Soc., 144, 2022
|
|
1JQD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jqd by Molmil](/molmil-images/mine/1jqd) | Crystal Structure Analysis of Human Histamine Methyltransferase (Thr105 Polymorphic Variant) Complexed with AdoHcy and Histamine | 分子名称: | HISTAMINE, Histamine N-Methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Horton, J.R, Sawada, K, Nishibori, M, Zhang, X, Cheng, X. | 登録日 | 2001-08-06 | 公開日 | 2002-08-06 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Two polymorphic forms of human histamine methyltransferase: structural, thermal, and kinetic comparisons. Structure, 9, 2001
|
|
7Y5Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7y5y by Molmil](/molmil-images/mine/7y5y) | X-ray Structure of Stay-Green (SGR) from Anaerolineae bacterium. | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PHOSPHATE ION, ... | 著者 | Dey, D, Nishijima, M, Kurisu, G, Tanaka, H, Ito, H. | 登録日 | 2022-06-18 | 公開日 | 2022-10-19 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal structure and reaction mechanism of a bacterial Mg-dechelatase homolog from the Chloroflexi Anaerolineae. Protein Sci., 31, 2022
|
|
2Z1Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2z1y by Molmil](/molmil-images/mine/2z1y) | Crystal structure of LysN, alpha-aminoadipate aminotransferase (complexed with N-(5'-phosphopyridoxyl)-L-leucine), from Thermus thermophilus HB27 | 分子名称: | Alpha-aminodipate aminotransferase, LEUCINE, PYRIDOXAL-5'-PHOSPHATE | 著者 | Tomita, T, Miyazaki, T, Miyagawa, T, Fushinobu, S, Kuzuyama, T, Nishiyama, M. | 登録日 | 2007-05-16 | 公開日 | 2008-06-03 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Mechanism of broad substrate specificity of alpha-aminoadipate aminotransferase from Thermus thermophilus To be Published
|
|
3CBF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3cbf by Molmil](/molmil-images/mine/3cbf) | Crystal structure of LysN, alpha-aminoadipate aminotransferase, from Thermus thermophilus HB27 | 分子名称: | (2S)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]hexanedioic acid, Alpha-aminodipate aminotransferase | 著者 | Tomita, T, Miyazaki, T, Miyagawa, T, Fushinobu, S, Kuzuyama, T, Nishiyama, M. | 登録日 | 2008-02-21 | 公開日 | 2009-01-13 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Mechanism for multiple-substrates recognition of alpha-aminoadipate aminotransferase from Thermus thermophilus Proteins, 2008
|
|
7YLZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ylz by Molmil](/molmil-images/mine/7ylz) | |
1JQE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jqe by Molmil](/molmil-images/mine/1jqe) | Crystal Structure Analysis of Human Histamine Methyltransferase (Ile105 Polymorphic Variant) Complexed with AdoHcy and Antimalarial Drug Quinacrine | 分子名称: | Histamine N-Methyltransferase, QUINACRINE, S-ADENOSYL-L-HOMOCYSTEINE, ... | 著者 | Horton, J.R, Sawada, K, Nishibori, M, Zhang, X, Cheng, X. | 登録日 | 2001-08-06 | 公開日 | 2002-08-06 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | Two polymorphic forms of human histamine methyltransferase: structural, thermal, and kinetic comparisons. Structure, 9, 2001
|
|