2J40

1-pyrroline-5-carboxylate dehydrogenase from Thermus thermophilus with bound inhibitor L-proline and NAD.

Summary for 2J40

Entry DOI	10.2210/pdb2j40/pdb
Related	2BHP 2BHQ 2BJA 2BJK 2IY6
Descriptor	1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE, PROLINE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (8 entities in total)
Functional Keywords	glutamate, type ii hyperprolinmia, oxidoreductase, 1-pyrroline-5-carboxylate, proline methabolic pathway
Biological source	THERMUS THERMOPHILUS
Total number of polymer chains	2
Total formula weight	116808.12
Authors	Inagaki, E.,Sakamoto, K.,Nishio, M.,Yokoyama, S. (deposition date: 2006-08-24, release date: 2007-10-02, Last modification date: 2023-12-13)
Primary citation	Inagaki, E.,Sakamoto, K.,Nishio, M.,Yokoyama, S.,Tahirov, T.H. Crystal Structure of Ternary Complex of Delta1-Pyrroline-5-Carboxylate Dehydrogenase with Substrate Mimic and Co-Factoer To be Published,
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation