5V1I
| DNA polymerase beta ternary product complex with 8-oxoG:C and inserted dCTP | 分子名称: | CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*GP*CP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(8OG)P*C)-3'), ... | 著者 | Freudenthal, B.D, Smith, M.R, Whitaker, A.M, Schaich, M.A. | 登録日 | 2017-03-02 | 公開日 | 2017-05-10 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.035 Å) | 主引用文献 | Capturing a mammalian DNA polymerase extending from an oxidized nucleotide. Nucleic Acids Res., 45, 2017
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5V1R
| DNA polymerase beta reactant complex with 8-oxoG:C at the primer terminus and incoming dCTP | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*GP*CP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... | 著者 | Freudenthal, B.D, Smith, M.R, Whitaker, A.M, Schaich, M.A. | 登録日 | 2017-03-02 | 公開日 | 2017-05-10 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.077 Å) | 主引用文献 | Capturing a mammalian DNA polymerase extending from an oxidized nucleotide. Nucleic Acids Res., 45, 2017
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5WN2
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5V1J
| DNA polymerase beta open product complex with 8-oxoG:C and inserted dCTP | 分子名称: | DNA (5'-D(*CP*CP*GP*AP*CP*GP*CP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(8OG)P*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... | 著者 | Freudenthal, B.D, Smith, M.R, Whitaker, A.M, Schaich, M.A. | 登録日 | 2017-03-02 | 公開日 | 2017-05-10 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.616 Å) | 主引用文献 | Capturing a mammalian DNA polymerase extending from an oxidized nucleotide. Nucleic Acids Res., 45, 2017
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5WN3
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5WN1
| APE1 exonuclease product complex | 分子名称: | CALCIUM ION, CHLORIDE ION, DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*G)-3'), ... | 著者 | Freudenthal, B.D, Whitaker, A.M. | 登録日 | 2017-07-31 | 公開日 | 2018-02-28 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Molecular snapshots of APE1 proofreading mismatches and removing DNA damage. Nat Commun, 9, 2018
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5WN5
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5WN4
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6X71
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6P94
| Human APE1 C65A AP-endonuclease product complex | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Whitaker, A.W, Stark, W.J, Freudenthal, B.D. | 登録日 | 2019-06-09 | 公開日 | 2020-01-01 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Functions of the major abasic endonuclease (APE1) in cell viability and genotoxin resistance. Mutagenesis, 35, 2020
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6P93
| Human APE1 K98A AP-endonuclease product complex | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Whitaker, A.W, Stark, W.J, Freudenthal, B.D. | 登録日 | 2019-06-09 | 公開日 | 2020-01-01 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Functions of the major abasic endonuclease (APE1) in cell viability and genotoxin resistance. Mutagenesis, 35, 2020
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7K97
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7K96
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7KXR
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8VF8
| Binary DNA Polymerase Beta bound to DNA containing primer terminal dC base-paired with FapydG | 分子名称: | DNA (5'-D(*CP*CP*GP*AP*CP*CP*(FAP)P*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... | 著者 | Oden, P.N, Ryan, B.J, Freudenthal, B.D. | 登録日 | 2023-12-21 | 公開日 | 2024-05-08 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta. Nucleic Acids Res., 52, 2024
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8VFI
| Ternary DNA Polymerase Beta bound to DNA containing primer terminal FapydG base-paired with a dA | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*GP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... | 著者 | Oden, P.N, Ryan, B.J, Freudenthal, B.D. | 登録日 | 2023-12-21 | 公開日 | 2024-05-15 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta. Nucleic Acids Res., 52, 2024
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8VFF
| Binary DNA Polymerase Beta bound to DNA containing primer terminal FapydG base-paired with a dA | 分子名称: | DNA (5'-D(*CP*CP*GP*AP*CP*GP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(FAP))-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... | 著者 | Oden, P.N, Ryan, B.J, Freudenthal, B.D. | 登録日 | 2023-12-21 | 公開日 | 2024-05-15 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta. Nucleic Acids Res., 52, 2024
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8VFD
| Ternary DNA Polymerase Beta bound to DNA containing template FapydG incoming TTP analog | 分子名称: | 1-{2-deoxy-5-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]-beta-D-threo-pentofuranosyl}-5-methylpyrimidine-2,4(1H,3H)-dione, DNA (5'-D(*CP*CP*GP*AP*CP*(FAP)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... | 著者 | Oden, P.N, Ryan, B.J, Freudenthal, B.D. | 登録日 | 2023-12-21 | 公開日 | 2024-05-08 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta. Nucleic Acids Res., 52, 2024
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8VFA
| Ternary DNA Polymerase Beta bound to DNA containing primer terminal dC base-paired with FapydG | 分子名称: | DNA (5'-D(*CP*CP*GP*AP*CP*CP*(FAP)P*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... | 著者 | Oden, P.N, Ryan, B.J, Freudenthal, B.D. | 登録日 | 2023-12-21 | 公開日 | 2024-05-08 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta. Nucleic Acids Res., 52, 2024
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8VF9
| Binary DNA Polymerase Beta bound to DNA containing primer terminal dA base-paired with FapydG | 分子名称: | DNA (5'-D(*CP*CP*GP*AP*CP*CP*(FAP)P*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... | 著者 | Oden, P.N, Ryan, B.J, Freudenthal, B.D. | 登録日 | 2023-12-21 | 公開日 | 2024-05-08 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta. Nucleic Acids Res., 52, 2024
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8VFH
| Ternary DNA Polymerase Beta bound to DNA containing primer terminal FapydG base-paired with a dC | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*CP*GP*AP*CP*GP*CP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(FAP))-3'), ... | 著者 | Oden, P.N, Ryan, B.J, Freudenthal, B.D. | 登録日 | 2023-12-21 | 公開日 | 2024-05-08 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta. Nucleic Acids Res., 52, 2024
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8VFC
| Binary DNA Polymerase Beta bound to DNA containing primer terminal T base-paired with FapydG | 分子名称: | DNA (5'-D(*CP*CP*GP*AP*CP*GP*(FAP)P*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*T)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... | 著者 | Oden, P.N, Ryan, B.J, Freudenthal, B.D. | 登録日 | 2023-12-21 | 公開日 | 2024-05-08 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta. Nucleic Acids Res., 52, 2024
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8VFG
| Binary DNA Polymerase Beta bound to DNA containing primer terminal FapydG base-paired with a dC | 分子名称: | DNA (5'-D(*CP*CP*GP*AP*CP*GP*CP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(FAP))-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... | 著者 | Oden, P.N, Ryan, B.J, Freudenthal, B.D. | 登録日 | 2023-12-21 | 公開日 | 2024-05-08 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta. Nucleic Acids Res., 52, 2024
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8VFE
| Binary DNA Polymerase Beta bound to DNA containing primer terminal FapydG base-paired with a T | 分子名称: | DNA (5'-D(*CP*CP*GP*AP*CP*GP*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(FAP))-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... | 著者 | Oden, P.N, Ryan, B.J, Freudenthal, B.D. | 登録日 | 2023-12-21 | 公開日 | 2024-05-08 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta. Nucleic Acids Res., 52, 2024
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8VFJ
| Polymerase Beta Host Guest Complex Containing FapydG base paired with TMP | 分子名称: | DNA (5'-D(*CP*CP*GP*AP*CP*GP*GP*CP*GP*CP*AP*TP*(FAP)P*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*TP*AP*TP*GP*CP*GP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... | 著者 | Oden, P.N, Ryan, B.J, Freudenthal, B.D. | 登録日 | 2023-12-21 | 公開日 | 2024-05-08 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta. Nucleic Acids Res., 52, 2024
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