5WN3

APE1 F266A exonuclease substrate complex with a C/T mismatch

Summary for 5WN3

• Entry DOI: 10.2210/pdb5wn3/pdb
• Descriptor: DNA (5'-D(P*TP*CP*GP*AP*CP*GP*GP*AP*TP*CP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DV3))-3'), DNA (5'-D(*GP*GP*AP*TP*CP*CP*GP*TP*CP*GP*AP*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... (9 entities in total)
• Functional Keywords: hydrolase, lyase-dna complex, lyase/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 5
• Total formula weight: 75424.39

Authors

Freudenthal, B.D.,Whitaker, A.M. (deposition date: 2017-07-31, release date: 2018-02-28, Last modification date: 2023-10-04)

• Primary citation: Whitaker, A.M.,Flynn, T.S.,Freudenthal, B.D.; Molecular snapshots of APE1 proofreading mismatches and removing DNA damage.; Nat Commun, 9:399-399, 2018; PubMed: 29374164; DOI: 10.1038/s41467-017-02175-y

Experimental method

X-RAY DIFFRACTION (2 Å)